Homo sapiens (human): 3854
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Entry
3854 CDS
T01001
Symbol
KRT6B, CK-6B, CK6B, K6B, KRTL1, PC2, PC4
Name
(RefSeq) keratin, type II cytoskeletal 6B
KO
K07605
type II keratin, basic
Organism
hsa
Homo sapiens (human)
Pathway
hsa04382
Cornified envelope formation
hsa04519
Cadherin signaling
Disease
H00684
Pachyonychia congenita
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04519 Cadherin signaling
3854 (KRT6B)
09150 Organismal Systems
09158 Development and regeneration
04382 Cornified envelope formation
3854 (KRT6B)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
hsa04812
]
3854 (KRT6B)
04147 Exosome [BR:
hsa04147
]
3854 (KRT6B)
Cytoskeleton proteins [BR:
hsa04812
]
Eukaryotic cytoskeleton proteins
Intermediate filaments
Intermediate filaments
Types I and II: Acidic and basic keratins
3854 (KRT6B)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of epithelial cells
3854 (KRT6B)
Exosomal proteins of other body fluids (saliva and urine)
3854 (KRT6B)
Exosomal proteins of colorectal cancer cells
3854 (KRT6B)
Exosomal proteins of bladder cancer cells
3854 (KRT6B)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Filament
Keratin_2_head
TPR_MLP1_2
CENP-F_leu_zip
CCDC39
FKBP15
DUF8776
COG6_N
ATG16
Plectin_PPL
KIF21A_4th
CEP135_TSGA10_CC
DUF745
CCDC89
Alanine_zipper
ODF2_C
Sec10_N
CLIP1
NNF2_middle
DUF7217
ATG17_like
RNase_PH
Baculo_PEP_C
FapA
DUF948
DUF2740
CCDC170_1st
UPF0184
WIT1_2_N
BNI5_helical
Glutaredoxin2_C
PUMA_CC
V_ATPase_I
Ninein_long_CC
ANC1_spectrin
SPC25_N
Motif
Other DBs
NCBI-GeneID:
3854
NCBI-ProteinID:
NP_005546
OMIM:
148042
HGNC:
6444
Ensembl:
ENSP00000252252.3
UniProt:
P04259
LinkDB
All DBs
Position
12:complement(52446651..52452146)
Genome browser
AA seq
564 aa
AA seq
DB search
MASTSTTIRSHSSSRRGFSANSARLPGVSRSGFSSISVSRSRGSGGLGGACGGAGFGSRS
LYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAG
GFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFASFIDK
VRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDNIVGERGRLDSELR
NMQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRA
LYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKY
EELQITAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMAL
KDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEG
VGQVNISVVQSTVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRATGGGLS
SVGGGSSTIKYTTTSSSSRKSYKH
NT seq
1695 nt
NT seq
+upstream
nt +downstream
nt
atggccagcacatccaccaccatcaggagccacagcagcagccgccggggtttcagtgcc
aactcagccaggctccctggggtcagccgctctggcttcagcagcatctccgtgtcccgc
tccaggggcagtggtggcctgggtggcgcatgtggaggagctggctttggcagccgcagt
ctgtatggcctggggggctccaagaggatctccattggagggggcagctgtgccatcagt
ggcggctatggcagcagagccggaggcagctatggctttggtggcgccgggagtggattt
ggtttcggtggtggagccggcattggctttggtctgggtggtggagccggccttgctggt
ggctttgggggccctggcttccctgtgtgcccccctggaggcatccaagaggtcactgtc
aaccagagtctcctgactcccctcaacctgcaaattgaccccgccatccagcgggtgcgg
gccgaggagcgtgagcagatcaagaccctcaacaacaagtttgcctccttcatcgacaag
gtgcggttcctagagcagcagaacaaggttctggacaccaagtggaccctgctgcaggag
cagggcaccaagactgtgaggcagaacctggagccgttgttcgagcagtacatcaacaac
ctcaggaggcagctggacaacatcgtgggggaacggggtcgtctggactcggagctgaga
aacatgcaggacctggtggaggacctcaagaacaaatatgaggatgaaatcaacaagcgc
acagcagcagagaatgaatttgtgactctgaagaaggatgtggatgctgcctacatgaac
aaggttgaactgcaagccaaggcagacactcttacagatgagatcaacttcctgagagcc
ttgtatgatgcagagctgtcccagatgcagacccacatctcagacacatccgtggtgcta
tccatggacaacaaccgcaacctggacctggacagcatcatcgctgaggtcaaggcccaa
tatgaggagattgctcagaggagcagggctgaggctgagtcctggtaccagacaaagtac
gaggagctgcagatcacagcaggcagacatggggacgacctgcgcaacaccaagcaggag
attgctgagatcaaccgcatgatccagaggctgagatctgagatcgaccacgtcaagaag
cagtgtgccaacctacaggccgccattgctgatgctgagcagcgtggggagatggccctc
aaggatgctaagaacaagctggaagggctggaggatgccctgcagaaggccaagcaggac
ctggcccggctgctgaaggagtaccaggagctgatgaacgtcaagctggccctggatgtg
gagatcgccacctaccgcaagctgctggagggcgaggagtgcaggctgaatggcgaaggc
gttggacaagtcaacatctctgtagtgcagtccaccgtctccagtggctatggcggtgcc
agcggtgtcggcagtggcttaggcctgggtggaggaagcagctactcctatggcagtggt
cttggcgttggaggcggctttagttccagcagcggcagagccactgggggtggcctcagc
tctgttggaggcggcagttccaccatcaagtacaccaccacctcctcctccagcaggaag
agctacaagcactga
DBGET
integrated database retrieval system
