Homo sapiens (human): 3996
Help
Entry
3996 CDS
T01001
Symbol
LLGL1, DLG4, HUGL, HUGL-1, HUGL1, LLGL, Lgl1, Mgl1
Name
(RefSeq) lethal(2) giant larvae protein homolog 1
KO
K06094
lethal(2) giant larvae protein
Organism
hsa
Homo sapiens (human)
Pathway
hsa04390
Hippo signaling pathway
hsa04530
Tight junction
hsa05165
Human papillomavirus infection
Network
nt06166
Human papillomavirus (HPV)
Element
N00340
The Scribble/Dlg/Lgl polarity module
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04390 Hippo signaling pathway
3996 (LLGL1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04530 Tight junction
3996 (LLGL1)
09160 Human Diseases
09172 Infectious disease: viral
05165 Human papillomavirus infection
3996 (LLGL1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
3996 (LLGL1)
Membrane trafficking [BR:
hsa04131
]
Exocytosis
Small GTPases and associated proteins
Rab associated proteins
3996 (LLGL1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
LLGL
Beta-prop_IFT122_1st
Beta-prop_WDR3_1st
Beta-prop_THOC3
Beta-prop_EML_2
WD40
Beta-prop_WDR5
Beta-prop_IFT140_1st
Beta-prop_WDR36-Utp21_1st
Lgl_C
Beta-prop_VPS8
Beta-prop_WDR90_POC16_2nd
Motif
Other DBs
NCBI-GeneID:
3996
NCBI-ProteinID:
NP_004131
OMIM:
600966
HGNC:
6628
Ensembl:
ENSP00000321537.4
UniProt:
Q15334
Structure
PDB
PDBj
LinkDB
All DBs
Position
17:18225635..18244875
Genome browser
AA seq
1064 aa
AA seq
DB search
MMKFRFRRQGADPQREKLKQELFAFNKTVEHGFPNQPSALAFDPELRIMAIGTRSGAVKI
YGAPGVEFTGLHRDAATVTQMHFLTGQGRLLSLLDDSSLHLWEIVHHNGCAHLEEALSFQ
LPSRPGFDGASAPLSLTRVTVVLLVAASDIAALGTEGSSVFFLDVTTLTLLEGQTLAPGE
VLRSVPDDYRCGKALGPVESLQGHLRDPTKILIGYSRGLLVIWNQASQCVDHIFLGNQQL
ESLCWGRDSSTVVSSHSDGSYAVWSVDAGSFPTLQPTVATTPYGPFPCKAINKILWRNCE
SGGHFIIFSGGMPRASYGDRHCVSVLRAETLVTLDFTSRIIDFFTVHSTRPEDEFDDPQA
LAVLLEEELVVLDLQTPGWPAVPAPYLAPLHSSAITCSAHVASVPAKLWARIVSAGEQQS
PQPVSSALSWPITGGRNLAQEPSQRGLLLTGHEDGTVRFWDASGVALRPLYKLSTAGLFQ
TDCEHADSLAQAAEDDWPPFRKVGCFDPYSDDPRLGVQKVALCKYTAQMVVAGTAGQVLV
LELSDVPVEQAVSVAIIDLLQDREGFTWKGHERLSPRTGPLPWPAGFQPRVLVQCLPPAA
VTAVTLHTEWSLVAFGTSHGFGLFDYQRKSPVLARCTLHPNDSLAMEGPLSRVKSLKKSL
RQSFRRIRKSRVSGKKRAANASSKLQEANAQLAEQACPHDVEMTPVQRRIEPRSADDSLS
GVVRCLYFADTFLRDGAHHGPTMWAGTNSGSVFAYALEVPAAAVGGEKRPEQAVEAVLGK
EVQLMHRAPVVAIAVLDGRGRPLPEPYEASRDLAQAPDMQGGHAVLIASEEQFKVFTLPK
VSAKTKFKLTAHEGCRVRKVALATFASVACEDYAETCLACLTNLGDVHVFSVPGLRPQVH
YSCIRKEDISGIASCVFTRHGQGFYLISPSEFERFSLSARNITEPLCSLDINWPRDATQA
SYRIRESPKLSQANGTPSILLAPQSLDGSPDPAHSMGPDTPEPPEAALSPMSIDSATSAD
TTLDTTGDVTVEDVKDFLGSSEESEKNLRNLAEDEAHACAILIK
NT seq
3195 nt
NT seq
+upstream
nt +downstream
nt
atgatgaagtttcggttccggcggcagggcgccgacccgcagcgcgagaagctcaagcag
gagcttttcgccttcaacaagactgtggagcatggcttccccaatcagcccagcgccctg
gccttcgacccggaacttcgcatcatggccatcggcaccaggtctggggctgtcaagatc
tatggtgcacctggcgtggagttcacaggcctgcaccgggatgcagccactgtcacacag
atgcacttcttgaccggccagggccgcctcctgtccctgcttgatgacagcagtctgcat
ctctgggagattgtccaccataatggctgtgcccacctggaagaagcactcagtttccag
ctgcccagccggcccggctttgatggtgccagtgctccgctcagccttacccgagtcaca
gtggtcctgctggtggctgccagcgacatagcagccctgggcactgagggcagcagtgtc
ttcttcctggatgttaccaccctgaccctgctcgaggggcagacgcttgccccaggcgag
gttctgcgcagcgtgccagacgactaccgctgtgggaaggcactgggccccgtggagtca
ctccagggacacctgcgggaccccacaaagattctcattggctacagccggggcctgctg
