Homo sapiens (human): 4646
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Entry
4646 CDS
T01001
Symbol
MYO6, DFNA22, DFNB37
Name
(RefSeq) myosin VI
KO
K10358
myosin VI
Organism
hsa
Homo sapiens (human)
Pathway
hsa04814
Motor proteins
hsa05130
Pathogenic Escherichia coli infection
hsa05132
Salmonella infection
Network
nt06541
Cytoskeleton in neurons
Element
N01852
MYO6-mediated vesicle transport
Disease
H00604
Deafness, autosomal dominant
H00605
Deafness, autosomal recessive
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09142 Cell motility
04814 Motor proteins
4646 (MYO6)
09160 Human Diseases
09171 Infectious disease: bacterial
05130 Pathogenic Escherichia coli infection
4646 (MYO6)
05132 Salmonella infection
4646 (MYO6)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
4646 (MYO6)
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
hsa04812
]
4646 (MYO6)
04147 Exosome [BR:
hsa04147
]
4646 (MYO6)
Membrane trafficking [BR:
hsa04131
]
Others
Actin-binding proteins
Myosins
4646 (MYO6)
Cytoskeleton proteins [BR:
hsa04812
]
Eukaryotic cytoskeleton proteins
Actin filaments / Microfilaments
Actin-binding proteins
Myosins
4646 (MYO6)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
4646 (MYO6)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Myosin_head
MYO6_lever
Myosin-VI_CBD
BUD22
Myosin_N
IQ
XhlA
AAA_16
Motif
Other DBs
NCBI-GeneID:
4646
NCBI-ProteinID:
NP_004990
OMIM:
600970
HGNC:
7605
Ensembl:
ENSG00000196586
Pharos:
Q9UM54
(Tbio)
UniProt:
Q9UM54
Structure
PDB
PDBj
LinkDB
All DBs
Position
6:75749239..75919537
Genome browser
AA seq
1285 aa
AA seq
DB search
MEDGKPVWAPHPTDGFQMGNIVDIGPDSLTIEPLNQKGKTFLALINQVFPAEEDSKKDVE
DNCSLMYLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSEAIKSYQGKSL
GTRPPHVFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLTESYGTGQDIDD
RIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLLEKSRICVQGK
EERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKETDKQILQNRKSPEY
LKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFEEAGSTSG
GCNLKNKSAQSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGTVIKVPLKVEQANNAR
DALAKTVYSHLFDHVVNRVNQCFPFETSSYFIGVLDIAGFEYFEHNSFEQFCINYCNEKL
QQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLIEAKLVGILDILDEENRLPQPSD
QHFTSAVHQKHKDHFRLTIPRKSKLAVHRNIRDDEGFIIRHFAGAVCYETTQFVEKNNDA
LHMSLESLICESRDKFIRELFESSTNNNKDTKQKAGKLSFISVGNKFKTQLNLLLDKLRS
TGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLDLMQGGYPSRASFHELYNMYKK
YMPDKLARLDPRLFCKALFKALGLNENDYKFGLTKVFFRPGKFAEFDQIMKSDPDHLAEL
VKRVNHWLTCSRWKKVQWCSLSVIKLKNKIKYRAEACIKMQKTIRMWLCKRRHKPRIDGL
VKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYD
ALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEM
EAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSE
AELISDEAQADLALRRNDGTRPKMTPEQMAKEMSEFLSRGPAVLATKAAAGTKKYDLSKW
KYAELRDTINTSCDIELLAACREEFHRRLKVYHAWKSKNKKRNTETEQRAPKSVTDYDFA
PFLNNSPQQNPAAQIPARQREIEMNRQQRFFRIPFIRPADQYKDPQSKKKGWWYAHFDGP
WIARQMELHPDKPPILLVAGKDDMEMCELNLEETGLTRKRGAEILPRQFEEIWERCGGIQ
YLQNAIESRQARPTYATAMLQSLLK
NT seq
3858 nt
NT seq
+upstream
nt +downstream
nt
atggaggatggaaagcccgtttgggcgccacaccctacagatggatttcagatgggcaat
attgtggatattggccccgacagcttaacaattgaacccttgaatcagaaaggcaagaca
tttttggctctcataaaccaagtgtttcctgcagaagaggacagtaaaaaagatgtggaa
gataactgttcactaatgtatttaaatgaagccacactgctccataatatcaaagttcga
tatagtaaagacagaatttatacatatgtcgccaacattctgattgcagtgaatccatac
tttgacatacctaaaatatattcttcagaagcaataaagtcatatcaaggaaaatctctt
gggacaagaccacctcatgtctttgcaattgctgataaagcttttcgagacatgaaggtg
