| Entry |
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| Symbol |
IGF2R, CD222, CI-M6PR, CIMPR, M6P-R, M6P/IGF2R, MPR 300, MPR1, MPR300, MPRI
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| Name |
(RefSeq) cation-independent mannose-6-phosphate receptor precursor
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| KO |
| K06564 | insulin-like growth factor 2 receptor |
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| Organism |
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| Pathway |
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| Network |
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| Element |
| N02014 | M6P modification of lysosomal enzyme (LE) and binding to M6P-specific receptors |
| N02015 | Lysosomal enzyme (LE) transport from the TGN to endosome |
| N02017 | Retrieval of the lysosomal sorting receptor (CIMPR) from the endosome |
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| Disease |
| H00048 | Hepatocellular carcinoma |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09120 Genetic Information Processing
09125 Information processing in viruses
03266 Virion - Herpesvirus
3482 (IGF2R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
3482 (IGF2R)
04142 Lysosome biogenesis
3482 (IGF2R)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:hsa04147]
3482 (IGF2R)
04090 CD molecules [BR:hsa04090]
3482 (IGF2R)
04091 Lectins [BR:hsa04091]
3482 (IGF2R)
Exosome [BR:hsa04147]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
3482 (IGF2R)
CD molecules [BR:hsa04090]
Proteins
3482 (IGF2R)
Lectins [BR:hsa04091]
P-type lectins
3482 (IGF2R)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| LinkDB |
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| Position |
6:159969082..160111504
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| AA seq |
2491 aa
MGAAAGRSPHLGPAPARRPQRSLLLLQLLLLVAAPGSTQAQAAPFPELCSYTWEAVDTKN
NVLYKINICGSVDIVQCGPSSAVCMHDLKTRTYHSVGDSVLRSATRSLLEFNTTVSCDQQ
GTNHRVQSSIAFLCGKTLGTPEFVTATECVHYFEWRTTAACKKDIFKANKEVPCYVFDEE
LRKHDLNPLIKLSGAYLVDDSDPDTSLFINVCRDIDTLRDPGSQLRACPPGTAACLVRGH
QAFDVGQPRDGLKLVRKDRLVLSYVREEAGKLDFCDGHSPAVTITFVCPSERREGTIPKL
TAKSNCRYEIEWITEYACHRDYLESKTCSLSGEQQDVSIDLTPLAQSGGSSYISDGKEYL
FYLNVCGETEIQFCNKKQAAVCQVKKSDTSQVKAAGRYHNQTLRYSDGDLTLIYFGGDEC
SSGFQRMSVINFECNKTAGNDGKGTPVFTGEVDCTYFFTWDTEYACVKEKEDLLCGATDG
KKRYDLSALVRHAEPEQNWEAVDGSQTETEKKHFFINICHRVLQEGKARGCPEDAAVCAV
DKNGSKNLGKFISSPMKEKGNIQLSYSDGDDCGHGKKIKTNITLVCKPGDLESAPVLRTS
