Homo sapiens (human): 4627
Help
Entry
4627 CDS
T01001
Symbol
MYH9, BDPLT6, DFNA17, EPSTS, FTNS, MATINS, MHA, NMHC-II-A, NMMHC-IIA, NMMHCA
Name
(RefSeq) myosin heavy chain 9
KO
K10352
myosin heavy chain 9/10/11/14
Organism
hsa
Homo sapiens (human)
Pathway
hsa04270
Vascular smooth muscle contraction
hsa04530
Tight junction
hsa04810
Regulation of actin cytoskeleton
hsa04814
Motor proteins
hsa04820
Cytoskeleton in muscle cells
hsa05130
Pathogenic Escherichia coli infection
Disease
H00233
MYH9-related disease
H00578
Epstein syndrome
H00604
Deafness, autosomal dominant
H01740
Macrothrombocytopenia
H02051
May-Hegglin anomaly
H02052
Sebastian syndrome
H02053
Fechtner syndrome
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09144 Cellular community - eukaryotes
04530 Tight junction
4627 (MYH9)
09142 Cell motility
04814 Motor proteins
4627 (MYH9)
04820 Cytoskeleton in muscle cells
4627 (MYH9)
04810 Regulation of actin cytoskeleton
4627 (MYH9)
09150 Organismal Systems
09153 Circulatory system
04270 Vascular smooth muscle contraction
4627 (MYH9)
09160 Human Diseases
09171 Infectious disease: bacterial
05130 Pathogenic Escherichia coli infection
4627 (MYH9)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
hsa04812
]
4627 (MYH9)
04147 Exosome [BR:
hsa04147
]
4627 (MYH9)
Cytoskeleton proteins [BR:
hsa04812
]
Eukaryotic cytoskeleton proteins
Actin filaments / Microfilaments
Actin-binding proteins
Myosins
4627 (MYH9)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of bladder cancer cells
4627 (MYH9)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Myosin_tail_1
Myosin_head
Myosin_N
IQ
ADIP
CC2-LZ
ERM_helical
AAA_22
Motif
Other DBs
NCBI-GeneID:
4627
NCBI-ProteinID:
NP_002464
OMIM:
160775
HGNC:
7579
Ensembl:
ENSG00000100345
UniProt:
P35579
Structure
PDB
LinkDB
All DBs
Position
22:complement(36281280..36387967)
Genome browser
AA seq
1960 aa
AA seq
DB search
MAQQAADKYLYVDKNFINNPLAQADWAAKKLVWVPSDKSGFEPASLKEEVGEEAIVELVE
NGKKVKVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVV
INPYKNLPIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGK
TENTKKVIQYLAYVASSHKSKKDQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIR
INFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKY
RFLSNGHVTIPGQQDKDMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNT
DQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKA
TYERMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLF
NHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDK
SFVEKVMQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLL
HQSSDKFVSELWKDVDRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMAT
LRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQR
YEILTPNSIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKIT
DVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQV
SRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAE
ELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQ
KLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAK
LKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAK
KEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEE
LEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEE
LAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVK
FNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEE
NRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCL
ETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLE
KKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNK
QFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEV
NLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLK
DLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEA
EMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEE
EQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGT
VKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQ
YKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNK
LRRGDLPFVVPRRMARKGAGDGSDEEVDGKADGAEAKPAE
NT seq
5883 nt
NT seq
+upstream
nt +downstream
nt
atggcacagcaagctgccgataagtatctctatgtggataaaaacttcatcaacaatccg
ctggcccaggccgactgggctgccaagaagctggtatgggtgccttccgacaagagtggc
tttgagccagccagcctcaaggaggaggtgggcgaagaggccatcgtggagctggtggag
aatgggaagaaggtgaaggtgaacaaggatgacatccagaagatgaacccgcccaagttc
tccaaggtggaggacatggcagagctcacgtgcctcaacgaagcctcggtgctgcacaac
ctcaaggagcgttactactcagggctcatctacacctattcaggcctgttctgtgtggtc
atcaatccttacaagaacctgcccatctactctgaagagattgtggaaatgtacaagggc
aagaagaggcacgagatgccccctcacatctatgccatcacagacaccgcctacaggagt
atgatgcaagaccgagaagatcaatccatcttgtgcactggtgaatctggagctggcaag
acggagaacaccaagaaggtcatccagtatctggcgtacgtggcgtcctcgcacaagagc
aagaaggaccagggcgagctggagcggcagctgctgcaggccaaccccatcctggaggcc
ttcgggaacgccaagaccgtgaagaatgacaactcctcccgcttcggcaaattcattcgc
atcaactttgatgtcaatggctacattgttggagccaacattgagacttatcttttggag
aaatctcgtgctatccgccaagccaaggaagaacggaccttccacatcttctattatctc
ctgtctggggctggagagcacctgaagaccgatctcctgttggagccgtacaacaaatac
cgcttcctgtccaatggacacgtcaccatccccgggcagcaggacaaggacatgttccag
gagaccatggaggccatgaggattatgggcatcccagaagaggagcaaatgggcctgctg
