Homo sapiens (human): 3837
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Entry
3837 CDS
T01001
Symbol
KPNB1, IMB1, IPO1, IPOB, Impnb, NTF97
Name
(RefSeq) karyopherin subunit beta 1
KO
K14293
importin subunit beta-1
Organism
hsa
Homo sapiens (human)
Pathway
hsa03013
Nucleocytoplasmic transport
hsa05207
Chemical carcinogenesis - receptor activation
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09122 Translation
03013 Nucleocytoplasmic transport
3837 (KPNB1)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
3837 (KPNB1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03009 Ribosome biogenesis [BR:
hsa03009
]
3837 (KPNB1)
03036 Chromosome and associated proteins [BR:
hsa03036
]
3837 (KPNB1)
Ribosome biogenesis [BR:
hsa03009
]
Eukaryotic type
Pre-40S particles
Export and cytoplasmic maturation factors
3837 (KPNB1)
Pre-60S particles
3837 (KPNB1)
Chromosome and associated proteins [BR:
hsa03036
]
Eukaryotic type
Centrosome formation proteins
Spindle formation proteins
3837 (KPNB1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HEAT_EZ
HEAT
IBN_N
HEAT_2
Arm
HEAT_EF3_N
Cnd1
Htt_N-HEAT_1
TPR_TNPO3_IPO13_3rd
V-ATPase_H_C
DUF6869
Motif
Other DBs
NCBI-GeneID:
3837
NCBI-ProteinID:
NP_002256
OMIM:
602738
HGNC:
6400
Ensembl:
ENSG00000108424
UniProt:
Q14974
Structure
PDB
PDBj
LinkDB
All DBs
Position
17:47649919..47685505
Genome browser
AA seq
876 aa
AA seq
DB search
MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNSQVARVAAGLQ
IKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRPSSASQCVAGIACAE
IPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQG
MRKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFIMQVVCEATQCPDTRVRVAALQN
LVKIMSLYYQYMETYMGPALFAITIEAMKSDIDEVALQGIEFWSNVCDEEMDLAIEASEA
AEQGRPPEHTSKFYAKGALQYLVPILTQTLTKQDENDDDDDWNPCKAAGVCLMLLATCCE
DDIVPHVLPFIKEHIKNPDWRYRDAAVMAFGCILEGPEPSQLKPLVIQAMPTLIELMKDP
SVVVRDTAAWTVGRICELLPEAAINDVYLAPLLQCLIEGLSAEPRVASNVCWAFSSLAEA
AYEAADVADDQEEPATYCLSSSFELIVQKLLETTDRPDGHQNNLRSSAYESLMEIVKNSA
KDCYPAVQKTTLVIMERLQQVLQMESHIQSTSDRIQFNDLQSLLCATLQNVLRKVQHQDA
LQISDVVMASLLRMFQSTAGSGGVQEDALMAVSTLVEVLGGEFLKYMEAFKPFLGIGLKN
YAEYQVCLAAVGLVGDLCRALQSNIIPFCDEVMQLLLENLGNENVHRSVKPQILSVFGDI
ALAIGGEFKKYLEVVLNTLQQASQAQVDKSDYDMVDYLNELRESCLEAYTGIVQGLKGDQ
ENVHPDVMLVQPRVEFILSFIDHIAGDEDHTDGVVACAAGLIGDLCTAFGKDVLKLVEAR
PMIHELLTEGRRSKTNKAKTLATWATKELRKLKNQA
NT seq
2631 nt
NT seq
+upstream
nt +downstream
nt
atggagctgatcaccattctcgagaagaccgtgtctcccgatcggctggagctggaagcg
gcgcagaagttcctggagcgtgcggccgtggagaacctgcccactttccttgtggaactg
tccagagtgctggcaaatccaggaaacagtcaggttgccagagttgcagctggtctacaa
