Homo sapiens (human): 3645
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Entry
3645 CDS
T01001
Symbol
INSRR, IRR
Name
(RefSeq) insulin receptor related receptor
KO
K05086
insulin receptor-related receptor [EC:
2.7.10.1
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04810
Regulation of actin cytoskeleton
hsa05215
Prostate cancer
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
3645 (INSRR)
09160 Human Diseases
09162 Cancer: specific types
05215 Prostate cancer
3645 (INSRR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
3645 (INSRR)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
3645 (INSRR)
Protein kinases [BR:
hsa01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
3645 (INSRR)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Pkinase
Furin-like
fn3
Kinase-like
Motif
Other DBs
NCBI-GeneID:
3645
NCBI-ProteinID:
NP_055030
OMIM:
147671
HGNC:
6093
Ensembl:
ENSG00000027644
UniProt:
P14616
Structure
PDB
PDBj
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All DBs
Position
1:complement(156840063..156859117)
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AA seq
1297 aa
AA seq
DB search
MAVPSLWPWGACLPVIFLSLGFGLDTVEVCPSLDIRSEVAELRQLENCSVVEGHLQILLM
FTATGEDFRGLSFPRLTQVTDYLLLFRVYGLESLRDLFPNLAVIRGTRLFLGYALVIFEM
PHLRDVALPALGAVLRGAVRVEKNQELCHLSTIDWGLLQPAPGANHIVGNKLGEECADVC
PGVLGAAGEPCAKTTFSGHTDYRCWTSSHCQRVCPCPHGMACTARGECCHTECLGGCSQP
EDPRACVACRHLYFQGACLWACPPGTYQYESWRCVTAERCASLHSVPGRASTFGIHQGSC
LAQCPSGFTRNSSSIFCHKCEGLCPKECKVGTKTIDSIQAAQDLVGCTHVEGSLILNLRQ
GYNLEPQLQHSLGLVETITGFLKIKHSFALVSLGFFKNLKLIRGDAMVDGNYTLYVLDNQ
NLQQLGSWVAAGLTIPVGKIYFAFNPRLCLEHIYRLEEVTGTRGRQNKAEINPRTNGDRA
ACQTRTLRFVSNVTEADRILLRWERYEPLEARDLLSFIVYYKESPFQNATEHVGPDACGT
QSWNLLDVELPLSRTQEPGVTLASLKPWTQYAVFVRAITLTTEEDSPHQGAQSPIVYLRT
LPAAPTVPQDVISTSNSSSHLLVRWKPPTQRNGNLTYYLVLWQRLAEDGDLYLNDYCHRG
LRLPTSNNDPRFDGEDGDPEAEMESDCCPCQHPPPGQVLPPLEAQEASFQKKFENFLHNA
ITIPISPWKVTSINKSPQRDSGRHRRAAGPLRLGGNSSDFEIQEDKVPRERAVLSGLRHF
TEYRIDIHACNHAAHTVGCSAATFVFARTMPHREADGIPGKVAWEASSKNSVLLRWLEPP
DPNGLILKYEIKYRRLGEEATVLCVSRLRYAKFGGVHLALLPPGNYSARVRATSLAGNGS
WTDSVAFYILGPEEEDAGGLHVLLTATPVGLTLLIVLAALGFFYGKKRNRTLYASVNPEY
FSASDMYVPDEWEVPREQISIIRELGQGSFGMVYEGLARGLEAGEESTPVALKTVNELAS
PRECIEFLKEASVMKAFKCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSHLRSLRPEAEN
NPGLPQPALGEMIQMAGEIADGMAYLAANKFVHRDLAARNCMVSQDFTVKIGDFGMTRDV
YETDYYRKGGKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQGLSNEQ
VLKFVMDGGVLEELEGCPLQLQELMSRCWQPNPRLRPSFTHILDSIQEELRPSFRLLSFY
YSPECRGARGSLPTTDAEPDSSPTPRDCSPQNGGPGH
NT seq
3894 nt
NT seq
+upstream
nt +downstream
nt
atggcagtgcctagtctgtggccctggggagcatgcctgcctgtgatcttcctctccttg
ggatttggcctggatacagtagaggtgtgccccagcctggatattcgctcagaggtggca
gagcttcgtcagctggagaactgcagcgtggtggagggccacctgcagatcctgctcatg
ttcacagccaccggggaggacttccgcggcctcagcttccctcgcctcacccaggtcacc
gactacctgctgctcttccgtgtctacggactggagagcctgcgcgacctcttccccaac
ctagcagtcatccgcgggacgcgcctcttcctgggctatgcactggtcatctttgagatg
ccacatctgcgtgacgtggcactgcctgcacttggggccgtgctgcgtggggctgtgcgt
gtggagaagaaccaggagctctgccacctctccaccattgactggggactgctgcagcca
gcacctggcgccaaccacatcgtgggcaacaagctgggcgaggagtgtgctgacgtgtgc
cctggtgtgctgggtgctgctggtgagccctgtgccaagaccaccttcagcgggcacact
gactacagatgctggacctccagccactgccagagagtgtgcccctgcccccatgggatg
gcttgcacagcgaggggcgagtgctgccacaccgaatgcctggggggctgcagccagcca