cgggtcatctcaggggttcttcagctcggcaacatcgtcttcaagaaggagcggaacact
gaccaggcgtccatgcccgacaacacagctgcccaaaaggtgtcccatctcttgggtatc
aatgtgaccgatttcaccagaggaatcctcaccccgcgcatcaaggtgggacgggattac
gtccagaaggcgcagactaaagagcaggctgactttgccatcgaggccttggccaaggcg
acctatgagcggatgttccgctggctggtgctgcgcatcaacaaggctctggacaagacc
aagaggcagggcgcctccttcatcgggatcctggacattgccggcttcgagatctttgat
ctgaactcgtttgagcagctgtgcatcaattacaccaatgagaagctgcagcagctcttc
aaccacaccatgttcatcctggagcaggaggagtaccagcgcgagggcatcgagtggaac
ttcatcgactttggcctcgacctgcagccctgcatcgacctcattgagaagccagcaggc
cccccgggcattctggccctgctggacgaggagtgctggttccccaaagccaccgacaag
agcttcgtggagaaggtgatgcaggagcagggcacccaccccaagttccagaagcccaag
cagctgaaggacaaagctgatttctgcattatccactatgccggcaaggtggattacaaa
gctgacgagtggctgatgaagaacatggatcccctgaatgacaacatcgccacactgctc
caccagtcctctgacaagtttgtctcggagctgtggaaggatgtggaccgcatcatcggc
ctggaccaggtggccggcatgtcggagaccgcactgcccggggccttcaagacgcggaag
ggcatgttccgcactgtggggcagctttacaaggagcagctggccaagctgatggctacg
ctgaggaacacgaaccccaactttgtccgctgcatcatccccaaccacgagaagaaggcc
ggcaagctggacccgcatctcgtgctggaccagctgcgctgcaacggtgttctcgagggc
atccgtatctgccgccagggcttccccaacagggtggtcttccaggagtttcggcagaga
tatgagatcctgactccaaactccattcccaagggtttcatggacgggaagcaggcgtgc
gtgctcatgataaaagccctggagctcgacagcaatctgtaccgcattggccagagcaaa
gtcttcttccgtgccggtgtgctggcccacctggaggaggagcgagacctgaagatcacc
gacgtcatcatagggttccaggcctgctgcaggggctacctggccaggaaagcatttgcc
aagcggcagcagcagcttaccgccatgaaggtcctccagcggaactgcgctgcctacctg
aagctgcggaactggcagtggtggcggctcttcaccaaggtcaagccgctgctgcaggtg
agccggcaggaggaggagatgatggccaaggaggaggagctggtgaaggtcagagagaag
cagctggctgcggagaacaggctcacggagatggagacgctgcagtctcagctcatggca
gagaaattgcagctgcaggagcagctccaggcagaaaccgagctgtgtgccgaggctgag
gagctccgggcccgcctgaccgccaagaagcaggaattagaagagatctgccatgaccta
gaggccagggtggaggaggaggaggagcgctgccagcacctgcaggcggagaagaagaag
atgcagcagaacatccaggagcttgaggagcagctggaggaggaggagagcgcccggcag
aagctgcagctggagaaggtgaccaccgaggcgaagctgaaaaagctggaggaggagcag
atcatcctggaggaccagaactgcaagctggccaaggaaaagaaactgctggaagacaga
atagctgagttcaccaccaacctcacagaagaggaggagaaatctaagagcctcgccaag
ctcaagaacaagcatgaggcaatgatcactgacttggaagagcgcctccgcagggaggag
aagcagcgacaggagctggagaagacccgccggaagctggagggagactccacagacctc
agcgaccagatcgccgagctccaggcccagatcgcggagctcaagatgcagctggccaag
aaagaggaggagctccaggccgccctggccagagtggaagaggaagctgcccagaagaac
atggccctcaagaagatccgggagctggaatctcagatctctgaactccaggaagacctg
gagtctgagcgtgcttccaggaataaagctgagaagcagaaacgggaccttggggaagag
ctagaggctctgaaaacagagttggaggacacgctggattccacagctgcccagcaggag
ctcaggtcaaaacgtgagcaggaggtgaacatcctgaagaagaccctggaggaggaggcc
aagacccacgaggcccagatccaggagatgaggcagaagcactcacaggccgtggaggag
ctggcggagcagctggagcagacgaagcgggtgaaagcaaacctcgagaaggcaaagcag
actctggagaacgagcggggggagctggccaacgaggtgaaggtgctgctgcagggcaaa
ggggactcggagcacaagcgcaagaaagtggaggcgcagctgcaggagctgcaggtcaag
ttcaacgagggagagcgcgtgcgcacagagctggccgacaaggtcaccaagctgcaggtg
gagctggacaacgtgaccgggcttctcagccagtccgacagcaagtccagcaagctcacc
aaggacttctccgcgctggagtcccagctgcaggacactcaggagctgctgcaggaggag
aaccggcagaagctgagcctgagcaccaagctcaagcaggtggaggacgagaagaattcc
ttccgggagcagctggaggaggaggaggaggccaagcacaacctggagaagcagatcgcc
accctccatgcccaggtggccgacatgaaaaagaagatggaggacagtgtggggtgcctg
gaaactgctgaggaggtgaagaggaagctccagaaggacctggagggcctgagccagcgg
cacgaggagaaggtggccgcctacgacaagctggagaagaccaagacgcggctgcagcag
gagctggacgacctgctggtggacctggaccaccagcgccagagcgcgtgcaacctggag
aagaagcagaagaagtttgaccagctcctggcggaggagaagaccatctctgccaagtat
gcagaggagcgcgaccgggctgaggcggaggcccgagagaaggagaccaaggctctgtcg
ctggcccgggccctggaggaagccatggagcagaaggcggagctggagcggctcaacaag
cagttccgcacggagatggaggaccttatgagctccaaggatgatgtgggcaagagtgtc
cacgagctggagaagtccaagcgggccctagagcagcaggtggaggagatgaagacgcag
ctggaagagctggaggacgagctgcaggccaccgaagatgccaagctgcggttggaggtc
aacctgcaggccatgaaggcccagttcgagcgggacctgcagggccgggacgagcagagc
gaggagaagaagaagcagctggtcagacaggtgcgggagatggaggcagagctggaggac
gagaggaagcagcgctcgatggcagtggccgcccggaagaagctggagatggacctgaag
gacctggaggcgcacatcgactcggccaacaagaaccgggacgaagccatcaaacagctg
cggaagctgcaggcccagatgaaggactgcatgcgcgagctggatgacacccgcgcctct
cgtgaggagatcctggcccaggccaaagagaacgagaagaagctgaagagcatggaggcc
gagatgatccagttgcaggaggaactggcagccgcggagcgtgccaagcgccaggcccag
caggagcgggatgagctggctgacgagatcgccaacagcagcggcaaaggagccctggcg
ttagaggagaagcggcgtctggaggcccgcatcgcccagctggaggaggagctggaggag
gagcagggcaacacggagctgatcaacgaccggctgaagaaggccaacctgcagatcgac
cagatcaacaccgacctgaacctggagcgcagccacgcccagaagaacgagaatgctcgg
cagcagctggaacgccagaacaaggagcttaaggtcaagctgcaggagatggagggcact
gtcaagtccaagtacaaggcctccatcaccgccctcgaggccaagattgcacagctggag
gagcagctggacaacgagaccaaggagcgccaggcagcctgcaaacaggtgcgtcggacc
gagaagaagctgaaggatgtgctgctgcaggtggatgacgagcggaggaacgccgagcag
tacaaggaccaggccgacaaggcatctacccgcctgaagcagctcaagcggcagctggag
gaggccgaagaggaggcccagcgggccaacgcctcccgccggaaactgcagcgcgagctg
gaggacgccactgagacggccgatgccatgaaccgcgaagtcagctccctaaagaacaag
ctcaggcgcggggacctgccgtttgtcgtgccccgccgaatggcccggaaaggcgccggg
