Homo sapiens (human): 4038
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Entry
4038 CDS
T01001
Symbol
LRP4, CLSS, CMS17, LRP-4, LRP10, MEGF7, SOST2
Name
(RefSeq) low-density lipoprotein receptor-related protein 4 precursor
KO
K20051
low-density lipoprotein receptor-related protein 4
Organism
hsa
Homo sapiens (human)
Network
nt06505
WNT signaling
Element
N01441
Wnt signaling modulation, SOST/LRP4
Disease
H00486
Sclerosteosis
H00770
Congenital myasthenic syndrome
H00853
Cenani-Lenz syndactyly syndrome
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
4038 (LRP4)
Membrane trafficking [BR:
hsa04131
]
Endocytosis
Clathrin-mediated endocytosis
Low-density lipoprotein receptor (LDLR) family proteins
4038 (LRP4)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ldl_recept_b
Ldl_recept_a
FXa_inhibition
Vgb_lyase
SGL
cEGF
LRP1-like_beta_prop
EGF_LRP2
EGF_CA
Motif
Other DBs
NCBI-GeneID:
4038
NCBI-ProteinID:
NP_002325
OMIM:
604270
HGNC:
6696
Ensembl:
ENSP00000367888.1
UniProt:
O75096
Structure
PDB
PDBj
LinkDB
All DBs
Position
11:complement(46856717..46918550)
Genome browser
AA seq
1905 aa
AA seq
DB search
MRRQWGALLLGALLCAHGLASSPECACGRSHFTCAVSALGECTCIPAQWQCDGDNDCGDH
SDEDGCILPTCSPLDFHCDNGKCIRRSWVCDGDNDCEDDSDEQDCPPRECEEDEFPCQNG
YCIRSLWHCDGDNDCGDNSDEQCDMRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEE
NCPSAVPAPPCNLEEFQCAYGRCILDIYHCDGDDDCGDWSDESDCSSHQPCRSGEFMCDS
GLCINAGWRCDGDADCDDQSDERNCTTSMCTAEQFRCHSGRCVRLSWRCDGEDDCADNSD
EENCENTGSPQCALDQFLCWNGRCIGQRKLCNGVNDCGDNSDESPQQNCRPRTGEENCNV
NNGGCAQKCQMVRGAVQCTCHTGYRLTEDGHTCQDVNECAEEGYCSQGCTNSEGAFQCWC
ETGYELRPDRRSCKALGPEPVLLFANRIDIRQVLPHRSEYTLLLNNLENAIALDFHHRRE
LVFWSDVTLDRILRANLNGSNVEEVVSTGLESPGGLAVDWVHDKLYWTDSGTSRIEVANL
DGAHRKVLLWQNLEKPRAIALHPMEGTIYWTDWGNTPRIEASSMDGSGRRIIADTHLFWP
NGLTIDYAGRRMYWVDAKHHVIERANLDGSHRKAVISQGLPHPFAITVFEDSLYWTDWHT
KSINSANKFTGKNQEIIRNKLHFPMDIHTLHPQRQPAGKNRCGDNNGGCTHLCLPSGQNY
TCACPTGFRKISSHACAQSLDKFLLFARRMDIRRISFDTEDLSDDVIPLADVRSAVALDW
DSRDDHVYWTDVSTDTISRAKWDGTGQEVVVDTSLESPAGLAIDWVTNKLYWTDAGTDRI
EVANTDGSMRTVLIWENLDRPRDIVVEPMGGYMYWTDWGASPKIERAGMDASGRQVIISS
NLTWPNGLAIDYGSQRLYWADAGMKTIEFAGLDGSKRKVLIGSQLPHPFGLTLYGERIYW
TDWQTKSIQSADRLTGLDRETLQENLENLMDIHVFHRRRPPVSTPCAMENGGCSHLCLRS
PNPSGFSCTCPTGINLLSDGKTCSPGMNSFLIFARRIDIRMVSLDIPYFADVVVPINITM
KNTIAIGVDPQEGKVYWSDSTLHRISRANLDGSQHEDIITTGLQTTDGLAVDAIGRKVYW
TDTGTNRIEVGNLDGSMRKVLVWQNLDSPRAIVLYHEMGFMYWTDWGENAKLERSGMDGS
DRAVLINNNLGWPNGLTVDKASSQLLWADAHTERIEAADLNGANRHTLVSPVQHPYGLTL
LDSYIYWTDWQTRSIHRADKGTGSNVILVRSNLPGLMDMQAVDRAQPLGFNKCGSRNGGC
SHLCLPRPSGFSCACPTGIQLKGDGKTCDPSPETYLLFSSRGSIRRISLDTSDHTDVHVP
VPELNNVISLDYDSVDGKVYYTDVFLDVIRRADLNGSNMETVIGRGLKTTDGLAVDWVAR
NLYWTDTGRNTIEASRLDGSCRKVLINNSLDEPRAIAVFPRKGYLFWTDWGHIAKIERAN
LDGSERKVLINTDLGWPNGLTLDYDTRRIYWVDAHLDRIESADLNGKLRQVLVSHVSHPF
ALTQQDRWIYWTDWQTKSIQRVDKYSGRNKETVLANVEGLMDIIVVSPQRQTGTNACGVN
NGGCTHLCFARASDFVCACPDEPDSRPCSLVPGLVPPAPRATGMSEKSPVLPNTPPTTLY
SSTTRTRTSLEEVEGRCSERDARLGLCARSNDAVPAAPGEGLHISYAIGGLLSILLILVV
IAALMLYRHKKSKFTDPGMGNLTYSNPSYRTSTQEVKIEAIPKPAMYNQLCYKKEGGPDH
NYTKEKIKIVEGICLLSGDDAEWDDLKQLRSSRGGLLRDHVCMKTDTVSIQASSGSLDDT