gaagaccctcgtgcctgtgtagcttgccgccacctctacttccagggtgcctgcctgtgg
gcctgcccgccaggcacctaccagtatgagtcctggcgctgtgtcacagctgagcgctgt
gccagcctgcactctgtgcccggccgtgcctccaccttcggcatacaccagggcagttgc
ctggcccagtgcccttctggcttcacccgtaatagcagcagcatattctgccacaagtgc
gaggggctgtgccctaaagagtgcaaggtaggcaccaagaccatcgactccatccaggcg
gcacaggatcttgtgggctgcacgcatgtggagggaagcctcatcctcaaccttcgccag
ggctacaacctggagccacagctgcagcacagcctggggctggtagaaaccattactggc
ttcctcaaaatcaagcactcctttgccctcgtgtccctgggctttttcaagaacctcaaa
ctaatccggggagacgccatggtggatgggaactacactctctacgtgctggacaaccag
aacctacaacagctagggtcctgggtggccgcggggctcaccattcccgtgggcaagatc
tacttcgccttcaacccgcgcctctgcttggaacacatctaccgactggaggaggtgaca
ggcacgcgaggtcggcagaacaaggctgagatcaacccccgcaccaacggagaccgcgcc
gcctgccagactcgcaccctgcgcttcgtgtccaacgtgacggaggcagaccgcatcctg
ctacgctgggagcgctatgagccactggaggcccgcgacctgctcagcttcatcgtgtac
tacaaggagtccccattccagaacgccacagagcacgtgggtccagatgcttgtggaacc
cagagctggaacctgctggatgtggagctgcccctaagccgcacccaggagccaggggtg
accctagcctccctcaagccttggacacagtacgcagtgtttgtgcgggccatcacgcta
accactgaggaggacagccctcatcaaggagcccagagtcccatcgtctacctccgaacg
ctgcctgcagctcccacggtgccccaagacgtcatctccacgtccaactcctcctcccac
ctcctggtgcgctggaagccaccgacccagcgcaatgggaacctcacctactacctggtg
ctgtggcagcggctggcagaggacggcgacctctacctcaatgactactgccaccgcggc
ttgcggctgcccaccagcaacaacgatccgcgcttcgacggcgaagacggggatcctgag
gccgagatggagtccgactgctgcccttgccagcacccacctcctggtcaggttctgccc
ccgctggaggcgcaagaggcctcgttccagaagaagtttgaaaactttctacacaacgcg
atcaccatccccatatccccttggaaggtgacgtccatcaacaagagcccccaaagggac
tcagggcggcaccgccgggcagctgggcccctccggctggggggcaacagctcggatttc
gagatccaggaggacaaggtgccccgtgagcgagcggtgctgagcggcctgcgccacttc
acggaataccggatcgacatccatgcctgcaaccacgcggcgcacaccgtgggctgcagc
gccgccaccttcgtctttgcgcgcaccatgccccacagagaggctgatggtattccagga
aaggtggcctgggaggcctccagcaagaacagtgtccttctgcgctggctcgagccacca
gaccccaacggactcatcctcaagtacgaaatcaagtaccgccgcttgggagaggaggcc
acagtgctgtgtgtgtcccgtcttcgatatgcgaagtttgggggagtccacctggccctg
ctgccccctggaaactactctgccagggttagggcaacctcactggctggcaatggctct
tggacagacagtgttgccttctacatccttggcccagaggaggaggatgctggggggctg
catgtcctcctcactgccacccctgtggggctcacgctgctcatcgttcttgctgccctt
ggtttcttctacggcaagaagagaaacagaaccctgtatgcttctgtgaatccagagtac
ttcagcgcctctgatatgtatgtccctgatgaatgggaggtgcctcgggagcagatctcg
ataatccgggaactgggccagggctcttttgggatggtatatgaggggctggcacgagga
cttgaggctggagaggagtccacacccgtggccctgaagacggtgaatgagctggccagc
ccacgggaatgcattgagttcctcaaggaagcttctgtcatgaaagccttcaagtgtcac
catgtggtgcgtctcctgggtgtggtatctcagggccagccaactctggtcatcatggag
ttaatgacccgtggggacctcaagagccatcttcgatctttgcggcctgaggcagagaac
aaccctgggctcccacagccagcattgggggaaatgatccaaatggctggtgagattgca
gacggcatggcctaccttgctgccaacaagtttgtgcaccgagatctagcagcccgcaac
tgcatggtgtcccaggacttcaccgtcaagatcggggacttcgggatgactcgggacgtg
tatgagacagactattaccgcaagggtgggaaggggctgctgcccgtgcgctggatggcc
cccgagtccctcaaagatgggatcttcaccacccactcggatgtctggtcctttggcgtg
gtactctgggagattgtgaccctggcagaacaaccctaccagggcctgtccaatgagcag
gtgctgaagttcgtcatggatggcggggtcctggaggagctggagggctgtccccttcag
ctgcaggagctgatgagccgctgctggcagccgaacccacgcctgcgcccatctttcaca
cacattctggacagcatacaggaggagctgcggccctccttccgcctcctctccttctac
tacagcccggaatgccggggggcccggggctccctgcctaccaccgatgcagagcctgac
tcctcacccactccaagagactgcagccctcaaaatgggggtccagggcactga
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integrated database retrieval system
