Homo sapiens (human): 4647
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Entry
4647 CDS
T01001
Symbol
MYO7A, DFNA11, DFNB2, MYOVIIA, MYU7A, NSRD2, USH1B
Name
(RefSeq) myosin VIIA
KO
K10359
myosin VIIa
Organism
hsa
Homo sapiens (human)
Pathway
hsa04814
Motor proteins
Disease
H00604
Deafness, autosomal dominant
H00605
Deafness, autosomal recessive
H00779
Usher syndrome
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09142 Cell motility
04814 Motor proteins
4647 (MYO7A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
4647 (MYO7A)
09183 Protein families: signaling and cellular processes
03037 Cilium and associated proteins [BR:
hsa03037
]
4647 (MYO7A)
04812 Cytoskeleton proteins [BR:
hsa04812
]
4647 (MYO7A)
Membrane trafficking [BR:
hsa04131
]
Others
Actin-binding proteins
Myosins
4647 (MYO7A)
Cilium and associated proteins [BR:
hsa03037
]
Primary cilia and associated proteins
USH complex and associated proteins
4647 (MYO7A)
Cytoskeleton proteins [BR:
hsa04812
]
Eukaryotic cytoskeleton proteins
Actin filaments / Microfilaments
Actin-binding proteins
Myosins
4647 (MYO7A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Myosin_head
MyTH4
RA_2
FERM_C1_MyoVII
FERM_M
IRS
Myosin_VII_N
IQ
KRIT1_FRMD8_FERM_C
FERM_N
SH3_9
AAA_22
SH3_1
ABC_tran
nSTAND3
PID
AAA_16
Motif
Other DBs
NCBI-GeneID:
4647
NCBI-ProteinID:
NP_000251
OMIM:
276903
HGNC:
7606
Ensembl:
ENSG00000137474
UniProt:
Q13402
Structure
PDB
PDBj
LinkDB
All DBs
Position
11:77128246..77215241
Genome browser
AA seq
2215 aa
AA seq
DB search
MVILQQGDHVWMDLRLGQEFDVPIGAVVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMH
PTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIR
QYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISG
QHSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKS
RVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYAN
IRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLE
VNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYK
PPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLE
SIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIP
PKNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQADVAMG
AETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSG
MMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQ
IGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRG
HNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAV
LTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQER
LAQLAREDAERELKEKEAARRKKELLEQMERARHEPVNHSDMVDKMFGFLGTSGGLPGQE
GQAPSGFEDLERGRREMVEEDLDAALPLPDEDEEDLSEYKFAKFAATYFQGTTTHSYTRR
PLKQPLLYHDDEGDQLAALAVWITILRFMGDLPEPKYHTAMSDGSEKIPVMTKIYETLGK
KTYKRELQALQGEGEAQLPEGQKKSSVRHKLVHLTLKKKSKLTEEVTKRLHDGESTVQGN