atcaagaactctttgacatctaaagatccagatatcaaggcacaatatcagcagaggtgg
cttgctattgatgctaatgctcgacgagaagtcaagaactatgttttgcagacattgggt
acagaaacttaccggcctagttctgcctcacagtgtgtggctggtattgcttgtgcagag
atcccagtaaaccagtggccagaactcattcctcagctggtggccaatgtcacaaacccc
aacagcacagagcacatgaaggagtcgacattggaagccatcggttatatttgccaagat
atagacccagagcagctacaagataaatccaatgagattctgactgccataatccagggg
atgaggaaagaagagcctagtaataatgtgaagctagctgctacgaatgcactcctgaac
tcattggagttcaccaaagcaaactttgataaagagtctgaaaggcactttattatgcag
gtggtctgtgaagccacacagtgtccagatacgagggtacgagtggctgctttacagaat
ctggtgaagataatgtccttatattatcagtacatggagacatatatgggtcctgctctt
tttgcaatcacaatcgaagcaatgaaaagtgacattgatgaggtggctttacaagggata
gaattctggtccaatgtctgtgatgaggaaatggatttggccattgaagcttcagaggca
gcagaacaaggacggccccctgagcacaccagcaagttttatgcgaagggagcactacag
tatctggttccaatcctcacacagacactaactaaacaggacgaaaatgatgatgacgat
gactggaacccctgcaaagcagcaggggtgtgcctcatgcttctggccacctgctgtgaa
gatgacattgtcccacatgtcctccccttcattaaagaacacatcaagaacccagattgg
cggtaccgggatgcagcagtgatggcttttggttgtatcttggaaggaccagagcccagt
cagctcaaaccactagttatacaggctatgcccaccctaatagaattaatgaaagacccc
agtgtagttgttcgagatacagctgcatggactgtaggcagaatttgtgagctgcttcct
gaagctgccatcaatgatgtctacttggctcccctgctacagtgtctgattgagggtctc
agtgctgaacccagagtggcttcaaatgtgtgctgggctttctccagtctggctgaagct
gcttatgaagctgcagacgttgctgatgatcaggaagaaccagctacttactgcttatct
tcttcatttgaactcatagttcagaagctcctagagactacagacagacctgatggacac
cagaacaacctgaggagttctgcatatgaatctctgatggaaattgtgaaaaacagtgcc
aaggattgttatcctgctgtccagaaaacgactttggtcatcatggaacgactgcaacag
gttcttcagatggagtcacatatccagagcacatccgatagaatccagttcaatgacctt
cagtctttactctgtgcaactcttcagaatgttcttcggaaagtgcaacatcaagatgct
ttgcagatctctgatgtggttatggcctccctgttaaggatgttccaaagcacagctggg
tctgggggagtacaagaggatgccctgatggcagttagcacactggtggaagtgttgggt
ggtgaattcctcaagtacatggaggcctttaaacccttcctgggcattggattaaaaaat
tatgctgaataccaggtttgtttggcagctgtgggcttagtgggagacttgtgccgtgcc
ctgcaatccaacatcatacctttctgtgacgaggtgatgcagctgcttctggaaaatttg
gggaatgagaacgtccacaggtctgtgaagccgcagattctgtcagtgtttggtgatatt
gcccttgctattggaggagagtttaaaaaatacttagaggttgtattgaatactcttcag
caggcctcccaagcccaggtggacaagtcagactatgacatggtggattatctgaatgag
ctaagggaaagctgcttggaagcctatactggaatcgtccagggattaaagggggatcag
gagaacgtacacccggatgtgatgctggtacaacccagagtagaatttattctgtctttc
attgaccacattgctggagatgaggatcacacagatggagtagtagcttgtgctgctgga
ctaataggggacttatgtacagcatttgggaaggatgtactgaaattagtagaagctagg
ccaatgatccatgaattgttaactgaagggcggagatcgaagactaacaaagcaaaaacc
cttgctacatgggcaacaaaagaactgaggaaactgaagaaccaagcttga
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