Homo sapiens (human): 3902
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Entry
3902 CDS
T01001
Symbol
LAG3, CD223
Name
(RefSeq) lymphocyte activating 3
KO
K06565
lymphocyte-activation gene 3 protein
Organism
hsa
Homo sapiens (human)
Drug target
Bavunalimab:
D12317
Favezelimab:
D12469
Ieramilimab:
D12156
Relatlimab:
D11350
Tobemstomig:
D12961
Tuparstobart:
D12480
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
hsa04090
]
3902 (LAG3)
CD molecules [BR:
hsa04090
]
Proteins
3902 (LAG3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ig_3
ig
V-set
Ig_2
I-set
Ig_6
Trypan_PARP
stn_TNFRSF12A
TarH
Motif
Other DBs
NCBI-GeneID:
3902
NCBI-ProteinID:
NP_002277
OMIM:
153337
HGNC:
6476
Ensembl:
ENSG00000089692
UniProt:
P18627
Structure
PDB
PDBj
LinkDB
All DBs
Position
12:6772520..6778455
Genome browser
AA seq
525 aa
AA seq
DB search
MWEAQFLGLLFLQPLWVAPVKPLQPGAEVPVVWAQEGAPAQLPCSPTIPLQDLSLLRRAG
VTWQHQPDSGPPAAAPGHPLAPGPHPAAPSSWGPRPRRYTVLSVGPGGLRSGRLPLQPRV
QLDERGRQRGDFSLWLRPARRADAGEYRAAVHLRDRALSCRLRLRLGQASMTASPPGSLR
ASDWVILNCSFSRPDRPASVHWFRNRGQGRVPVRESPHHHLAESFLFLPQVSPMDSGPWG
CILTYRDGFNVSIMYNLTVLGLEPPTPLTVYAGAGSRVGLPCRLPAGVGTRSFLTAKWTP
PGGGPDLLVTGDNGDFTLRLEDVSQAQAGTYTCHIHLQEQQLNATVTLAIITVTPKSFGS
PGSLGKLLCEVTPVSGQERFVWSSLDTPSQRSFSGPWLEAQEAQLLSQPWQCQLYQGERL
LGAAVYFTELSSPGAQRSGRAPGALPAGHLLLFLILGVLSLLLLVTGAFGFHLWRRQWRP
RRFSALEQGIHPPQAQSKIEELEQEPEPEPEPEPEPEPEPEPEQL
NT seq
1578 nt
NT seq
+upstream
nt +downstream
nt
atgtgggaggctcagttcctgggcttgctgtttctgcagccgctttgggtggctccagtg
aagcctctccagccaggggctgaggtcccggtggtgtgggcccaggagggggctcctgcc
cagctcccctgcagccccacaatccccctccaggatctcagccttctgcgaagagcaggg
gtcacttggcagcatcagccagacagtggcccgcccgctgccgcccccggccatcccctg
gcccccggccctcacccggcggcgccctcctcctgggggcccaggccccgccgctacacg
gtgctgagcgtgggtcccggaggcctgcgcagcgggaggctgcccctgcagccccgcgtc
cagctggatgagcgcggccggcagcgcggggacttctcgctatggctgcgcccagcccgg
cgcgcggacgccggcgagtaccgcgccgcggtgcacctcagggaccgcgccctctcctgc
cgcctccgtctgcgcctgggccaggcctcgatgactgccagccccccaggatctctcaga
gcctccgactgggtcattttgaactgctccttcagccgccctgaccgcccagcctctgtg
cattggttccggaaccggggccagggccgagtccctgtccgggagtccccccatcaccac
ttagcggaaagcttcctcttcctgccccaagtcagccccatggactctgggccctggggc
tgcatcctcacctacagagatggcttcaacgtctccatcatgtataacctcactgttctg
ggtctggagcccccaactcccttgacagtgtacgctggagcaggttccagggtggggctg
ccctgccgcctgcctgctggtgtggggacccggtctttcctcactgccaagtggactcct
cctgggggaggccctgacctcctggtgactggagacaatggcgactttacccttcgacta
gaggatgtgagccaggcccaggctgggacctacacctgccatatccatctgcaggaacag
cagctcaatgccactgtcacattggcaatcatcacagtgactcccaaatcctttgggtca
cctggatccctggggaagctgctttgtgaggtgactccagtatctggacaagaacgcttt
gtgtggagctctctggacaccccatcccagaggagtttctcaggaccttggctggaggca
caggaggcccagctcctttcccagccttggcaatgccagctgtaccagggggagaggctt
cttggagcagcagtgtacttcacagagctgtctagcccaggtgcccaacgctctgggaga
gccccaggtgccctcccagcaggccacctcctgctgtttctcatccttggtgtcctttct
ctgctccttttggtgactggagcctttggctttcacctttggagaagacagtggcgacca
agacgattttctgccttagagcaagggattcaccctccgcaggctcagagcaagatagag
gagctggagcaagaaccggagccggagccggagccggaaccggagcccgagcccgagccc
gagccggagcagctctga
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