Homo sapiens (human): 4619
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Entry
4619 CDS
T01001
Symbol
MYH1, HEL71, MYHSA1, MYHa, MyHC-2X/D, MyHC-2x
Name
(RefSeq) myosin heavy chain 1
KO
K24220
myosin heavy chain 1/2/3/4/8/13/7B/15
Organism
hsa
Homo sapiens (human)
Pathway
hsa04814
Motor proteins
hsa04820
Cytoskeleton in muscle cells
Network
nt06539
Cytoskeleton in muscle cells
Element
N01817
Myosin thick filament
N01818
Actin thin filament, muscle contraction
Drug target
Sevasemten:
D12902
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09142 Cell motility
04814 Motor proteins
4619 (MYH1)
04820 Cytoskeleton in muscle cells
4619 (MYH1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
hsa04812
]
4619 (MYH1)
Cytoskeleton proteins [BR:
hsa04812
]
Eukaryotic cytoskeleton proteins
Actin filaments / Microfilaments
Actin-binding proteins
Myosins
4619 (MYH1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Myosin_head
Myosin_tail_1
Myosin_N
OVT1
IQ
Crescentin
NPHP3_N
AAA_22
Motif
Other DBs
NCBI-GeneID:
4619
NCBI-ProteinID:
NP_005954
OMIM:
160730
HGNC:
7567
Ensembl:
ENSG00000109061
UniProt:
P12882
LinkDB
All DBs
Position
17:complement(10492307..10518542)
Genome browser
AA seq
1939 aa
AA seq
DB search
MSSDSEMAIFGEAAPFLRKSERERIEAQNKPFDAKTSVFVVDPKESFVKATVQSREGGKV
TAKTEAGATVTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG
LFCVTVNPYKWLPVYNAEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE
SGAGKTVNTKRVIQYFATIAVTGEKKKEEVTSGKMQGTLEDQIISANPLLEAFGNAKTVR
NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDL
IEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIEILGFTSDERVSIYKLTGAVM
HYGNMKFKQKQREEQAEPDGTEVADKAAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTV
QQVYNAVGALAKAVYDKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC
INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE
CMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKN
KDPLNETVVGLYQKSAMKTLALLFVGATGAEAEAGGGKKGGKKKGSSFQTVSALFRENLN
KLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYA
DFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEM
RDEKLAQLITRTQAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKI
KPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEAD
SLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDD
LELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDK
VNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQL
DEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQR
SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKH
ADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQL
SEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELK
RQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYE
TDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTN
AACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLE
TLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEG
KILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKK
KMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVER
RANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQ
IQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHR
LDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEE
DRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQ
VNKLRVKSREVHTKIISEE
NT seq
5820 nt
NT seq
+upstream
nt +downstream
nt
atgagttccgactctgagatggccatttttggggaggctgctcctttcctccgaaagtct
gaaagggagcgaattgaagcccagaacaagccttttgatgccaagacatcagtctttgtg
gtggaccctaaggagtcctttgtgaaagcaacagtgcagagcagggaaggggggaaggtg
acagctaagaccgaagctggagctactgtaacagtgaaagatgaccaagtcttccccatg
aaccctcccaaatatgacaagatcgaggacatggccatgatgactcatctacacgagcct
gctgtgctgtacaacctcaaagagcgctacgcagcctggatgatctacacctactcaggc
ttgttctgtgtcactgtcaacccctacaagtggttgccagtgtataatgcagaggtggtg
acagcctaccgaggcaaaaagcgccaggaggccccaccccacatcttctccatctctgac
aatgcctatcagttcatgctgactgatcgggagaatcagtctatcttgatcaccggagaa
tctggcgcagggaagactgtgaacaccaagcgtgtcatccagtactttgcaacaattgca
gttactggggagaagaagaaggaagaagttacttctggcaaaatgcaggggactctggaa
gatcaaatcatcagtgccaaccccctactggaggcctttggcaacgccaagaccgtgagg
aatgacaactcctctcgctttggtaaattcatcaggatccacttcggtaccacagggaaa
ctggcttctgctgatattgaaacatatcttctggagaagtctagagttactttccagcta
aaggctgaaagaagctatcatattttttatcagatcatgtctaacaagaagccagatcta
attgaaatgctcctgatcaccaccaacccatacgattatgccttcgtcagtcaaggggag
atcacagtgcccagcattgatgaccaagaagagttgatggctacagatagtgccattgaa
attctgggctttacttcagatgaaagagtgtccatctataagctcacaggggctgtgatg
cattatgggaacatgaaattcaagcaaaagcagcgtgaggagcaagctgagccagatggc
actgaagttgctgacaaggcagcctatctccaaaatctgaactctgcagatctgctcaaa
gccctctgctaccctagggtcaaggtcggcaatgagtatgtcaccaaaggtcaaactgtg
cagcaggtgtacaatgcagtgggtgctctggccaaagctgtctacgataagatgttcttg
tggatggtcacccgcatcaaccagcagctggacaccaagcagcccaggcagtacttcatt
ggggtcttggacattgctggctttgagatctttgatttcaacagcctggagcagctgtgc
atcaacttcaccaatgagaaactgcaacagtttttcaaccaccacatgttcgtgctggag
caggaggagtacaagaaggaaggcattgagtggacgttcattgactttgggatggacctg
gctgcctgcatcgagctcatcgagaagcctatgggcatcttctccatcctggaagaggag
tgcatgttccccaaggcgacagacacctccttcaagaacaagctgtatgaacaacatctt
ggaaaatccaataacttccagaagcccaagcctgccaaaggcaagcctgaggcccacttc
tctttgattcactatgctggcaccgtggactacaacattgccggctggcttgacaagaac
aaggaccccctgaatgagactgtggtggggctgtaccagaagtctgcaatgaagactctg
gctctcctctttgttggggcaacgggagcggaagcagaggctggcggtggaaagaaaggt
ggtaagaagaagggttcttctttccagactgtgtctgctctcttcagggagaatttgaat
aagctgatgaccaacttgaggagcactcacccccactttgtgcggtgcatcatccccaat
gaaactaaaactcctggtgccatggagcatgagcttgtcctgcatcagctgaggtgtaac
ggtgtgctggaaggcatccgcatctgcaggaaaggcttcccaagcagaatcctttatgca
gacttcaaacagagatacaaggtgttaaatgcaagtgctatccctgaaggacaattcatc
gatagcaagaaggcttcagagaagctcctggggtccattgacattgaccacacccagtat
aaatttggtcacaccaaggtctttttcaaagctggtcttctggggctcctagaggagatg
cgagatgagaagctggcccagctgattacccgaacccaggccatgtgcagagggttcttg
gcaagagtggagtaccagaaaatggtggaaagaagagagtccatcttctgcatccagtac
aatgtccgtgccttcatgaatgtgaagcactggccctggatgaagctgtatttcaagatc
aaacccctcctcaaaagtgcagagacagagaaggagatggccaacatgaaggaagaattt
gagaaaaccaaagaagagctggctaagaccgaggcaaaaaggaaagagctggaagaaaaa
atggttactctgatgcaagaaaaaaatgacttgcaactccaggttcaagctgaagctgac
agcttggctgatgcagaggaaaggtgtgaccagctaatcaaaaccaaaatccagctagaa
gccaaaatcaaagaggtgactgagagagctgaggatgaggaagagatcaatgctgagctg
acagccaagaagaggaaactggaggatgaatgttcagaactcaagaaagacattgatgac
