| Entry |
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| Symbol |
PTPRQ, DFNA73, DFNB84, DFNB84A, PTPGMC1, R-PTP-Q
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| Name |
(RefSeq) protein tyrosine phosphatase receptor type Q
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| KO |
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| Organism |
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| Disease |
| H00604 | Deafness, autosomal dominant |
| H00605 | Deafness, autosomal recessive |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:hsa01009]
374462 (PTPRQ)
09183 Protein families: signaling and cellular processes
03037 Cilium and associated proteins [BR:hsa03037]
374462 (PTPRQ)
Enzymes [BR:hsa01000]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
374462 (PTPRQ)
Protein phosphatases and associated proteins [BR:hsa01009]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Receptor PTPs
374462 (PTPRQ)
Cilium and associated proteins [BR:hsa03037]
Other cilia and associated proteins
Stereociliary proteins
374462 (PTPRQ)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
12:80444235..80680273
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| AA seq |
2299 aa
MDFLIIFLLLFIGTSETQVDVSNVVPGTRYDITISSISTTYTSPVTRIVTTNVTKPGPPV
FLAGERVGSAGILLSWNTPPNPNGRIISYIVKYKEVCPWMQTVYTQVRSKPDSLEVLLTN
LNPGTTYEIKVAAENSAGIGVFSDPFLFQTAESAPGKVVNLTVEAYNASAVKLIWYLPRQ
PNGKITSFKISVKHARSGIVVKDVSIRVEDILTGKLPECNENSESFLWSTASPSPTLGRV
TPPSRTTHSSSTLTQNEISSVWKEPISFVVTHLRPYTTYLFEVSAATTEAGYIDSTIVRT
PESVPEGPPQNCVTGNITGKSFSILWDPPTIVTGKFSYRVELYGPSGRILDNSTKDLKFA
FTNLTPFTMYDVYIAAETSAGTGPKSNISVFTPPDVPGAVFDLQLAEVESTQVRITWKKP
RQPNGIINQYRVKVLVPETGIILENTLLTGNNEYINDPMAPEIVNIVEPMVGLYEGSAEM
SSDLHSLATFIYNSHPDKNFPARNRAEDQTSPVVTTRNQYITDIAAEQLSYVIRRLVPFT
EHMISVSAFTIMGEGPPTVLSVRTRQQVPSSIKIINYKNISSSSILLYWDPPEYPNGKIT
HYTIYAMELDTNRAFQITTIDNSFLITGLKKYTKYKMRVAASTHVGESSLSEENDIFVRT
SEDEPESSPQDVEVIDVTADEIRLKWSPPEKPNGIIIAYEVLYKNIDTLYMKNTSTTDII
LRNLRPHTLYNISVRSYTRFGHGNQVSSLLSVRTSETVPDSAPENITYKNISSGEIELSF
LPPSSPNGIIQKYTIYLKRSNGNEERTINTTSLTQNIKVLKKYTQYIIEVSASTLKGEGV
RSAPISILTEEDAPDSPPQDFSVKQLSGVTVKLSWQPPLEPNGIILYYTVYVWNRSSLKT
INVTETSLELSDLDYNVEYSAYVTASTRFGDGKTRSNIISFQTPEGAPSDPPKDVYYANL
SSSSIILFWTPPSKPNGIIQYYSVYYRNTSGTFMQNFTLHEVTNDFDNMTVSTIIDKLTI
FSYYTFWLTASTSVGNGNKSSDIIEVYTDQDIPEGFVGNLTYESISSTAINVSWVPPAQP
NGLVFYYVSLILQQTPRHVRPPLVTYERSIYFDNLEKYTDYILKITPSTEKGFSDTYTAQ
LYIKTEEDVPETSPIINTFKNLSSTSVLLSWDPPVKPNGAIISYDLTLQGPNENYSFITS
DNYIILEELSPFTLYSFFAAARTRKGLGPSSILFFYTDESVPLAPPQNLTLINCTSDFVW
LKWSPSPLPGGIVKVYSFKIHEHETDTIYYKNISGFKTEAKLVGLEPVSTYSIRVSAFTK
VGNGNQFSNVVKFTTQESVPDVVQNMQCMATSWQSVLVKWDPPKKANGIITQYMVTVERN
STKVSPQDHMYTFIKLLANTSYVFKVRASTSAGEGDESTCHVSTLPETVPSVPTNIAFSD