gatggctccgacgaagaggtagatggcaaagcggatggggctgaggccaaacctgccgaa
taa
Homo sapiens (human): 4628
Help
Entry
4628 CDS
T01001
Symbol
MYH10, NMMHC-IIB, NMMHCB
Name
(RefSeq) myosin heavy chain 10
KO
K10352
myosin heavy chain 9/10/11/14
Organism
hsa
Homo sapiens (human)
Pathway
hsa04270
Vascular smooth muscle contraction
hsa04530
Tight junction
hsa04810
Regulation of actin cytoskeleton
hsa04814
Motor proteins
hsa04820
Cytoskeleton in muscle cells
hsa05130
Pathogenic Escherichia coli infection
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09144 Cellular community - eukaryotes
04530 Tight junction
4628 (MYH10)
09142 Cell motility
04814 Motor proteins
4628 (MYH10)
04820 Cytoskeleton in muscle cells
4628 (MYH10)
04810 Regulation of actin cytoskeleton
4628 (MYH10)
09150 Organismal Systems
09153 Circulatory system
04270 Vascular smooth muscle contraction
4628 (MYH10)
09160 Human Diseases
09171 Infectious disease: bacterial
05130 Pathogenic Escherichia coli infection
4628 (MYH10)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
hsa04812
]
4628 (MYH10)
04147 Exosome [BR:
hsa04147
]
4628 (MYH10)
Cytoskeleton proteins [BR:
hsa04812
]
Eukaryotic cytoskeleton proteins
Actin filaments / Microfilaments
Actin-binding proteins
Myosins
4628 (MYH10)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of bladder cancer cells
4628 (MYH10)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Myosin_tail_1
Myosin_head
Myosin_N
ADIP
IQ
ERM_helical
CC2-LZ
AAA_22
Motif
Other DBs
NCBI-GeneID:
4628
NCBI-ProteinID:
NP_005955
OMIM:
160776
HGNC:
7568
Ensembl:
ENSG00000133026
UniProt:
P35580
Structure
PDB
LinkDB
All DBs
Position
17:complement(8474212..8630725)
Genome browser
AA seq
1976 aa
AA seq
DB search
MAQRTGLEDPERYLFVDRAVIYNPATQADWTAKKLVWIPSERHGFEAASIKEERGDEVMV
ELAENGKKAMVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGL
FCVVINPYKNLPIYSENIIEMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGES
GAGKTENTKKVIQYLAHVASSHKGRKDHNIPGELERQLLQANPILESFGNAKTVKNDNSS
RFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLL
LEGFNNYRFLSNGYIPIPGQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNIS
FKKERNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFA
VEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTN
EKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECW
FPKATDKTFVEKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLN
DNVATLLHQSSDRFVAELWKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKES
LTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIV
FQEFRQRYEILTPNAIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEE
ERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTK
VKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAET
ELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLD
EEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEE
KAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDE
LKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQ
KRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQR
HATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQ
VQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDT
QELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKV
DDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQR
QVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKE
EFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATED
AKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKK
KMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEK
KLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQ
LEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAK
LQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVED
ERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSRE
VSTLKNRLRRGGPISFSSSRSGRRQLHLEGASLELSDDDTESKTSDVNETQPPQSE
NT seq
5931 nt
NT seq
+upstream
nt +downstream
nt
atggcgcagagaactggactcgaggatccagagaggtatctctttgtggacagggctgtc
atctacaaccctgccactcaagctgattggacagctaaaaagctagtgtggattccatca
gaacgccatggttttgaggcagctagtatcaaagaagaacggggagatgaagttatggtg
gagttggcagagaatggaaagaaagcaatggtcaacaaagatgatattcagaagatgaac
ccacctaagttttccaaggtggaggatatggcagaattgacatgcttgaatgaagcttcc
gttttacataatctgaaggatcgctactattcaggactaatctatacttattctggactc
ttctgtgtagttataaacccttacaagaatcttccaatttactctgagaatattattgaa
atgtacagagggaagaagcgtcatgagatgcctccacacatctatgctatatctgaatct
gcttacagatgcatgcttcaagatcgtgaggaccagtcaattctttgcacgggtgagtca
ggtgctgggaagacagaaaatacaaagaaagttattcagtaccttgcccatgttgcttct
tcacataaaggaagaaaggaccataatattcctggggaacttgaacggcagcttttgcaa
gcaaatccaattctggaatcatttggaaatgcgaagactgtgaaaaatgataactcatct
cgttttggcaaatttattcggatcaactttgatgtaactggctatatcgttggggccaac
attgaaacataccttctggaaaagtctcgtgctgttcgtcaagcaaaagatgaacgtact
tttcatatcttttaccagttgttatctggagcaggagaacacctaaagtctgatttgctt
cttgaaggatttaataactacaggtttctctccaatggctatattcctattccgggacag
caagacaaagataatttccaggagaccatggaagcaatgcacataatgggcttctcccat
gaagagattctgtcaatgcttaaagtagtatcttcagtgctacagtttggaaatatttct
ttcaaaaaggagagaaatactgatcaagcttccatgccagaaaatacagttgcgcagaag
