Homo sapiens (human): 4018
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Entry
4018 CDS
T01001
Symbol
LPA, AK38, APOA, LP
Name
(RefSeq) lipoprotein(a)
KO
K09644
apolipoprotein(a) [EC:3.4.21.-]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04979
Cholesterol metabolism
Drug target
Muvalaplin:
D12460
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09154 Digestive system
04979 Cholesterol metabolism
4018 (LPA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
hsa01002
]
4018 (LPA)
Peptidases and inhibitors [BR:
hsa01002
]
Serine peptidases
Family S1: chymotrypsin family
4018 (LPA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Kringle
Trypsin
DUF1986
Trypsin_2
Motif
Other DBs
NCBI-GeneID:
4018
NCBI-ProteinID:
NP_005568
OMIM:
152200
HGNC:
6667
Ensembl:
ENSG00000198670
UniProt:
P08519
Structure
PDB
LinkDB
All DBs
Position
6:complement(160531482..160664275)
Genome browser
AA seq
2040 aa
AA seq
DB search
MEHKEVVLLLLLFLKSAAPEQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQH
NRTTENYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTP
VPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEY
YPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEA
PSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGL
IMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAP
TEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCR
NPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG
VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA
APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH
GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT
RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSY
RGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVR
WEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYST
TVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDPVAAPYCYTRDPSVRWEYCNL
TQCSDAEGTAVAPPTITPIPSLEAPSEQAPTEQRPGVQECYHGNGQSYQGTYFITVTGRT
CQAWSSMTPHSHSRTPAYYPNAGLIKNYCRNPDPVAAPWCYTTDPSVRWEYCNLTRCSDA
EWTAFVPPNVILAPSLEAFFEQALTEETPGVQDCYYHYGQSYRGTYSTTVTGRTCQAWSS
MTPHQHSRTPENYPNAGLTRNYCRNPDAEIRPWCYTMDPSVRWEYCNLTQCLVTESSVLA
TLTVVPDPSTEASSEEAPTEQSPGVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWH
QRTTEYYPNGGLTRNYCRNPDAEISPWCYTMDPNVRWEYCNLTQCPVTESSVLATSTAVS
EQAPTEQSPTVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTR
NYCRNPDAEIRPWCYTMDPSVRWEYCNLTQCPVMESTLLTTPTVVPVPSTELPSEEAPTE
NSTGVQDCYRGDGQSYRGTLSTTITGRTCQSWSSMTPHWHRRIPLYYPNAGLTRNYCRNP
DAEIRPWCYTMDPSVRWEYCNLTRCPVTESSVLTTPTVAPVPSTEAPSEQAPPEKSPVVQ
DCYHGDGRSYRGISSTTVTGRTCQSWSSMIPHWHQRTPENYPNAGLTENYCRNPDSGKQP
WCYTTDPCVRWEYCNLTQCSETESGVLETPTVVPVPSMEAHSEAAPTEQTPVVRQCYHGN
GQSYRGTFSTTVTGRTCQSWSSMTPHRHQRTPENYPNDGLTMNYCRNPDADTGPWCFTMD
PSIRWEYCNLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCMFGNGKGYRGKKATTVTGTP
CQEWAAQEPHRHSTFIPGTNKWAGLEKNYCRNPDGDINGPWCYTMNPRKLFDYCDIPLCA
SSSFDCGKPQVEPKKCPGSIVGGCVAHPHSWPWQVSLRTRFGKHFCGGTLISPEWVLTAA
HCLKKSSRPSSYKVILGAHQEVNLESHVQEIEVSRLFLEPTQADIALLKLSRPAVITDKV
MPACLPSPDYMVTARTECYITGWGETQGTFGTGLLKEAQLLVIENEVCNHYKYICAEHLA
RGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYARVSRFVTWIEGMMRNN
NT seq
6123 nt
NT seq
+upstream
nt +downstream
nt