gtcatctggaaccaggcctcgcagtgtgtggaccacatcttcctggggaaccagcagctg
gagagcctatgctgggggcgtgatagcagcactgtggtcagctcacacagcgatggcagc
tatgctgtctggtctgtggatgccggcagcttcccaacgctgcagcccacggtagccacc
acaccttacggcccctttccctgcaaggccattaacaagattctgtggcggaactgtgaa
tctgggggccactttatcatcttcagcggtggcatgccccgtgccagctatggtgaccgc
cactgtgtaagtgtgcttcgagccgagacattggtgacgctggacttcacttcccgcatc
atcgacttcttcacagtgcacagcacacggcccgaggatgaatttgatgacccccaggcc
ctggctgtgctgctggaagaggagctggtggtgctggacctgcagactcctggctggcca
gctgtgcctgccccatacctggccccgctgcactcctctgcaatcacttgctcggcccac
gtggccagtgtccccgccaagctgtgggcccgcattgtgagcgctggcgagcagcagagc
ccccagcctgtctccagtgccttgagctggcccatcactgggggccgaaacctggcccag
gagccgtcacagcgagggctgctgctgacgggccatgaggacggcaccgtgaggttctgg
gatgcctcgggtgtggcgctgcggccgctctataagctgagcacagctggcctcttccag
acagactgtgagcacgctgacagcctggcccaggctgccgaggacgactggccacccttc
cgcaaggtgggctgcttcgatccctacagtgacgatccccggcttggcgtgcagaaggtt
gctctctgcaagtatacagcccagatggtggtggctggcactgcaggccaggtgctggta
ctggagcttagtgatgtgccggtggagcaggcggtcagcgtggccatcatagacctcctc
caggaccgcgagggcttcacatggaagggccacgagcggctgagcccacgcacggggccg
ctgccctggcctgctggcttccagccccgtgtcctggtgcagtgcctgccgccagctgct
gtaaccgctgtcacactccacaccgagtggagcctcgtggcttttggcaccagtcatggc
tttggcctcttcgactaccagcgcaagagccctgtgctggccaggtgcactcttcacccc
aatgactccctggccatggagggtccgctctcccgggtgaagtctctcaagaagtcactg
cgccagtctttccggcgcattcgcaagagtcgtgtctctggcaagaagcgggctgctaat
gccagcagcaagttgcaggaagccaatgcacagctggctgagcaggcctgcccccacgac
gtggagatgacgcccgtgcagcgccgcattgagccccgctctgccgatgactccttgtcg
ggtgtcgtgcgttgcctatactttgccgacacattccttcgagatggggcccaccacggg
cccaccatgtgggctggcaccaactcaggctctgtgttcgcctatgcactggaggtgccg
gcagcagcagtgggtggtgagaagcggcctgagcaagcggtggaggccgtgctgggcaag
gaggtgcagctgatgcaccgggcgcctgtggtggccattgccgtgttggacgggcgtggc
cgcccactgcccgagccctacgaggcctcacgggacctggcgcaggcacctgacatgcag
ggtggtcacgctgtgctcatcgcatctgaggagcagttcaaggtgttcacactgcccaag
gtgagcgcgaagaccaagttcaagctgacggcccatgagggctgtcgtgtgcgcaaggtg
gcactggccacgtttgccagtgtggcctgcgaggactatgctgagacctgcctggcctgc
ctcaccaacctgggtgacgtccacgtcttctcggtgcctggcctgcggccccaggtgcac
tattcctgcatccggaaggaggacatcagcggcatcgcttcgtgcgtctttacgcgccat
ggccagggcttttacctgatatccccatcagaatttgaacgcttctccctaagtgcccgg
aacatcacagagccgctctgctctctggacattaactggccccgcgatgccacccaggcc
agttacaggatccgagagtcacccaagctgagccaggctaacgggaccccaagcatcctg
ctggccccacagagccttgatggaagccctgatccagcccacagcatgggacctgacacc
ccggagccacccgaggctgcactctcacccatgtccatcgactcagccaccagtgctgac
accacgctggacacgacaggggacgtcacagtggaagatgtgaaggatttcctgggctcc
tctgaggagtcagagaagaacctgaggaacctggcagaagacgaggcccacgcctgtgcc
atcctgatcaaatga
Homo sapiens (human): 3993
Help
Entry
3993 CDS
T01001
Symbol
LLGL2, HGL, Hugl-2, LGL2
Name
(RefSeq) LLGL scribble cell polarity complex component 2 isoform c
KO
K06094
lethal(2) giant larvae protein
Organism
hsa
Homo sapiens (human)
Pathway
hsa04390
Hippo signaling pathway
hsa04530
Tight junction
hsa05165
Human papillomavirus infection
Network
nt06166
Human papillomavirus (HPV)
Element
N00340
The Scribble/Dlg/Lgl polarity module
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04390 Hippo signaling pathway
3993 (LLGL2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04530 Tight junction