SMLEDRPTSNLEKLHFIIGNGILRPALRDEIYCQISKQLTHNPSKSSYARGWILVSLCVG
CFAPSEKFVKYLRNFIHGGPPGYAPYCEERLRRTFVNGTRTQPPSWLELQATKSKKPIML
PVTFMDGTTKTLLTDSATTAKELCNALADKISLKDRFGFSLYIALFDKVSSLGSGSDHVM
DAISQCEQYAKEQGAQERNAPWRLFFRKEVFTPWHSPSEDNVATNLIYQQVVRGVKFGEY
RCEKEDDLAELASQQYFVDYGSEMILERLLNLVPTYIPDREITPLKTLEKWAQLAIAAHK
KGIYAQRRTDAQKVKEDVVSYARFKWPLLFSRFYEAYKFSGPSLPKNDVIVAVNWTGVYF
VDEQEQVLLELSFPEIMAVSSSRECRVWLSLGCSDLGCAAPHSGWAGLTPAGPCSPCWSC
RGAKTTAPSFTLATIKGDEYTFTSSNAEDIRDLVVTFLEGLRKRSKYVVALQDNPNPAGE
ESGFLSFAKGDLIILDHDTGEQVMNSGWANGINERTKQRGDFPTDSVYVMPTVTMPPREI
VALVTMTPDQRQDVVRLLQLRTAEPEVRAKPYTLEEFSYDYFRPPPKHTLSRVMVSKARG
KDRLWSHTREPLKQALLKKLLGSEELSQEACLAFIAVLKYMGDYPSKRTRSVNELTDQIF
EGPLKAEPLKDEAYVQILKQLTDNHIRYSEERGWELLWLCTGLFPPSNILLPHVQRFLQS
RKHCPLAIDCLQRLQKALRNGSRKYPPHLVEVEAIQHKTTQIFHKVYFPDDTDEAFEVES
STKAKDFCQNIATRLLLKSSEGFSLFVKIADKVLSVPENDFFFDFVRHLTDWIKKARPIK
DGIVPSLTYQVFFMKKLWTTTVPGKDPMADSIFHYYQELPKYLRGYHKCTREEVLQLGAL
IYRVKFEEDKSYFPSIPKLLRELVPQDLIRQVSPDDWKRSIVAYFNKHAGKSKEEAKLAF
LKLIFKWPTFGSAFFEVKQTTEPNFPEILLIAINKYGVSLIDPKTKDILTTHPFTKISNW
SSGNTYFHITIGNLVRGSKLLCETSLGYKMDDLLTSYISQMLTAMSKQRGSRSGK
NT seq
6648 nt
NT seq
+upstream
nt +downstream
nt
atggtgattcttcagcagggggaccatgtgtggatggacctgagattggggcaggagttc
gacgtgcccatcggggcggtggtgaagctctgcgactctgggcaggtccaggtggtggat
gatgaagacaatgaacactggatctctccgcagaacgcaacgcacatcaagcctatgcac
cccacgtcggtccacggcgtggaggacatgatccgcctgggggacctcaacgaggcgggc
atcttgcgcaacctgcttatccgctaccgggaccacctcatctacacgtatacgggctcc
atcctggtggctgtgaacccctaccagctgctctccatctactcgccagagcacatccgc
cagtataccaacaagaagattggggagatgcccccccacatctttgccattgctgacaac
tgctacttcaacatgaaacgcaacagccgagaccagtgctgcatcatcagtggggaatct
ggggccgggaagacggagagcacaaagctgatcctgcagttcctggcagccatcagtggg
cagcactcgtggattgagcagcaggtcttggaggccacccccattctggaagcatttggg
aatgccaagaccatccgcaatgacaactcaagccgtttcggaaagtacatcgacatccac
ttcaacaagcggggcgccatcgagggcgcgaagattgagcagtacctgctggaaaagtca
cgtgtctgtcgccaggccctggatgaaaggaactaccacgtgttctactgcatgctggag
ggtatgagtgaggatcagaagaagaagctgggcttgggccaggcctctgactacaactac
ttggccatgggtaactgcataacctgtgagggccgggtggacagccaggagtacgccaac
atccgctccgccatgaaggtgctcatgttcactgacaccgagaactgggagatctcgaag
ctcctggctgccatcctgcacctgggcaacctgcagtatgaggcacgcacatttgaaaac
ctggatgcctgtgaggttctcttctccccatcgctggccacagctgcatccctgcttgag
gtgaaccccccagacctgatgagctgcctgactagccgcaccctcatcacccgcggggag
acggtgtccaccccactgagcagggaacaggcactggacgtgcgcgacgccttcgtaaag
gggatctacgggcggctgttcgtgtggattgtggacaagatcaacgcagcaatttacaag
cctccctcccaggatgtgaagaactctcgcaggtccatcggcctcctggacatctttggg
tttgagaactttgctgtgaacagctttgagcagctctgcatcaacttcgccaatgagcac
ctgcagcagttctttgtgcggcacgtgttcaagctggagcaggaggaatatgacctggag
