Homo sapiens (human): 445 Help Entry 445               CDS       T01001                                  Symbol ASS1, ASS, CTLN1 Name (RefSeq) argininosuccinate synthase 1   KO K01940   argininosuccinate synthase [EC:6.3.4.5] Organism hsa  Homo sapiens (human) Pathway hsa00220   Arginine biosynthesis hsa00250   Alanine, aspartate and glutamate metabolism hsa01100   Metabolic pathways hsa01230   Biosynthesis of amino acids hsa05418   Fluid shear stress and atherosclerosis Module hsa_M00029   Urea cycle hsa_M00844   Arginine biosynthesis, ornithine => arginine Network nt06010  Urea cycle   Element N00593   Urea cycle Disease H00185   Citrullinemia H01398   Primary hyperammonemia (Urea cycle disorders) Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09105 Amino acid metabolism    00250 Alanine, aspartate and glutamate metabolism     445 (ASS1)    00220 Arginine biosynthesis     445 (ASS1)  09160 Human Diseases   09166 Cardiovascular disease    05418 Fluid shear stress and atherosclerosis     445 (ASS1)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:hsa04147]     445 (ASS1) Enzymes [BR:hsa01000]  6. Ligases   6.3  Forming carbon-nitrogen bonds    6.3.4  Other carbon-nitrogen ligases     6.3.4.5  argininosuccinate synthase      445 (ASS1) Exosome [BR:hsa04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    445 (ASS1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Arginosuc_syn_C Arginosuc_synth QueC DUF7411 tRNA_Me_trans Cupin_NOL9 Motif Other DBs NCBI-GeneID:  445 NCBI-ProteinID:  NP_000041 OMIM:  603470 HGNC:  758 Ensembl:  ENSG00000130707 UniProt:  P00966 Q5T6L4 Structure PDBPDBj LinkDB All DBs Position 9:130444707..130501274 Genome browser AA seq 412 aa AA seqDB search MSSKGSVVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQKEDFEEARKKALKLGAKKVF IEDVSREFVEEFIWPAIQSSALYEDRYLLGTSLARPCIARKQVEIAQREGAKYVSHGATG KGNDQVRFELSCYSLAPQIKVIAPWRMPEFYNRFKGRNDLMEYAKQHGIPIPVTPKNPWS MDENLMHISYEAGILENPKNQAPPGLYTKTQDPAKAPNTPDILEIEFKKGVPVKVTNVKD GTTHQTSLELFMYLNEVAGKHGVGRIDIVENRFIGMKSRGIYETPAGTILYHAHLDIEAF TMDREVRKIKQGLGLKFAELVYTGFWHSPECEFVRHCIAKSQERVEGKVQVSVLKGQVYI LGRESPLSLYNEELVSMNVQGDYEPTDATGFININSLRLKEYHRLQSKVTAK NT seq 1239 nt NT seq  +upstreamnt  +downstreamnt atgtccagcaaaggctccgtggttctggcctacagtggcggcctggacacctcgtgcatc ctcgtgtggctgaaggaacaaggctatgacgtcattgcctatctggccaacattggccag aaggaagacttcgaggaagccaggaagaaggcactgaagcttggggccaaaaaggtgttc attgaggatgtcagcagggagtttgtggaggagttcatctggccggccatccagtccagc gcactgtatgaggaccgctacctcctgggcacctctcttgccaggccctgcatcgcccgc aaacaagtggaaatcgcccagcgggagggggccaagtatgtgtcccacggcgccacagga aaggggaacgatcaggtccggtttgagctcagctgctactcactggccccccagataaag gtcattgctccctggaggatgcctgaattctacaaccggttcaagggccgcaatgacctg atggagtacgcaaagcaacacgggattcccatcccggtcactcccaagaacccgtggagc atggatgagaacctcatgcacatcagctacgaggctggaatcctggagaaccccaagaac caagcgcctccaggtctctacacgaagacccaggacccagccaaagcccccaacacccct gacattctcgagatcgagttcaaaaaaggggtccctgtgaaggtgaccaacgtcaaggat ggcaccacccaccagacctccttggagctcttcatgtacctgaacgaagtcgcgggcaag catggcgtgggccgtattgacatcgtggagaaccgcttcattggaatgaagtcccgaggt atctacgagaccccagcaggcaccatcctttaccatgctcatttagacatcgaggccttc accatggaccgggaagtgcgcaaaatcaaacaaggcctgggcttgaaatttgctgagctg gtgtataccggtttctggcacagccctgagtgtgaatttgtccgccactgcatcgccaag tcccaggagcgagtggaagggaaagtgcaggtgtccgtcctcaagggccaggtgtacatc ctcggccgggagtccccactgtctctctacaatgaggagctggtgagcatgaacgtgcag ggtgattatgagccaactgatgccaccgggttcatcaacatcaattccctcaggctgaag gaatatcatcgtctccagagcaaggtcactgccaaatag

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