GEGGCFYEFEWHTAAACVLSKTEGENCTVFDSQAGFSFDLSPLTKKNGAYKVETKKYDFY
INVCGPVSVSPCQPDSGACQVAKSDEKTWNLGLSNAKLSYYDGMIQLNYRGGTPYNNERH
TPRATLITFLCDRDAGVGFPEYQEEDNSTYNFRWYTSYACPEEPLECVVTDPSTLEQYDL
SSLAKSEGGLGGNWYAMDNSGEHVTWRKYYINVCRPLNPVPGCNRYASACQMKYEKDQGS
FTEVVSISNLGMAKTGPVVEDSGSLLLEYVNGSACTTSDGRQTTYTTRIHLVCSRGRLNS
HPIFSLNWECVVSFLWNTEAACPIQTTTDTDQACSIRDPNSGFVFNLNPLNSSQGYNVSG
IGKIFMFNVCGTMPVCGTILGKPASGCEAETQTEELKNWKPARPVGIEKSLQLSTEGFIT
LTYKGPLSAKGTADAFIVRFVCNDDVYSGPLKFLHQDIDSGQGIRNTYFEFETALACVPS
PVDCQVTDLAGNEYDLTGLSTVRKPWTAVDTSVDGRKRTFYLSVCNPLPYIPGCQGSAVG
SCLVSEGNSWNLGVVQMSPQAAANGSLSIMYVNGDKCGNQRFSTRITFECAQISGSPAFQ
LQDGCEYVFIWRTVEACPVVRVEGDNCEVKDPRHGNLYDLKPLGLNDTIVSAGEYTYYFR
VCGKLSSDVCPTSDKSKVVSSCQEKREPQGFHKVAGLLTQKLTYENGLLKMNFTGGDTCH
KVYQRSTAIFFYCDRGTQRPVFLKETSDCSYLFEWRTQYACPPFDLTECSFKDGAGNSFD
LSSLSRYSDNWEAITGTGDPEHYLINVCKSLAPQAGTEPCPPEAAACLLGGSKPVNLGRV
RDGPQWRDGIIVLKYVDGDLCPDGIRKKSTTIRFTCSESQVNSRPMFISAVEDCEYTFAW
PTATACPMKSNEHDDCQVTNPSTGHLFDLSSLSGRAGFTAAYSEKGLVYMSICGENENCP
PGVGACFGQTRISVGKANKRLRYVDQVLQLVYKDGSPCPSKSGLSYKSVISFVCRPEARP
TNRPMLISLDKQTCTLFFSWHTPLACEQATECSVRNGSSIVDLSPLIHRTGGYEAYDESE
DDASDTNPDFYINICQPLNPMHGVPCPAGAAVCKVPIDGPPIDIGRVAGPPILNPIANEI
YLNFESSTPCLADKHFNYTSLIAFHCKRGVSMGTPKLLRTSECDFVFEWETPVVCPDEVR
MDGCTLTDEQLLYSFNLSSLSTSTFKVTRDSRTYSVGVCTFAVGPEQGGCKDGGVCLLSG
TKGASFGRLQSMKLDYRHQDEAVVLSYVNGDRCPPETDDGVPCVFPFIFNGKSYEECIIE
SRAKLWCSTTADYDRDHEWGFCRHSNSYRTSSIIFKCDEDEDIGRPQVFSEVRGCDVTFE
WKTKVVCPPKKLECKFVQKHKTYDLRLLSSLTGSWSLVHNGVSYYINLCQKIYKGPLGCS
ERASICRRTTTGDVQVLGLVHTQKLGVIGDKVVVTYSKGYPCGGNKTASSVIELTCTKTV
GRPAFKRFDIDSCTYYFSWDSRAACAVKPQEVQMVNGTITNPINGKSFSLGDIYFKLFRA
SGDMRTNGDNYLYEIQLSSITSSRNPACSGANICQVKPNDQHFSRKVGTSDKTKYYLQDG
DLDVVFASSSKCGKDKTKSVSSTIFFHCDPLVEDGIPEFSHETADCQYLFSWYTSAVCPL
GVGFDSENPGDDGQMHKGLSERSQAVGAVLSLLLVALTCCLLALLLYKKERRETVISKLT
TCCRRSSNVSYKYSKVNKEEETDENETEWLMEEIQLPPPRQGKEGQENGHITTKSVKALS
SLHGDDQDSEDEVLTIPEVKVHSGRGAGAESSHPVRNAQSNALQEREDDRVGLVRGEKAR
KGKSSSAQQKTVSSTKLVSFHDDSDEDLLHI |
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| NT seq |
7476 nt +upstreamnt +downstreamnt
atgggggccgccgccggccggagcccccacctggggcccgcgcccgcccgccgcccgcag
cgctctctgctcctgctgcagctgctgctgctcgtcgctgccccggggtccacgcaggcc
caggccgccccgttccccgagctgtgcagttatacatgggaagctgttgataccaaaaat
aatgtactttataaaatcaacatctgtggaagtgtggatattgtccagtgcgggccatca
agtgctgtttgtatgcacgacttgaagacacgcacttatcattcagtgggtgactctgtt
ttgagaagtgcaaccagatctctcctggaattcaacacaacagtgagctgtgaccagcaa