ctctgccatcttcttgggatgaatgtgatggagtttactcgggccatcctgactccccgg
atcaaggtcggccgagactatgtgcaaaaagcccagaccaaagaacaggcagattttgca
gtagaagcattggcaaaagctacctatgagcggctctttcgctggctcgttcatcgcatc
aataaagctctggataggaccaaacgtcagggagcatctttcattggaatcctggatatt
gctggatttgaaatttttgagctgaactcctttgaacaactttgcatcaactacaccaat
gagaagctgcagcagctgttcaaccacaccatgtttatcctagaacaagaggaataccag
cgcgaaggcatcgagtggaacttcatcgatttcgggctggatctgcagccatgcatcgac
ctaatagagagacctgcgaaccctcctggtgtactggcccttttggatgaagaatgctgg
ttccctaaagccacagataaaacctttgttgaaaaactggttcaagagcaaggttcccac
tccaagtttcagaaacctcgacaattaaaagacaaagctgatttttgcattatacattat
gcagggaaggtggactataaggcagatgagtggctgatgaagaatatggaccccctgaat
gacaacgtggccacccttttgcaccagtcatcagacagatttgtggcagagctttggaaa
gatgtggaccgtatcgtgggtctggatcaagtcactggtatgactgagacagcttttggc
tccgcatataaaaccaagaagggcatgtttcgtaccgttgggcaactctacaaagaatct
ctcaccaagctgatggcaactctccgaaacaccaaccctaactttgttcgttgtatcatt
ccaaatcacgagaagagggctggaaaattggatccacacctagtcctagatcagcttcgc
tgtaacggtgtcctggaagggatccgaatctgtcgccagggcttccctaaccgaatagtt
ttccaggaattcagacagagatatgagatcctaactccaaatgctattcctaaaggtttt
atggatggtaaacaggcctgtgaacgaatgatccgggctttagaattggacccaaacttg
tacagaattggacagagcaagatatttttcagagctggagttctggcacacttagaggaa
gaaagagatttaaaaatcaccgatatcattatcttcttccaggccgtttgcagaggttac
ctggccagaaaggcctttgccaagaagcagcagcaactaagtgccttaaaggtcttgcag
cggaactgtgccgcgtacctgaaattacggcactggcagtggtggcgagtcttcacaaag
gtgaagccgcttctacaagtgactcgccaggaggaagaacttcaggccaaagatgaagag
ctgttgaaggtgaaggagaagcagacgaaggtggaaggagagctggaggagatggagcgg
aagcaccagcagcttttagaagagaagaatatccttgcagaacaactacaagcagagact
gagctctttgctgaagcagaagagatgagggcaagacttgctgctaaaaagcaggaatta
gaagagattctacatgacttggagtctagggttgaagaagaagaagaaagaaaccaaatc
ctccaaaatgaaaagaaaaaaatgcaagcacatattcaggacctggaagaacagctagac
gaggaggaaggggctcggcaaaagctgcagctggaaaaggtgacagcagaggccaagatc
aagaagatggaagaggagattctgcttctcgaggaccaaaattccaagttcatcaaagaa
aagaaactcatggaagatcgcattgctgagtgttcctctcagctggctgaagaggaagaa
aaggcgaaaaacttggccaaaatcaggaataagcaagaagtgatgatctcagatttagaa
gaacgcttaaagaaggaagaaaagactcgtcaggaactggaaaaggccaaaagaaaactc
gacggggagacgaccgacctgcaggaccagatcgcagagctgcaggcgcagattgatgag
ctcaagctgcagctggccaagaaggaggaggagctgcagggcgcactggccagaggtgat
gatgaaacactccataagaacaatgcccttaaagttgtgcgagagctacaagcccaaatt
gctgaacttcaggaagactttgaatccgagaaggcttcacggaacaaggccgaaaagcag
aaaagggacttgagtgaggaactggaagctctgaaaacagagctggaggacacgctggac
accacggcagcccagcaggaactacgtacaaaacgtgaacaagaagtggcagagctgaag
aaagctcttgaggaggaaactaagaaccatgaagctcaaatccaggacatgagacaaaga
cacgcaacagccctggaggagctctcagagcagctggaacaggccaagcggttcaaagca
aatctagagaagaacaagcagggcctggagacagataacaaggagctggcgtgtgaggtg
aaggtcctgcagcaggtcaaggctgagtctgagcacaagaggaagaagctcgacgcgcag
gtccaggagctccatgccaaggtctctgaaggcgacaggctcagggtggagctggcggag
aaagcaagtaagctgcagaatgagctagataatgtctccacccttctggaagaagcagag
aagaagggtattaaatttgctaaggatgcagctagtcttgagtctcaactacaggataca
caggagcttcttcaggaggagacacgccagaaactaaacctgagcagtcggatccggcag
ctggaagaggagaagaacagtcttcaggagcagcaggaggaggaggaggaggccaggaag
aacctggagaagcaagtgctggccctgcagtcccagttggctgataccaagaagaaagta
gatgacgacctgggaacaattgaaagtctggaagaagccaagaagaagcttctgaaggac
gcggaggccctgagccagcgcctggaggagaaggcactggcgtatgacaaactggagaag
accaagaaccgcctgcagcaggagctggacgacctcacggtggacctggaccaccagcgc
caggtcgcctccaacttggagaagaagcagaagaagtttgaccagctgttagcagaagag
aagagcatctctgctcgctatgccgaagagcgggaccgggccgaagccgaggccagagag
aaagaaaccaaagccctgtcactggcccgggccctcgaggaagccctggaggccaaggag
gagtttgagaggcagaacaagcagctccgagcagacatggaagacctcatgagctccaaa
gatgatgtgggaaaaaacgttcacgaacttgaaaaatccaaacgggccctagagcagcag
gtggaggaaatgaggacccagctggaggagctggaagacgaactccaggccacggaagat
gccaagcttcgtctggaggtcaacatgcaggccatgaaggcgcagttcgagagagacctg
caaaccagggatgagcagaatgaagagaagaagcggctgctgatcaaacaggtgcgggag
ctcgaggcggagctggaggatgagaggaaacagcgggcgcttgctgtagcttcaaagaaa
aagatggagatagacctgaaggacctcgaagcccaaatcgaggctgcgaacaaagctcgg
gatgaggtgattaagcagctccgcaagctccaggctcagatgaaggattaccaacgtgaa
ttagaagaagctcgtgcatccagagatgagatttttgctcaatccaaagagagtgaaaag
aaattgaagagtctggaagcagaaatccttcaattgcaggaggaacttgcctcatctgag
cgagcccgccgacacgccgagcaggagagagatgagctggcggacgagatcaccaacagc
gcctctggcaagtccgcgctgctggatgagaagcggcgtctggaagctcggatcgcacag
ctggaggaggagctggaagaggagcagagcaacatggagctgctcaacgaccgcttccgc
aagaccactctacaggtggacacactgaacgccgagctagcagccgagcgcagcgccgcc
cagaagagtgacaatgcacgccagcaactggagcggcagaacaaggagctgaaggccaag
ctgcaggaactcgagggtgctgtcaagtctaagttcaaggccaccatctcagccctggag
gccaagattgggcagctggaggagcagcttgagcaggaagccaaggaacgagcagccgcc
aacaaattagtccgtcgcactgagaagaagctgaaagaaatcttcatgcaggttgaggat
gagcgtcgacacgcggaccagtataaagagcagatggagaaggccaacgctcggatgaag
cagcttaaacgccagctggaggaagcagaagaagaagcgacgcgtgccaacgcatctcgg
cgtaaactccagcgggaactggatgatgccaccgaggccaacgagggcctgagccgcgag
gtcagcaccctgaagaaccggctgaggcggggtggccccatcagcttctcttccagccga
tctggccggcgccagctgcaccttgaaggagcttccctggagctctccgacgatgacaca
gaaagtaagaccagtgatgtcaacgagacgcagccaccccagtcagagtaa
Homo sapiens (human): 4629
Help
Entry
4629 CDS
T01001
Symbol
MYH11, AAT4, FAA4, SMHC, SMMHC, SMMS-1, VSCM2