3993 (LLGL2)
09160 Human Diseases
09172 Infectious disease: viral
05165 Human papillomavirus infection
3993 (LLGL2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
3993 (LLGL2)
Membrane trafficking [BR:
hsa04131
]
Exocytosis
Small GTPases and associated proteins
Rab associated proteins
3993 (LLGL2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
LLGL
Beta-prop_WDR3_1st
Beta-prop_IFT122_1st
Beta-prop_THOC3
Beta-prop_WDR36-Utp21_1st
WD40
Beta-prop_EML_2
Beta-prop_WDR5
WD40_CDC20-Fz
Beta-prop_WDR35_TULP_N
Beta-prop_VPS8
Beta-prop_WDR90_POC16_2nd
Beta-prop_WDR3_2nd
Beta-prop_IFT140_1st
Lgl_C
PEP5_VPS11_N
SHKBP1_KCTD3_C
Motif
Other DBs
NCBI-GeneID:
3993
NCBI-ProteinID:
NP_001026973
OMIM:
618483
HGNC:
6629
Ensembl:
ENSP00000376333.4
UniProt:
Q6P1M3
A0PJJ0
Structure
PDB
PDBj
LinkDB
All DBs
Position
17:75525002..75575209
Genome browser
AA seq
1020 aa
AA seq
DB search
MRRFLRPGHDPVRERLKRDLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYG
APGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESFTLR
GPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPE
EARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQR
DGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWLTTRQGLPFTIF
QGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEE
LVVIDLQTAGWPPVQLPYLASLHCSAITCSHHVSNIPLKLWERIIAAGSRQNAHFSTMEW
PIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVFLTDTDPNENFS
AQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQ
AVEQVEADLLQDQEGYRWKGHERLAARSGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEW
RLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKSLRQSFRRMRRS
RVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFAD
TYLKDSSRHCPSLWAGTNGGTIYAFSLRVPPAERRMDEPVRAEQAKEIQLMHRAPVVGIL
VLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSAKLKLKLTALEG
SRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIAS
CVFTKYGQGFYLISPSEFERFSLSTKWLVEPRCLVDSAETKNHRPGNGAGPKKAPSRARN
SGTQSDGEEKQPGLVMERALLSDERVLKEIQSTLEGDRGSGNWRSHRAAVGCSLSNGGAE
NT seq
3063 nt
NT seq
+upstream
nt +downstream
nt
atgaggcggttcctgaggccagggcatgaccctgtgcgggagaggctcaagcgggacctg
ttccagtttaacaagacggtggagcatggcttcccgcaccagcccagcgccctcggctac
agcccgtccctgcgcatcctggccatcggcacccgttctggagccatcaagctctacgga
gccccaggcgtggagttcatggggctgcaccaggagaacaacgctgtgacgcagatccac
ctcctgcccggccagtgccagctggtcaccctgctggatgacaacagcctgcacctttgg
agcctgaaggtcaagggcggggcatcggagctgcaggaggatgagagcttcacactgcgt
ggacccccaggggctgcccccagtgccacacagatcaccgtggtcctgccacattcctcc
tgcgagctgctctacctgggcaccgagagtggcaacgtgtttgtggtgcagctgccagct
tttcgtgcgctggaggaccggaccatcagctcggacgcggtgctgcagcggttgccagag
gaggcccgccaccggcgtgtgttcgagatggtggaggcactgcaggagcaccctcgagac
cccaaccagatcctgatcggctacagccgaggcctcgttgtcatctgggacctacagggc
agccgcgtgctctaccacttcctcagcagccagcaactggagaacatctggtggcagcgg
gacggccgcctgctcgtcagctgtcactctgacggcagctactgccagtggcccgtgtcc
agcgaagcccagcaaccagagcccctccgcagcctcgtgccttacggtccctttccttgc
aaagcgattaccagaatcctctggctgaccactaggcaggggttgcccttcaccatcttc
cagggtggcatgccacgggccagctacggggaccgccactgcatctcagtgatccacgat
ggccagcagacggccttcgacttcacctcccgtgtcatcggcttcactgtcctcacagag
gcagaccctgcagccacctttgacgacccctatgccctggtggtgctggctgaggaggag