atggaacataaggaagtggttcttctacttcttttatttctgaaatcagcagcacctgag
caaagccatgtggtccaggattgctaccatggtgatggacagagttatcgaggcacgtac
tccaccactgtcacaggaaggacctgccaagcttggtcatctatgacaccacatcaacat
aataggaccacagaaaactacccaaatgctggcttgatcatgaactactgcaggaatcca
gatgctgtggcagctccttattgttatacgagggatcccggtgtcaggtgggagtactgc
aacctgacgcaatgctcagacgcagaagggactgccgtcgcgcctccgactgttaccccg
gttccaagcctagaggctccttccgaacaagcaccgactgagcaaaggcctggggtgcag
gagtgctaccatggtaatggacagagttatcgaggcacatactccaccactgtcacagga
agaacctgccaagcttggtcatctatgacaccacactcgcatagtcggaccccagaatac
tacccaaatgctggcttgatcatgaactactgcaggaatccagatgctgtggcagctcct
tattgttatacgagggatcccggtgtcaggtgggagtactgcaacctgacgcaatgctca
gacgcagaagggactgccgtcgcgcctccgactgttaccccggttccaagcctagaggct
ccttccgaacaagcaccgactgagcaaaggcctggggtgcaggagtgctaccatggtaat
ggacagagttatcgaggcacatactccaccactgtcacaggaagaacctgccaagcttgg
tcatctatgacaccacactcgcatagtcggaccccagaatactacccaaatgctggcttg
atcatgaactactgcaggaatccagatgctgtggcagctccttattgttatacgagggat
cccggtgtcaggtgggagtactgcaacctgacgcaatgctcagacgcagaagggactgcc
gtcgcgcctccgactgttaccccggttccaagcctagaggctccttccgaacaagcaccg
actgagcagaggcctggggtgcaggagtgctaccacggtaatggacagagttatcgaggc
acatactccaccactgtcactggaagaacctgccaagcttggtcatctatgacaccacac
tcgcatagtcggaccccagaatactacccaaatgctggcttgatcatgaactactgcagg
aatccagatgctgtggcagctccttattgttatacgagggatcccggtgtcaggtgggag
tactgcaacctgacgcaatgctcagacgcagaagggactgccgtcgcgcctccgactgtt
accccggttccaagcctagaggctccttccgaacaagcaccgactgagcaaaggcctggg
gtgcaggagtgctaccatggtaatggacagagttatcgaggcacatactccaccactgtc
acaggaagaacctgccaagcttggtcatctatgacaccacactcgcatagtcggacccca
gaatactacccaaatgctggcttgatcatgaactactgcaggaatccagatgctgtggca
gctccttattgttatacgagggatcccggtgtcaggtgggagtactgcaacctgacgcaa
tgctcagacgcagaagggactgccgtcgcgcctccgactgttaccccggttccaagccta
gaggctccttccgaacaagcaccgactgagcaaaggcctggggtgcaggagtgctaccat
ggtaatggacagagttatcgaggcacatactccaccactgtcacaggaagaacctgccaa
gcttggtcatctatgacaccacactcgcatagtcggaccccagaatactacccaaatgct
ggcttgatcatgaactactgcaggaatccagatgctgtggcagctccttattgttatacg
agggatcccggtgtcaggtgggagtactgcaacctgacgcaatgctcagacgcagaaggg
actgccgtcgcgcctccgactgttaccccggttccaagcctagaggctccttccgaacaa
gcaccgactgagcaaaggcctggggtgcaggagtgctaccatggtaatggacagagttat
cgaggcacatactccaccactgtcacaggaagaacctgccaagcttggtcatctatgaca
ccacactcgcatagtcggaccccagaatactacccaaatgctggcttgatcatgaactac
tgcaggaatccagatgctgtggcagctccttattgttatacgagggatcccggtgtcagg
tgggagtactgcaacctgacgcaatgctcagacgcagaagggactgccgtcgcgcctccg
actgttaccccggttccaagcctagaggctccttccgaacaagcaccgactgagcagagg
cctggggtgcaggagtgctaccacggtaatggacagagttatcgaggcacatactccacc
actgtcactggaagaacctgccaagcttggtcatctatgacaccacactcgcatagtcgg
accccagaatactacccaaatgctggcttgatcatgaactactgcaggaatccagatcct
gtggcagccccttattgttatacgagggatcccagtgtcaggtgggagtactgcaacctg
acacaatgctcagacgcagaagggactgccgtcgcgcctccaactattaccccgattcca
agcctagaggctccttctgaacaagcaccaactgagcaaaggcctggggtgcaggagtgc
taccacggaaatggacagagttatcaaggcacatacttcattactgtcacaggaagaacc
tgccaagcttggtcatctatgacaccacactcgcatagtcggaccccagcatactaccca
aatgctggcttgatcaagaactactgccgaaatccagatcctgtggcagccccttggtgt
tatacaacagatcccagtgtcaggtgggagtactgcaacctgacacgatgctcagatgca
gaatggactgccttcgtccctccgaatgttattctggctccaagcctagaggcttttttt
