Homo sapiens (human): 4218
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Entry
4218 CDS
T01001
Symbol
RAB8A, MEL, RAB8
Name
(RefSeq) RAB8A, member RAS oncogene family
KO
K07901
Ras-related protein Rab-8A
Organism
hsa
Homo sapiens (human)
Pathway
hsa04140
Autophagy - animal
hsa04144
Endocytosis
hsa04152
AMPK signaling pathway
hsa04530
Tight junction
hsa04972
Pancreatic secretion
hsa05014
Amyotrophic lateral sclerosis
hsa05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
4218 (RAB8A)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
4218 (RAB8A)
04140 Autophagy - animal
4218 (RAB8A)
09144 Cellular community - eukaryotes
04530 Tight junction
4218 (RAB8A)
09150 Organismal Systems
09154 Digestive system
04972 Pancreatic secretion
4218 (RAB8A)
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
4218 (RAB8A)
05022 Pathways of neurodegeneration - multiple diseases
4218 (RAB8A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
4218 (RAB8A)
03036 Chromosome and associated proteins [BR:
hsa03036
]
4218 (RAB8A)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hsa04147
]
4218 (RAB8A)
04031 GTP-binding proteins [BR:
hsa04031
]
4218 (RAB8A)
Membrane trafficking [BR:
hsa04131
]
Exocytosis
Small GTPases and associated proteins
Rab GTPases
4218 (RAB8A)
Autophagy
Other autophagy associated proteins
4218 (RAB8A)
Chromosome and associated proteins [BR:
hsa03036
]
Eukaryotic type
Centrosome formation proteins
Other centriole associated proteins
4218 (RAB8A)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
4218 (RAB8A)
Exosomal proteins of other body fluids (saliva and urine)
4218 (RAB8A)
Exosomal proteins of colorectal cancer cells
4218 (RAB8A)
GTP-binding proteins [BR:
hsa04031
]
Small (monomeric) G-proteins
Rab Family
Rab8/10/13 [OT]
4218 (RAB8A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ras
Roc
Arf
Gtr1_RagA
GTP_EFTU
SRPRB
MMR_HSR1
DUF3963
Septin
AAA_7
Phage_holin_6_1
Motif
Other DBs
NCBI-GeneID:
4218
NCBI-ProteinID:
NP_005361
OMIM:
165040
HGNC:
7007
Ensembl:
ENSG00000167461
UniProt:
P61006
Structure
PDB
LinkDB
All DBs
Position
19:16111889..16134234
Genome browser
AA seq
207 aa
AA seq
DB search
MAKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQ
IWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILG
NKCDVNDKRQVSKERGEKLALDYGIKFMETSAKANINVENAFFTLARDIKAKMDKKLEGN
SPQGSNQGVKITPDQQKRSSFFRCVLL
NT seq
624 nt
NT seq
+upstream
nt +downstream
nt
atggcgaagacctacgattacctgttcaagctgctgctgatcggggactcgggggtgggg
aagacctgtgtcctgttccgcttctccgaggacgccttcaactccacttttatctccacc
ataggaattgactttaaaattaggaccatagagctcgatggcaagagaattaaactgcag
atatgggacacagccggtcaggaacggtttcggacgatcacaacggcctactacaggggt
gcaatgggcatcatgctggtctacgacatcaccaacgagaagtccttcgacaacatccgg
aactggattcgcaacattgaggagcacgcctctgcagacgtcgaaaagatgatactcggg
aacaagtgtgatgtgaatgacaagagacaagtttccaaggaacggggagaaaagctggcc
ctcgactatggaatcaagttcatggagaccagcgcgaaggccaacatcaatgtggaaaat
gcatttttcactctcgccagagatatcaaagcaaaaatggacaaaaaattggaaggcaac
agcccccaggggagcaaccagggagtcaaaatcacaccggaccagcagaagaggagcagc
tttttccgatgtgttcttctgtga
DBGET
integrated database retrieval system