cttgagctgacactggccaaggttgagaaggagaaacatgccacagaaaacaaggtgaaa
aacctcacagaagagatggcgggtctggatgaaaccattgctaagctgaccaaggagaag
aaggctctccaggaggcccaccagcagaccctggatgacctgcaggcagaggaggacaaa
gtcaacaccctgaccaaagctaaaatcaaacttgaacaacaagtggatgatcttgaagga
tctttggaacaagaaaagaaaatccggatggatctagaaagagcaaagagaaaactagag
ggagacctaaaattggctcaagaatccacaatggatatagaaaatgacaaacaacaactt
gatgaaaagcttaaaaagaaagagtttgaaatgagcggtctgcaaagcaagattgaagat
gaacaagcccttggtatgcagctgcagaagaaaatcaaggagttacaagcccgcattgag
gagctggaggaggaaatcgaggcagagcgggcctcccgggccaaagcagagaagcagcgc
tctgatctctcccgggagctggaggagatcagcgagaggctggaagaagccggtggggcc
acctcagcccagattgagatgaacaagaagcgggaggctgagttccagaaaatgcgcagg
gacctggaggaggccaccctacagcatgaagccacggcggccaccctgaggaagaagcat
gcagatagtgtggccgagcttggggagcagattgacaacctgcagcgagtgaagcagaag
ctggagaaggagaagagtgagatgaagatggagatcgatgaccttgctagtaacatggag
actgtctccaaagccaagggaaaccttgaaaagatgtgccgcgctctagaagatcaactg
agtgaaattaagaccaaggaagaggagcagcagcggctgatcaatgacctcacagcacag
agagcgcgcctgcaaacagaatcaggtgaatattcacgccagctagatgaaaaggacaca
ctagtttcacagctctcgaggggcaaacaagcctttacacaacagattgaggaactgaaa
aggcaacttgaagaggagataaaggccaagagtgccctggcacatgccctgcagtcctcc
cgccatgactgtgacctgctgcgggaacagtatgaggaggagcaggaagccaaggccgag
ctacagagagcaatgtccaaggccaacagtgaggttgcccagtggaggaccaaatatgag
acagatgccatccagcgcacagaggagctggaggaggccaagaagaagctggctcagcgt
ctgcaggatgctgaggaacatgtagaagctgtgaatgccaaatgtgcttcccttgagaag
acgaagcagaggctccagaatgaagttgaggacctcatgattgatgttgagaggacaaat
gctgcctgtgccgccctggacaaaaagcaaaggaactttgataagatcctggcagaatgg
aaacagaagtgtgaagaaactcatgctgaacttgaagcttctcaaaaggaatcccgctca
ctcagcacagaactatttaagattaagaatgcttatgaggaatctttagaccaacttgaa
accttgaaacgggaaaataagaatttgcaacaggagatttctgatctcactgaacagatt
gcagaaggaggaaagcgcatccatgaactggaaaaaataaagaagcaagttgagcaagaa
aagtctgaacttcaggctgccttagaggaggcagaggcatctcttgaacatgaagaggga
aagatcctgcgcatccagcttgagttgaaccaagtcaagtctgaggttgataggaaaatt
gctgaaaaagatgaggaaattgaccagatgaagagaaaccacattagaatcgtggagtcc
atgcagagcacactggatgctgagatcaggagcaggaatgatgccattaggctcaagaag
aagatggagggagacctcaatgaaatggaaatccagctgaaccatgccaaccgcatggct
gctgaggccctgaggaactataggaacacccaagccatcctcaaggatacccagctccac
ctggatgatgctctccggagccaggaggacctgaaggaacagctggctatggtggagcgc
agagccaacctgctgcaggctgagatcgaggagctgcgggccactctggaacagacagag
aggagcaggaaaatcgcagaacaggagctcctggatgccagtgagcgtgttcagctcctg
cacacccagaacaccagcctgatcaacaccaagaagaagctggagacagacatttcccaa
atccagggagagatggaagacatcatccaggaagcccgcaatgcagaagagaaggccaag
aaggccatcactgatgctgccatgatggctgaggagctgaagaaggaacaggacaccagc
gcccatctggagcggatgaagaagaacctggaacagacggtgaaggacctgcagcatcgt
ctggatgaggctgagcagctggccctgaagggtgggaagaagcagatccagaaactggag
gccagggttcgtgaacttgaaggtgaagttgaaagtgaacagaagcgcaatgttgaagct
gtcaagggtctacgcaaacatgagagaaaagtgaaggaactcacttaccaaactgaggaa
gaccgcaagaatattctcaggctccaggacctggtggacaaactgcaagcaaaggtgaaa
tcctacaagagacaagctgaagaagcggaggaacaatccaacgtcaacctctccaaattc
cgcaggatccagcacgagctggaggaggccgaggaacgggctgacattgctgagtcccag
gtcaacaagctgagggtgaagagcagggaggttcacacaaaaatcataagtgaagagtaa
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integrated database retrieval system