gaacaagcactgactgaggaaacccccggggtacaggactgctactaccattatggacag
agttaccgaggcacatactccaccactgtcacaggaagaacttgccaagcttggtcatct
atgacaccacaccagcatagtcggaccccagaaaactacccaaatgctggcctgaccagg
aactactgcaggaatccagatgctgagattcgcccttggtgttacaccatggatcccagt
gtcaggtgggagtactgcaacctgacacaatgcctggtgacagaatcaagtgtccttgca
actctcacggtggtcccagatccaagcacagaggcttcttctgaagaagcaccaacggag
caaagccccggggtccaggattgctaccatggtgatggacagagttatcgaggctcattc
tctaccactgtcacaggaaggacatgtcagtcttggtcctctatgacaccacactggcat
cagaggacaacagaatattatccaaatggtggcctgaccaggaactactgcaggaatcca
gatgctgagattagtccttggtgttataccatggatcccaatgtcagatgggagtactgc
aacctgacacaatgtccagtgacagaatcaagtgtccttgcgacgtccacggctgtttct
gaacaagcaccaacggagcaaagccccacagtccaggactgctaccatggtgatggacag
agttatcgaggctcattctccaccactgttacaggaaggacatgtcagtcttggtcctct
atgacaccacactggcatcagagaaccacagaatactacccaaatggtggcctgaccagg
aactactgcaggaatccagatgctgagattcgcccttggtgttataccatggatcccagt
gtcagatgggagtactgcaacctgacgcaatgtccagtgatggaatcaactctcctcaca
actcccacggtggtcccagttccaagcacagagcttccttctgaagaagcaccaactgaa
aacagcactggggtccaggactgctaccgaggtgatggacagagttatcgaggcacactc
tccaccactatcacaggaagaacatgtcagtcttggtcgtctatgacaccacattggcat
cggaggatcccattatactatccaaatgctggcctgaccaggaactactgcaggaatcca
gatgctgagattcgcccttggtgttacaccatggatcccagtgtcaggtgggagtactgc
aacctgacacgatgtccagtgacagaatcgagtgtcctcacaactcccacagtggccccg
gttccaagcacagaggctccttctgaacaagcaccacctgagaaaagccctgtggtccag
gattgctaccatggtgatggacggagttatcgaggcatatcctccaccactgtcacagga
aggacctgtcaatcttggtcatctatgataccacactggcatcagaggaccccagaaaac
tacccaaatgctggcctgaccgagaactactgcaggaatccagattctgggaaacaaccc
tggtgttacacaaccgatccgtgtgtgaggtgggagtactgcaatctgacacaatgctca
gaaacagaatcaggtgtcctagagactcccactgttgttccagttccaagcatggaggct
cattctgaagcagcaccaactgagcaaacccctgtggtccggcagtgctaccatggtaat
ggccagagttatcgaggcacattctccaccactgtcacaggaaggacatgtcaatcttgg
tcatccatgacaccacaccggcatcagaggaccccagaaaactacccaaatgatggcctg
acaatgaactactgcaggaatccagatgccgatacaggcccttggtgttttaccatggac
cccagcatcaggtgggagtactgcaacctgacgcgatgctcagacacagaagggactgtg
gtcgctcctccgactgtcatccaggttccaagcctagggcctccttctgaacaagactgt
atgtttgggaatgggaaaggataccggggcaagaaggcaaccactgttactgggacgcca
tgccaggaatgggctgcccaggagccccatagacacagcacgttcattccagggacaaat
aaatgggcaggtctggaaaaaaattactgccgtaaccctgatggtgacatcaatggtccc
tggtgctacacaatgaatccaagaaaactttttgactactgtgatatccctctctgtgca
tcctcttcatttgattgtgggaagcctcaagtggagccgaagaaatgtcctggaagcatt
gtaggggggtgtgtggcccacccacattcctggccctggcaagtcagtctcagaacaagg
tttggaaagcacttctgtggaggcaccttaatatccccagagtgggtgctgactgctgct
cactgcttgaagaagtcctcaaggccttcatcctacaaggtcatcctgggtgcacaccaa
gaagtgaacctcgaatctcatgttcaggaaatagaagtgtctaggctgttcttggagccc
acacaagcagatattgccttgctaaagctaagcaggcctgccgtcatcactgacaaagta
atgccagcttgtctgccatccccagactacatggtcaccgccaggactgaatgttacatc
actggctggggagaaacccaaggtacctttgggactggccttctcaaggaagcccagctc
cttgttattgagaatgaagtgtgcaatcactataagtatatttgtgctgagcatttggcc
agaggcactgacagttgccagggtgacagtggagggcctctggtttgcttcgagaaggac
aaatacattttacaaggagtcacttcttggggtcttggctgtgcacgccccaataagcct
ggtgtctatgctcgtgtttcaaggtttgttacttggattgagggaatgatgagaaataat
taa
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integrated database retrieval system