agcattgactggctgcacatcgagttcactgacaaccaggatgccctggacatgattgcc
aacaagcccatgaacatcatctccctcatcgatgaggagagcaagttccccaagggcaca
gacaccaccatgttacacaagctgaactcccagcacaagctcaacgccaactacatcccc
cccaagaacaaccatgagacccagtttggcatcaaccattttgcaggcatcgtctactat
gagacccaaggcttcctggagaagaaccgagacaccctgcatggggacattatccagctg
gtccactcctccaggaacaagttcatcaagcagatcttccaggccgatgtcgccatgggc
gccgagaccaggaagcgctcgcccacacttagcagccagttcaagcggtcactggagctg
ctgatgcgcacgctgggtgcctgccagcccttctttgtgcgatgcatcaagcccaatgag
ttcaagaagcccatgctgttcgaccggcacctgtgcgtgcgccagctgcggtactcagga
atgatggagaccatccgaatccgccgagctggctaccccatccgctacagcttcgtagag
tttgtggagcggtaccgtgtgctgctgccaggtgtgaagccggcctacaagcagggcgac
ctccgcgggacttgccagcgcatggctgaggctgtgctgggcacccacgatgactggcag
ataggcaaaaccaagatctttctgaaggaccaccatgacatgctgctggaagtggagcgg
gacaaagccatcaccgacagagtcatcctccttcagaaagtcatccggggattcaaagac
aggtctaactttctgaagctgaagaacgctgccacactgatccagaggcactggcggggt
cacaactgtaggaagaactacgggctgatgcgtctgggcttcctgcggctgcaggccctg
caccgctcccggaagctgcaccagcagtaccgcctggcccgccagcgcatcatccagttc
caggcccgctgccgcgcctatctggtgcgcaaggccttccgccaccgcctctgggctgtg
ctcaccgtgcaggcctatgcccggggcatgatcgcccgcaggctgcaccaacgcctcagg
gctgagtatctgtggcgcctcgaggctgagaaaatgcggctggcggaggaagagaagctt
cggaaggagatgagcgccaagaaggccaaggaggaggccgagcgcaagcatcaggagcgc
ctggcccagctggctcgtgaggacgctgagcgggagctgaaggagaaggaggccgctcgg
cggaagaaggagctcctggagcagatggaaagggcccgccatgagcctgtcaatcactca
gacatggtggacaagatgtttggcttcctggggacttcaggtggcctgccaggccaggag
ggccaggcacctagtggctttgaggacctggagcgagggcggagggagatggtggaggag
gacctggatgcagccctgcccctgcctgacgaggatgaggaggacctctctgagtataaa
tttgccaagttcgcggccacctacttccaggggacaaccacgcactcctacacccggcgg
ccactcaaacagccactgctctaccatgacgacgagggtgaccagctggcagccctggcg
gtctggatcaccatcctccgcttcatgggggacctccctgagcccaagtaccacacagcc
atgagtgatggcagtgagaagatccctgtgatgaccaagatttatgagaccctgggcaag
aagacgtacaagagggagctgcaggccctgcagggcgagggcgaggcccagctccccgag
ggccagaagaagagcagtgtgaggcacaagctggtgcatttgactctgaaaaagaagtcc
aagctcacagaggaggtgaccaagaggctgcatgacggggagtccacagtgcagggcaac
agcatgctggaggaccggcccacctccaacctggagaagctgcacttcatcatcggcaat
ggcatcctgcggccagcactccgggacgagatctactgccagatcagcaagcagctgacc
cacaacccctccaagagcagctatgcccggggctggattctcgtgtctctctgcgtgggc
tgtttcgccccctccgagaagtttgtcaagtacctgcggaacttcatccacgggggcccg
cccggctacgccccgtactgtgaggagcgcctgagaaggacctttgtcaatgggacacgg
acacagccgcccagctggctggagctgcaggccaccaagtccaagaagccaatcatgttg
cccgtgacattcatggatgggaccaccaagaccctgctgacggactcggcaaccacggcc
aaggagctctgcaacgcgctggccgacaagatctctctcaaggaccggttcgggttctcc
ctctacattgccctgtttgacaaggtgtcctccctgggcagcggcagtgaccacgtcatg
gacgccatctcccagtgcgagcagtacgccaaggagcagggcgcccaggagcgcaacgcc
ccctggaggctcttcttccgcaaagaggtcttcacgccctggcacagcccctccgaggac
