KEGG   Homo sapiens (human): 3859
Entry
3859              CDS       T01001                                 
Symbol
KRT12, K12, MECD1
Name
(RefSeq) keratin 12
  KO
K07604  type I keratin, acidic
Organism
hsa  Homo sapiens (human)
Pathway
hsa04382  Cornified envelope formation
hsa04915  Estrogen signaling pathway
hsa05150  Staphylococcus aureus infection
Disease
H00726  Meesmann corneal dystrophy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04915 Estrogen signaling pathway
    3859 (KRT12)
  09158 Development and regeneration
   04382 Cornified envelope formation
    3859 (KRT12)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05150 Staphylococcus aureus infection
    3859 (KRT12)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    3859 (KRT12)
   04147 Exosome [BR:hsa04147]
    3859 (KRT12)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Intermediate filaments
   Intermediate filaments
    Types I and II: Acidic and basic keratins
     3859 (KRT12)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of epithelial cells
   3859 (KRT12)
  Exosomal proteins of other body fluids (saliva and urine)
   3859 (KRT12)
  Exosomal proteins of colorectal cancer cells
   3859 (KRT12)
  Exosomal proteins of melanoma cells
   3859 (KRT12)
SSDB
Motif
Pfam: Filament TPR_MLP1_2 Myosin_tail_1 AIF-1 UPF0242
Other DBs
NCBI-GeneID: 3859
NCBI-ProteinID: NP_000214
OMIM: 601687
HGNC: 6414
Ensembl: ENSG00000187242
UniProt: Q99456
LinkDB
Position
17:complement(40861303..40867223)
AA seq 494 aa
MDLSNNTMSLSVRTPGLSRRLSSQSVIGRPRGMSASSVGSGYGGSAFGFGASCGGGFSAA
SMFGSSSGFGGGSGSSMAGGLGAGYGRALGGGSFGGLGMGFGGSPGGGSLGILSGNDGGL
LSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRGTGTADASQSDYSKYY
PLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELALRQGVEADINGLRRVLD
ELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVGGPGEVSVEMDAAPGVDLTRLLND
MRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTDLRRAFQNLEIELQ
SQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAERQNVDHQRLLNVKA
RLELEIETYRRLLDGEAQGDGLEESLFVTDSKSQAQSTDSSKDPTKTRKIKTVVQEMVNG
EVVSSQVQEIEELM
NT seq 1485 nt   +upstreamnt  +downstreamnt
atggatctctccaacaacaccatgtcactctcagtgcgcacccccggactgtcccggcgg
ctctcctcgcagagtgtgataggcagacccaggggcatgtctgcttccagtgttggaagt
ggttatgggggaagtgcctttggctttggagccagctgtgggggaggcttttctgctgct
tccatgtttggttctagttccggctttgggggtggctccggaagttccatggcaggagga
ctgggtgctggttatgggagagccctgggtggaggtagctttggagggctggggatggga
tttgggggcagcccaggaggtggctctctaggtattctctcgggcaatgatggaggcctt
ctttctggatcagaaaaagaaactatgcaaaatcttaatgatagattagcttcctacctg
gataaggtgcgagctctagaagaggctaatactgagctagaaaataaaattcgagaatgg
tatgaaacacgaggaactgggactgcagatgcttcacagagcgattacagcaaatattat
ccactgattgaagacctcaggaataagatcatttcagccagcattggaaatgcccagctc
ctcttgcagattgacaatgcgagactagctgctgaggacttcaggatgaagtatgagaat
gaactggccctgcgccagggcgtagaggccgacatcaatggcctgcgccgggtgctggac
gagctgaccctgaccaggaccgacctggagatgcagatcgagagcctgaacgaggagctg
gcctacatgaagaagaaccacgaggatgagctccaaagcttccgggtgggcggcccaggc
gaggtcagcgtagaaatggacgctgcccccggagtggacctcaccaggctcctcaatgat
atgcgggcgcagtatgaaaccatcgctgagcagaatcggaaggacgctgaagcctggttc
attgaaaagagcggggagctccgtaaggagattagcaccaacaccgagcagcttcagtcc
agcaagagcgaggtcaccgacctgcgtcgcgcctttcagaacctggagatcgagctacag
tcccagctcgccatgaagaaatccctggaggactccttggccgaagccgagggcgattac
tgcgcgcagctgtcccaggtgcagcagctcatcagcaacctggaggcacagctgctccag
gtgcgcgcggacgcagagcgccagaacgtggaccaccagcggctgctgaatgtcaaggcc
cgcctggagctggagattgagacctaccgccgcctgctggacggggaggcccaaggtgat
ggtttggaggaaagtttatttgtgacagactccaaatcacaagcacagtcaactgattcc
tctaaagacccaaccaaaacccgaaaaatcaagacagttgtgcaggagatggtgaatggt
gaggtggtctcatctcaagttcaggaaattgaagaactaatgtaa

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