ggcacaaatcacagagtccagagcagcattgccttcctgtgtgggaaaaccctgggaact
cctgaatttgtaactgcaacagaatgtgtgcactactttgagtggaggaccactgcagcc
tgcaagaaagacatatttaaagcaaataaggaggtgccatgctatgtgtttgatgaagag
ttgaggaagcatgatctcaatcctctgatcaagcttagtggtgcctacttggtggatgac
tccgatccggacacttctctattcatcaatgtttgtagagacatagacacactacgagac
ccaggttcacagctgcgggcctgtccccccggcactgccgcctgcctggtaagaggacac
caggcgtttgatgttggccagccccgggacggactgaagctggtgcgcaaggacaggctt
gtcctgagttacgtgagggaagaggcaggaaagctagacttttgtgatggtcacagccct
gcggtgactattacatttgtttgcccgtcggagcggagagagggcaccattcccaaactc
acagctaaatccaactgccgctatgaaattgagtggattactgagtatgcctgccacaga
gattacctggaaagtaaaacttgttctctgagcggcgagcagcaggatgtctccatagac
ctcacaccacttgcccagagcggaggttcatcctatatttcagatggaaaagaatatttg
ttttatttgaatgtctgtggagaaactgaaatacagttctgtaataaaaaacaagctgca
gtttgccaagtgaaaaagagcgatacctctcaagtcaaagcagcaggaagataccacaat
cagaccctccgatattcggatggagacctcaccttgatatattttggaggtgatgaatgc
agctcagggtttcagcggatgagcgtcataaactttgagtgcaataaaaccgcaggtaac
gatgggaaaggaactcctgtattcacaggggaggttgactgcacctacttcttcacatgg
gacacggaatacgcctgtgttaaggagaaggaagacctcctctgcggtgccaccgacggg
aagaagcgctatgacctgtccgcgctggtccgccatgcagaaccagagcagaattgggaa
gctgtggatggcagtcagacggaaacagagaagaagcattttttcattaatatttgtcac
agagtgctgcaggaaggcaaggcacgagggtgtcccgaggacgcggcagtgtgtgcagtg
gataaaaatggaagtaaaaatctgggaaaatttatttcctctcccatgaaagagaaagga
aacattcaactctcttattcagatggtgatgattgtggtcatggcaagaaaattaaaact
aatatcacacttgtatgcaagccaggtgatctggaaagtgcaccagtgttgagaacttct
ggggaaggcggttgcttttatgagtttgagtggcacacagctgcggcctgtgtgctgtct
aagacagaaggggagaactgcacggtctttgactcccaggcagggttttcttttgactta
tcacctctcacaaagaaaaatggtgcctataaagttgagacaaagaagtatgacttttat
ataaatgtgtgtggcccggtgtctgtgagcccctgtcagccagactcaggagcctgccag
gtggcaaaaagtgatgagaagacttggaacttgggtctgagtaatgcgaagctttcatat
tatgatgggatgatccaactgaactacagaggcggcacaccctataacaatgaaagacac
acaccgagagctacgctcatcacctttctctgtgatcgagacgcgggagtgggcttccct
gaatatcaggaagaggataactccacctacaacttccggtggtacaccagctatgcctgc
ccggaggagcccctggaatgcgtagtgaccgacccctccacgctggagcagtacgacctc
tccagtctggcaaaatctgaaggtggccttggaggaaactggtatgccatggacaactca
ggggaacatgtcacgtggaggaaatactacattaacgtgtgtcggcctctgaatccagtg
ccgggctgcaaccgatatgcatcggcttgccagatgaagtatgaaaaagatcagggctcc
ttcactgaagtggtttccatcagtaacttgggaatggcaaagaccggcccggtggttgag
gacagcggcagcctccttctggaatacgtgaatgggtcggcctgcaccaccagcgatggc
agacagaccacatataccacgaggatccatctcgtctgctccaggggcaggctgaacagc
caccccatcttttctctcaactgggagtgtgtggtcagtttcctgtggaacacagaggct