Name
(RefSeq) myosin heavy chain 11
KO
K10352
myosin heavy chain 9/10/11/14
Organism
hsa
Homo sapiens (human)
Pathway
hsa04270
Vascular smooth muscle contraction
hsa04530
Tight junction
hsa04810
Regulation of actin cytoskeleton
hsa04814
Motor proteins
hsa04820
Cytoskeleton in muscle cells
hsa05130
Pathogenic Escherichia coli infection
Network
nt06539
Cytoskeleton in muscle cells
Element
N01817
Myosin thick filament
N01818
Actin thin filament, muscle contraction
Disease
H00801
Familial thoracic aortic aneurysm and dissection
H01869
Megacystis microcolon intestinal hypoperistalsis syndrome
H02553
Visceral myopathy
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09144 Cellular community - eukaryotes
04530 Tight junction
4629 (MYH11)
09142 Cell motility
04814 Motor proteins
4629 (MYH11)
04820 Cytoskeleton in muscle cells
4629 (MYH11)
04810 Regulation of actin cytoskeleton
4629 (MYH11)
09150 Organismal Systems
09153 Circulatory system
04270 Vascular smooth muscle contraction
4629 (MYH11)
09160 Human Diseases
09171 Infectious disease: bacterial
05130 Pathogenic Escherichia coli infection
4629 (MYH11)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
hsa04812
]
4629 (MYH11)
04147 Exosome [BR:
hsa04147
]
4629 (MYH11)
Cytoskeleton proteins [BR:
hsa04812
]
Eukaryotic cytoskeleton proteins
Actin filaments / Microfilaments
Actin-binding proteins
Myosins
4629 (MYH11)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of bladder cancer cells
4629 (MYH11)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Myosin_tail_1
Myosin_head
Myosin_N
ERM_helical
CC2-LZ
IQ
ATG16
ADIP
AAA_22
Motif
Other DBs
NCBI-GeneID:
4629
NCBI-ProteinID:
NP_002465
OMIM:
160745
HGNC:
7569
Ensembl:
ENSG00000133392
UniProt:
P35749
A0A024QZJ4
LinkDB
All DBs
Position
16:complement(15703135..15857028)
Genome browser
AA seq
1972 aa
AA seq
DB search
MAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVV
ELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGL
FCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGES
GAGKTENTKKVIQYLAVVASSHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSS
RFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLL
LEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIV
FKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFA
VEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTN
EKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECW
FPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLN
DNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQ
LGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIV
FQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEE
ERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTK
VKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET
ELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE
EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEE
KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAE
LKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQ
KRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQK
HAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQ
VQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDT
QELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL
QDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR
QLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE
ELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATED
AKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK
KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK
KAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ
LEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSK
LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVED
ERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGRE
VNALKSKLRRGNETSFVPSRRSGGRRVIENADGSEEETDTRDADFNGTKASE
NT seq
5919 nt
NT seq
+upstream
nt +downstream
nt
atggcgcagaagggccaactcagtgacgatgagaagttcctctttgtggacaaaaacttc
atcaacagcccagtggcccaggctgactgggccgccaagagactcgtctgggtcccctcg
gagaagcagggcttcgaggcagccagcattaaggaggagaagggggatgaggtggttgtg
gagctggtggagaatggcaagaaggtcacggttgggaaagatgacatccagaagatgaac
ccacccaagttctccaaggtggaggacatggcggagctgacgtgcctcaacgaagcctcc
gtgctacacaacctgagggagcggtacttctcagggctaatatatacgtactctggcctc
ttctgcgtggtggtcaacccctataaacacctgcccatctactcggagaagatcgtcgac
atgtacaagggcaagaagaggcacgagatgccgcctcacatctacgccatcgcagacacg
gcctaccggagcatgcttcaagatcgggaggaccagtccattctatgcacaggcgagtct
ggagccgggaaaaccgaaaacaccaagaaggtcattcagtacctggccgtggtggcctcc
tcccacaagggcaagaaagacacaagtatcacgggagagctggaaaagcagcttctacaa
gcaaacccgattctggaggctttcggcaacgccaaaacagtgaagaacgacaactcctca
cgattcggcaaattcatccgcatcaacttcgacgtcacgggttacatcgtgggagccaac
attgagacctatctgctagaaaaatcacgggcaattcgccaagccagagacgagaggaca
ttccacatcttttactacatgattgctggagccaaggagaagatgagaagtgacttgctt
ttggagggcttcaacaactacaccttcctctccaatggctttgtgcccatcccagcagcc
caggatgatgagatgttccaggaaaccgtggaggccatggcaatcatgggtttcagcgag
gaggagcagctatccatattgaaggtggtatcatcggtcctgcagcttggaaatatcgtc