VQSTSATLTWIRPDTILGYFQNYKITTQLRAQKCKEWESEECVEYQKIQYLYEAHLTEET
VYGLKKFRWYRFQVAASTNAGYGNASNWISTKTLPGPPDGPPENVHVVATSPFSISISWS
EPAVITGPTCYLIDVKSVDNDEFNISFIKSNEENKTIEIKDLEIFTRYSVVITAFTGNIS
AAYVEGKSSAEMIVTTLESAPKDPPNNMTFQKIPDEVTKFQLTFLPPSQPNGNIQVYQAL
VYREDDPTAVQIHNLSIIQKTNTFVIAMLEGLKGGHTYNISVYAVNSAGAGPKVPMRITM
DIKAPARPKTKPTPIYDATGKLLVTSTTITIRMPICYYSDDHGPIKNVQVLVTETGAQHD
GNVTKWYDAYFNKARPYFTNEGFPNPPCTEGKTKFSGNEEIYIIGADNACMIPGNEDKIC
NGPLKPKKQYLFKFRATNIMGQFTDSDYSDPVKTLGEGLSERTVEIILSVTLCILSIILL
GTAIFAFARIRQKQKEGGTYSPQDAEIIDTKLKLDQLITVADLELKDERLTRLLSYRKSI
KPISKKSFLQHVEELCTNNNLKFQEEFSELPKFLQDLSSTDADLPWNRAKNRFPNIKPYN
NNRVKLIADASVPGSDYINASYISGYLCPNEFIATQGPLPGTVGDFWRMVWETRAKTLVM
LTQCFEKGRIRCHQYWPEDNKPVTVFGDIVITKLMEDVQIDWTIRDLKIERHGDCMTVRQ
CNFTAWPEHGVPENSAPLIHFVKLVRASRAHDTTPMIVHCSAGVGRTGVFIALDHLTQHI
NDHDFVDIYGLVAELRSERMCMVQNLAQYIFLHQCILDLLSNKGSNQPICFVNYSALQKM
DSLDAMEGDVELEWEETTM |
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| NT seq |
6900 nt +upstreamnt +downstreamnt
atggattttcttatcatttttcttttactttttattgggacttcagagacacaggttgat
gtttccaatgtcgttcctggtactaggtacgatataaccatctcttcaatttctacaaca
tacacctcacctgttactagaatagtgacaacaaatgtaacaaaaccagggcctccagtc
ttcctagccggggaaagagtcggatctgctgggattcttctgtcttggaatacaccacct
aatccaaatggaaggattatatcttacattgtcaaatataaggaagtttgtccgtggatg
caaacagtatatacacaagtcagatcaaagccagacagtctggaagttcttcttactaat
cttaatcctggaacaacatatgaaattaaggttgctgctgaaaacagtgctggcattgga
gtgtttagtgatccatttctcttccaaactgcagaaagtgctccaggaaaagtggtgaat
ctcacagttgaggcctacaacgcttcagcagttaagctgatttggtatttacctcggcaa
ccaaatggcaaaattaccagcttcaagattagtgtcaagcatgccagaagtgggatagta
gtgaaagatgtctcaatcagagtagaggacattttgactgggaaattgccagaatgcaat
gagaatagtgaatcttttttatggagtacagccagcccttctccaacccttggtagagtt
acacctccatcgcgtaccacacattcatcaagcacgttgacacagaatgagatcagctct
gtgtggaaagagcctatcagttttgtagtgacacacttgagaccttatacaacatatctt
tttgaagtttcagctgctacaactgaagcaggttatattgatagtacgattgtcagaaca
ccagaatcagtgcctgaaggaccaccacaaaactgcgtaacaggcaacatcacaggaaag
tccttttcaattttatgggacccaccaactatagtaacagggaaatttagttatagagtt
gaattatatggaccatcaggtcgcattttggataacagcacaaaagacctcaagtttgca
ttcactaacctaacaccatttacaatgtatgatgtctatattgcggctgaaaccagtgca
gggactgggcccaagtcaaatatttcagtattcactccaccagatgttccaggggcagtg
tttgatttacaacttgcagaggtagaatccacgcaagtaagaattacttggaagaaacca
cgacaaccaaatggaattattaaccaataccgagtgaaagtgctagttccagagacagga
ataattttggaaaatactttgctcactggaaataatgagtatataaatgaccccatggct
ccagaaattgtgaacatagtagagccaatggtaggattatatgagggttcagcagagatg
tcgtctgaccttcactcacttgctacatttatatataacagccatccagataaaaacttt
cctgcaaggaatagagctgaagaccagacttcaccagttgtaactacaaggaatcagtat
attactgacattgcagctgaacagctgtcttatgttatcaggagacttgtacctttcact
gagcacatgattagtgtatctgctttcaccatcatgggagaaggaccaccaacagttctc