ctcaagatgagtcagtctatcattgtatctggagaatcaggagccggcaaaacagaaaat
acaaaatttgttctaagatacctgactgaatcctatggaacaggtcaagatattgatgac
agaattgttgaagctaacccactcctagaagcctttggaaatgcgaagactgttcgcaac
aataatagcagtcgatttgggaaatttgtagaaatacattttaatgaaaagagctcagtt
gttggaggatttgtttcacattatctcctagagaaatctaggatctgtgttcaaggcaaa
gaggaaagaaattatcatatcttttataggttgtgtgctggtgcttctgaagatattaga
gaaaaacttcatttgagttcaccagataattttcggtatttaaaccgaggctgcactaga
tactttgctaacaaagaaactgacaaacagattttacagaaccgcaaaagtcctgagtac
cttaaggcaggttctatgaaagatcctctgctagatgaccatggtgattttattagaatg
tgcacggctatgaaaaaaattggtttggatgatgaagaaaagcttgatctcttccgggta
gtagctggcgtcctgcaccttggaaatattgattttgaggaagctggcagcacttcaggt
ggttgtaatctgaagaataaatctgctcagtctttggaatattgtgctgaattactgggt
ttggaccaagatgatcttcgagtaagtttgaccacaagagtcatgctaacaacagcaggg
ggcaccaaaggaacagttataaaggtacctctgaaagtggagcaagcaaacaatgctcgt
gatgccctggcaaagacagtgtatagccatctttttgatcatgtggtaaacagagtaaat
cagtgttttccttttgaaacatcatcctattttattggagtcctagatattgctggtttt
gagtactttgagcataacagttttgaacaattttgcatcaactattgcaatgaaaaactt
caacaattttttaatgaaaggattctgaaggaggaacaagaactctatcaaaaagaaggt
ttaggtgttaatgaagtgcattatgtggataatcaggactgtatagatttaattgaagcc
aaattagtgggaatactggatattttggatgaagaaaatcgccttccccagccaagtgat
caacactttacatctgcagttcaccaaaagcacaaggatcattttcgactcactattccc
agaaaatctaagctggcagttcataggaatatcagagacgacgaaggcttcattatcagg
cattttgcgggggcagtgtgctatgaaacaacccagtttgtggagaaaaataatgatgct
ttacatatgtctcttgaatccttaatatgtgaatccagagataagtttatacgggaatta
tttgaatcatccacaaataacaacaaagatactaaacaaaaagcaggaaaacttagcttc
atcagcgtgggaaacaagtttaagacacagttaaatttgcttctggataaacttcgaagt
actggagcaagctttattcgttgcatcaaacctaacttaaagatgacaagccaccacttt
gaaggtgctcaaattctgtctcagcttcagtgttcagggatggtgtctgttttggacttg
atgcagggtggttacccatcacgagcttcatttcatgaactctacaacatgtacaaaaag
tatatgccagataaacttgcaagattggatccaagactattttgtaaggctttgtttaaa
gctttgggcttaaatgaaaatgactacaagtttgggttaaccaaagtattttttagacct
ggcaagtttgcagaatttgatcagatcatgaagtctgaccctgaccacttagcagagttg
gttaaaagagtcaatcactggctcacatgcagtcgctggaagaaagttcagtggtgctca
ctctcagtcatcaaattgaaaaacaaaataaaatatcgagctgaagcctgcattaaaatg
caaaaaactattcgaatgtggctttgcaagaggagacacaaacctcgcattgatggtctg
gttaaggtgggcacactgaaaaaacgacttgataaatttaatgaggtagtcagtgtgttg
aaagatggaaaacccgagatgaataaacagatcaagaatctggaaatttctattgatact
ttgatggccaaaattaagtccactatgatgacgcaggaacaaatccagaaagaatatgat
gcactggttaaaagctcagaggaactcctcagtgcattacagaaaaaaaaacagcaggaa
gaggaagcagaaaggctgaggcgtattcaagaagaaatggaaaaggaaagaaaaagacgt
gaagaagacgaaaaacgtcgaagaaaggaagaggaggaaaggcggatgaaacttgagatg
gaagcaaagagaaaacaagaagaagaagagagaaagaaaagggaagatgatgaaaaacgc
attcaagctgaagtggaggcacagctggcccgacagaaggaggaggaatcccaacagcaa
gcagttctggagcaggagcgcagggaccgggagctggccctgaggattgcccagagtgaa
gccgagctcatcagtgatgaggcccaggccgacctggcgctgcggagaaatgatggaaca
agacccaaaatgacaccggaacaaatggccaaagaaatgtcagaatttttgagtagaggt
cctgctgtactagccaccaaagcagctgctggtactaagaaatatgatcttagtaaatgg
aaatatgcagaactacgtgataccatcaatacttcttgtgatattgagctcctggcagct
tgcagagaagaatttcataggagactaaaagtgtatcatgcttggaaatctaagaacaag
aagagaaatactgaaacagagcaacgtgctccaaagtctgttactgattatgattttgca
ccatttttgaacaattcacctcagcaaaacccagcagctcagattcctgccaggcagcgg
gagattgaaatgaaccgacagcaacgcttcttccgcatcccattcatccgccctgccgac
cagtacaaagaccctcagagtaagaaaaaaggctggtggtatgcccattttgatggacca
tggattgcccggcaaatggaactccatcctgacaagccacccatcctacttgtggctggt
aaggacgacatggagatgtgtgagctgaatcttgaggagactggcctgactcggaagcgt
ggtgctgagatcttgccaagacagtttgaagaaatctgggaacgctgtggaggcatccag
taccttcagaatgcgattgagagcagacaggctcggcccacctatgcaacagccatgctg
cagagtctgttaaagtag
DBGET
integrated database retrieval system