ttcaagaaggaaagaaacacagaccaggcgtccatgccagataacacagctgctcagaaa
gtttgccacctcatgggaattaatgtgacagatttcaccagatccatcctcactcctcgt
atcaaggttgggcgagatgtggtacagaaagctcagacaaaagaacaggctgactttgct
gtagaggctttggccaaggcaacatatgagcgccttttccgctggatactcacccgcgtg
aacaaagccctggacaagacccatcggcaaggggcttccttcctggggatcctggatata
gctggatttgagatctttgaggtgaactccttcgagcagctgtgcatcaactacaccaac
gagaagctgcagcagctcttcaaccacaccatgttcatcctggagcaggaggagtaccag
cgcgagggcatcgagtggaacttcatcgactttgggctggacctacagccctgcatcgag
ctcatcgagcgaccgaacaaccctccaggtgtgctggccctgctggacgaggaatgctgg
ttccccaaagccacggacaagtctttcgtggagaagctgtgcacggagcagggcagccac
cccaagttccagaagcccaagcagctcaaggacaagactgagttctccatcatccattat
gctgggaaggtggactataatgcgagtgcctggctgaccaagaatatggacccgctgaat
gacaacgtgacttccctgctcaatgcctcctccgacaagtttgtggccgacctgtggaag
gacgtggaccgcatcgtgggcctggaccagatggccaagatgacggagagctcgctgccc
agcgcctccaagaccaagaagggcatgttccgcacagtggggcagctgtacaaggagcag
ctgggcaagctgatgaccacgctacgcaacaccacgcccaacttcgtgcgctgcatcatc
cccaaccacgagaagaggtccggcaagctggatgcgttcctggtgctggagcagctgcgg
tgcaatggggtgctggaaggcattcgcatctgccggcagggcttccccaaccggatcgtc
ttccaggagttccgccaacgctacgagatcctggcggcgaatgccatccccaaaggcttc
atggacgggaagcaggcctgcattctcatgatcaaagccctggaacttgaccccaactta
tacaggatagggcagagcaaaatcttcttccgaactggcgtcctggcccacctagaggag
gagcgagatttgaagatcaccgatgtcatcatggccttccaggcgatgtgtcgtggctac
ttggccagaaaggcttttgccaagaggcagcagcagctgaccgccatgaaggtgattcag
aggaactgcgccgcctacctcaagctgcggaactggcagtggtggaggcttttcaccaaa
gtgaagccactgctgcaggtgacacggcaggaggaggagatgcaggccaaggaggatgaa
ctgcagaagaccaaggagcggcagcagaaggcagagaatgagcttaaggagctggaacag
aagcactcgcagctgaccgaggagaagaacctgctacaggaacagctgcaggcagagaca
gagctgtatgcagaggctgaggagatgcgggtgcggctggcggccaagaagcaggagctg
gaggagatactgcatgagatggaggcccgcctggaggaggaggaagacaggggccagcag
ctacaggctgaaaggaagaagatggcccagcagatgctggaccttgaagaacagctggag
gaggaggaagctgccaggcagaagctgcaacttgagaaggtcacggctgaggccaagatc
aagaaactggaggatgagatcctggtcatggatgatcagaacaataaactatcaaaagaa
cgaaaactccttgaggagaggattagtgacttaacgacaaatcttgcagaagaggaagaa
aaggccaagaatcttaccaagctgaaaaacaagcatgaatctatgatttcagaactggaa
gtgcggctaaagaaggaagagaagagccgacaggagctggagaagctgaaacggaagctg
gagggtgatgccagcgacttccacgagcagatcgctgacctccaggcgcagatcgcagag
ctcaagatgcagctggccaagaaggaggaggagctgcaggcggccctggccaggcttgac
gatgaaatcgctcagaagaacaatgccctgaagaagatccgggagctggagggccacatc
tcagacctccaggaggacctggactcagagcgggccgccaggaacaaggctgaaaagcag
aagcgagacctcggcgaggagctggaggccctaaagacagagctggaagacacactggac
agcacagccactcagcaggagctcagggccaagagggagcaggaggtgacggtgctgaag
aaggccctggatgaagagacgcggtcccatgaggctcaggtccaggagatgaggcagaaa
cacgcacaggcggtggaggagctcacagagcagcttgagcagttcaagagggccaaggcg
aacctagacaagaataagcagacgctggagaaagagaacgcagacctggccggggagctg
cgggtcctgggccaggccaagcaggaggtggaacataagaagaagaagctggaggcgcag
gtgcaggagctgcagtccaagtgcagcgatggggagcgggcccgggcggagctcaatgac
aaagtccacaagctgcagaatgaagttgagagcgtcacagggatgcttaacgaggccgag
gggaaggccattaagctggccaaggacgtggcgtccctcagttcccagctccaggacacc
caggagctgcttcaagaagaaacccggcagaagctcaacgtgtctacgaagctgcgccag
ctggaggaggagcggaacagcctgcaagaccagctggacgaggagatggaggccaagcag
aacctggagcgccacatctccactctcaacatccagctctccgactcgaagaagaagctg
caggactttgccagcaccgtggaagctctggaagaggggaagaagaggttccagaaggag
atcgagaacctcacccagcagtacgaggagaaggcggccgcttatgataaactggaaaag
accaagaacaggcttcagcaggagctggacgacctggttgttgatttggacaaccagcgg
caactcgtgtccaacctggaaaagaagcagaggaaatttgatcagttgttagccgaggag
aaaaacatctcttccaaatacgcggatgagagggacagagctgaggcagaagccagggag
aaggaaaccaaggccctgtccctggctcgggcccttgaagaggccttggaagccaaagag
gaactcgagcggaccaacaaaatgctcaaagccgaaatggaagacctggtcagctccaag
gatgacgtgggcaagaacgtccatgagctggagaagtccaagcgggccctggagacccag
atggaggagatgaagacgcagctggaagagctggaggacgagctgcaagccacggaggac
gccaaactgcggctggaagtcaacatgcaggcgctcaagggccagttcgaaagggatctc
caagcccgggacgagcagaatgaggagaagaggaggcaactgcagagacagcttcacgag
tatgagacggaactggaagacgagcgaaagcaacgtgccctggcagctgcagcaaagaag
aagctggaaggggacctgaaagacctggagcttcaggccgactctgccatcaaggggagg
gaggaagccatcaagcagctacgcaaactgcaggctcagatgaaggactttcaaagagag
ctggaagatgcccgtgcctccagagatgagatctttgccacagccaaagagaatgagaag
aaagccaagagcttggaagcagacctcatgcagctacaagaggacctcgccgccgctgag
agggctcgcaaacaagcggacctcgagaaggaggaactggcagaggagctggccagtagc
ctgtcgggaaggaacgcactccaggacgagaagcgccgcctggaggcccggatcgcccag
ctggaggaggagctggaggaggagcagggcaacatggaggccatgagcgaccgggtccgc
aaagccacacagcaggccgagcagctcagcaacgagctggccacagagcgcagcacggcc
cagaagaatgagagtgcccggcagcagctcgagcggcagaacaaggagctccggagcaag
ctccacgagatggagggggccgtcaagtccaagttcaagtccaccatcgcggcgctggag
gccaagattgcacagctggaggagcaggtcgagcaggaggccagagagaaacaggcggcc
accaagtcgctgaagcagaaagacaagaagctgaaggaaatcttgctgcaggtggaggac
gagcgcaagatggccgagcagtacaaggagcaggcagagaaaggcaatgccagggtcaag
cagctcaagaggcagctggaggaggcagaggaggagtcccagcgcatcaacgccaaccgc
aggaagctgcagcgggagctggatgaggccacggagagcaacgaggccatgggccgcgag
gtgaacgcactcaagagcaagctcaggcgaggaaacgagacctctttcgttccttctaga
aggtctggaggacgtagagttattgaaaatgcagatggttctgaggaggaaacggacact
cgagacgcagacttcaatggaaccaaggccagtgaataa
Homo sapiens (human): 79784
