Homo sapiens (human): 4293
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Entry
4293 CDS
T01001
Symbol
MAP3K9, MEKK9, MLK1, PRKE1
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 9
KO
K04417
mitogen-activated protein kinase kinase kinase 9 [EC:
2.7.11.25
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04010
MAPK signaling pathway
Network
nt06526
MAPK signaling
Element
N01594
MLK-JNK signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
4293 (MAP3K9)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
4293 (MAP3K9)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: TKL group
MLK family
4293 (MAP3K9)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
SH3_9
SH3_2
SH3_1
ABC1
Pkinase_fungal
OmpH
Motif
Other DBs
NCBI-GeneID:
4293
NCBI-ProteinID:
NP_001271159
OMIM:
600136
HGNC:
6861
Ensembl:
ENSG00000006432
UniProt:
P80192
Q8NEB1
Structure
PDB
PDBj
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All DBs
Position
14:complement(70722526..70809513)
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AA seq
1104 aa
AA seq
DB search
MEPSRALLGCLASAAAAAPPGEDGAGAGAEEEEEEEEEAAAAVGPGELGCDAPLPYWTAV
FEYEAAGEDELTLRLGDVVEVLSKDSQVSGDEGWWTGQLNQRVGIFPSNYVTPRSAFSSR
CQPGGEDPSCYPPIQLLEIDFAELTLEEIIGIGGFGKVYRAFWIGDEVAVKAARHDPDED
ISQTIENVRQEAKLFAMLKHPNIIALRGVCLKEPNLCLVMEFARGGPLNRVLSGKRIPPD
ILVNWAVQIARGMNYLHDEAIVPIIHRDLKSSNILILQKVENGDLSNKILKITDFGLARE
WHRTTKMSAAGTYAWMAPEVIRASMFSKGSDVWSYGVLLWELLTGEVPFRGIDGLAVAYG
VAMNKLALPIPSTCPEPFAKLMEDCWNPDPHSRPSFTNILDQLTTIEESGFFEMPKDSFH
CLQDNWKHEIQEMFDQLRAKEKELRTWEEELTRAALQQKNQEELLRRREQELAEREIDIL
ERELNIIIHQLCQEKPRVKKRKGKFRKSRLKLKDGNRISLPSDFQHKFTVQASPTMDKRK
SLINSRSSPPASPTIIPRLRAIQLTPGESSKTWGRSSVVPKEEGEEEEKRAPKKKGRTWG
PGTLGQKELASGDEGSPQRREKANGLSTPSESPHFHLGLKSLVDGYKQWSSSAPNLVKGP
RSSPALPGFTSLMEMEDEDSEGPGSGESRLQHSPSQSYLCIPFPRGEDGDGPSSDGIHEE
PTPVNSATSTPQLTPTNSLKRGGAHHRRCEVALLGCGAVLAATGLGFDLLEAGKCQLLPL
EEPEPPAREEKKRREGLFQRSSRPRRSTSPPSRKLFKKEEPMLLLGDPSASLTLLSLSSI
SECNSTRSLLRSDSDEIVVYEMPVSPVEAPPLSPCTHNPLVNVRVERFKRDPNQSLTPTH
VTLTTPSQPSSHRRTPSDGALKPETLLASRSPSSNGLSPSPGAGMLKTPSPSRDPGEFPR
LPDPNVVFPPTPRRWNTQQDSTLERPKTLEFLPRPRPSANRQRLDPWWFVSPSHARSTSP
ANSSSTETPSNLDSCFASSSSTVEERPGLPALLPFQAGPLPPTERTLLDLDAEGQSQDST
VPLCRAELNTHRPAPYEIQQEFWS
NT seq
3315 nt
NT seq
+upstream
nt +downstream
nt
atggagccctccagagcgcttctcggctgcctagcgagcgccgccgctgccgccccgccg
ggggaggatggagcaggggccggggccgaggaggaggaggaggaggaggaggaggcggcg
gcggcggtgggccccggggagctgggctgcgacgcgccgctgccctactggacggccgtg
ttcgagtacgaggcggcgggcgaggacgagctgaccctgcggctgggcgacgtggtggag
gtgctgtccaaggactcgcaggtgtccggcgacgagggctggtggaccgggcagctgaac
cagcgggtgggcatcttccccagcaactacgtgaccccgcgcagcgccttctccagccgc
tgccagcccggcggcgaggaccccagttgctacccgcccattcagttgttagaaattgat
tttgcggagctcaccttggaagagattattggcatcgggggctttgggaaggtctatcgt
gctttctggataggggatgaggttgctgtgaaagcagctcgccacgaccctgatgaggac
atcagccagaccatagagaatgttcgccaagaggccaagctcttcgccatgctgaagcac