ctggtggtgattgacctgcagacagcaggctggccaccggtccagctgccctacctggct
tctctgcactgttccgccatcacctgctctcaccacgtctccaacatcccgctgaagctg
tgggagcggatcattgccgccggcagccggcagaacgcacacttctccaccatggagtgg
ccaattgatggtggcaccagcctgaccccagccccaccccagagggacctgctgctcaca
gggcacgaggacggcacggtgcggttctgggatgcctcgggtgtctgcctgcggctgctc
tacaaactcagcactgtgcgcgtgttcctcaccgacacggaccccaacgagaacttcagt
gcccagggcgaggacgagtggcccccactccgcaaggtgggctcctttgacccctacagt
gatgacccccggctgggcatccagaagatcttcctctgcaagtacagcggctacctggct
gtggcaggcacggcagggcaggtgctggtactggaactgaatgacgaggcagcggagcag
gctgtggagcaggtggaggccgacctgctgcaggaccaagagggctaccgctggaagggg
cacgagcgcctggcagcccgctcagggcccgtgcgctttgagcctggctttcagcccttc
gtgttggtgcagtgtcagcccccggctgtggtcacctccttggccctgcactctgagtgg
cggctcgtggccttcggcaccagccatggctttggcctctttgaccaccagcagcggcgg
caggtctttgttaagtgcacactgcaccccagtgaccagctggccttggagggcccactc
tcccgcgtcaagtccctcaagaagtccttgcgtcagtcattccgccggatgcgtcggagc
cgggtgtccagccggaagcggcacccggctggccccccaggagaggcacaggaggggagt
gccaaggctgagcggccaggcctccagaacatggagctggcgcctgtgcagcgcaagatc
gaggctcgctcggcagaggactccttcacaggcttcgtccggaccctgtactttgctgac
acctacctgaaggacagctcccggcactgcccctcgctgtgggctggcaccaatgggggc
accatctatgccttctccctgcgtgtgcctcccgccgagcggagaatggatgagcctgtg
cgggcagagcaggccaaggagatccagctgatgcaccgggcgccggtggtgggcatcctg
gtgctcgacggacacagcgtaccccttcccgagcccctcgaagtggcccatgatctgtcg
aagagccctgacatgcagggaagccaccagctgctcgtcgtatcagaggagcagttcaag
gtgttcacgctgcccaaggtgagtgccaagctgaagttgaagctgacggccctggagggc
tcaagagtgcggcgggtcagcgtggcccacttcggcagtcgtcgagccgaggactacggg
gagcaccacctggcagtccttaccaacctgggcgacatccaggtggtctcgctgcccctg
ctcaagccccaggtgcgctacagctgcatccgccgggaggacgtcagtggcatcgcctcc
tgcgtcttcaccaaatatggccaaggcttctacctgatctcaccctcggagtttgagcgc
ttctctctctccaccaagtggctggtggagccccggtgtctggtggattcagcagaaacc
aagaaccaccgccctggtaacggtgcgggccccaagaaggccccgagccgagccaggaac
tcagggactcagagtgatggcgaggagaagcagcccggcctggtgatggagcgcgctctg
ctcagtgatgagagagtcctgaaggaaatccagagcacactggagggagaccgcgggagc
ggcaactggcgttcacatcgagccgccgtggggtgcagcctcagcaatggcggagcagag
tga
Homo sapiens (human): 23513
Help
Entry
23513 CDS
T01001
Symbol
SCRIB, CRIB1, SCRB1, SCRIB1, Vartul, oSCRIB
Name
(RefSeq) protein scribble homolog isoform a
KO
K16175
protein scribble
Organism
hsa
Homo sapiens (human)
Pathway
hsa04390
Hippo signaling pathway
hsa04530
Tight junction
hsa05165
Human papillomavirus infection
hsa05203
Viral carcinogenesis
Network
nt06166
Human papillomavirus (HPV)
Element
N00340
The Scribble/Dlg/Lgl polarity module
N00341
HPV E6 to the Scribble/Dlg/Lgl polarity module
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04390 Hippo signaling pathway
23513 (SCRIB)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04530 Tight junction
23513 (SCRIB)
09160 Human Diseases
09161 Cancer: overview
05203 Viral carcinogenesis
23513 (SCRIB)
09172 Infectious disease: viral
05165 Human papillomavirus infection
23513 (SCRIB)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDZ
PDZ_6
LRR_8
LRR_14
LRR_4
PDZ_2
LRR_LRWD1
PDZ_Tricorn
LRR_9
Pept_S41_N_bact
AbLIM_anchor
Motif
Other DBs
NCBI-GeneID:
23513
NCBI-ProteinID:
NP_874365
OMIM:
607733
HGNC:
30377
Ensembl:
ENSP00000349486.2
UniProt:
Q14160
A0A0G2JPP5
A0PJK8
Structure
PDB