Help
Entry
79784 CDS
T01001
Symbol
MYH14, DFNA4, DFNA4A, FP17425, MHC16, MYH17, NMHC_II-C, NMHC-II-C, PNMHH, myosin
Name
(RefSeq) myosin heavy chain 14
KO
K10352
myosin heavy chain 9/10/11/14
Organism
hsa
Homo sapiens (human)
Pathway
hsa04270
Vascular smooth muscle contraction
hsa04530
Tight junction
hsa04810
Regulation of actin cytoskeleton
hsa04814
Motor proteins
hsa04820
Cytoskeleton in muscle cells
hsa05130
Pathogenic Escherichia coli infection
Disease
H00604
Deafness, autosomal dominant
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09144 Cellular community - eukaryotes
04530 Tight junction
79784 (MYH14)
09142 Cell motility
04814 Motor proteins
79784 (MYH14)
04820 Cytoskeleton in muscle cells
79784 (MYH14)
04810 Regulation of actin cytoskeleton
79784 (MYH14)
09150 Organismal Systems
09153 Circulatory system
04270 Vascular smooth muscle contraction
79784 (MYH14)
09160 Human Diseases
09171 Infectious disease: bacterial
05130 Pathogenic Escherichia coli infection
79784 (MYH14)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
hsa04812
]
79784 (MYH14)
04147 Exosome [BR:
hsa04147
]
79784 (MYH14)
Cytoskeleton proteins [BR:
hsa04812
]
Eukaryotic cytoskeleton proteins
Actin filaments / Microfilaments
Actin-binding proteins
Myosins
79784 (MYH14)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of bladder cancer cells
79784 (MYH14)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Myosin_tail_1
Myosin_head
Myosin_N
ADIP
IQ
AAA_22
VBS
Motif
Other DBs
NCBI-GeneID:
79784
NCBI-ProteinID:
NP_079005
OMIM:
608568
HGNC:
23212
Ensembl:
ENSG00000105357
UniProt:
Q7Z406
Structure
PDB
LinkDB
All DBs
Position
19:50203622..50310540
Genome browser
AA seq
1995 aa
AA seq
DB search
MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS
ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS
VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG
AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPGELERQLLQ
ANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECS
FHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESLRVLGFSHE
EIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRI
KVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIA
GFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDL
IERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQADFSVLHYA
GKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIVGLEQVSSLGDGPPGG
RPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNG
VLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRV
GQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNC
AAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVA
QLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQT
EKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKL
LEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGE
SSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEA
QEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTL
EEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSL
QTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKT
IRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAG
RELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRR
RLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREA
RALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAAND
LRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEV
ERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEE
TRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLS
KAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKA
ESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKL
VRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRL
QRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGS
GPSPEPEGSPPAHPQ
NT seq
5988 nt
NT seq
+upstream
nt +downstream
nt
atggcagccgtgaccatgtcggtgcccgggcggaaggcgccccccaggccgggcccagtg
cccgaggcggcccagccgttcctgttcacgccccgcgggcccagcgcgggtggcgggcct
ggctcgggcacctccccgcaggtggagtggacggcccggcgtctcgtgtgggtgccttcg
gagcttcacgggttcgaggcggcggcgctgcgggacgaaggcgaggaggaggcggaggtg
gagctggcggagagcgggaggcggctgcgactgccgcgggaccagatccagcgcatgaac
ccgcccaagttcagcaaggccgaggacatggccgagctgacctgcctcaacgaggcctcg
gtcctgcacaacctccgggagcggtactactccggcctcatctacacgtactccggcctt
ttctgtgtggtcatcaacccgtacaagcagcttcccatctacacagaagccattgtggag
atgtaccggggcaagaagcgccacgaggtgccaccccacgtgtacgcagtgaccgagggg
gcctatcggagcatgctgcaggatcgtgaggaccagtccattctctgcactggagagtct
ggagctgggaagacggaaaacaccaagaaggtcatccagtacctcgcccacgtggcgtcg
tctccaaagggcaggaaggagccgggtgtccccggtgagctggagcggcagctgcttcag
gccaaccccatcctagaggcctttggcaatgccaagacagtgaagaatgacaactcctcc
cgattcggcaaattcatccgcatcaactttgatgttgccgggtacatcgtgggcgccaac
attgagacctacctgctggagaagtcgcgggccatccgccaggccaaggacgagtgcagc
ttccacatcttctaccagctgctggggggcgctggagagcagctcaaagccgacctcctc
ctcgagccctgctcccactaccggttcctgaccaacgggccgtcatcctctcccggccag
gagcgggaactcttccaggagacgctggagtcgctgcgggtcctgggattcagccacgag
gaaatcatctccatgctgcggatggtctcagcagttctccagtttggcaacattgccttg
aagagagaacggaacaccgatcaagccaccatgcctgacaacacagctgcacagaagctc
