| Entry |
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| Symbol |
INPP4A, INPP4, TVAS1
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| Name |
(RefSeq) inositol polyphosphate-4-phosphatase type I A
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| KO |
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| Organism |
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| Pathway |
| hsa04070 | Phosphatidylinositol signaling system |
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| Module |
| hsa_M00131 | Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol |
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| Disease |
| H02994 | Neurodevelopmental disorder with growth impairment, quadriparesis, and poor or absent speech |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
3631 (INPP4A)
09130 Environmental Information Processing
09132 Signal transduction
04070 Phosphatidylinositol signaling system
3631 (INPP4A)
Enzymes [BR:hsa01000]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.66 phosphatidylinositol-3,4-bisphosphate 4-phosphatase
3631 (INPP4A)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
2:98444587..98594392
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| AA seq |
977 aa
MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL
DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY
DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR
PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG
NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT
IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI
GAPAAHCQGFKSGGLRKKLHKFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINT
LKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPD
YIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLEC
IIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKKGNPDSHAYWIRPEDPFCDVPSSPCPST
MPSTACHPHLTTHCSPPPEESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDS
APTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLS
TYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFD
ALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEV
LPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKD
RTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSEGCRRENTMKNVGSRKYAFNSLQLKA
FPKHYRPPEGTYGKVET |
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| NT seq |
2934 nt +upstreamnt +downstreamnt
atgacagcaagagagcacagccctcgccatggtgccagggcccgtgcaatgcagcgggct
tccaccatcgacgtggcggccgacatgctgggcctctctctggcaggaaatatacaagac
ccagatgagcccattttagaatttagcttagcttgcagtgagctgcatactccatcgcta
gatcgaaagccaaatagttttgttgcggtgagtgtcaccacccctcctcaggcattctgg
acgaagcatgcacagacggagatcattgagggaaccaacaatcctatatttctaagcagt
attgccttctttcaagactctcttatcaatcagatgacacaagtcaaactctccgtgtat
gatgtcaaagatagatctcagggaacaatgtatttactgggctctggaacgttcattgtc
aaagatctgctccaggacaggcatcataggttgcatttaacactaaggtctgcagagagt
gaccgtgtaggtaacatcaccgtgattggctggcagatggaggagaagtcagaccaacgg
ccccctgtgacccggtctgtggacactgtcaatgggaggatggttcttcctgtcgatgag
agcttgacggaggcgttaggaatccgatccaaatacgcttcattgcgaaaggacactttg
ctgaaatcggtgttcggtggtgccatctgccgcatgtaccggtttccaaccactgatggt
aaccatttgcggatcctggagcagatggcagagagcgtgctctccctgcacgtgccccgg
cagttcgtgaagctcctactagaggaagatgcagccagagtgtgtgagctggaggagctg
ggagagctgtccccttgctgggagagcctccggcgccaaattgtcacccagtaccagacc
atcatcctcacataccaggagaacctgaccgacctccatcagtacagagggccctcgttt
aaagcaagcagtttgaaagcagataaaaagttagaatttgttcccacaaacttgcacata
caaaggatgagagttcaagacgatggaggatcagatcagaactacgacatcgtcaccatt
ggggcgccagcagcacactgccaaggttttaagtcaggaggtctccgcaaaaagctgcac
aaatttgaagagaccaagaaacattttgaggagtgttgtacatcatctggctgccagtcc
ataatctacataccccaggatgttgtcagagccaaggagatcatcgcccagatcaacacc
ctgaaaacccaagtgagttactacgcagagcggctgtcaagggcagccaaggacaggtct
gccactggccttgagaggacactcgccatcttggcagacaagacacggcagctggtcacg
gtctgcgactgcaagctcctggccaactccatccatgggctgaacgctgcacggcctgac
tacattgcctccaaggcctctcccacttcgactgaggaggagcaggtgatgcttagaaat
gaccaggacaccctcatggcccggtggacagggagaaacagccgatcttccctgcaggtg
gactggcacgaggaggagtgggagaaagtgtggctgaacgtggacaagagcctagagtgc
atcattcagcgtgtggacaagctgctgcagaaggagcggctgcatggcgagggctgtgag
gatgtcttcccctgtgcaggcagctgcaccagcaagaaaggtaacccggacagccacgcc
tactggatcagaccagaagaccccttctgtgatgtcccctcctcaccatgcccctccacc
atgccctccactgcatgccatcctcatctgaccacacattgcagtccccctcctgaagag
tccagcccaggtgaatggagtgaggccctttacccgctgctgaccactctcaccgactgc
gtggccatgatgagtgacaaggccaagaaggccatggtattcctgctcatgcaggacagc
gcgcccaccatagccacctacctgagcctgcagtaccgccgtgacgtggtcttctgccag
acgctgaccgccctcatctgcggcttcatcattaagctgaggaactgcctgcatgacgac
ggcttcctgcgccagctctacaccatcgggctgctggcccagttcgagagcctgctgagc
acctacggggaggagctggcaatgctggaggacatgagccttgggatcatggacttgagg
aacgtgaccttcaaagtcactcaggccacttccagcgcctccgcagacatgctgcccgtc
atcacaggaaatcgcgacgggtttaacgtgcgggtccctctgccgggcccgctgtttgac
gccttgccccgggagatccagagtggcatgctgctgcgagtgcagcccgtcctcttcaac
gtgggcatcaatgagcagcagacactggccgagaggtttggcgatacgtctttacaagaa
gtcatcaacgtggagagtttggtgcggttaaattcctactttgagcagtttaaggaagtt
ttgcctgaggattgcctgcctcggtctcgcagtcagacgtgcctgccagagctgctgcgg
tttctgggtcagaacgtgcatgcccggaagaataagaacgtcgacattctctggcaagct
gctgagatctgccgccgccttaatggggtccggttcaccagctgcaagagcgctaaggac
cgtacagccatgtcggtgacactggagcagtgcctgatcctgcaacacgagcatggcatg
gccccgcaggtcttcacccaggccctggagtgcatgcgcagtgagggttgtcgaagagaa
aatacaatgaagaatgttggaagtcgcaaatatgcatttaattccctgcagctgaaggct
ttccccaagcattacaggcctcccgaagggacttacggaaaagttgaaacgtga |
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