Homo sapiens (human): 4317 Help Entry 4317              CDS       T01001                                  Symbol MMP8, CLG1, HNC, MMP-8, PMNL-CL Name (RefSeq) matrix metallopeptidase 8   KO K01402   matrix metalloproteinase-8 (neutrophil collagenase) [EC:3.4.24.34] Organism hsa  Homo sapiens (human) Drug target Cipemastat:  D03517 Rebimastat:  D03800 Brite KEGG Orthology (KO) [BR:hsa00001]  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:hsa01002]     4317 (MMP8) Enzymes [BR:hsa01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.24  Metalloendopeptidases     3.4.24.34  neutrophil collagenase      4317 (MMP8) Peptidases and inhibitors [BR:hsa01002]  Metallo peptidases   Family M10    4317 (MMP8) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_M10 Hemopexin PG_binding_1 Reprolysin_3 Reprolysin_5 Reprolysin_4 DUF4953 Motif Other DBs NCBI-GeneID:  4317 NCBI-ProteinID:  NP_002415 OMIM:  120355 HGNC:  7175 Ensembl:  ENSG00000118113 UniProt:  P22894 Structure PDBPDBj LinkDB All DBs Position 11:complement(102711796..102724954) Genome browser AA seq 467 aa AA seqDB search MFSLKTLPFLLLLHVQISKAFPVSSKEKNTKTVQDYLEKFYQLPSNQYQSTRKNGTNVIV EKLKEMQRFFGLNVTGKPNEETLDMMKKPRCGVPDSGGFMLTPGNPKWERTNLTYRIRNY TPQLSEAEVERAIKDAFELWSVASPLIFTRISQGEADINIAFYQRDHGDNSPFDGPNGIL AHAFQPGQGIGGDAHFDAEETWTNTSANYNLFLVAAHEFGHSLGLAHSSDPGALMYPNYA FRETSNYSLPQDDIDGIQAIYGLSSNPIQPTGPSTPKPCDPSLTFDAITTLRGEILFFKD RYFWRRHPQLQRVEMNFISLFWPSLPTGIQAAYEDFDRDLIFLFKGNQYWALSGYDILQG YPKDISNYGFPSSVQAIDAAVFYRSKTYFFVNDQFWRYDNQRQFMEPGYPKSISGAFPGI ESKVDAVFQQEHFFHVFSGPRYYAFDLIAQRVTRVARGNKWLNCRYG NT seq 1404 nt NT seq  +upstreamnt  +downstreamnt atgttctccctgaagacgcttccatttctgctcttactccatgtgcagatttccaaggcc tttcctgtatcttctaaagagaaaaatacaaaaactgttcaggactacctggaaaagttc taccaattaccaagcaaccagtatcagtctacaaggaagaatggcactaatgtgatcgtt gaaaagcttaaagaaatgcagcgattttttgggttgaatgtgacggggaagccaaatgag gaaactctggacatgatgaaaaagcctcgctgtggagtgcctgacagtggtggttttatg ttaaccccaggaaaccccaagtgggaacgcactaacttgacctacaggattcgaaactat accccacagctgtcagaggctgaggtagaaagagctatcaaggatgcctttgaactctgg agtgttgcatcacctctcatcttcaccaggatctcacagggagaggcagatatcaacatt gctttttaccaaagagatcacggtgacaattctccatttgatggacccaatggaatcctt gctcatgcctttcagccaggccaaggtattggaggagatgctcattttgatgccgaagaa acatggaccaacacctccgcaaattacaacttgtttcttgttgctgctcatgaatttggc cattctttggggctcgctcactcctctgaccctggtgccttgatgtatcccaactatgct ttcagggaaaccagcaactactcactccctcaagatgacatcgatggcattcaggccatc tatggactttcaagcaaccctatccaacctactggaccaagcacacccaaaccctgtgac cccagtttgacatttgatgctatcaccacactccgtggagaaatacttttctttaaagac aggtacttctggagaaggcatcctcagctacaaagagtcgaaatgaattttatttctcta ttctggccatcccttccaactggtatacaggctgcttatgaagattttgacagagacctc attttcctatttaaaggcaaccaatactgggctctgagtggctatgatattctgcaaggt tatcccaaggatatatcaaactatggcttccccagcagcgtccaagcaattgacgcagct gttttctacagaagtaaaacatacttctttgtaaatgaccaattctggagatatgataac caaagacaattcatggagccaggttatcccaaaagcatatcaggtgcctttccaggaata gagagtaaagttgatgcagttttccagcaagaacatttcttccatgtcttcagtggacca agatattacgcatttgatcttattgctcagagagttaccagagttgcaagaggcaataaa tggcttaactgtagatatggctga

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