Homo sapiens (human): 3777
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Entry
3777 CDS
T01001
Symbol
KCNK3, K2p3.1, OAT1, PPH4, TASK, TASK-1, TASK1, TBAK1
Name
(RefSeq) potassium two pore domain channel subfamily K member 3
KO
K04914
potassium channel subfamily K member 3
Organism
hsa
Homo sapiens (human)
Pathway
hsa04925
Aldosterone synthesis and secretion
hsa04927
Cortisol synthesis and secretion
hsa04934
Cushing syndrome
Disease
H01619
Primary pulmonary hypertension
H01621
Pulmonary arterial hypertension
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09152 Endocrine system
04925 Aldosterone synthesis and secretion
3777 (KCNK3)
04927 Cortisol synthesis and secretion
3777 (KCNK3)
09160 Human Diseases
09167 Endocrine and metabolic disease
04934 Cushing syndrome
3777 (KCNK3)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
hsa04040
]
3777 (KCNK3)
Ion channels [BR:
hsa04040
]
Voltage-gated cation channels
Potassium channel, two-pore domain (K2P)
3777 (KCNK3)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ion_trans_2
Ion_trans
SelK_SelG
Motif
Other DBs
NCBI-GeneID:
3777
NCBI-ProteinID:
NP_002237
OMIM:
603220
HGNC:
6278
Ensembl:
ENSG00000171303
UniProt:
O14649
Structure
PDB
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All DBs
Position
2:26692722..26733420
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AA seq
394 aa
AA seq
DB search
MKRQNVRTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQELRARYNLSQGGYE
ELERVVLRLKPHKAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPL
TLVMFQSLGERINTLVRYLLHRAKKGLGMRRADVSMANMVLIGFFSCISTLCIGAAAFSH
YEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLN
LVVLRFMTMNAEDEKRDAEHRALLTRNGQAGGGGGGGSAHTTDTASSTAAAGGGGFRNVY
AEVLHFQSMCSCLWYKSREKLQYSIPMIIPRDLSTSDTCVEQSHSSPGGGGRYSDTPSRR
CLCSGAPRSAISSVSTGLHSLSTFRGLMKRRSSV
NT seq
1185 nt
NT seq
+upstream
nt +downstream
nt
atgaagcggcagaacgtgcgcacgctggcgctcatcgtgtgcaccttcacctacctgctg
gtgggcgccgcggtcttcgacgcgctggagtcggagcccgagctgatcgagcggcagcgg
ctggagctgcggcagcaggagctgcgggcgcgctacaacctcagccagggcggctacgag
gagctggagcgcgtcgtgctgcgcctcaagccgcacaaggccggcgtgcagtggcgcttc
gccggctccttctacttcgccatcaccgtcatcaccaccatcggctacgggcacgcggca
cccagcacggatggcggcaaggtgttctgcatgttctacgcgctgctgggcatcccgctc
acgctcgtcatgttccagagcctgggcgagcgcatcaacaccttggtgaggtacctgctg
caccgcgccaagaaggggctgggcatgcggcgcgccgacgtgtccatggccaacatggtg
ctcatcggcttcttctcgtgcatcagcacgctgtgcatcggcgccgccgccttctcccac
tacgagcactggaccttcttccaggcctactactactgcttcatcaccctcaccaccatc
ggcttcggcgactacgtggcgctgcagaaggaccaggccctgcagacgcagccgcagtac
gtggccttcagcttcgtctacatccttacgggcctcacggtcatcggcgccttcctcaac
ctcgtggtgctgcgcttcatgaccatgaacgccgaggacgagaagcgcgacgccgagcac
cgcgcgctgctcacgcgcaacgggcaggcgggcggcggcggagggggtggcagcgcgcac
actacggacaccgcctcatccacggcggcagcgggcggcggcggcttccgcaacgtctac
gcggaggtgctgcacttccagtccatgtgctcgtgcctgtggtacaagagccgcgagaag
ctgcagtactccatccccatgatcatcccgcgggacctctccacgtccgacacgtgcgtg
gagcagagccactcgtcgccgggagggggcggccgctacagcgacacgccctcgcgacgc
tgcctgtgcagcggggcgccacgctccgccatcagctcggtgtccacgggtctgcacagc
ctgtccaccttccgcggcctcatgaagcgcaggagctccgtgtga
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integrated database retrieval system