agtgttaggacacgtcagcaagtgccaagctccattaaaattataaactataaaaatatt
agttcttcatctattttgttatattgggatcctccagaatatcccaatggaaaaataact
cactatacgatttatgcaatggaattggatacaaacagagcattccagataactaccata
gataacagctttctcataacagggttaaagaaatacacaaaatacaaaatgagagtggca
gcctcaacccacgttggagaaagttctttgtctgaagaaaatgacatctttgtgagaact
tcagaagatgaaccggaatcatcacctcaagatgtcgaagtaattgatgttaccgcagat
gaaataaggttgaagtggtcaccacccgaaaagcccaatgggatcattattgcttatgaa
gtgctatataaaaatatagatactttatatatgaagaacacatcaacaacagacataata
ttaaggaacttaagacctcacaccctctataacatttctgtaaggtcttacaccagattt
ggtcatggcaatcaggtatcttctttactctctgtaaggacttcggagactgtgcctgat
agtgcaccagaaaatatcacttacaaaaatatttcttctggagagattgagctatcattc
cttcccccaagtagtcccaatggaatcatacaaaaatatacaatttatctcaagagaagt
aatggaaatgaggaaagaactataaatacaacctctttaacccaaaacattaaagtactg
aagaaatatacccaatatatcattgaggtgtctgctagtacactcaaaggtgaaggagtt
cggagtgctcccataagtatactgacggaggaagatgctcctgattctccccctcaagac
ttctctgtaaaacagttgtctggtgtcacggtgaagttgtcatggcaaccacccctggag
ccaaatggaattatcctttattacacagtttatgtctggaatagatcatcattaaaaact
attaatgtcactgaaacatcattggagttatcagatttggattataatgttgaatacagt
gcttatgtaacagctagcaccagatttggtgatgggaaaacaagaagcaatatcattagc
tttcaaacaccagagggagcaccaagcgatcctcccaaagatgtttattatgcaaacctc
agttcttcatcaataattcttttctggacacctccttcaaaacctaatgggattatacaa
tattactctgtttattacagaaatacttcaggtacttttatgcagaattttacactccat
gaagtaaccaatgactttgacaatatgactgtatccacaattatagataaactgacaata
ttcagctactatacattttggttaacagcaagtacttcagttggaaatgggaataaaagc
agtgacatcattgaagtatacacagatcaagacatacctgaagggtttgttggaaacctg
acttacgaatccatttcgtcaactgcaataaatgtaagctgggtcccaccggctcaacca
aacggtctagtcttctactatgtttcactgatcttacagcagactcctcgccatgtgaga
ccacctcttgttacatatgagagaagcatatattttgataatctggaaaaatacactgat
tatatattaaaaattactccatcaacagaaaagggattctctgatacctatactgcccag
ctatacatcaagactgaagaagatgtcccagaaacttcaccaataatcaacacttttaaa
aacctttcctctacctcagttctcttatcatgggatcccccagtaaagccaaatggtgca
ataataagttatgatttaactttacaaggaccaaatgaaaattattctttcattacttct
gataattacataatattggaagagctttcaccatttacattatatagcttttttgctgcc
gcaagaactagaaaaggacttggtccttccagtattcttttcttttacacagatgagtca
gtgccgttagcacctccacaaaatttgactttaatcaactgtacttcagactttgtatgg
ctgaaatggagcccaagtcctcttccaggtggtattgttaaagtatatagttttaaaatt
catgaacatgaaactgacactatatattataagaatatatcaggatttaaaactgaagcc
aaacttgttggactggaaccagtcagcacctactctatccgtgtatctgcgttcaccaaa
gttggaaatggcaatcaatttagtaatgtagtaaaattcacaacccaagaatcagttcca
gatgtcgtgcagaatatgcagtgcatggcaactagctggcagtcagttttagtgaaatgg
gatccacccaaaaaggcaaatggaataataacgcagtatatggtaacagttgaaaggaat
tctacaaaagtttctccccaagatcacatgtacactttcataaagcttcttgccaatacc
tcatatgtctttaaagtaagagcttcaacctcagctggtgaaggtgatgaaagcacatgc
catgtcagcacactacctgaaacagttcccagtgttcccacaaatattgctttttctgat
