Homo sapiens (human): 3633
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Entry
3633 CDS
T01001
Symbol
INPP5B, 5PTase
Name
(RefSeq) type II inositol 1,4,5-trisphosphate 5-phosphatase isoform 2 precursor
KO
K01099
inositol polyphosphate 5-phosphatase INPP5B/F [EC:
3.1.3.36
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00562
Inositol phosphate metabolism
hsa01100
Metabolic pathways
hsa04070
Phosphatidylinositol signaling system
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
3633 (INPP5B)
09130 Environmental Information Processing
09132 Signal transduction
04070 Phosphatidylinositol signaling system
3633 (INPP5B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
3633 (INPP5B)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.36 phosphoinositide 5-phosphatase
3633 (INPP5B)
Membrane trafficking [BR:
hsa04131
]
Exocytosis
Small GTPases and associated proteins
Rab associated proteins
3633 (INPP5B)
Endocytosis
Clathrin-mediated endocytosis
Inositol 5-phosphatases
3633 (INPP5B)
Rab GTPases and associated proteins
Rab associated proteins
3633 (INPP5B)
Protein recycling
Other Rab GTPase associated proteins
3633 (INPP5B)
Endosome - Golgi transport
Rab associated proteins
3633 (INPP5B)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Exo_endo_phos2
OCRL-like_ASH
RhoGAP
Exo_endo_phos
Ubiquitin_IARS1
Motif
Other DBs
NCBI-GeneID:
3633
NCBI-ProteinID:
NP_001284363
OMIM:
147264
HGNC:
6077
UniProt:
P32019
B3KMW4
Structure
PDB
PDBj
LinkDB
All DBs
Position
1:complement(37860697..37947057)
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AA seq
749 aa
AA seq
DB search
MSAAAGSRERNTAGGSNFDGLRPNGKGVPMDQSSRGQDKPESLQPRQNKSKSEITDMVRS
STITVSDKAHILSMQKFGLRDTIVKSHLLQKEEDYTYIQNFRFFAGTYNVNGQSPKECLR
LWLSNGIQAPDVYCVGFQELDLSKEAFFFHDTPKEEEWFKAVSEGLHPDAKYAKVKLIRL
VGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAH
IEEYERRNQDYKDICSRMQFCQPDPSLPPLTISNHDVILWLGDLNYRIEELDVEKVKKLI
EEKDFQMLYAYDQLKIQVAAKTVFEGFTEGELTFQPTYKYDTGSDDWDTSEKCRAPAWCD
RILWKGKNITQLSYQSHMALKTSDHKPVSSVFDIGVRVVNDELYRKTLEEIVRSLDKMEN
ANIPSVSLSKREFCFQNVKYMQLKVESFTIHNGQVPCHFEFINKPDEESYCKQWLNANPS
RGFLLPDSDVEIDLELFVNKMTATKLNSGEDKIEDILVLHLDRGKDYFLSVSGNYLPSCF
GSPIHTLCYMREPILDLPLETISELTLMPVWTGDDGSQLDSPMEIPKELWMMVDYLYRNA
VQQEDLFQQPGLRSEFEHIRDCLDTGMIDNLSASNHSVAEALLLFLESLPEPVICYSTYH
NCLECSGNYTASKQVISTLPIFHKNVFHYLMAFLRELLKNSAKNHLDENILASIFGSLLL
RNPAGHQKLDMTEKKKAQEFIHQFLCNPL
NT seq
2250 nt
NT seq
+upstream
nt +downstream
nt
atgtctgccgccgccggctctcgggagcgcaacactgcaggtggttctaactttgatggt
ttgagaccaaatgggaagggagtgcctatggaccaaagctccaggggtcaagataaacca
gaaagcttgcaaccaagacagaataaatccaagtccgaaattactgacatggttcgctcc
tccactatcacagtgtcggacaaggctcatattttatccatgcagaagtttggactgcga
gatacaattgtgaaatcacatctactacagaaagaagaggattacacctatatccagaac
ttcaggttttttgcgggaacatacaatgtaaatgggcagtcccccaaagaatgcctccgg
ctgtggctgagcaatggtatccaggccccagatgtctattgtgtagggttccaggagctt
gatctgagtaaggaagcttttttctttcacgataccccaaaggaggaagagtggttcaaa
gctgtgtcagagggtcttcatccagatgccaaatatgcaaaggtgaagcttatccgactg
gttgggattatgctgctgttatatgtcaaacaggagcatgcagcttatatctcagaagtg
gaagccgagactgtggggacaggaatcatggggaggatgggcaacaagggaggcgtggcg
atcaggttccagttccacaacaccagcatctgcgttgtgaattctcacttggcagcccac
attgaagagtatgagaggaggaaccaggactataaggacatttgttctcgaatgcagttt
tgtcagcctgacccaagccttccccctctcaccatcagcaaccatgatgtgatcttgtgg
ctgggggacctcaactacaggatagaagagctggatgtggaaaaagtgaaaaagctcatc
gaagagaaggactttcaaatgctgtatgcatatgatcagctgaaaattcaggtggccgca
aagactgtctttgaaggcttcacagagggtgagctcacattccagcctacttacaagtat
gatacgggctctgacgactgggataccagtgagaagtgccgtgctcctgcctggtgtgat
cggattctctggaaagggaagaacatcactcagctgagttaccagagccacatggccctg
aagaccagtgaccacaagcctgtcagctcagtgtttgacatcggggtgagggtcgtaaat
gacgagctttaccggaagacactggaggaaattgttcgctccctggataagatggaaaat
gccaacattccttctgtgtccctgtccaagcgagagttctgttttcagaatgtgaagtac
atgcaattgaaagtagaatcctttacaattcataatggacaagtaccctgtcattttgaa
ttcatcaacaagcctgatgaagagtcttactgtaagcagtggctgaatgccaaccccagc
agaggcttcctcctgccagattctgatgttgagattgacttggagctcttcgtaaataag
atgacagctacaaagctcaactcgggtgaagacaaaattgaggacattctggttctgcac
ttggacaggggaaaggattactttttgtctgtgtctgggaactacctgcccagctgtttt
gggtctcccattcatacactgtgttacatgagagagccaatcttggacctaccacttgaa
accattagtgagctgactctgatgccagtatggactggagatgatgggagccagttggat
agccccatggaaatccccaaagagctctggatgatggttgattacctgtaccgaaatgct
gtccagcaggaagatctgtttcagcaaccaggcctgaggtcagaatttgaacatatcagg
gactgcttggatactggaatgattgataacctctctgccagcaatcattctgtagccgaa
gccctgctgcttttcctggagagccttccagagcctgtcatctgttacagcacctaccat
aactgcttggagtgttctggcaactacacagcaagcaaacaggtcatttctactctcccc
atattccacaaaaatgtcttccactacttgatggcgtttttgcgagaactgctgaaaaat
tcagcaaaaaatcatttggatgagaatattctagctagcatatttggcagcttattgctt
cgaaacccagctggtcaccaaaagcttgatatgacagagaagaagaaggctcaagaattt
attcaccagttcctctgcaacccactctga
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