KEGG   Homo sapiens (human): 3484
Entry
3484              CDS       T01001                                 
Symbol
IGFBP1, AFBP, IBP1, IGF-BP25, PP12, hIGFBP-1
Name
(RefSeq) insulin like growth factor binding protein 1
  KO
K23578  insulin-like growth factor-binding protein 1
Organism
hsa  Homo sapiens (human)
Network
nt06310  CRH-ACTH-cortisol signaling
  Element
N00924  Glucocorticoid receptor signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    3484 (IGFBP1)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Others
   Insulin-like growth factor-binding proteins
    3484 (IGFBP1)
SSDB
Motif
Pfam: Thyroglobulin_1 IGFBP
Other DBs
NCBI-GeneID: 3484
NCBI-ProteinID: NP_000587
OMIM: 146730
HGNC: 5469
Ensembl: ENSG00000146678
Pharos: P08833(Tchem)
UniProt: P08833
Structure
LinkDB
Position
7:45888488..45893660
AA seq 259 aa
MSEVPVARVWLVLLLLTVQVGVTAGAPWQCAPCSAEKLALCPPVSASCSEVTRSAGCGCC
PMCALPLGAACGVATARCARGLSCRALPGEQQPLHALTRGQGACVQESDASAPHAAEAGS
PESPESTEITEEELLDNFHLMAPSEEDHSILWDAISTYDGSKALHVTNIKKWKEPCRIEL
YRVVESLAKAQETSGEEISKFYLPNCNKNGFYHSRQCETSMDGEAGLCWCVYPWNGKRIP
GSPEIRGDPNCQIYFNVQN
NT seq 780 nt   +upstreamnt  +downstreamnt
atgtcagaggtccccgttgctcgcgtctggctggtactgctcctgctgactgtccaggtc
ggcgtgacagccggcgctccgtggcagtgcgcgccctgctccgccgagaagctcgcgctc
tgcccgccggtgtccgcctcgtgctcggaggtcacccggtccgccggctgcggctgttgc
ccgatgtgcgccctgcctctgggcgccgcgtgcggcgtggcgactgcacgctgcgcccgg
ggactcagttgccgcgcgctgccgggggagcagcaacctctgcacgccctcacccgcggc
caaggcgcctgcgtgcaggagtctgacgcctccgctccccatgctgcagaggcagggagc
cctgaaagcccagagagcacggagataactgaggaggagctcctggataatttccatctg
atggccccttctgaagaggatcattccatcctttgggacgccatcagtacctatgatggc
tcgaaggctctccatgtcaccaacatcaaaaaatggaaggagccctgccgaatagaactc
tacagagtcgtagagagtttagccaaggcacaggagacatcaggagaagaaatttccaaa
ttttacctgccaaactgcaacaagaatggattttatcacagcagacagtgtgagacatcc
atggatggagaggcgggactctgctggtgcgtctacccttggaatgggaagaggatccct
gggtctccagagatcaggggagaccccaactgccagatatattttaatgtacaaaactga

KEGG   Homo sapiens (human): 3394
Entry
3394              CDS       T01001                                 
Symbol
IRF8, H-ICSBP, ICSBP, ICSBP1, IMD32A, IMD32B, IRF-8
Name
(RefSeq) interferon regulatory factor 8
  KO
K10155  interferon regulatory factor 8
Organism
hsa  Homo sapiens (human)
Pathway
hsa05133  Pertussis
Network
nt06310  CRH-ACTH-cortisol signaling
  Element
N00924  Glucocorticoid receptor signaling pathway
Disease
H00089  IFN-gamma/IL-12 axis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05133 Pertussis
    3394 (IRF8)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    3394 (IRF8)
Transcription factors [BR:hsa03000]
 Eukaryotic type
  Helix-turn-helix
   Tryptophan clusters interferon-regulating factors
    3394 (IRF8)
SSDB
Motif
Pfam: IRF-3 IRF MH2
Other DBs
NCBI-GeneID: 3394
NCBI-ProteinID: NP_002154
OMIM: 601565
HGNC: 5358
Ensembl: ENSG00000140968
Pharos: Q02556(Tbio)
UniProt: Q02556
LinkDB
Position
16:85899162..85922609
AA seq 426 aa
MCDRNGGRRLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAW
AVFKGKFKEGDKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRIVPEEEQKC
KLGVATAGCVNEVTEMECGRSEIDELIKEPSVDDYMGMIKRSPSPPEACRSQLLPDWWAQ
QPSTGVPLVTGYTTYDAHHSAFSQMVISFYYGGKLVGQATTTCPEGCRLSLSQPGLPGTK
LYGPEGLELVRFPPADAIPSERQRQVTRKLFGHLERGVLLHSSRQGVFVKRLCQGRVFCS
GNAVVCKGRPNKLERDEVVQVFDTSQFFRELQQFYNSQGRLPDGRVVLCFGEEFPDMAPL
RSKLILVQIEQLYVRQLAEEAGKSCGAGSVMQAPEEPPPDQVFRMFPDICASHQRSFFRE
NQQITV
NT seq 1281 nt   +upstreamnt  +downstreamnt
atgtgtgaccggaatggtggtcggcggcttcgacagtggctgatcgagcagattgacagt
agcatgtatccaggactgatttgggagaatgaggagaagagcatgttccggatcccttgg
aaacacgctggcaagcaagattataatcaggaagtggatgcctccatttttaaggcctgg
gcagtttttaaagggaagtttaaagaaggggacaaagctgaaccagccacttggaagacg
aggttacgctgtgctttgaataagagcccagattttgaggaagtgacggaccggtcccaa
ctggacatttccgagccatacaaagtttaccgaattgttcctgaggaagagcaaaaatgc
aaactaggcgtggcaactgctggctgcgtgaatgaagttacagagatggagtgcggtcgc
tctgaaatcgacgagctgatcaaggagccttctgtggacgattacatggggatgatcaaa
aggagcccttccccgccggaggcctgtcggagtcagctccttccagactggtgggcgcag
cagcccagcacaggcgtgccgctggtgacggggtacaccacctacgacgcgcaccattca
gcattctcccagatggtgatcagcttctactatgggggcaagctggtgggccaggccacc
accacctgccccgagggctgccgcctgtccctgagccagcctgggctgcccggcaccaag
ctgtatgggcccgagggcctggagctggtgcgcttcccgccggccgacgccatccccagc
gagcgacagaggcaggtgacgcggaagctgttcgggcacctggagcgcggggtgctgctg
cacagcagccggcagggcgtgttcgtcaagcggctgtgccagggccgcgtgttctgcagc
ggcaacgccgtggtgtgcaaaggcaggcccaacaagctggagcgtgatgaggtggtccag
gtcttcgacaccagccagttcttccgagagctgcagcagttctataacagccagggccgg
cttcctgacggcagggtggtgctgtgctttggggaagagtttccggatatggcccccttg
cgctccaaactcattctcgtgcagattgagcagctgtatgtccggcaactggcagaagag
gctgggaagagctgtggagccggctctgtgatgcaggcccccgaggagccgccgccagac
caggtcttccggatgtttccagatatttgtgcctcacaccagagatcatttttcagagaa
aaccaacagatcaccgtctaa

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