gcctgtcccattcagacaacgacggatacagaccaggcttgctctataagggatcccaac
agtggatttgtgtttaatcttaatccgctaaacagttcgcaaggatataacgtctctggc
attgggaagatttttatgtttaatgtctgcggcacaatgcctgtctgtgggaccatcctg
ggaaaacctgcttctggctgtgaggcagaaacccaaactgaagagctcaagaattggaag
ccagcaaggccagtcggaattgagaaaagcctccagctgtccacagagggcttcatcact
ctgacctacaaagggcctctctctgccaaaggtaccgctgatgcttttatcgtccgcttt
gtttgcaatgatgatgtttactcagggcccctcaaattcctgcatcaagatatcgactct
gggcaagggatccgaaacacttactttgagtttgaaaccgcgttggcctgtgttccttct
ccagtggactgccaagtcaccgacctggctggaaatgagtacgacctgactggcctaagc
acagtcaggaaaccttggacggctgttgacacctctgtcgatgggagaaagaggactttc
tatttgagcgtttgcaatcctctcccttacattcctggatgccagggcagcgcagtgggg
tcttgcttagtgtcagaaggcaatagctggaatctgggtgtggtgcagatgagtccccaa
gccgcggcgaatggatctttgagcatcatgtatgtcaacggtgacaagtgtgggaaccag
cgcttctccaccaggatcacgtttgagtgtgctcagatatcgggctcaccagcatttcag
cttcaggatggttgtgagtacgtgtttatctggagaactgtggaagcctgtcccgttgtc
agagtggaaggggacaactgtgaggtgaaagacccaaggcatggcaacttgtatgacctg
aagcccctgggcctcaacgacaccatcgtgagcgctggcgaatacacttattacttccgg
gtctgtgggaagctttcctcagacgtctgccccacaagtgacaagtccaaggtggtctcc
tcatgtcaggaaaagcgggaaccgcagggatttcacaaagtggcaggtctcctgactcag
aagctaacttatgaaaatggcttgttaaaaatgaacttcacggggggggacacttgccat
aaggtttatcagcgctccacagccatcttcttctactgtgaccgcggcacccagcggcca
gtatttctaaaggagacttcagattgttcctacttgtttgagtggcgaacgcagtatgcc
tgcccacctttcgatctgactgaatgttcattcaaagatggggctggcaactccttcgac
ctctcgtccctgtcaaggtacagtgacaactgggaagccatcactgggacgggggacccg
gagcactacctcatcaatgtctgcaagtctctggccccgcaggctggcactgagccgtgc
cctccagaagcagccgcgtgtctgctgggtggctccaagcccgtgaacctcggcagggta
agggacggacctcagtggagagatggcataattgtcctgaaatacgttgatggcgactta
tgtccagatgggattcggaaaaagtcaaccaccatccgattcacctgcagcgagagccaa
gtgaactccaggcccatgttcatcagcgccgtggaggactgtgagtacacctttgcctgg
cccacagccacagcctgtcccatgaagagcaacgagcatgatgactgccaggtcaccaac
ccaagcacaggacacctgtttgatctgagctccttaagtggcagggcgggattcacagct
gcttacagcgagaaggggttggtttacatgagcatctgtggggagaatgaaaactgccct
cctggcgtgggggcctgctttggacagaccaggattagcgtgggcaaggccaacaagagg
ctgagatacgtggaccaggtcctgcagctggtgtacaaggatgggtccccttgtccctcc
aaatccggcctgagctataagagtgtgatcagtttcgtgtgcaggcctgaggccaggcca
accaataggcccatgctcatctccctggacaagcagacatgcactctcttcttctcctgg
cacacgccgctggcctgcgagcaagcgaccgaatgttccgtgaggaatggaagctctatt
gttgacttgtctccccttattcatcgcactggtggttatgaggcttatgatgagagtgag
gatgatgcctccgataccaaccctgatttctacatcaatatttgtcagccactaaatccc
atgcacggagtgccctgtcctgccggagccgctgtgtgcaaagttcctattgatggtccc