PDBj
LinkDB
All DBs
Position
8:complement(143790925..143815773)
Genome browser
AA seq
1655 aa
AA seq
DB search
MLKCIPLWRCNRHVESVDKRHCSLQAVPEEIYRYSRSLEELLLDANQLRELPKPFFRLLN
LRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDIPEIPESIKFCKALEIADFSGNPLSRL
PDGFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPASLSFLVKLEQLD
LGGNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRLEELPAELG
GLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVTEAIGDCENLSELILTENL
LMALPRSLGKLTKLTNLNVDRNHLEALPPEIGGCVALSVLSLRDNRLAVLPPELAHTTEL
HVLDVAGNRLQSLPFALTHLNLKALWLAENQAQPMLRFQTEDDARTGEKVLTCYLLPQQP
PPSLEDAGQQGSLSETWSDAPPSRVSVIQFLEAPIGDEDAEEAAAEKRGLQRRATPHPSE
LKVMKRSIEGRRSEACPCQPDSGSPLPAEEEKRLSAESGLSEDSRPSASTVSEAEPEGPS
AEAQGGSQQEATTAGGEEDAEEDYQEPTVHFAEDALLPGDDREIEEGQPEAPWTLPGGRQ
RLIRKDTPHYKKHFKISKLPQPEAVVALLQGMQPDGEGPVAPGGWHNGPHAPWAPRAQKE
EEEEEEGSPQEEEEEEEEENRAEEEEASTEEEDKEGAVVSAPSVKGVSFDQANNLLIEPA
RIEEEELTLTILRQTGGLGISIAGGKGSTPYKGDDEGIFISRVSEEGPAARAGVRVGDKL
LEVNGVALQGAEHHEAVEALRGAGTAVQMRVWRERMVEPENAVTITPLRPEDDYSPRERR
GGGLRLPLLPPESPGPLRQRHVACLARSERGLGFSIAGGKGSTPYRAGDAGIFVSRIAEG
GAAHRAGTLQVGDRVLSINGVDVTEARHDHAVSLLTAASPTIALLLEREAGGPLPPSPLP
HSSPPTAAVATTSITTATPGVPGLPSLAPSLLAAALEGPYPVEEIRLPRAGGPLGLSIVG
GSDHSSHPFGVQEPGVFISKVLPRGLAARSGLRVGDRILAVNGQDVRDATHQEAVSALLR
PCLELSLLVRRDPAPPGLRELCIQKAPGERLGISIRGGARGHAGNPRDPTDEGIFISKVS
PTGAAGRDGRLRVGLRLLEVNQQSLLGLTHGEAVQLLRSVGDTLTVLVCDGFEASTDAAL
EVSPGVIANPFAAGIGHRNSLESISSIDRELSPEGPGKEKELPGQTLHWGPEATEAAGRG
LQPLKLDYRALAAVPSAGSVQRVPSGAAGGKMAESPCSPSGQQPPSPPSPDELPANVKQA
YRAFAAVPTSHPPEDAPAQPPTPGPAASPEQLSFRERQKYFELEVRVPQAEGPPKRVSLV
GADDLRKMQEEEARKLQQKRAQMLREAAEAGAEARLALDGETLGEEEQEDEQPPWASPSP
TSRQSPASPPPLGGGAPVRTAKAERRHQERLRVQSPEPPAPERALSPAELRALEAEKRAL
WRAARMKSLEQDALRAQMVLSRSQEGRGTRGPLERLAEAPSPAPTPSPTPVEDLGPQTST
SPGRLPLSGKKFDYRAFAALPSSRPVYDIQSPDFAEELRSLEPSPSPGPQEEDGEVALVL
LGRPSPGAVGPEDVALCSSRRPVRPGRRGLGPVPS
NT seq
4968 nt
NT seq
+upstream
nt +downstream
nt
atgctcaagtgcatcccgctgtggcgctgcaaccggcacgtggagtcggtggacaagcgg
cactgttcgctgcaggccgtgccggaggagatctaccgctacagccgcagcctggaggag
ctgctgctcgacgccaaccagctgcgcgagctgcccaagccttttttccggctgctgaac
ttgcgcaagctgggcctgagcgacaacgagatccagcggttgcctcccgaggtggccaac
ttcatgcagctggtggagctggacgtgtcccggaacgatatccctgagatcccggagagc
atcaagttctgcaaggctctggagatcgcggacttcagcgggaaccccctctccaggctc
cctgatggcttcactcagctgcgcagcctggctcacctggccctgaatgatgtgtctctg
caggcactgcccggggacgtgggcaacctcgccaacctggtgaccctggagctccgggag
aacctgctcaagtccctgccagcgtccctgtcatttctggtcaagctggaacagctggat
ctgggaggcaacgatctggaagtgctgccagacactctgggggctctgcccaatcttcgg
gagctgtggcttgaccggaaccagctgtcagcactgcccccggagctcgggaacctgcgg
cgcctggtgtgcctggacgtgtcggaaaaccggctggaggagctgcctgctgagctcggc
gggctggtgctgctcactgacctgctgctgtcccagaacctgctgcggaggctgcccgac
ggcatcggtcagctgaagcagctatccatcctaaaggtagaccagaatcggctgtgcgag
gtgaccgaggccatcggggactgtgagaacctctctgagctgatcctcacggagaacctg
ctgatggccctgccccgctccctgggaaagctgactaagctgaccaacctcaacgtggac
cggaaccacctcgaggcgctgccgcccgagatcgggggctgtgtggcactcagcgtcctc
tccttgagggacaaccgcctggccgtcctgccaccagagctggcccacacgacagagctg
cacgtgctggacgtggcggggaaccgcctgcagagtctgccgttcgcgctcacccacctc
aatctcaaggccctgtggctggcagagaaccaggcgcagcccatgctccggttccagacg
gaggatgatgcccggaccggcgagaaggtgctcacctgctacttgctgccccagcagccc