tgccgcctcttgggactgggggtgacggatttctcccgagccttgctcacccctcgcatc
aaagttggccgagactatgtgcagaaagcccagactaaggaacaggctgacttcgcgctg
gaggccctggccaaggccacctacgagcgcctcttccgctggctggttctgcgcctcaac
cgggccttggaccgcagcccccgccaaggcgcctccttcctgggcatcctggacatcgcg
ggctttgagatcttccagctgaactccttcgagcagctctgcatcaactacaccaacgag
aagctgcagcagctcttcaaccacaccatgttcgtgctggagcaggaggagtaccagcgt
gagggcatcccctggaccttcctcgactttggcctcgacctgcagccctgcatcgacctc
atcgagcggccggccaacccccctggactcctggccctgctggatgaggagtgctggttc
ccgaaggccacagacaagtcgtttgtggagaaggtagcccaggagcagggcggccacccc
aagttccagcggccgaggcacctgcgggatcaggccgacttcagtgttctccactacgcg
ggcaaggtcgactacaaggccaacgagtggctgatgaaaaacatggaccctctgaatgac
aacgtcgcagccttgctccaccagagcacagaccggctgacggcagagatctggaaagac
gtggagggcatcgtggggctggaacaggtgagcagcctgggcgacggcccaccaggtggc
cgcccccgtcggggtatgttccggacagtgggacagctctacaaggagtccctgagccgc
ctcatggccacactcagcaacaccaaccccagttttgtccgctgcattgtccccaaccac
gagaagagggccgggaagctggagccacggctggtgctggaccagcttcgctgcaacggg
gtcctggagggcatccgcatctgtcgccagggcttccccaaccgcatcctcttccaggag
ttccggcagcgatacgagatcctgacacccaatgccatccccaagggcttcatggatggg
aagcaggcctgtgaaaagatgatccaggcgctggaactggaccccaacctctaccgcgtg
ggacagagcaagatcttcttccgggctggggtcctggcccagctggaagaggagcgagac
ctgaaggtcaccgacatcatcgtctccttccaggcagctgcccggggatacctggctcgc
agggccttccagaagcgccagcagcagcagagcgccctgagggtgatgcagcggaactgc
gcggcctacctcaagctgagacactggcagtggtggcggctgtttaccaaggtgaagcca
ctgctgcaggtgacgcggcaggatgaggtgctgcaggcacgggcccaggagctgcagaaa
gtgcaggagctacagcagcagagcgcccgcgaagttggggagctccagggccgagtggca
cagctggaagaggagcgcgcccgcctggcagagcaattgcgagcagaggcagaactgtgt
gcagaggccgaggagacgcgggggaggctggcagcccgcaagcaggagctggagctggtg
gtgtcagagctggaggctcgcgtgggcgaggaggaggagtgcagccgtcaaatgcaaacc
gagaagaagaggctgcagcagcacatacaggagctagaggcccaccttgaggctgaggag
ggtgcgcggcagaagctgcagctggagaaggtgacgacagaggcaaaaatgaagaaattt
gaagaggacctgctgctcctggaagaccagaattccaagctgagcaaggagcggaagctg
ctggaagatcgtctggccgagttctcatcccaggcagctgaggaggaggagaaggtcaag
agcctcaataagctacggctcaaatatgaggccacaatcgcagacatggaggaccgccta
cggaaggaggagaagggtcgccaggagctggagaagctgaagcggaggctggatggggag
agctcagagctgcaggagcagatggtggagcagcaacagcgggcagaggagctgcgggcc
cagctgggccggaaggaggaggagctgcaggctgccctggccagggcagaagacgagggt
ggggcccgggcccagctgctgaaatccctgcgggaggctcaagcagccctggccgaggcc
caggaggacctggagtctgagcgtgtggccaggaccaaggcggagaagcagcgccgggac
ctgggcgaggagctggaggcgctgcggggcgagctggaggacacgctggactccaccaac
gcacagcaggagctccggtccaagagggaacaggaggtgacggagctgaagaagactctg
gaggaggagactcgcatccacgaggcggcagtgcaggagctgaggcagcgccacggccag
gccctgggggagctggcggagcagctggagcaggcccggaggggcaaaggtgcatgggag
aagacccggctggccctggaggccgaggtgtccgagctgcgggcagaactgagcagcctg
cagactgcacgtcaggagggtgagcagcggaggcgccgcctggagttacagctgcaggag
gtgcagggccgggctggtgatggggagagggcacgagcggaggctgctgagaagctgcag
cgagcccaggctgaactggagaatgtgtctggggcgctgaacgaggctgagtccaaaacc
atccgtcttagcaaggagctgagcagcacagaagcccagctgcacgatgcccaggagctg
ctgcaggaggagaccagggcgaaattggccttggggtcccgggtgcgagccatggaggct
gaggcagccgggctgcgtgagcagctggaggaggaggcagctgccagggaacgggcgggc
cgtgaactgcagactgcccaggcccagctttccgagtggcggcggcgccaggaggaggag
gcaggggcactggaggcaggggaggaggcacggcgccgggcagcccgggaggccgaggcc
ctgacccagcgcctggcagaaaagacagagaccgtggatcggctggagcggggccgccgc
cggctgcagcaggagctggacgacgccaccatggacctggagcagcagcggcagcttgtg
agcaccctggagaagaagcagcgcaagtttgaccagcttctggcagaggagaaggcagct
gtacttcgggcagtggaggaacgtgagcgggccgaggcagagggccgggagcgtgaggct
cgggccctgtcactgacacgggcactggaggaggagcaggaggcacgtgaggagctggag
cggcagaaccgggccctgcgggctgagctggaggcactgctgagcagcaaggatgacgtc
ggcaagagcgtgcatgagctggaacgagcctgccgggtagcagaacaggcagccaatgat
ctgcgagcacaggtgacagaactggaggatgagctgacagcggccgaggatgccaagctg
cgtctggaggtgactgtgcaggctctcaagactcagcatgagcgtgacctgcagggccgt
gatgaggctggtgaagagaggcggaggcagctggccaagcagctgagagatgcagaggtg
gagcgggatgaggagcggaagcagcgcactctggccgtggctgcccgcaagaagctggag
ggagagctggaggagctgaaggctcagatggcctctgccggccagggcaaggaggaggcg
gtgaagcagcttcgcaagatgcaggcccagatgaaggagctatggcgggaggtggaggag
acacgcacctcccgggaggagatcttctcccagaatcgggaaagtgaaaagcgcctcaag
ggcctggaggctgaggtgctgcggctgcaggaggaactggccgcctcggaccgtgctcgg
cggcaggcccagcaggaccgggatgagatggcagatgaggtggccaatggtaaccttagc
aaggcagccattctggaggagaagcgtcagctggaggggcgcctggggcagttggaggaa
gagctggaggaggagcagagcaactcggagctgctcaatgaccgctaccgcaagctgctc
ctgcaggtagagtcactgaccacagagctgtcagctgagcgcagtttctcagccaaggca
gagagcgggcggcagcagctggaacggcagatccaggagctacggggacgcctgggtgag
gaggatgctggggcccgtgcccgccacaagatgaccattgctgcccttgagtctaagttg
gcccaggctgaggagcagctagagcaagagaccagagagcgcatcctctctggaaagctg
gtgcgcagagctgagaagcggcttaaagaggtggtgctccaggtggaggaggagcggagg
gtggctgaccagctccgggaccagctggagaagggaaaccttcgagtcaagcagctgaag
cggcagctggaggaggccgaggaggaggcatcccgggctcaggccggccgccggaggctg
cagcgtgagctggaagatgtcacagagtcggccgagtccatgaaccgtgaagtgaccaca
ctgaggaaccggcttcgacgcggccccctcaccttcaccacccgcacggtgcgccaggtc
ttccgactagaggagggcgtggcatccgacgaggaggcagaggaagcacagcctgggtct
gggccatccccggagcctgaggggtccccaccagcccacccccagtga
DBGET
integrated database retrieval system