ETEQLLQEEQSECSSVHTAATPERRGSLPDTGWKHERKLSSESQV
NT seq
5718 nt
NT seq
+upstream
nt +downstream
nt
atgaggcggcagtggggcgcgctgctgcttggcgccctgctctgcgcacacggcctggcc
agcagccccgagtgtgcttgtggtcggagccacttcacatgtgcagtgagtgctcttgga
gagtgtacctgcatccctgcccagtggcagtgtgatggagacaatgactgcggggaccac
agcgatgaggatggatgtatactacctacctgttcccctcttgactttcactgtgacaat
ggcaagtgcatccgccgctcctgggtgtgtgacggggacaacgactgtgaggatgactcg
gatgagcaggactgtcccccccgggagtgtgaggaggacgagtttccctgccagaatggc
tactgcatccggagtctgtggcactgcgatggtgacaatgactgtggcgacaacagcgat
gagcagtgtgacatgcgcaagtgctccgacaaggagttccgctgtagtgacggaagctgc
attgctgagcattggtactgcgacggtgacaccgactgcaaagatggctccgatgaggag
aactgtccctcagcagtgccagcgcccccctgcaacctggaggagttccagtgtgcctat
ggacgctgcatcctcgacatctaccactgcgatggcgacgatgactgtggagactggtca
gacgagtctgactgctcctcccaccagccctgccgctctggggagttcatgtgtgacagt
ggcctgtgcatcaatgcaggctggcgctgcgatggtgacgcggactgtgatgaccagtct
gatgagcgcaactgcaccacctccatgtgtacggcagaacagttccgctgtcactcaggc
cgctgtgtccgcctgtcctggcgctgtgatggggaggacgactgtgcagacaacagcgat
gaagagaactgtgagaatacaggaagcccccaatgtgccttggaccagttcctgtgttgg
aatgggcgctgcattgggcagaggaagctgtgcaacggggtcaacgactgtggtgacaac
agcgacgaaagcccacagcagaattgccggccccggacgggtgaggagaactgcaatgtt
aacaacggtggctgtgcccagaagtgccagatggtgcggggggcagtgcagtgtacctgc
cacacaggctaccggctcacagaggatgggcacacgtgccaagatgtgaatgaatgtgcc
gaggaggggtattgcagccagggctgcaccaacagcgaaggggctttccaatgctggtgt
gaaacaggctatgaactacggcccgaccggcgcagctgcaaggctctggggccagagcct
gtgctgctgttcgccaatcgcatcgacatccggcaggtgctgccacaccgctctgagtac
acactgctgcttaacaacctggagaatgccattgcccttgatttccaccaccgccgcgag
cttgtcttctggtcagatgtcaccctggaccggatcctccgtgccaacctcaacggcagc
aacgtggaggaggttgtgtctactgggctggagagcccagggggcctggctgtggattgg
gtccatgacaaactctactggaccgactcaggcacctcgaggattgaggtggccaatctg
gatggggcccaccggaaagtgttgctgtggcagaacctggagaagccccgggccattgcc
ttgcatcccatggagggtaccatttactggacagactggggcaacaccccccgtattgag
gcctccagcatggatggctctggacgccgcatcattgccgatacccatctcttctggccc
aatggcctcaccatcgactatgccgggcgccgtatgtactgggtggatgctaagcaccat
gtcatcgagagggccaatctggatgggagtcaccgtaaggctgtcattagccagggcctc
ccgcatcccttcgccatcacagtgtttgaagacagcctgtactggacagactggcacacc
aagagcatcaatagcgctaacaaatttacggggaagaaccaggaaatcattcgcaacaaa
ctccacttccctatggacatccacaccttgcacccccagcgccaacctgcagggaaaaac
cgctgtggggacaacaacggaggctgcacgcacctgtgtctgcccagtggccagaactac
acctgtgcctgccccactggcttccgcaagatcagcagccacgcctgtgcccagagtctt
gacaagttcctgctttttgcccgaaggatggacatccgtcgaatcagctttgacacagag
gacctgtctgatgatgtcatcccactggctgacgtgcgcagtgctgtggcccttgactgg
gactcccgggatgaccacgtgtactggacagatgtcagcactgataccatcagcagggcc
aagtgggatggaacaggacaggaggtggtagtggataccagtttggagagcccagctggc
ctggccattgattgggtcaccaacaaactgtactggacagatgcaggtacagaccggatt
gaagtagccaacacagatggcagcatgagaacagtactcatctgggagaaccttgatcgt
cctcgggacatcgtggtggaacccatgggcgggtacatgtattggactgactggggtgcg
agccccaagattgaacgagctggcatggatgcctcaggccgccaagtcattatctcttct
aatctgacctggcctaatgggttagctattgattatgggtcccagcgtctatactgggct
gacgccggcatgaagacaattgaatttgctggactggatggcagtaagaggaaggtgctg