ccacccagcctcgaggatgctgggcagcaggggagcctctcggagacctggagcgatgcc
ccgccgagccgcgtcagcgtcatccagttcctggaggcccccataggtgatgaggacgct
gaggaagctgcagctgagaagcggggcctacagcgccgggccacacctcaccccagcgag
ctcaaggtgatgaagaggagcatcgaggggcggcggagcgaggcctgcccttgccagcca
gactctgggtcgcccttgcctgcagaggaggagaagcggctgagtgccgagtctggcctg
agtgaagactctcgcccatctgccagcacagtctctgaggctgagcccgagggcccgtcg
gctgaggcacagggtgggagccagcaggaagccacgactgctggcggggaggaagacgcc
gaagaggactaccaggagcccacggtgcatttcgcagaggacgcactgctgcccggggat
gacagggagatcgaggaggggcagcctgaggccccctggaccctgccaggcgggaggcag
cggctcatccgcaaggacacacctcactacaaaaagcacttcaagatctccaagctgccc
cagcccgaggccgttgtggctctgctgcagggcatgcagcctgatggggagggccctgtg
gctcccgggggctggcacaatggcccccacgcaccctgggctcctcgggcccagaaggag
gaggaggaggaggaagagggtagtcctcaggaggaggaggaagaggaggaggaggaaaac
agggctgaagaggaagaggccagcactgaggaggaggacaaggagggggccgtggtttct
gcgccctctgtcaagggagtgtcgtttgaccaggccaataacctgctgatagagcctgct
cgcattgaggaggaagagctgaccctcactatcctgcggcagactgggggcctgggcatc
agcattgcgggcggcaagggctccacaccctataagggggacgacgagggcatattcatc
tctcgggtgtccgaggaaggccctgcggcccgggctggagtccgtgtgggtgacaagctc
ctggaggtgaatggtgtggctctgcagggcgccgagcaccacgaggccgtggaggcgctc
cggggggccggcactgccgtgcagatgcgagtgtggcgggagcgcatggtggagcctgag
aacgcggtcaccatcacgccgctgcggcccgaggatgattacagcccccgagagcggcgg
ggaggggggctgcgcctgcccctgctcccgcctgagagccccgggcccctccgtcagcgc
cacgtggcctgcctggcacgcagcgagagggggctgggcttcagcattgctggtgggaaa
ggctccacaccctacagggctggtgatgcgggcatcttcgtctcccgcattgccgagggc
ggtgctgctcaccgcgcgggcacactgcaggttggcgaccgcgtcctctctattaatgga
gtggacgtgactgaggccaggcatgaccacgccgtctccctgctgaccgctgcctccccc
accatcgccctgctgttggagcgggaggctgggggccctcttcctcccagccctctgcca
cattcctcaccccccaccgctgctgttgccaccaccagcataaccactgccacccccggg
gtgcctgggttgccgagcctggcccccagcctgctggctgccgcgttggaagggccatac
ccagtggaggagatccgtctgccaagagctgggggccctctggggcttagtattgtcgga
ggctccgaccattccagccacccgtttggtgtccaggagcctggtgtgttcatctccaag
gtgctcccgcggggcctggccgctcgcagcggcctgcgggttggggaccgcatcctggca
gtgaacgggcaagacgtgcgggatgccacgcaccaagaagcagtcagtgccctgctccgg
ccctgcctggagctgtcgctgctggtgcggagggacccggcacccccgggcctacgggaa
ctgtgcatccagaaggcacctggggagaggctgggcatcagcatccgcgggggtgccagg
ggccacgctggcaacccccgcgaccccacagacgagggcatcttcatctccaaggtgagc
cccacgggggcagccgggcgcgacggtcggctgcgtgtgggtttgcggctgttggaggtg
aaccagcagagcctgctgggcctgacgcacggcgaggcggtgcagctgctccgcagtgtg
ggcgacaccctcaccgtgctggtctgtgacggctttgaggccagcaccgacgcagccctg
gaggtgtccccaggtgtcattgccaacccctttgcggcaggcatcggccaccggaacagc
ctggagagcatctcttccatcgaccgggagctgagccctgagggcccaggcaaggagaag
gagctgcctggacagaccctgcactgggggcccgaggccacagaagccgcaggtcggggt
ctgcagcccctgaagctggactaccgcgccctggccgccgtgcccagcgctggcagcgtg
cagagggtaccgtctggagcagctggagggaagatggctgaatctccctgctcccctagt
ggccagcagccgccctccccgccttctccggatgagctgcccgccaatgtgaagcaggcc
tacagggccttcgcggccgtgcccacttctcacccgcctgaggatgcccctgcccagccc
cccacgcctgggcctgcagcctccccggagcagctgtccttccgggagcggcagaagtac
tttgagctggaggtgcgcgtgccccaggccgagggcccccctaagcgcgtgtccctggtg
ggtgctgacgacctgcggaagatgcaggaggaggaagccagaaaactacagcagaagaga
gcgcagatgctgcgggaggcggcagaggctggggccgaagcgaggctcgccctggacggg
gagacgctgggcgaggaggaacaggaggatgagcagccaccctgggccagcccgagcccc
acctcaaggcagagcccggcgtcccccccacccctgggaggtggcgccccggtgcggacg
