Homo sapiens (human): 3985
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Entry
3985 CDS
T01001
Symbol
LIMK2
Name
(RefSeq) LIM domain kinase 2
KO
K05744
LIM domain kinase 2 [EC:
2.7.11.1
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04360
Axon guidance
hsa04666
Fc gamma R-mediated phagocytosis
hsa04810
Regulation of actin cytoskeleton
hsa05170
Human immunodeficiency virus 1 infection
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
3985 (LIMK2)
09150 Organismal Systems
09151 Immune system
04666 Fc gamma R-mediated phagocytosis
3985 (LIMK2)
09158 Development and regeneration
04360 Axon guidance
3985 (LIMK2)
09160 Human Diseases
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
3985 (LIMK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
3985 (LIMK2)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
3985 (LIMK2)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: TKL group
LISK family [OT]
3985 (LIMK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
LIM
PDZ
Kdo
PDZ_6
PDZ_2
ABC1
APH
Motif
Other DBs
NCBI-GeneID:
3985
NCBI-ProteinID:
NP_005560
OMIM:
601988
HGNC:
6614
Ensembl:
ENSG00000182541
UniProt:
P53671
Structure
PDB
PDBj
LinkDB
All DBs
Position
22:31212298..31280080
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AA seq
638 aa
AA seq
DB search
MSALAGEDVWRCPGCGDHIAPSQIWYRTVNETWHGSCFRCSECQDSLTNWYYEKDGKLYC
PKDYWGKFGEFCHGCSLLMTGPFMVAGEFKYHPECFACMSCKVIIEDGDAYALVQHATLY
CGKCHNEVVLAPMFERLSTESVQEQLPYSVTLISMPATTEGRRGFSVSVESACSNYATTV
QVKEVNRMHISPNNRNAIHPGDRILEINGTPVRTLRVEEVEDAISQTSQTLQLLIEHDPV
SQRLDQLRLEARLAPHMQNAGHPHALSTLDTKENLEGTLRRRSLRRSNSISKSPGPSSPK
EPLLFSRDISRSESLRCSSSYSQQIFRPCDLIHGEVLGKGFFGQAIKVTHKATGKVMVMK
ELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRSM
DPFPWQQKVRFAKGIASGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIVEER
KRAPMEKATTKKRTLRKNDRKKRYTVVGNPYWMAPEMLNGKSYDETVDIFSFGIVLCEII
GQVYADPDCLPRTLDFGLNVKLFWEKFVPTDCPPAFFPLAAICCRLEPESRPAFSKLEDS
FEALSLYLGELGIPLPAELEELDHTVSMQYGLTRDSPP
NT seq
1917 nt
NT seq
+upstream
nt +downstream
nt
atgtccgcgctggcgggtgaagatgtctggaggtgtccaggctgtggggaccacattgct
ccaagccagatatggtacaggactgtcaacgaaacctggcacggctcttgcttccggtgt
tcagaatgccaggattccctcaccaactggtactatgagaaggatgggaagctctactgc
cccaaggactactgggggaagtttggggagttctgtcatgggtgctccctgctgatgaca
gggccttttatggtggctggggagttcaagtaccacccagagtgctttgcctgtatgagc
tgcaaggtgatcattgaggatggggatgcatatgcactggtgcagcatgccaccctctac
tgtgggaagtgccacaatgaggtggtgctggcacccatgtttgagagactctccacagag
tctgttcaggagcagctgccctactctgtcacgctcatctccatgccggccaccactgaa
ggcaggcggggcttctccgtgtccgtggagagtgcctgctccaactacgccaccactgtg
caagtgaaagaggtcaaccggatgcacatcagtcccaacaatcgaaacgccatccaccct
ggggaccgcatcctggagatcaatgggacccccgtccgcacacttcgagtggaggaggtg
gaggatgcaattagccagacgagccagacacttcagctgttgattgaacatgaccccgtc
tcccaacgcctggaccagctgcggctggaggcccggctcgctcctcacatgcagaatgcc
ggacacccccacgccctcagcaccctggacaccaaggagaatctggaggggacactgagg
agacgttccctaaggcgcagtaacagtatctccaagtcccctggccccagctccccaaag
gagcccctgctgttcagccgtgacatcagccgctcagaatcccttcgttgttccagcagc
tattcacagcagatcttccggccctgtgacctaatccatggggaggtcctggggaagggc
ttctttgggcaggctatcaaggtgacacacaaagccacgggcaaagtgatggtcatgaaa
gagttaattcgatgtgatgaggagacccagaaaacttttctgactgaggtgaaagtgatg
cgcagcctggaccaccccaatgtgctcaagttcattggtgtgctgtacaaggataagaag
ctgaacctcctgacagagtacattgaggggggcacactgaaggactttctgcgcagtatg
gatccgttcccctggcagcagaaggtcaggtttgccaaaggaatcgcctccggaatggcc
tatttgcactctatgtgcatcatccaccgggatctgaactcgcacaactgcctcatcaag
ttggacaagactgtggtggtggcagactttgggctgtcacggctcatagtggaagagagg
aaaagggcccccatggagaaggccaccaccaagaaacgcaccttgcgcaagaacgaccgc
aagaagcgctacacggtggtgggaaacccctactggatggcccctgagatgctgaacgga
aagagctatgatgagacggtggatatcttctcctttgggatcgttctctgtgagatcatt
gggcaggtgtatgcagatcctgactgccttccccgaacactggactttggcctcaacgtg
aagcttttctgggagaagtttgttcccacagattgtcccccggccttcttcccgctggcc
gccatctgctgcagactggagcctgagagcagaccagcattctcgaaattggaggactcc
tttgaggccctctccctgtacctgggggagctgggcatcccgctgcctgcagagctggag
gagttggaccacactgtgagcatgcagtacggcctgacccgggactcacctccctag
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