attggaagccagctcccccacccatttgggctgaccctctatggagagcgcatctattgg
actgactggcagaccaagagcatacagagcgctgaccggctgacagggctggaccgggag
actctgcaggagaacctggaaaacctaatggacatccatgtcttccaccgccgccggccc
ccagtgtctacaccatgtgctatggagaatggcggctgtagccacctgtgtcttaggtcc
ccaaatccaagcggattcagctgtacctgccccacaggcatcaacctgctgtctgatggc
aagacctgctcaccaggcatgaacagtttcctcatcttcgccaggaggatagacattcgc
atggtctccctggacatcccttattttgctgatgtggtggtaccaatcaacattaccatg
aagaacaccattgccattggagtagacccccaggaaggaaaggtgtactggtctgacagc
acactgcacaggatcagtcgtgccaatctggatggctcacagcatgaggacatcatcacc
acagggctacagaccacagatgggctcgcggttgatgccattggccggaaagtatactgg
acagacacgggaacaaaccggattgaagtgggcaacctggacgggtccatgcggaaagtg
ttggtgtggcagaaccttgacagtccccgggccatcgtactgtaccatgagatggggttt
atgtactggacagactggggggagaatgccaagttagagcggtccggaatggatggctca
gaccgcgcggtgctcatcaacaacaacctaggatggcccaatggactgactgtggacaag
gccagctcccaactgctatgggccgatgcccacaccgagcgaattgaggctgctgacctg
aatggtgccaatcggcatacattggtgtcaccggtgcagcacccatatggcctcaccctg
ctcgactcctatatctactggactgactggcagactcggagcatccaccgtgctgacaag
ggtactggcagcaatgtcatcctcgtgaggtccaacctgccaggcctcatggacatgcag
gctgtggaccgggcacagccactaggttttaacaagtgcggctcgagaaatggcggctgc
tcccacctctgcttgcctcggccttctggcttctcctgtgcctgccccactggcatccag
ctgaagggagatgggaagacctgtgatccctctcctgagacctacctgctcttctccagc
cgtggctccatccggcgtatctcactggacaccagtgaccacaccgatgtgcatgtccct
gttcctgagctcaacaatgtcatctccctggactatgacagcgtggatggaaaggtctat
tacacagatgtgttcctggatgttatcaggcgagcagacctgaacggcagcaacatggag
acagtgatcgggcgagggctgaagaccactgacgggctggcagtggactgggtggccagg
aacctgtactggacagacacaggtcgaaataccattgaggcgtccaggctggatggttcc
tgccgcaaagtactgatcaacaatagcctggatgagccccgggccattgctgttttcccc
aggaaggggtacctcttctggacagactggggccacattgccaagatcgaacgggcaaac
ttggatggttctgagcggaaggtcctcatcaacacagacctgggttggcccaatggcctt
accctggactatgatacccgcaggatctactgggtggatgcgcatctggaccggatcgag
agtgctgacctcaatgggaaactgcggcaggtcttggtcagccatgtgtcccaccccttt
gccctcacacagcaagacaggtggatctactggacagactggcagaccaagtcaatccag
cgtgttgacaaatactcaggccggaacaaggagacagtgctggcaaatgtggaaggactc
atggatatcatcgtggtttcccctcagcggcagacagggaccaatgcctgtggtgtgaac
aatggtggctgcacccacctctgctttgccagagcctcggacttcgtatgtgcctgtcct
gacgaacctgatagccggccctgctcccttgtgcctggcctggtaccaccagctcctagg
gctactggcatgagtgaaaagagcccagtgctacccaacacaccacctaccaccttgtat
tcttcaaccacccggacccgcacgtctctggaggaggtggaaggaagatgctctgaaagg
gatgccaggctgggcctctgtgcacgttccaatgacgctgttcctgctgctccaggggaa
ggacttcatatcagctacgccattggtggactcctcagtattctgctgattttggtggtg
attgcagctttgatgctgtacagacacaaaaaatccaagttcactgatcctggaatgggg
aacctcacctacagcaacccctcctaccgaacatccacacaggaagtgaagattgaagca
atccccaaaccagccatgtacaaccagctgtgctataagaaagagggagggcctgaccat
aactacaccaaggagaagatcaagatcgtagagggaatctgcctcctgtctggggatgat
gctgagtgggatgacctcaagcaactgcgaagctcacgggggggcctcctccgggatcat
gtatgcatgaagacagacacggtgtccatccaggccagctctggctccctggatgacaca
gagacggagcagctgttacaggaagagcagtctgagtgtagcagcgtccatactgcagcc
actccagaaagacgaggctctctgccagacacgggctggaaacatgaacgcaagctctcc
tcagagagccaggtctaa
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integrated database retrieval system
