Homo sapiens (human): 4121
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Entry
4121 CDS
T01001
Symbol
MAN1A1, HUMM3, HUMM9, MAN9
Name
(RefSeq) mannosidase alpha class 1A member 1
KO
K01230
mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:
3.2.1.113
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00510
N-Glycan biosynthesis
hsa00513
Various types of N-glycan biosynthesis
hsa01100
Metabolic pathways
hsa04141
Protein processing in endoplasmic reticulum
Module
hsa_M00073
N-glycan precursor trimming
Network
nt06015
N-Glycan biosynthesis
Element
N00820
N-Glycan biosynthesis
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00510 N-Glycan biosynthesis
4121 (MAN1A1)
00513 Various types of N-glycan biosynthesis
4121 (MAN1A1)
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
4121 (MAN1A1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
4121 (MAN1A1)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.2 Glycosylases
3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
3.2.1.113 mannosyl-oligosaccharide 1,2-alpha-mannosidase
4121 (MAN1A1)
Membrane trafficking [BR:
hsa04131
]
Endoplasmic reticulum (ER) - Golgi transport
Forward pathways
ER-Golgi intermediate compartment (ERGIC) proteins
4121 (MAN1A1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Glyco_hydro_47
AIM5
DnaB_bind
Motif
Other DBs
NCBI-GeneID:
4121
NCBI-ProteinID:
NP_005898
OMIM:
604344
HGNC:
6821
Ensembl:
ENSG00000111885
UniProt:
P33908
LinkDB
All DBs
Position
6:complement(119177205..119350605)
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AA seq
653 aa
AA seq
DB search
MPVGGLLPLFSSPAGGVLGGGLGGGGGRKGSGPAALRLTEKFVLLLVFSAFITLCFGAIF
FLPDSSKLLSGVLFHSSPALQPAADHKPGPGARAEDAAEGRARRREEGAPGDPEAALEDN
LARIRENHERALREAKETLQKLPEEIQRDILLEKKKVAQDQLRDKAPFRGLPPVDFVPPI
GVESREPADAAIREKRAKIKEMMKHAWNNYKGYAWGLNELKPISKGGHSSSLFGNIKGAT
IVDALDTLFIMEMKHEFEEAKSWVEENLDFNVNAEISVFEVNIRFVGGLLSAYYLSGEEI
FRKKAVELGVKLLPAFHTPSGIPWALLNMKSGIGRNWPWASGGSSILAEFGTLHLEFMHL
SHLSGNPIFAEKVMNIRTVLNKLEKPQGLYPNYLNPSSGQWGQHHVSVGGLGDSFYEYLL
KAWLMSDKTDLEAKKMYFDAVQAIETHLIRKSSSGLTYIAEWKGGLLEHKMGHLTCFAGG
MFALGADAAPEGMAQHYLELGAEIARTCHESYNRTFMKLGPEAFRFDGGVEAIATRQNEK
YYILRPEVMETYMYMWRLTHDPKYRKWAWEAVEALENHCRVNGGYSGLRDVYLLHESYDD
VQQSFFLAETLKYLYLIFSDDDLLPLEHWIFNSEAHLLPILPKDKKEVEIREE
NT seq
1962 nt
NT seq
+upstream
nt +downstream
nt
atgcccgtggggggcctgttgccgctcttcagcagccccgcgggcggcgtcctgggcggg
gggctcggcggcggcggtggcaggaaggggtcgggccccgccgccctccgcctgacggag
aagttcgtgctgctgctggtattcagcgccttcatcacgctctgcttcggggcgatcttc
ttcctgccagactcctccaagctgctcagcggggtcctgttccactccagccccgccttg
cagccggccgccgaccacaagcccgggcccggggcgcgcgccgaggacgcggccgagggg
cgagcccggcgccgcgaggagggggcacccggggacccggaggccgccctggaggacaac
ttggccaggatccgcgaaaaccacgagcgggctctcagggaagccaaggagaccctgcag
aagctgcccgaggagatccaaagagacatcctactggagaagaagaaggtggcccaggac
cagctgcgtgacaaggcgccgttcagaggcctgcccccggtggacttcgtgcccccaatc
ggggtggagagccgggagcccgccgacgccgccatccgcgagaaaagggcaaagatcaaa
gagatgatgaaacatgcttggaataattataaaggttatgcctggggattaaatgaactc
aaacctatatcaaaaggaggccattcaagcagtttgtttggtaacatcaaaggagcaact
atagtagatgccctggatacactttttattatggaaatgaaacatgaatttgaagaagca
aaatcatgggttgaagaaaatttagattttaatgtgaatgctgaaatttctgtctttgaa
gtaaatatacgctttgttggtggactactctcagcctactatctgtctggagaagagatt
tttcgaaagaaagcagtggaacttggggtaaaattgctacctgcatttcatactccctct
ggaataccttgggcattgctgaatatgaaaagtggtattggaaggaactggccctgggcc
tctggaggcagcagtattctggcagaatttggaaccctgcatttggagtttatgcacttg
agccacttatcaggaaaccccatctttgctgaaaaggtaatgaatattcgaacagtactg
aacaaactggaaaaaccacaaggcctttatcctaactatctgaatcccagtagtggacag
tggggtcaacatcatgtatcagttggaggacttggagacagcttctatgagtatttgctg
aaggcctggttaatgtctgacaagacagatctggaagctaagaagatgtattttgatgct
gttcaggctatcgagactcatttgatccgcaagtctagcagcggactaacttatatcgca
gagtggaaagggggcctcctggagcacaagatgggccacctgacctgcttcgcggggggc
atgttcgcactcggggctgatgcagctcccgaaggcatggcccaacactaccttgaactc
ggggctgaaattgcccgtacttgtcatgaatcatataatcgaacatttatgaaactggga
ccagaagctttcagatttgatggtggtgttgaagccatcgctacaagacaaaatgaaaaa
tactacatcttacggccagaagttatggagacttacatgtatatgtggagactgactcat
gatccaaagtacaggaaatgggcctgggaagccgtagaggccttggaaaaccattgcaga
gtgaatggaggctattcaggcctaagggatgtttaccttcttcatgagagttatgatgat
gtgcagcagagtttcttcctggcagagacattgaaatatttgtacctaatattttctgac
gacgatcttcttccactggagcattggatcttcaatagcgaggcacatcttctccctatc
ctccctaaagataaaaaggaagttgaaatcagagaggaataa
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