Homo sapiens (human): 435 Help Entry 435               CDS       T01001                                  Symbol ASL, ASAL Name (RefSeq) argininosuccinate lyase   KO K01755   argininosuccinate lyase [EC:4.3.2.1] Organism hsa  Homo sapiens (human) Pathway hsa00220   Arginine biosynthesis hsa00250   Alanine, aspartate and glutamate metabolism hsa01100   Metabolic pathways hsa01230   Biosynthesis of amino acids Module hsa_M00029   Urea cycle hsa_M00844   Arginine biosynthesis, ornithine => arginine Network nt06010  Urea cycle   Element N00593   Urea cycle Disease H01028   Argininosuccinic aciduria H01398   Primary hyperammonemia (Urea cycle disorders) Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09105 Amino acid metabolism    00250 Alanine, aspartate and glutamate metabolism     435 (ASL)    00220 Arginine biosynthesis     435 (ASL)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:hsa04147]     435 (ASL) Enzymes [BR:hsa01000]  4. Lyases   4.3  Carbon-nitrogen lyases    4.3.2  Amidine-lyases     4.3.2.1  argininosuccinate lyase      435 (ASL) Exosome [BR:hsa04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    435 (ASL) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Lyase_1 ASL_C2 T4SS_CagC Motif Other DBs NCBI-GeneID:  435 NCBI-ProteinID:  NP_000039 OMIM:  608310 HGNC:  746 Ensembl:  ENSG00000126522 UniProt:  P04424 A0A024RDL8 Structure PDB LinkDB All DBs Position 7:66075819..66093576 Genome browser AA seq 464 aa AA seqDB search MASESGKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEM DQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTD LRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVAL TRDSERLLEVRKRINVLPLGSGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVA EFLFWASLCMTHLSRMAEDLILYCTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKA GRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMSAVLQVATGVISTLQIHQENM GQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNQLSLQELQTISPLF SGDVICVWDYGHSVEQYGALGGTARSSVDWQIRQVRALLQAQQA NT seq 1395 nt NT seq  +upstreamnt  +downstreamnt atggcctcggagagtgggaagctttggggtggccggtttgtgggtgcagtggaccccatc atggagaagttcaacgcgtccattgcctacgaccggcacctttgggaggtggatgttcaa ggcagcaaagcctacagcaggggcctggagaaggcagggctcctcaccaaggccgagatg gaccagatactccatggcctagacaaggtggctgaggagtgggcccagggcaccttcaaa ctgaactccaatgatgaggacatccacacagccaatgagcgccgcctgaaggagctcatt ggtgcaacggcagggaagctgcacacgggacggagccggaatgaccaggtggtcacagac ctcaggctgtggatgcggcagacctgctccacgctctcgggcctcctctgggagctcatt aggaccatggtggatcgggcagaggcggaacgtgatgttctcttcccggggtacacccat ttgcagagggcccagcccatccgctggagccactggattctgagccacgccgtggcactg acccgagactctgagcggctgctggaggtgcggaagcggatcaatgtcctgcccctgggg agtggggccattgcaggcaatcccctgggtgtggaccgagagctgctccgagcagaactc aactttggggccatcactctcaacagcatggatgccactagtgagcgggactttgtggcc gagttcctgttctgggcttcgctgtgcatgacccatctcagcaggatggccgaggacctc atcctctactgcaccaaggaattcagcttcgtgcagctctcagatgcctacagcacggga agcagcctgatgccccagaagaaaaaccccgacagtttggagctgatccggagcaaggct gggcgtgtgtttgggcggtgtgccgggctcctgatgaccctcaagggacttcccagcacc tacaacaaagacttacaggaggacaaggaagctgtgtttgaagtgtcagacactatgagt gccgtgctccaggtggccactggcgtcatctctacgctgcagattcaccaagagaacatg ggacaggctctcagccccgacatgctggccactgaccttgcctattacctggtccgcaaa gggatgccattccgccaggcccacgaggcctccgggaaagctgtgttcatggccgagacc aagggggtcgccctcaaccagctgtcactgcaggagctgcagaccatcagccccctgttc tcgggcgacgtgatctgcgtgtgggactacgggcacagtgtggagcagtatggtgccctg ggcggcactgcgcgctccagcgtcgactggcagatccgccaggtgcgggcgctactgcag gcacagcaggcctag

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