| Entry |
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| Symbol |
MYH3, CPSFS1A, CPSFS1B, CPSKF1A, CPSKF1B, DA2A, DA2B, DA2B3, DA8, HEMHC, MYHC-EMB, MYHSE1, SMHCE
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| Name |
(RefSeq) myosin heavy chain 3
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| KO |
| K24220 | myosin heavy chain 1/2/3/4/8/13/7B/15 |
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| Organism |
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| Pathway |
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| Network |
nt06539 Cytoskeleton in muscle cells |
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| Element |
| N01818 | Actin thin filament, muscle contraction |
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| Disease |
| H02717 | Contractures, pterygia, and spondylocarpotarsal fusion syndrome |
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| Drug target |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09140 Cellular Processes
09142 Cell motility
04814 Motor proteins
4621 (MYH3)
04820 Cytoskeleton in muscle cells
4621 (MYH3)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:hsa04812]
4621 (MYH3)
Cytoskeleton proteins [BR:hsa04812]
Eukaryotic cytoskeleton proteins
Actin filaments / Microfilaments
Actin-binding proteins
Myosins
4621 (MYH3)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
17:complement(10628532..10678417)
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| AA seq |
1940 aa
MSSDTEMEVFGIAAPFLRKSEKERIEAQNQPFDAKTYCFVVDSKEEYAKGKIKSSQDGKV
TVETEDNRTLVVKPEDVYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKDRYTSWMIYTYSG
LFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE
SGAGKTVNTKRVIQYFATIAATGDLAKKKDSKMKGTLEDQIISANPLLEAFGNAKTVRND
NSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELIE
LLLITTNPYDYPFISQGEILVASIDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVMHY
GNMKFKQKQREEQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQ
VHHAVNALSKSVYEKLFLWMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLCIN
FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECM
FPKATDTSFKNKLYDQHLGKSNNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKD
PLNETVVGLYQKSSNRLLAHLYATFATADADSGKKKVAKKKGSSFQTVSALFRENLNKLM
SNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFK
QRYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDD
RLAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKIKPL
LKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLL
DAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLEL
TLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNS
LNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDER
LKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDY
ARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADS
VAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEA
RGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQL
EEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDA
IQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLA
AALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVK
RENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKIL
RIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKME
GDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRAN
LLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQS
EVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDE
AEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRK
NVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNK
LRAKTRDFTSSRMVVHESEE |
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| NT seq |
5823 nt +upstreamnt +downstreamnt
atgagtagtgacactgaaatggaagtgttcggcatagctgctcctttcctccggaagtca
gaaaaggagaggatcgaggctcagaaccagccctttgatgccaagacgtattgcttcgtg
gtggactcaaaggaagaatatgccaaggggaaaatcaagagttctcaggatgggaaggtc
actgtggaaactgaggacaacaggaccctggtggtcaaaccagaggatgtgtacgccatg
aacccccccaagttcgacaggatcgaagacatggccatgctgacgcacctgaatgagcca
gccgtgctgtacaacctgaaggaccgttacacatcttggatgatctatacctactcaggc
ctcttctgtgtcactgtcaacccctacaagtggctgccggtgtacaaccccgaggtggtg
gaaggctaccgaggcaaaaagcgccaggaggccccaccccacatcttctccatctctgac
aacgcctatcagttcatgctgactgatcgtgaaaaccagtccattctgatcaccggagaa
tccggggcaggaaagactgtgaacaccaaacgggtcatccagtactttgcaacaattgca
gctactggggacctggccaagaagaaggactccaaaatgaaggggactctggaagatcaa
atcatcagtgccaatcccctgctggaggcctttgggaacgccaagactgtgaggaatgac
aactcctcccgttttggcaagttcatccgaatccattttggaaccactgggaagctggcc
tctgcagatattgaaacttatcttctggaaaaatcaagagtcactttccagctgaaggct
gaaagaagctaccacatcttctaccagattctttctaacaagaagcctgagctcatagag
ctgctgcttattacgaccaacccttacgactacccgttcattagccagggggagatcctg
gtggccagcatagatgatgcagaggagctgctggctacagacagcgccattgacatcctg
ggcttcaccccagaagagaaatctgggctctacaagctgacgggagccgtgatgcactac
gggaacatgaagttcaagcagaagcagcgagaggagcaggccgagccggatggcacagaa
gtggctgacaaaacagcctatctgatgggcctgaactcttcggacctcctaaaagctttg
tgctttcctagagtgaaagttgggaatgagtacgttaccaaaggtcaaactgtggatcag
gttcaccatgctgtgaatgctctttcaaaatcagtttatgaaaagttgttcttgtggatg
gtcactcgcattaaccagcaactggatacgaagcttccaagacaacacttcattggtgtt
ttggacattgcaggctttgaaatctttgagtataacagcctggagcagctgtgcatcaac
ttcaccaatgagaaactgcaacagtttttcaaccaccacatgttcgtgctggagcaggag
gagtacaagaaggaaggcatcgagtggacgttcattgacttcgggatggacctggctgcc
tgcatcgagctcatcgagaagcctatgggcatcttctccatcctggaagaggagtgcatg
ttccccaaggcaacagacacctccttcaagaacaagctgtatgaccagcatcttggaaag
tccaacaacttccagaagcccaaggtggtcaaaggcagggccgaggctcacttctcactg
atccactatgcgggcaccgtggactacagtgtctcaggttggctggagaagaacaaggac
cctctgaacgagactgtggttgggctgtaccagaagtcttccaacaggctcctggcacac
ctctatgccacgtttgccacggcggatgctgacagtggaaagaagaaagttgccaagaag
aagggttcttccttccaaactgtctctgcccttttcagggaaaacctgaacaagctgatg
tcaaatttaagaactactcaccctcattttgtgcgttgtataattcccaatgaaaccaaa
actccaggggctatggaacacagccttgttctgcaccagctgcggtgtaacggtgtcctg
gagggcatccgcatctgcaggaaagggttcccaaacaggattctctatggcgattttaaa
caaagataccgagtgctgaatgccagtgcaatccctgagggacaattcattgacagcaag
aaagcctgtgaaaagcttctggcatccattgatattgaccacactcagtacaaatttgga
cataccaaggtgttcttcaaggctggcttgctgggaaccctggaagagatgcgggatgac
cgcctggccaaactaatcacccggacacaagctgtgtgcagagggttcctcatgcgtgtg
gaattccagaagatggtgcagaggagggagtccatcttctgcatccagtacaacattcgc
tcattcatgaacgtcaagcactggccctggatgaaactcttcttcaagatcaagcccctc
ctcaagagtgcagagactgagaaagagatggccaccatgaaggaagaattccagaaaacc
aaagatgaactcgccaagtcggaggcaaaaaggaaggagctagaggaaaaactggtgact
ctggtccaagagaagaatgacctgcagctccaagtacaagctgaaagcgaaaatttgttg
gatgctgaggaaagatgcgatcagctgatcaaagccaaattccagctcgaggccaagatc
