Homo sapiens (human): 4898
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Entry
4898 CDS
T01001
Symbol
NRDC, NRD1, hNRD1, hNRD2
Name
(RefSeq) nardilysin convertase
KO
K01411
nardilysin [EC:
3.4.24.61
]
Organism
hsa
Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
hsa01002
]
4898 (NRDC)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.24 Metalloendopeptidases
3.4.24.61 nardilysin
4898 (NRDC)
Peptidases and inhibitors [BR:
hsa01002
]
Metallo peptidases
Family M16: pitrilysin family
4898 (NRDC)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Peptidase_M16_M
Peptidase_M16_C
Peptidase_M16
PqqF-like_C_4
Nop14
Motif
Other DBs
NCBI-GeneID:
4898
NCBI-ProteinID:
NP_001095132
OMIM:
602651
HGNC:
7995
Ensembl:
ENSG00000078618
UniProt:
O43847
Q6UUU9
LinkDB
All DBs
Position
1:complement(51789210..51878727)
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AA seq
1151 aa
AA seq
DB search
MLRRVTVAAVCATRRKLCEAGRELAALWGIETRGRCEDSAAARPFPILAMPGRNKAKSTC
SCPDLQPNGQDLGENSRVARLGADESEEEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQN
GLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDD
EHDDDLDTEDNELEELEERAEARKKTTEKQSAAALCVGVGSFADPDDLPGLAHFLEHMVF
MGSLKYPDENGFDAFLKKHGGSDNASTDCERTVFQFDVQRKYFKEALDRWAQFFIHPLMI
RDAIDREVEAVDSEYQLARPSDANRKEMLFGSLARPGHPMGKFFWGNAETLKHEPRKNNI
DTHARLREFWMRYYSSHYMTLVVQSKETLDTLEKWVTEIFSQIPNNGLPRPNFGHLTDPF
DTPAFNKLYRVVPIRKIHALTITWALPPQQQHYRVKPLHYISWLVGHEGKGSILSFLRKK
CWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVAYTVFQYLKMLQKLGPEKR
IFEEIRKIEDNEFHYQEQTDPVEYVENMCENMQLYPLQDILTGDQLLFEYKPEVIGEALN
QLVPQKANLVLLSGANEGKCDLKEKWFGTQYSIEDIENSWAELWNSNFELNPDLHLPAEN
KYIATDFTLKAFDCPETEYPVKIVNTPQGCLWYKKDNKFKIPKAYIRFHLISPLIQKSAA
NVVLFDIFVNILTHNLAEPAYEADVAQLEYKLVAGEHGLIIRVKGFNHKLPLLFQLIIDY
LAEFNSTPAVFTMITEQLKKTYFNILIKPETLAKDVRLLILEYARWSMIDKYQALMDGLS
LESLLSFVKEFKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPLEQEMPVQFQVVELP
SGHHLCKVKALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFLRTKQTLGY
HVYPTCRNTSGILGFSVTVGTQATKYNSEVVDKKIEEFLSSFEEKIENLTEEAFNTQVTA
LIKLKECEDTHLGEEVDRNWNEVVTQQYLFDRLAHEIEALKSFSKSDLVNWFKAHRGPGS
KMLSVHVVGYGKYELEEDGTPSSEDSNSSCEVMQLTYLPTSPLLADCIIPITDIRAFTTT
LNLLPYHKIVK
NT seq
3456 nt
NT seq
+upstream
nt +downstream
nt
atgctgaggagagtcactgttgctgcagtctgtgccacccggaggaagttgtgtgaggcc
gggcgggagctcgcggcgctctggggaatcgaaacgcggggtcggtgcgaagactctgct
gctgccagaccctttcctattctggccatgcctggaaggaacaaggcgaagtctacctgc
agctgccctgacctgcagcccaatggacaggatctgggcgagaacagccgggttgcccgt
ctaggagcggatgaatctgaggaagagggacggagggggtctctcagtaatgctggggac
cctgagatcgtcaagtctcccagcgaccccaagcaataccgatacatcaaattacagaat
ggcttgcaggcacttctgatttcagacctaagtaatatggaaggtaaaacaggaaataca
acagatgatgaagaagaagaggaggtggaggaagaagaagaagatgatgatgaagattct
ggagctgaaatagaagatgacgatgaagagggttttgatgatgaagatgagtttgatgat
gaacatgatgatgatcttgatactgaggataatgaattggaagaattagaagagagagca
gaagctagaaaaaaaactactgaaaaacagtctgcagcggctctttgtgttggagttggg