cccaacatcattgccctaagaggggtatgtctgaaggagcccaacctctgcttggtcatg
gagtttgctcgtggaggacctttgaatagagtgttatctgggaaaaggattcccccagac
atcctggtgaattgggctgtgcagattgccagagggatgaactacttacatgatgaggca
attgttcccatcatccaccgcgaccttaagtccagcaacatattgatcctccagaaggtg
gagaatggagacctgagcaacaagattctgaagatcactgattttggcctggctcgggaa
tggcaccgaaccaccaagatgagtgcggcagggacgtatgcttggatggcacccgaagtc
atccgggcctccatgttttccaaaggcagtgatgtgtggagctatggggtgctactttgg
gagttgctgactggtgaggtgccctttcgaggcattgatggcttagcagtcgcttatgga
gtggccatgaacaaactcgcccttcctattccttctacgtgcccagaaccttttgccaaa
ctcatggaagactgctggaatcctgatccccactcacgaccatctttcacgaatatcctg
gaccagctaaccaccatagaggagtctggtttctttgaaatgcccaaggactccttccac
tgcctgcaggacaactggaaacacgagattcaggagatgtttgaccaactcagggccaaa
gaaaaggaacttcgcacctgggaggaggagctgacgcgggctgcactgcagcagaagaac
caggaggaactgctgcggcgtcgggagcaggagctggccgagcgggagattgacatcctg
gaacgggagctcaacatcatcatccaccagctgtgccaggagaagccccgggtgaagaaa
cgcaagggcaagttcaggaagagccggctgaagctcaaggatggcaaccgcatcagcctc
ccttctgatttccagcacaagttcacggtgcaggcctcccctaccatggataaaaggaag
agtcttatcaacagccgctccagtcctcctgcaagccccaccatcattcctcgccttcga
gccatccagttgacaccaggtgaaagcagcaaaacctggggcaggagctcagtcgtccca
aaggaggaaggggaggaggaggagaagagggccccaaagaagaagggacggacgtggggg
ccagggacgcttggtcagaaggagcttgcctcgggagatgaaggatcccctcagagacgt
gagaaagctaatggtttaagtaccccatcagaatctccacatttccacttgggcctcaag
tccctggtagatggatataagcagtggtcgtccagtgcccccaacctggtgaagggccca
aggagtagcccggccctgccagggttcaccagccttatggagatggaggatgaggacagt
gaaggcccagggagtggagagagtcgcctacagcattcacccagccagtcctacctctgt
atcccattccctcgtggagaggatggcgatggcccctccagtgatggaatccatgaggag
cccaccccagtcaactcggccacgagtacccctcagctgacgccaaccaacagcctcaag
cggggcggtgcccaccaccgccgctgcgaggtggctctgctcggctgtggggctgttctg
gcagccacaggcctagggtttgacttgctggaagctggcaagtgccagctgcttcccctg
gaggagcctgagccaccagcccgggaggagaagaaaagacgggagggtctttttcagagg
tccagccgtcctcgtcggagcaccagccccccatcccgaaagcttttcaagaaggaggag
cccatgctgttgctaggagacccctctgcctccctgacgctgctctccctctcctccatc
tccgagtgcaactccacacgctccctgctgcgctccgacagcgatgaaattgtcgtgtat
gagatgccagtcagcccagtcgaggcccctcccctgagtccatgtacccacaaccccctg
gtcaatgtccgagtagagcgcttcaaacgagatcctaaccaatctctgactcccacccat
gtcaccctcaccaccccctcgcagcccagcagtcaccggcggactccttctgatggggcc
cttaagccagagactctcctagccagcaggagcccctccagcaatgggttgagccccagt
cctggagcaggaatgttgaaaacccccagtcccagccgagacccaggtgaattcccccgt
ctccctgaccccaatgtggtcttccccccaaccccaaggcgctggaacactcagcaggac
tctaccttggagagacccaagactctggagtttctgcctcggccgcgtccttctgccaac
cggcaacggctggacccttggtggtttgtgtcccccagccatgcccgcagcacctcccca
gccaacagctccagcacagagacgcccagcaacctggactcctgctttgctagcagtagc
agcactgtagaggagcggcctggacttccagccctgctcccgttccaggcagggccgctg
cccccgactgagcggacgctcctggacctggatgcagaggggcagagtcaggacagcacc
gtgccgctgtgcagagcggaactgaacacacacaggcctgccccttatgagatccagcag
gagttctggtcttag
DBGET
integrated database retrieval system