gccaaagctgaacggcgccaccaggagcggctgcgcgtgcagagtccggagccaccggca
cccgagcgtgccctgtcccctgccgagctccgggccctggaggccgagaagcgtgcgctg
tggagggcagccaggatgaagtcattggaacaggacgctctccgagcacagatggtcctc
agcaggtcccaggaaggccggggcacgcgggggcccctggagcgactggccgaggcccct
tcccctgcgcccaccccgtcgcccacccctgtggaagacctcggcccccagaccagcacc
tccccgggacgcctgcccttgtctggaaagaagtttgactacagggcctttgcggccctg
ccttcttccagacctgtctatgacatccagtcaccggactttgctgaggagttgaggtcc
ctggaaccatctcccagccctggcccgcaggaggaggatggagaagtggctctggtgctt
ctgggcaggccctcacccggcgctgtgggccctgaagatgtggcactgtgcagcagccgc
cgccccgtaaggcctgggcgccgtggcctgggccctgtgccctcctag
Homo sapiens (human): 1739
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Entry
1739 CDS
T01001
Symbol
DLG1, DLGH1, SAP-97, SAP97, hdlg
Name
(RefSeq) disks large homolog 1 isoform 1
KO
K12076
disks large protein 1
Organism
hsa
Homo sapiens (human)
Pathway
hsa04390
Hippo signaling pathway
hsa04530
Tight junction
hsa04660
T cell receptor signaling pathway
hsa05165
Human papillomavirus infection
hsa05166
Human T-cell leukemia virus 1 infection
hsa05203
Viral carcinogenesis
Network
nt06160
Human T-cell leukemia virus 1 (HTLV-1)
nt06166
Human papillomavirus (HPV)
nt06214
PI3K signaling (cancer)
nt06541
Cytoskeleton in neurons
Element
N00340
The Scribble/Dlg/Lgl polarity module
N00341
HPV E6 to the Scribble/Dlg/Lgl polarity module
N00502
HTLV-1 Tax to PTEN-PIP3-AKT signaling pathway
N01852
MYO6-mediated vesicle transport
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04390 Hippo signaling pathway
1739 (DLG1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04530 Tight junction
1739 (DLG1)
09150 Organismal Systems
09151 Immune system
04660 T cell receptor signaling pathway
1739 (DLG1)
09160 Human Diseases
09161 Cancer: overview
05203 Viral carcinogenesis
1739 (DLG1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
1739 (DLG1)
05165 Human papillomavirus infection
1739 (DLG1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
hsa03036
]
1739 (DLG1)
Chromosome and associated proteins [BR:
hsa03036
]
Eukaryotic type
Centrosome formation proteins
Other centrosome associated proteins
1739 (DLG1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Guanylate_kin
PDZ
MAGUK_N_PEST
L27_1
PDZ_assoc
PDZ_6
PDZ_2
SH3_1
SH3_2
SH3_9
Motif
Other DBs
NCBI-GeneID:
1739
NCBI-ProteinID:
NP_001091894
OMIM:
601014
HGNC:
2900
UniProt:
Q12959
Structure
PDB
PDBj
LinkDB
All DBs
Position
3:complement(197042560..197299321)
Genome browser
AA seq
904 aa
AA seq
DB search
MPVRKQDTQRALHLLEEYRSKLSQTEDRQLRSSIERVINIFQSNLFQALIDIQEFYEVTL
LDNPKCIDRSKPSEPIQPVNTWEISSLPSSTVTSETLPSSLSPSVEKYRYQDEDTPPQEH
ISPQITNEVIGPELVHVSEKNLSEIENVHGFVSHSHISPIKPTEAVLPSPPTVPVIPVLP
VPAENTVILPTIPQANPPPVLVNTDSLETPTYVNGTDADYEYEEITLERGNSGLGFSIAG
GTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEVDVRDVTHSKAVEALKEAG
SIVRLYVKRRKPVSEKIMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAH
KDGKLQIGDKLLAVNNVCLEEVTHEEAVTALKNTSDFVYLKVAKPTSMYMNDGYAPPDIT
NSSSQPVDNHVSPSSFLGQTPASPARYSPVSKAVLGDDEITREPRKVVLHRGSTGLGFNI
VGGEDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAVT
IVAQYRPEEYSRFEAKIHDLREQMMNSSISSGSGSLRTSQKRSLYVRALFDYDKTKDSGL
PSQGLNFKFGDILHVINASDDEWWQARQVTPDGESDEVGVIPSKRRVEKKERARLKTVKF