aaggaggtgacagagagagctgaagatgaggaggagatcaatgctgagctgacggccaag
aagaggaaactggaggatgaatgctcagagctcaagaaagacattgatgaccttgagttg
accctggccaaggttgagaaggagaagcatgccacagagaacaaggttaaaaaccttact
gaggaactctctgggttagatgaaacaattgcaaagttaaccagagagaagaaggccctc
caagaggcgcaccagcaggccttggatgacctccaagctgaagaagacaaagtcaattct
ttgaacaaaaccaagagcaaactggaacagcaagtggaagacctggaaagctccctagaa
caagaaaagaagctccgagtagacctggaaaggaacaaaaggaaattggaaggagacttg
aagcttgctcaagagtccatattagatctggagaatgacaagcaacagctggacgaaagg
ctcaagaagaaagattttgaatattgtcaacttcaaagcaaagtggaagatgagcagaca
ctgggcctccagtttcagaagaaaatcaaagagttgcaggctcgaattgaggagctggaa
gaggagatagaggcggagagggccacccgcgcgaagacagagaaacagcgcagcgactat
gcccgggagctggaggagctgagcgagcggctggaggaggcgggaggcgtcacctccacg
cagatagagctcaacaagaagcgggaggcggagttcctgaagctgcgcagggacctggag
gaggccacactgcagcacgaagccatggtggccgcgctgaggaagaagcatgcggatagt
gtggccgagcttggggagcagattgacaacctgcagcgggtcaagcagaagctggagaag
gagaagagcgagttcaagctggagatcgatgacctctccagcagcatggagagtgtgtcg
aaatctaaggcaaatctggaaaaaatctgccgaaccctggaggatcagttaagtgaggcc
aggggcaagaatgaggaaattcagaggagcctgagcgagctgaccacacagaagtctcgt
ttgcagaccgaggctggtgagctgagtcgtcagctggaagaaaaagaaagcatagtatcc
caactttccaggagcaagcaagcctttacccagcaaacagaagagctcaagaggcagctg
gaggaagagaacaaggccaagaacgccctggcgcacgccctgcagtcctcccgccacgac
tgtgacctgctgcgggaacagtatgaggaggagcaggaaggcaaagctgagctgcagagg
gcgctgtccaaggccaatagtgaggttgcccagtggagaaccaaatacgagacggacgcc
atccagcgcacagaagagctggaggaggccaagaaaaaacttgctcagcgccttcaagat
tccgaggaacaggttgaggcagtgaatgctaaatgtgcttcactggagaagaccaagcag
aggctgcaaggagaggtggaggatctgatggttgatgttgaaagagccaattccttggcc
gccgctctggacaagaagcagaggaactttgacaaggtgttggcagagtggaagacaaag
tgtgaggagagccaagcagagctggaggcatccctgaaggagtcccgctccttgagcact
gagctcttcaaactgaaaaatgcctacgaggaagccttagatcaacttgaaactgtgaaa
cgggaaaataagaacttagagcaggagatagcagatctcacagaacaaattgctgaaaat
ggcaaaaccatccatgaactggagaaatcaagaaagcagattgagctggaaaaggctgat
atccagctggctctcgaggaagcagaggctgctcttgagcatgaagaagccaagatcctc
cgaatccagcttgaattgacacaagtgaaatcagaaattgatagaaagatcgccgagaag
gatgaagagatcgagcagctgaagaggaactaccagagaacagtggaaaccatgcagagc
gccctggacgccgaggtgcggagcaggaatgaagccatccggctcaagaagaagatggag
ggggacctgaatgaaatcgagatccagctgagccacgccaaccgccaggcggcggagacc
ctcaaacacctcaggagtgtccagggacagctgaaggatacgcagctccacctggatgat
gccctccggggccaggaggacctgaaggagcagctggcgattgtggagcgcagagccaac
ctgctgcaggccgaggtggaggagctgcgggctactctggagcagacggagagggcccgg
aaactggcggaacaggagctcctggactccaacgagagggtgcagctgctgcatacccag
aacaccagcctcatccacaccaagaagaagctggagacagacctcatgcagctccagagt
gaggtagaagatgccagcagggatgcaaggaacgctgaggagaaggccaagaaggccatc
acggacgctgccatgatggcggaggagctgaagaaggagcaggacaccagcgcccacctt
gagcggatgaagaagaacctggaacagacggtgaaggacctgcagcatcgtctagatgag
gccgagcagctggcgctgaagggcgggaagaagcagatccagaaactggagaccaggatc
cgagagctggagtttgaacttgagggagagcagaagaagaacacagagtctgttaagggc
ctgaggaagtatgagcggagggtcaaggagctgacgtaccagagtgaagaggacaggaag
aatgtgctgagattgcaggatctggtggataaactgcaagtgaaagtcaagtcctacaag
aggcaggcggaggaggctgatgaacaagccaatgctcatctcaccaaattccgaaaggct
cagcatgagctggaggaggccgaggaacgtgcggatatcgcagaatctcaagtcaacaag
ctccgcgctaagactcgagacttcacctccagcaggatggtggtccacgagagtgaagag
tga |
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