Homo sapiens (human): 4200
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Entry
4200 CDS
T01001
Symbol
ME2, ODS1
Name
(RefSeq) malic enzyme 2
KO
K00027
malate dehydrogenase (oxaloacetate-decarboxylating) [EC:
1.1.1.38
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00620
Pyruvate metabolism
hsa01200
Carbon metabolism
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
4200 (ME2)
Enzymes [BR:
hsa01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.38 malate dehydrogenase (oxaloacetate-decarboxylating)
4200 (ME2)
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Gene cluster
GFIT
Motif
Pfam:
Malic_M
malic
Motif
Other DBs
NCBI-GeneID:
4200
NCBI-ProteinID:
NP_002387
OMIM:
154270
HGNC:
6984
Ensembl:
ENSG00000082212
UniProt:
P23368
Structure
PDB
PDBj
LinkDB
All DBs
Position
18:50879118..50954257
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AA seq
584 aa
AA seq
DB search
MLSRLRVVSTTCTLACRHLHIKEKGKPLMLNPRTNKGMAFTLQERQMLGLQGLLPPKIET
QDIQALRFHRNLKKMTSPLEKYIYIMGIQERNEKLFYRILQDDIESLMPIVYTPTVGLAC
SQYGHIFRRPKGLFISISDRGHVRSIVDNWPENHVKAVVVTDGERILGLGDLGVYGMGIP
VGKLCLYTACAGIRPDRCLPVCIDVGTDNIALLKDPFYMGLYQKRDRTQQYDDLIDEFMK
AITDRYGRNTLIQFEDFGNHNAFRFLRKYREKYCTFNDDIQGTAAVALAGLLAAQKVISK
PISEHKILFLGAGEAALGIANLIVMSMVENGLSEQEAQKKIWMFDKYGLLVKGRKAKIDS
YQEPFTHSAPESIPDTFEDAVNILKPSTIIGVAGAGRLFTPDVIRAMASINERPVIFALS
NPTAQAECTAEEAYTLTEGRCLFASGSPFGPVKLTDGRVFTPGQGNNVYIFPGVALAVIL
CNTRHISDSVFLEAAKALTSQLTDEELAQGRLYPPLANIQEVSINIAIKVTEYLYANKMA
FRYPEPEDKAKYVKERTWRSEYDSLLPDVYEWPESASSPPVITE
NT seq
1755 nt
NT seq
+upstream
nt +downstream
nt
atgttgtcccggttaagagtagtttccaccacttgtactttggcatgtcgacatttgcac
ataaaagaaaaaggcaagccacttatgctgaacccaagaacaaacaagggaatggcattt
actttacaagaacgacaaatgcttggtcttcaaggacttctacctcccaaaatagagaca
caagatattcaagccttacgatttcatagaaacttgaagaaaatgactagccctttggaa
aaatatatctacataatgggaatacaagaaagaaatgagaaattgttttatagaatactg
caagatgacattgagagtttaatgccaattgtatatacaccgacggttggtcttgcctgc
tcccagtatggacacatctttagaagacctaagggattatttatttcgatctcagacaga
ggtcatgttagatcaattgtggataactggccagaaaatcatgttaaggctgttgtagtg
actgatggagagagaattctgggtcttggagatctgggtgtctatggaatgggaattcca
gtaggaaaactttgtttgtatacagcttgtgcaggaatacggcctgatagatgcctgcca
gtgtgtattgatgtgggaactgataatatcgcactcttaaaagacccattttacatgggc
ttgtaccagaaacgagatcgcacacaacagtatgatgacctgattgatgagtttatgaaa
gctattactgacagatatggccggaacacactcattcagttcgaagactttggaaatcat
aatgcattcaggttcttgagaaagtaccgagaaaaatattgtactttcaatgatgatatt
caagggacagctgcagtagctctagcaggtcttcttgcagcacaaaaagttattagtaaa
ccaatctccgaacacaaaatcttattccttggagcaggagaggctgctcttggaattgca
aatcttatagttatgtctatggtagaaaatggcctgtcagaacaagaggcacaaaagaaa
atctggatgtttgacaagtatggtttattagttaagggacggaaagcaaaaatagatagt
tatcaggaaccatttactcactcagccccagagagcatacctgatacttttgaagatgca
gtgaatatactgaagccttcaactataattggagttgcaggtgctggccgtcttttcact
cctgatgtaatcagagccatggcctctatcaatgaaaggcctgtaatatttgcattaagt
aatcctacagcacaggcagagtgcacggctgaagaagcatatacacttacagagggcagg
tgtttgtttgccagtggcagtccatttgggccagtgaaacttacagatgggcgagtcttt
acaccaggtcaaggaaacaatgtttatatttttccaggtgtggctttagctgttattctc
tgtaacacccggcatattagtgacagtgttttcctagaagctgcaaaggccctgacaagc
caattgacagatgaagagctagcccaagggagactttacccaccgcttgctaatattcag
gaagtttctattaacattgctattaaagttacagaatacctatatgctaataaaatggct
ttccgatacccagaacctgaagacaaggccaaatatgttaaagaaagaacatggcggagt
gaatatgattccctgctgccagatgtgtatgaatggccagaatctgcatcaagccctcct
gtgataacagaatag
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