| Entry |
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| Symbol |
MYH11, AAT4, FAA4, SMHC, SMMHC, SMMS-1, VSCM2
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| Name |
(RefSeq) myosin heavy chain 11
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| KO |
| K10352 | myosin heavy chain 9/10/11/14 |
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| Organism |
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| Pathway |
| hsa03273 | Virion - Lassa virus and SFTS virus |
| hsa04270 | Vascular smooth muscle contraction |
| hsa04810 | Regulation of actin cytoskeleton |
| hsa05130 | Pathogenic Escherichia coli infection |
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| Network |
nt06539 Cytoskeleton in muscle cells |
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| Element |
| N01818 | Actin thin filament, muscle contraction |
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| Disease |
| H00801 | Familial thoracic aortic aneurysm and dissection |
| H01869 | Megacystis microcolon intestinal hypoperistalsis syndrome |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09120 Genetic Information Processing
09125 Information processing in viruses
03273 Virion - Lassa virus and SFTS virus
4629 (MYH11)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04530 Tight junction
4629 (MYH11)
09142 Cell motility
04814 Motor proteins
4629 (MYH11)
04820 Cytoskeleton in muscle cells
4629 (MYH11)
04810 Regulation of actin cytoskeleton
4629 (MYH11)
09150 Organismal Systems
09153 Circulatory system
04270 Vascular smooth muscle contraction
4629 (MYH11)
09160 Human Diseases
09171 Infectious disease: bacterial
05130 Pathogenic Escherichia coli infection
4629 (MYH11)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:hsa04812]
4629 (MYH11)
04147 Exosome [BR:hsa04147]
4629 (MYH11)
Cytoskeleton proteins [BR:hsa04812]
Eukaryotic cytoskeleton proteins
Actin filaments / Microfilaments
Actin-binding proteins
Myosins
4629 (MYH11)
Exosome [BR:hsa04147]
Exosomal proteins
Exosomal proteins of bladder cancer cells
4629 (MYH11)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
16:complement(15703135..15857028)
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| AA seq |
1972 aa
MAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVV
ELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGL
FCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGES
GAGKTENTKKVIQYLAVVASSHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSS
RFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLL
LEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIV
FKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFA
VEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTN
EKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECW
FPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLN
DNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQ
LGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIV
FQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEE
ERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTK
VKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET
ELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE
EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEE
KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAE
LKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQ
KRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQK
HAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQ
VQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDT
QELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL
QDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR
QLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE
ELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATED
AKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK
KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK
KAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ
LEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSK
LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVED
ERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGRE
VNALKSKLRRGNETSFVPSRRSGGRRVIENADGSEEETDTRDADFNGTKASE |
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| NT seq |
5919 nt +upstreamnt +downstreamnt
atggcgcagaagggccaactcagtgacgatgagaagttcctctttgtggacaaaaacttc
atcaacagcccagtggcccaggctgactgggccgccaagagactcgtctgggtcccctcg
gagaagcagggcttcgaggcagccagcattaaggaggagaagggggatgaggtggttgtg
gagctggtggagaatggcaagaaggtcacggttgggaaagatgacatccagaagatgaac
ccacccaagttctccaaggtggaggacatggcggagctgacgtgcctcaacgaagcctcc
gtgctacacaacctgagggagcggtacttctcagggctaatatatacgtactctggcctc
ttctgcgtggtggtcaacccctataaacacctgcccatctactcggagaagatcgtcgac
atgtacaagggcaagaagaggcacgagatgccgcctcacatctacgccatcgcagacacg
gcctaccggagcatgcttcaagatcgggaggaccagtccattctatgcacaggcgagtct
ggagccgggaaaaccgaaaacaccaagaaggtcattcagtacctggccgtggtggcctcc
tcccacaagggcaagaaagacacaagtatcacgggagagctggaaaagcagcttctacaa
gcaaacccgattctggaggctttcggcaacgccaaaacagtgaagaacgacaactcctca
cgattcggcaaattcatccgcatcaacttcgacgtcacgggttacatcgtgggagccaac
attgagacctatctgctagaaaaatcacgggcaattcgccaagccagagacgagaggaca
ttccacatcttttactacatgattgctggagccaaggagaagatgagaagtgacttgctt
ttggagggcttcaacaactacaccttcctctccaatggctttgtgcccatcccagcagcc
caggatgatgagatgttccaggaaaccgtggaggccatggcaatcatgggtttcagcgag
gaggagcagctatccatattgaaggtggtatcatcggtcctgcagcttggaaatatcgtc
ttcaagaaggaaagaaacacagaccaggcgtccatgccagataacacagctgctcagaaa
gtttgccacctcatgggaattaatgtgacagatttcaccagatccatcctcactcctcgt
atcaaggttgggcgagatgtggtacagaaagctcagacaaaagaacaggctgactttgct
gtagaggctttggccaaggcaacatatgagcgccttttccgctggatactcacccgcgtg
aacaaagccctggacaagacccatcggcaaggggcttccttcctggggatcctggatata
gctggatttgagatctttgaggtgaactccttcgagcagctgtgcatcaactacaccaac
gagaagctgcagcagctcttcaaccacaccatgttcatcctggagcaggaggagtaccag
cgcgagggcatcgagtggaacttcatcgactttgggctggacctacagccctgcatcgag
ctcatcgagcgaccgaacaaccctccaggtgtgctggccctgctggacgaggaatgctgg
ttccccaaagccacggacaagtctttcgtggagaagctgtgcacggagcagggcagccac
cccaagttccagaagcccaagcagctcaaggacaagactgagttctccatcatccattat
gctgggaaggtggactataatgcgagtgcctggctgaccaagaatatggacccgctgaat
gacaacgtgacttccctgctcaatgcctcctccgacaagtttgtggccgacctgtggaag
gacgtggaccgcatcgtgggcctggaccagatggccaagatgacggagagctcgctgccc
agcgcctccaagaccaagaagggcatgttccgcacagtggggcagctgtacaaggagcag
ctgggcaagctgatgaccacgctacgcaacaccacgcccaacttcgtgcgctgcatcatc
cccaaccacgagaagaggtccggcaagctggatgcgttcctggtgctggagcagctgcgg
tgcaatggggtgctggaaggcattcgcatctgccggcagggcttccccaaccggatcgtc
ttccaggagttccgccaacgctacgagatcctggcggcgaatgccatccccaaaggcttc
atggacgggaagcaggcctgcattctcatgatcaaagccctggaacttgaccccaactta
tacaggatagggcagagcaaaatcttcttccgaactggcgtcctggcccacctagaggag
gagcgagatttgaagatcaccgatgtcatcatggccttccaggcgatgtgtcgtggctac
ttggccagaaaggcttttgccaagaggcagcagcagctgaccgccatgaaggtgattcag
aggaactgcgccgcctacctcaagctgcggaactggcagtggtggaggcttttcaccaaa
gtgaagccactgctgcaggtgacacggcaggaggaggagatgcaggccaaggaggatgaa