agtttcgctgatccagatgacctgccggggctggcacactttttggagcacatggtattc
atgggtagtttgaaatatccagatgagaatggatttgatgccttcctgaagaagcatggg
ggtagtgataatgcctcaactgattgtgaacgcactgtctttcagtttgatgtccagagg
aagtacttcaaggaagctcttgatagatgggcgcagttcttcatccacccactaatgatc
agagatgcaattgaccgtgaagttgaagctgttgatagtgaatatcaacttgcaaggcct
tctgatgcaaacagaaaggaaatgttgtttggaagccttgctagacctggacatcctatg
ggaaaatttttttggggaaatgctgagacgctcaagcatgagccaagaaagaataatatt
gatacacatgctagattgagagaattctggatgcgttactactcttctcattacatgact
ttagtggttcaatccaaagaaacactggatactttggaaaagtgggtgactgaaatcttc
tctcagataccaaacaatgggttacccagaccaaactttggccatttaacggatccattt
gacacaccagcatttaacaaactttatagagttgttccaatcagaaaaattcatgctctg
accatcacatgggcacttcctcctcaacagcaacattacagggtgaagccacttcattat
atatcctggctggttggacatgaaggcaaaggcagcattctttctttccttaggaaaaaa
tgctgggctcttgcactgtttggtggaaatggtgagacaggatttgagcaaaattctact
tattcagtgttcagcatttctattacattgactgatgagggttatgaacatttttatgag
gttgcttacactgtctttcagtatttaaaaatgctgcagaagctaggcccagaaaaaaga
atttttgaagagattcggaaaattgaggataatgaatttcattaccaagaacagacagat
ccagttgagtatgtggaaaacatgtgtgagaacatgcagctgtacccattgcaggacatt
ctcactggagatcagcttctttttgaatacaagccagaagtcattggtgaagccttgaat
cagctagttcctcaaaaagcaaatcttgttttactgtctggtgctaatgagggaaaatgt
gacctcaaggagaaatggtttggaactcaatatagtatagaagatattgaaaactcttgg
gctgaactgtggaatagtaatttcgaattaaatccagatcttcatcttccagctgaaaac
aagtacatagccacggactttacgttgaaggctttcgattgcccggaaacagaataccca
gttaaaattgtgaatactccacaaggttgcctgtggtataagaaagacaacaaattcaaa
atccccaaagcatatatacgtttccatctaatttcaccgttgatacagaaatctgcagca
aatgtggtcctctttgatatctttgtcaatatccttacgcataaccttgcggaaccagct
tatgaagcagatgtggcacagctggagtataaactggtagctggagaacatggtttaatt
attcgagtgaaaggatttaaccacaaactacctctactgtttcagctcattattgactac
ttagctgagttcaattccacaccagctgtctttacaatgataactgagcagttgaagaag
acctactttaacatcctcatcaagcccgagactttggccaaagatgtacggcttttaatc
ttggaatatgcccgttggtctatgattgacaagtaccaggctttgatggacggcctttcc
cttgagtctctgctgagcttcgtcaaagaattcaaatcccagctctttgtggagggcctg
gtacaagggaatgtcacaagcacagaatctatggatttcctgaaatatgttgttgacaaa
ctaaacttcaagcctctggagcaggagatgcctgtgcagttccaggtggtagagctgccc
agtggccaccatctatgcaaagtgaaagctctgaacaagggtgatgccaactctgaagtc
actgtgtactaccagtcaggtaccaggagtctaagagaatatacgcttatggagctgctt
gtgatgcacatggaagaaccttgttttgacttccttcgaaccaagcagacccttgggtac
catgtctaccctacctgtaggaacacatccgggattctaggattttctgtcactgtgggg
actcaggcaaccaaatacaattctgaagttgttgataagaagatagaagagtttctttct
agctttgaggagaagattgagaacctcactgaagaggcattcaacacccaggtcacagct
ctcatcaagctgaaggagtgtgaggatacccaccttggggaggaggtggataggaactgg
aatgaagtggttacacagcagtacctctttgaccgccttgcccacgagattgaagcactg
aagtcattctcaaaatcagacctggtcaactggttcaaggcccatagagggccaggaagt
aaaatgctcagcgttcatgttgttggatatgggaagtatgaactggaagaggatggtacc
ccttctagtgaggattcaaattcttcttgtgaagtgatgcagctgacctacctgccaacc
tctcctctgctggcagattgtatcatccccattactgatatcagggctttcacaacaaca
ctcaaccttctcccctaccataaaatagtcaaataa
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