Homo sapiens (human): 4058
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Entry
4058 CDS
T01001
Symbol
LTK, TYK1
Name
(RefSeq) leukocyte receptor tyrosine kinase
KO
K05118
leukocyte tyrosine kinase [EC:
2.7.10.1
]
Organism
hsa
Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
4058 (LTK)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
4058 (LTK)
Protein kinases [BR:
hsa01001
]
Receptor tyrosine kinases (RTK)
ALK family
4058 (LTK)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
ALK_LTK_GRD
cEGF
FXa_inhibition
Motif
Other DBs
NCBI-GeneID:
4058
NCBI-ProteinID:
NP_002335
OMIM:
151520
HGNC:
6721
Ensembl:
ENSG00000062524
UniProt:
P29376
Structure
PDB
PDBj
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All DBs
Position
15:complement(41503637..41513827)
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AA seq
864 aa
AA seq
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MGCWGQLLVWFGAAGAILCSSPGSQETFLRSSPLPLASPSPRDPKVSAPPSILEPASPLN
SPGTEGSWLFSTCGASGRHGPTQTQCDGAYAGTSVVVTVGAAGQLRGVQLWRVPGPGQYL
ISAYGAAGGKGAKNHLSRAHGVFVSAIFSLGLGESLYILVGQQGEDACPGGSPESQLVCL
GESRAVEEHAAMDGSEGVPGSRRWAGGGGGGGGATYVFRVRAGELEPLLVAAGGGGRAYL
RPRDRGRTQASPEKLENRSEAPGSGGRGGAAGGGGGWTSRAPSPQAGRSLQEGAEGGQGC
SEAWATLGWAAAGGFGGGGGACTAGGGGGGYRGGDASETDNLWADGEDGVSFIHPSSELF
LQPLAVTENHGEVEIRRHLNCSHCPLRDCQWQAELQLAECLCPEGMELAVDNVTCMDLHK
PPGPLVLMVAVVATSTLSLLMVCGVLILVKQKKWQGLQEMRLPSPELELSKLRTSAIRTA
PNPYYCQVGLGPAQSWPLPPGVTEVSPANVTLLRALGHGAFGEVYEGLVIGLPGDSSPLQ
VAIKTLPELCSPQDELDFLMEALIISKFRHQNIVRCVGLSLRATPRLILLELMSGGDMKS
FLRHSRPHLGQPSPLVMRDLLQLAQDIAQGCHYLEENHFIHRDIAARNCLLSCAGPSRVA
KIGDFGMARDIYRASYYRRGDRALLPVKWMPPEAFLEGIFTSKTDSWSFGVLLWEIFSLG
YMPYPGRTNQEVLDFVVGGGRMDPPRGCPGPVYRIMTQCWQHEPELRPSFASILERLQYC
TQDPDVLNSLLPMELGPTPEEEGTSGLGNRSLECLRPPQPQELSPEKLKSWGGSPLGPWL
SSGLKPLKSRGLQPQNLWNPTYRS
NT seq
2595 nt
NT seq
+upstream
nt +downstream
nt
atgggctgctggggacagctgctggtgtggttcggagccgcgggcgccattctctgctct
agcccggggtcccaggagacttttctgcggtcctcgcccctgccgctggcaagtcccagc
ccccgggacccgaaagtcagcgccccgcctagtatcttggagccagcctccccgctgaat
tctccgggcaccgaggggtcttggctgttttctacctgcggggccagcggccggcatggg
cccacacagacacaatgtgacggggcgtacgcggggaccagcgtggtggtgaccgtgggg
gccgccgggcagctgagaggcgtgcagctgtggcgcgtgccgggccctggccagtatctg
atctcagcctacggagccgcgggcggcaaaggcgccaagaaccacctgtcgcgggcgcat
ggcgtcttcgtctcagcaatcttctccctcggtctcggggagtcgctgtacatcctggtg
gggcagcagggagaggacgcctgtcccggaggtagcccggagagccagctcgtctgcctc
ggggagtctcgagccgttgaagagcacgcggcgatggatgggagcgaaggggtcccgggg
tcgcggcgctgggcgggaggtggcgggggtggcgggggcgccacctacgttttccgggtg
cgcgctggcgagctggaaccgttgctggtggcggccggaggcggcggtcgggcctacctg
aggccgcgggaccgaggccggactcaggcctcccccgagaaactggagaaccgctcggag
gcgcccgggagcggcgggagaggcggggcggcaggtggtgggggcggctggacgtcgcgg
gctccctctccgcaggccggccgctcactgcaggagggggcggagggcggccagggctgc
tccgaggcttgggcgacccttggctgggccgcggccggcggcttcgggggcggcggcggg
gcctgcactgcgggcggaggcggcggcggctacagggggggcgacgcttcagagactgac
aacctctgggctgatggggaagatggagtatccttcatacaccccagcagcgagctcttc
ctgcagcctctggcagtcaccgagaaccacggagaggtagagatccgaaggcacctcaac
tgcagtcactgccctttgagagactgccaatggcaggcagagctccagctggctgaatgc
ctgtgcccagaaggcatggagctagctgtggataacgtcacctgcatggacctgcacaag
cccccaggccctctggttctgatggtggctgtggtggcaacctcaacactgagcctcctt
atggtgtgtggggtcctgattctggtgaagcagaagaagtggcagggcctgcaggagatg
aggctgccgagccctgagcttgagctgagcaagcttcgaacctctgccatcaggacagcc
cccaatccctattattgccaggtggggcttggcccggcccagtcctggcctctgccacca
ggtgtcaccgaggtttccccagccaatgttactctgctcagagccctgggccatggtgcc
tttggggaggtgtatgagggactggtaattggccttcctggggactccagtcccctgcag
gtagctatcaagaccctgccagaactctgctcgcctcaggatgagctggatttcctcatg
gaggccctcatcatcagcaagtttcgccatcagaacattgtgcggtgtgtggggctcagc
ctcagggccacccctcgcctcattctgctggaactgatgtctggaggggacatgaagagt
ttcctgaggcacagtcggccacacctgggccagccatcacctctggtcatgcgggacctg
ctgcaactggcccaggacatagcccagggctgccactacctggaggaaaatcacttcatc
cacagggatattgccgcccggaactgcctgctgagctgcgctggacccagccgagtggcc
aagattggggactttgggatggcacgagatatctaccgggccagttattaccgcaggggg
gaccgggccttgctcccagtcaagtggatgcccccagaggccttcctggagggcatcttc
acatccaagacagattcctggtcttttggggtgctgctctgggagatcttctcactgggc
tacatgccctatcctgggcgcaccaaccaggaggtgctggacttcgtcgttggaggaggc
cggatggaccctcctaggggctgcccagggcctgtgtaccgcatcatgacccagtgttgg
cagcacgagcctgagctccgccctagctttgccagcatcttggagcgtctgcagtactgc
actcaggacccggatgtgctgaattcactcctgccaatggagctggggcccaccccagag
gaggaagggacttctgggctggggaacagatctttggagtgcctaagacccccacagccc
caggaactgagtccagagaagttgaaaagctggggaggtagccctcttggcccctggctg
tcctctggcctcaagcccctcaaatccaggggcctccaacctcagaacctttggaatccc
acttatcgctcctga
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