aacgtggccaccaacctcatctaccagcaggtggtgcgaggagtcaagtttggggagtac
aggtgtgagaaggaggacgacctggctgagctggcctcccagcagtactttgtagactat
ggctctgagatgatcctggagcgcctcctgaacctcgtgcccacctacatccccgaccgc
gagatcacgcccctgaagacgctggagaagtgggcccagctggccatcgccgcccacaag
aaggggatttatgcccagaggagaactgatgcccagaaggtcaaagaggatgtggtcagt
tatgcccgcttcaagtggcccttgctcttctccaggttttatgaagcctacaaattctca
ggccccagtctccccaagaacgacgtcatcgtggccgtcaactggacgggtgtgtacttt
gtggatgagcaggagcaggtacttctggagctgtccttcccagagatcatggccgtgtcc
agcagcagggagtgccgtgtctggctctcactgggctgctctgatcttggctgtgctgcg
cctcactcaggctgggcaggactgaccccggcggggccctgttctccgtgttggtcctgc
aggggagcgaaaacgacggcccccagcttcacgctggccaccatcaagggggacgaatac
accttcacctccagcaatgctgaggacattcgtgacctggtggtcaccttcctagagggg
ctccggaagagatctaagtatgttgtggccctgcaggataaccccaaccccgcaggcgag
gagtcaggcttcctcagctttgccaagggagacctcatcatcctggaccatgacacgggc
gagcaggtcatgaactcgggctgggccaacggcatcaatgagaggaccaagcagcgtggg
gacttccccaccgacagtgtgtacgtcatgcccactgtcaccatgccaccgcgggagatt
gtggccctggtcaccatgactcccgatcagaggcaggacgttgtccggctcttgcagctg
cgaacggcggagcccgaggtgcgtgccaagccctacacgctggaggagttttcctatgac
tacttcaggcccccacccaagcacacgctgagccgtgtcatggtgtccaaggcccgaggc
aaggaccggctgtggagccacacgcgggaaccgctcaagcaggcgctgctcaagaagctc
ctgggcagtgaggagctctcgcaggaggcctgcctggccttcattgctgtgctcaagtac
atgggcgactacccgtccaagaggacacgctccgtcaacgagctcaccgaccagatcttt
gagggtcccctgaaagccgagcccctgaaggacgaggcatatgtgcagatcctgaagcag
ctgaccgacaaccacatcaggtacagcgaggagcggggttgggagctgctctggctgtgc
acgggccttttcccacccagcaacatcctcctgccccacgtgcagcgcttcctgcagtcc
cgaaagcactgcccactcgccatcgactgcctgcaacggctccagaaagccctgagaaac
gggtcccggaagtaccctccgcacctggtggaggtggaggccatccagcacaagaccacc
cagattttccacaaagtctacttccctgatgacactgacgaggccttcgaagtggagtcc
agcaccaaggccaaggacttctgccagaacatcgccaccaggctgctcctcaagtcctca
gagggattcagcctctttgtcaaaattgcagacaaggtcctcagcgttcctgagaatgac
ttcttctttgactttgttcgacacttgacagactggataaagaaagctcggcccatcaag
gacggaattgtgccctcactcacctaccaggtgttcttcatgaagaagctgtggaccacc
acggtgccagggaaggatcccatggccgattccatcttccactattaccaggagttgccc
aagtatctccgaggctaccacaagtgcacgcgggaggaggtgctgcagctgggggcgctg
atctacagggtcaagttcgaggaggacaagtcctacttccccagcatccccaagctgctg
cgggagctggtgccccaggaccttatccggcaggtctcacctgatgactggaagcggtcc
atcgtcgcctacttcaacaagcacgcagggaagtccaaggaggaggccaagctggccttc
ctgaagctcatcttcaagtggcccacctttggctcagccttcttcgaggtgaagcaaact
acggagccaaacttccctgagatcctcctaattgccatcaacaagtatggggtcagcctc
atcgatcccaaaacgaaggatatcctcaccactcatcccttcaccaagatctccaactgg
agcagcggcaacacctacttccacatcaccattgggaacttggtgcgcgggagcaaactg
ctctgcgagacgtcactgggctacaagatggatgacctcctgacttcctacattagccag
atgctcacagccatgagcaaacagcggggctccaggagcggcaagtga
DBGET
integrated database retrieval system