gttcagtcaactagtgcaacattgacatggataagacctgacactatccttggctacttt
caaaattacaaaattaccactcaacttcgtgctcaaaaatgcaaagaatgggaatccgaa
gaatgtgttgaatatcaaaaaattcaatacctctatgaagctcacttaactgaagagaca
gtatatggattaaagaaatttagatggtatagattccaagtggctgccagcaccaatgct
ggctatggcaatgcttcaaactggatttctacaaaaactctgcctggccctccagatggt
cctcctgaaaatgttcatgtagtagcaacatcaccttttagcatcagcataagctggagt
gaacctgctgtcattactggaccaacatgttatctgattgatgtcaaatcggtagataat
gatgaatttaatatatccttcatcaagtcaaatgaagaaaataaaaccatagaaattaaa
gatttagaaatattcacaaggtattctgtagtgatcactgcatttactgggaacattagt
gctgcatatgtagaagggaagtcaagtgctgaaatgattgttactactttagaatcagcc
ccaaaggacccacctaacaacatgacatttcagaagataccagatgaagttacaaaattt
caattaacgttccttcctccttctcaacctaatggaaatatccaagtatatcaagctctg
gtttaccgagaagatgatcctactgctgtccagattcacaacctcagtattatacagaaa
accaacacattcgtcattgcaatgctagaaggactaaaaggtggacatacatacaatatc
agtgtttacgcagtcaatagtgctggtgcaggtccaaaggttccgatgagaataaccatg
gatatcaaagctccagcacgaccaaaaaccaaaccaacccctatttatgatgccacagga
aaactgcttgtgacttcaacaacaattacaatcagaatgccaatatgttactacagtgat
gatcatggaccaataaaaaatgtacaagtgcttgtgacagaaacaggagctcagcatgat
ggaaatgtaacaaagtggtatgatgcatattttaataaagcaaggccatattttacaaat
gaaggctttcctaaccctccatgtacagaaggaaagacaaagtttagtggcaatgaagaa
atctacatcataggtgctgataatgcatgcatgattcctggcaatgaagacaaaatttgc
aatggaccactgaaaccaaaaaagcaatacttatttaaatttagagctacaaatattatg
ggacaatttactgactctgattattctgaccctgttaagactttaggggaaggactttca
gaaagaaccgtagagatcattctttccgtcactttgtgtatcctttcaataattctcctt
ggaacagctatttttgcatttgcaagaattcgacagaagcagaaagaaggtggcacatac
tctcctcaggatgcagaaattattgacactaaattgaagctggatcagctcatcacagtg
gcagacctggaactgaaggacgagagattaacgcggttacttagttatagaaaatccatc
aagccaataagcaagaaatccttcctgcaacatgttgaagagctttgcacaaacaacaac
ctaaagtttcaagaagaattttcggaattaccaaaatttcttcaggatctttcttcaact
gatgctgatctgccttggaatagagcaaaaaaccgcttcccaaacataaaaccatataat
aataacagagtaaagctgatagctgacgctagtgttccaggttcggattatattaatgcc
agctatatttctggttatttatgtccaaatgaatttattgctactcaaggtccactacca
ggaacagttggagatttttggagaatggtgtgggaaaccagagcaaaaacattagtaatg
ctaacacagtgttttgaaaaaggacggatcagatgccatcagtattggccagaggacaac
aagccagttactgtctttggagatatagtgattacaaagctaatggaggatgttcaaata
gattggactatcagggatctgaaaattgaaaggcatggggattgcatgactgttcgacag
tgtaactttactgcctggccagagcatggggttcctgagaacagcgcccctctaattcac
tttgtgaagttggttcgagcaagcagggcacatgacaccacacctatgattgttcactgc
agtgctggagttggaagaactggagtttttattgctctggaccatttaacacaacatata
aatgaccatgattttgtggatatatatggactagtagctgaactgagaagtgaaagaatg
tgcatggtgcagaatctggcacagtatatctttttacaccagtgcattctggatctctta
tcaaataagggaagtaatcagcccatctgttttgttaactattcagcacttcagaagatg
gactctttggacgccatggaaggtgatgttgagcttgaatgggaagaaaccactatgtaa |
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