cccatagatatcggccgggtagcaggaccaccaatactcaatccaatagcaaatgagatt
tacttgaattttgaaagcagtactccttgcttagcggacaagcatttcaactacacctcg
ctcatcgcgtttcactgtaagagaggtgtgagcatgggaacgcctaagctgttaaggacc
agcgagtgcgactttgtgttcgaatgggagactcctgtcgtctgtcctgatgaagtgagg
atggatggctgtaccctgacagatgagcagctcctctacagcttcaacttgtccagcctt
tccacgagcacctttaaggtgactcgcgactcgcgcacctacagcgttggggtgtgcacc
tttgcagtcgggccagaacaaggaggctgtaaggacggaggagtctgtctgctctcaggc
accaagggggcatcctttggacggctgcaatcaatgaaactggattacaggcaccaggat
gaagcggtcgttttaagttacgtgaatggtgatcgttgccctccagaaaccgatgacggc
gtcccctgtgtcttccccttcatattcaatgggaagagctacgaggagtgcatcatagag
agcagggcgaagctgtggtgtagcacaactgcggactacgacagagaccacgagtggggc
ttctgcagacactcaaacagctaccggacatccagcatcatatttaagtgtgatgaagat
gaggacattgggaggccacaagtcttcagtgaagtgcgtgggtgtgatgtgacatttgag
tggaaaacaaaagttgtctgccctccaaagaagttggagtgcaaattcgtccagaaacac
aaaacctacgacctgcggctgctctcctctctcaccgggtcctggtccctcgtccacaac
ggagtctcgtactatataaatctgtgccagaaaatatataaagggcccctgggctgctct
gaaagggccagcatttgcagaaggaccacaactggtgacgtccaggtcctgggactcgtt
cacacgcagaagctgggtgtcataggtgacaaagttgttgtcacgtactccaaaggttat
ccgtgtggtggaaataagaccgcatcctccgtgatagaattgacctgtacaaagacggtg
ggcagacctgcattcaagaggtttgatatcgacagctgcacttactacttcagctgggac
tcccgggctgcctgcgccgtgaagcctcaggaggtgcagatggtgaatgggaccatcacc
aaccctataaatggcaagagcttcagcctcggagatatttattttaagctgttcagagcc
tctggggacatgaggaccaatggggacaactacctgtatgagatccaactttcctccatc
acaagctccagaaacccggcgtgctctggagccaacatatgccaggtgaagcccaacgat
cagcacttcagtcggaaagttggaacctctgacaagaccaagtactaccttcaagacggc
gatctcgatgtcgtgtttgcctcttcctctaagtgcggaaaggataagaccaagtctgtt
tcttccaccatcttcttccactgtgaccctctggtggaggacgggatccccgagttcagt
cacgagactgccgactgccagtacctcttctcttggtacacctcagccgtgtgtcctctg
ggggtgggctttgacagcgagaatcccggggacgacgggcagatgcacaaggggctgtca
gaacggagccaggcagtcggcgcggtgctcagcctgctgctggtggcgctcacctgctgc
ctgctggccctgttgctctacaagaaggagaggagggaaacagtgataagtaagctgacc
acttgctgtaggagaagttccaacgtgtcctacaaatactcaaaggtgaataaggaagaa
gagacagatgagaatgaaacagagtggctgatggaagagatccagctgcctcctccacgg
cagggaaaggaagggcaggagaacggccatattaccaccaagtcagtgaaagccctcagc
tccctgcatggggatgaccaggacagtgaggatgaggttctgaccatcccagaggtgaaa
gttcactcgggcaggggagctggggcagagagctcccacccagtgagaaacgcacagagc
aatgcccttcaggagcgtgaggacgatagggtggggctggtcaggggtgagaaggcgagg
aaagggaagtccagctctgcacagcagaagacagtgagctccaccaagctggtgtccttc
catgacgacagcgacgaggacctcttacacatctga |
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