ctgcagaagaccaaggagcggcagcagaaggcagagaatgagcttaaggagctggaacag
aagcactcgcagctgaccgaggagaagaacctgctacaggaacagctgcaggcagagaca
gagctgtatgcagaggctgaggagatgcgggtgcggctggcggccaagaagcaggagctg
gaggagatactgcatgagatggaggcccgcctggaggaggaggaagacaggggccagcag
ctacaggctgaaaggaagaagatggcccagcagatgctggaccttgaagaacagctggag
gaggaggaagctgccaggcagaagctgcaacttgagaaggtcacggctgaggccaagatc
aagaaactggaggatgagatcctggtcatggatgatcagaacaataaactatcaaaagaa
cgaaaactccttgaggagaggattagtgacttaacgacaaatcttgcagaagaggaagaa
aaggccaagaatcttaccaagctgaaaaacaagcatgaatctatgatttcagaactggaa
gtgcggctaaagaaggaagagaagagccgacaggagctggagaagctgaaacggaagctg
gagggtgatgccagcgacttccacgagcagatcgctgacctccaggcgcagatcgcagag
ctcaagatgcagctggccaagaaggaggaggagctgcaggcggccctggccaggcttgac
gatgaaatcgctcagaagaacaatgccctgaagaagatccgggagctggagggccacatc
tcagacctccaggaggacctggactcagagcgggccgccaggaacaaggctgaaaagcag
aagcgagacctcggcgaggagctggaggccctaaagacagagctggaagacacactggac
agcacagccactcagcaggagctcagggccaagagggagcaggaggtgacggtgctgaag
aaggccctggatgaagagacgcggtcccatgaggctcaggtccaggagatgaggcagaaa
cacgcacaggcggtggaggagctcacagagcagcttgagcagttcaagagggccaaggcg
aacctagacaagaataagcagacgctggagaaagagaacgcagacctggccggggagctg
cgggtcctgggccaggccaagcaggaggtggaacataagaagaagaagctggaggcgcag
gtgcaggagctgcagtccaagtgcagcgatggggagcgggcccgggcggagctcaatgac
aaagtccacaagctgcagaatgaagttgagagcgtcacagggatgcttaacgaggccgag
gggaaggccattaagctggccaaggacgtggcgtccctcagttcccagctccaggacacc
caggagctgcttcaagaagaaacccggcagaagctcaacgtgtctacgaagctgcgccag
ctggaggaggagcggaacagcctgcaagaccagctggacgaggagatggaggccaagcag
aacctggagcgccacatctccactctcaacatccagctctccgactcgaagaagaagctg
caggactttgccagcaccgtggaagctctggaagaggggaagaagaggttccagaaggag
atcgagaacctcacccagcagtacgaggagaaggcggccgcttatgataaactggaaaag
accaagaacaggcttcagcaggagctggacgacctggttgttgatttggacaaccagcgg
caactcgtgtccaacctggaaaagaagcagaggaaatttgatcagttgttagccgaggag
aaaaacatctcttccaaatacgcggatgagagggacagagctgaggcagaagccagggag
aaggaaaccaaggccctgtccctggctcgggcccttgaagaggccttggaagccaaagag
gaactcgagcggaccaacaaaatgctcaaagccgaaatggaagacctggtcagctccaag
gatgacgtgggcaagaacgtccatgagctggagaagtccaagcgggccctggagacccag
atggaggagatgaagacgcagctggaagagctggaggacgagctgcaagccacggaggac
gccaaactgcggctggaagtcaacatgcaggcgctcaagggccagttcgaaagggatctc
caagcccgggacgagcagaatgaggagaagaggaggcaactgcagagacagcttcacgag
tatgagacggaactggaagacgagcgaaagcaacgtgccctggcagctgcagcaaagaag
aagctggaaggggacctgaaagacctggagcttcaggccgactctgccatcaaggggagg
gaggaagccatcaagcagctacgcaaactgcaggctcagatgaaggactttcaaagagag
ctggaagatgcccgtgcctccagagatgagatctttgccacagccaaagagaatgagaag
aaagccaagagcttggaagcagacctcatgcagctacaagaggacctcgccgccgctgag
agggctcgcaaacaagcggacctcgagaaggaggaactggcagaggagctggccagtagc
ctgtcgggaaggaacgcactccaggacgagaagcgccgcctggaggcccggatcgcccag
ctggaggaggagctggaggaggagcagggcaacatggaggccatgagcgaccgggtccgc
aaagccacacagcaggccgagcagctcagcaacgagctggccacagagcgcagcacggcc
cagaagaatgagagtgcccggcagcagctcgagcggcagaacaaggagctccggagcaag
ctccacgagatggagggggccgtcaagtccaagttcaagtccaccatcgcggcgctggag
gccaagattgcacagctggaggagcaggtcgagcaggaggccagagagaaacaggcggcc
accaagtcgctgaagcagaaagacaagaagctgaaggaaatcttgctgcaggtggaggac
gagcgcaagatggccgagcagtacaaggagcaggcagagaaaggcaatgccagggtcaag
cagctcaagaggcagctggaggaggcagaggaggagtcccagcgcatcaacgccaaccgc
aggaagctgcagcgggagctggatgaggccacggagagcaacgaggccatgggccgcgag
gtgaacgcactcaagagcaagctcaggcgaggaaacgagacctctttcgttccttctaga
aggtctggaggacgtagagttattgaaaatgcagatggttctgaggaggaaacggacact
cgagacgcagacttcaatggaaccaaggccagtgaataa |
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