Homo sapiens (human): 4905
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Entry
4905 CDS
T01001
Symbol
NSF, DEE96, SEC18, SKD2
Name
(RefSeq) N-ethylmaleimide sensitive factor, vesicle fusing ATPase
KO
K06027
vesicle-fusing ATPase [EC:
3.6.4.6
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04721
Synaptic vesicle cycle
hsa04727
GABAergic synapse
hsa04962
Vasopressin-regulated water reabsorption
Disease
H00606
Early infantile epileptic encephalopathy
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09155 Excretory system
04962 Vasopressin-regulated water reabsorption
4905 (NSF)
09156 Nervous system
04727 GABAergic synapse
4905 (NSF)
04721 Synaptic vesicle cycle
4905 (NSF)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
4905 (NSF)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.6 Acting on acid anhydrides
3.6.4 Acting on acid anhydrides to facilitate cellular and subcellular movement
3.6.4.6 vesicle-fusing ATPase
4905 (NSF)
Membrane trafficking [BR:
hsa04131
]
SNARE
SNARE associated proteins
Others
4905 (NSF)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AAA
NSF_ATPase_lid
CDC48_N
AAA_lid_3
CDC48_2
AAA_22
RNA_helicase
RuvB_N
AAA_16
AAA_14
AAA_5
TIP49
AAA_18
nSTAND3
ATPase_2
Mg_chelatase
AAA_2
AAA_33
AAA_17
AAA_24
NACHT
TsaE
AAA_28
Parvo_NS1
ABC_tran
NB-ARC
AAA_7
ATPase
AAA_3
IstB_IS21
Rad17
AAA_19
bpMoxR
Motif
Other DBs
NCBI-GeneID:
4905
NCBI-ProteinID:
NP_006169
OMIM:
601633
HGNC:
8016
Ensembl:
ENSG00000073969
Pharos:
P46459
(Tbio)
UniProt:
P46459
A0A384MTI6
Structure
PDB
PDBj
LinkDB
All DBs
Position
17:46590669..46757464
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AA seq
744 aa
AA seq
DB search
MAGRSMQAARCPTDELSLTNCAVVNEKDFQSGQHVIVRTSPNHRYTFTLKTHPSVVPGSI
AFSLPQRKWAGLSIGQEIEVSLYTFDKAKQCIGTMTIEIDFLQKKSIDSNPYDTDKMAAE
FIQQFNNQAFSVGQQLVFSFNEKLFGLLVKDIEAMDPSILKGEPATGKRQKIEVGLVVGN
SQVAFEKAENSSLNLIGKAKTKENRQSIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVF
PPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEA
NIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDG
VEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLL
SADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIKASTKVEVDMEKAESLQVTRGDF
LASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVL
LEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCV
VVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNA
FSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQM
DPEYRVRKFLALLREEGASPLDFD
NT seq
2235 nt
NT seq
+upstream
nt +downstream
nt
atggcgggccggagcatgcaagcggcaagatgtcctacagatgaattatctttaaccaat
tgtgcagttgtgaatgaaaaggatttccagtctggccagcatgtgattgtgaggacctct
cccaatcacaggtacacatttacactgaagacacatccatcggtggttccagggagcatt
gcattcagtttacctcagagaaaatgggctgggctttctattgggcaagaaatagaagtc
tccttatatacatttgacaaagccaaacagtgtattggcacaatgaccatcgagattgat
ttcctgcagaaaaaaagcattgactccaacccttatgacaccgacaagatggcagcagaa
tttattcagcaattcaacaaccaggccttctcagtgggacaacagcttgtctttagcttc
aatgaaaagctttttggcttactggtgaaggacattgaagccatggatcctagcatcctg
aagggagagcctgcgacagggaaaaggcagaagattgaagtaggactggttgttggaaac
agtcaagttgcatttgaaaaagcagaaaattcgtcacttaatcttattggcaaagctaaa
accaaggaaaatcgccaatcaattatcaatcctgactggaactttgaaaaaatgggaata
ggaggtctagacaaggaattttcagatattttccgacgagcatttgcttcccgagtattt
cctccagagattgtggagcagatgggttgtaaacatgttaaaggcatcctgttatatgga
cccccaggttgtggtaagactctcttggctcgacagattggcaagatgttgaatgcaaga
gagcccaaagtggtcaatgggccagaaatccttaacaaatatgtgggagaatcagaggct
aacattcgcaaactttttgctgatgctgaagaggagcaaaggaggcttggtgctaacagt
ggtttgcacatcatcatctttgatgaaattgatgccatctgcaagcagagagggagcatg
gctggtagcacgggagttcatgacactgttgtcaaccagttgctgtccaaaattgatggc
gtggagcagctaaacaacatcctagtcattggaatgaccaatagaccagatctgatagat
gaggctcttcttagacctggaagactggaagttaaaatggagataggcttgccagatgag
aaaggccgactacagattcttcacatccacacagcaagaatgagagggcatcagttactc
tctgctgatgtagacattaaagaactggccgtggagaccaagaatttcagtggtgctgaa
ttggagggtctggtgcgagcagcccagtccactgctatgaatagacacataaaggccagt
actaaagtggaagtggacatggagaaagcagaaagcctgcaagtgacgagaggagacttc
cttgcttctttggagaatgatatcaaaccagcctttggcacaaaccaagaagattatgca
agttacattatgaacggtatcatcaaatggggtgacccagttactcgagttctagatgat
ggggagctgctggtgcagcagactaagaacagtgaccgcacaccattggtcagcgtgctt
ctggaaggccctcctcacagtgggaagactgctttagctgcaaaaattgcagaggaatcc
aacttcccgttcatcaagatctgttctcctgataaaatgattggcttttctgaaacagcc
aaatgtcaggccatgaagaagatctttgatgatgcgtacaaatcccagctcagttgtgtg
gttgtggatgacattgagagattgcttgattacgtccctattggccctcgattttcaaat
cttgtattacaggctcttctcgttttactgaaaaaggcacctcctcagggccgcaagctt
cttatcattgggaccactagccgcaaagatgtccttcaggagatggaaatgcttaacgct
ttcagcaccaccatccacgtgcccaacattgccacaggagagcagctgttggaagctttg
gagcttttgggcaacttcaaggataaggaacgcaccacaattgcacagcaagtcaaaggg
aagaaggtctggataggaatcaagaagttactaatgctgatcgagatgtccctacagatg
gatcctgaataccgtgtgagaaaattcttggccctcttaagagaagaaggagctagcccc
cttgattttgattga
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