NSKTRDKGEIPDDMGSKGLKHVTSNASDSESSYRGQEEYVLSYEPVNQQEVNYTRPVIIL
GPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIE
AGQYNNHLYGTSVQSVREVAEKGKHCILDVSGNAIKRLQIAQLYPISIFIKPKSMENIME
MNKRLTEEQARKTFERAMKLEQEFTEHFTAIVQGDTLEDIYNQVKQIIEEQSGSYIWVPA
KEKL
NT seq
2715 nt
NT seq
+upstream
nt +downstream
nt
atgccggtccggaagcaagatacccagagagcattgcaccttttggaggaatatcgttca
aaactaagccaaactgaagacagacagctcagaagttccatagaacgggttattaacata
tttcagagcaacctctttcaggctttaatagatattcaagaattttatgaagtgacctta
ctggataatccaaaatgtatagatcgttcaaagccgtctgaaccaattcaacctgtgaat
acttgggagatttccagccttccaagctctactgtgacttcagagacactgccaagcagc
cttagccctagtgtagagaaatacaggtatcaggatgaagatacacctcctcaagagcat
atttccccacaaatcacaaatgaagtgataggtccagaattggttcatgtctcagagaag
aacttatcagagattgagaatgtccatggatttgtttctcattctcatatttcaccaata
aagccaacagaagctgttcttccctctcctcccactgtccctgtgatccctgtcctgcca
gtccctgctgagaatactgtcatcctacccaccataccacaggcaaatcctcccccagta
ctggtcaacacagatagcttggaaacaccaacttacgttaatggcacagatgcagattat
gaatatgaagaaatcacacttgaaaggggaaattcagggcttggtttcagcattgcagga
ggtacggacaacccacacattggagatgactcaagtattttcattaccaaaattatcaca
gggggagcagccgcccaagatggaagattgcgggtcaatgactgtatattacgagtaaat
gaagtagatgttcgtgatgtaacacatagcaaagcagttgaagcgttgaaagaagcaggg
tctattgtacgcttgtatgtaaaaagaaggaaaccagtgtcagaaaaaataatggaaata
aagctcattaaaggtcctaaaggtcttgggtttagcattgctggaggtgttggaaatcag
catattcctggggataatagcatctatgtaaccaaaataattgaaggaggtgcagcacat
aaggatggcaaacttcagattggagataaacttttagcagtgaataacgtatgtttagaa
gaagttactcatgaagaagcagtaactgccttaaagaacacatctgattttgtttatttg
aaagtggcaaaacccacaagtatgtatatgaatgatggctatgcaccacctgatatcacc
aactcttcttctcagcctgttgataaccatgttagcccatcttccttcttgggccagaca
ccagcatctccagccagatactccccagtttctaaagcagtacttggagatgatgaaatt
acaagggaacctagaaaagttgttcttcatcgtggctcaacgggccttggtttcaacatt
gtaggaggagaagatggagaaggaatatttatttcctttatcttagccggaggacctgct
gatctaagtggagagctcagaaaaggagatcgtattatatcggtaaacagtgttgacctc
agagctgctagtcatgagcaggcagcagctgcattgaaaaatgctggccaggctgtcaca
attgttgcacaatatcgacctgaagaatacagtcgttttgaagctaaaatacatgattta
cgggagcagatgatgaatagtagtattagttcagggtcaggttctcttcgaactagccag
aagcgatccctctatgtcagagccctttttgattatgacaagactaaagacagtgggctt
cccagtcagggactgaacttcaaatttggagatatcctccatgttattaatgcttctgat
gatgaatggtggcaagccaggcaggttacaccagatggtgagagcgatgaggtcggagtg
attcccagtaaacgcagagttgagaagaaagaacgagcccgattaaaaacagtgaaattc
aattctaaaacgagagataaaggggagatccctgacgacatgggatcaaaaggcctgaag
catgtaacttctaatgccagcgatagtgaaagtagttaccgtggtcaagaagaatacgtc
ttatcttatgaaccagtgaatcaacaagaagttaattatactcgaccagtgatcatattg
ggacctatgaaagacaggataaatgatgacttgatctcagaatttcctgacaaatttgga
tcctgtgttcctcatacaactagaccaaaacgagattatgaggtagatggaagagattat
cattttgtgacttcaagagagcagatggaaaaagatatccaggaacataaattcattgaa
gctggccagtataacaatcatctatatggaacaagtgttcagtctgtacgagaagtagca
gaaaagggcaaacactgtatccttgatgtgtctggaaatgccataaagagattacagatt
gcacagctttaccctatctccatttttattaaacccaaatccatggaaaatatcatggaa
atgaataagcgtctaacagaagaacaagccagaaaaacatttgagagagccatgaaactg
gaacaggagtttactgaacatttcacagctattgtacagggggatacgctggaagacatt
tacaaccaagtgaaacagatcatagaagaacaatctggttcttacatctgggttccggca
aaagaaaagctatga
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integrated database retrieval system
