KEGG   Homo sapiens (human): 5048
Entry
5048              CDS       T01001                                 
Symbol
PAFAH1B1, LIS1, LIS2, MDCR, MDS, NudF, PAFAH
Name
(RefSeq) platelet-activating factor acetylhydrolase IB subunit beta
  KO
K16794  platelet-activating factor acetylhydrolase IB subunit alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa00565  Ether lipid metabolism
hsa01100  Metabolic pathways
Network
nt06515  Regulation of kinetochore-microtubule interactions
nt06541  Cytoskeleton in neurons
  Element
N01534  Dynein recruitment to the kinetochore
N01847  Regulation of dynein-mediated retrograde transport
Disease
H00268  Lissencephaly
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00565 Ether lipid metabolism
    5048 (PAFAH1B1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    5048 (PAFAH1B1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    5048 (PAFAH1B1)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centrosome formation proteins
   Spindle formation proteins
    5048 (PAFAH1B1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   5048 (PAFAH1B1)
SSDB
Motif
Pfam: Beta-prop_WDR5 Beta-prop_WDR3_1st WD40 Beta-prop_IFT122_1st Beta-prop_THOC3 WD40_Prp19 Beta-prop_WDR3_2nd WD40_WDHD1_1st WD40_CDC20-Fz EIF3I WD40_Gbeta Beta-prop_CAF1B_HIR1 Beta-prop_WDR36-Utp21_2nd WD40_MABP1-WDR62_2nd WDR55 Beta-prop_TEP1_2nd Beta-prop_EML_2 Beta-prop_WDR75_1st Beta-prop_TEP1_C Beta-prop_WDR36-Utp21_1st DSE1_N Beta-prop_EIPR1 Beta-prop_Aladin WD40_MABP1-WDR62_1st Beta-prop_WDR90_POC16_2nd Beta-prop_WDR41 ANAPC4_WD40 LisH_PAC1 Beta-prop_EML ASA1 NBCH_WD40 Beta-prop_SCAP Beta-prop_Vps41 PAC11 CFAP251_N WDR90_beta-prop_4th Beta-prop_Nup120_160 Beta-prop_DCAF4 WD40_RFWD3 TRM82_WD Beta-prop_SPT8 Beta-prop_NOL10_N LisH Beta-prop_DCAF12 Beta-prop_RIG_2nd Beta-prop_IFT140_1st SHKBP1_KCTD3_C eIF2A Beta-prop_WDR75_2nd Beta-prop_WDR19_1st Nucleoporin_N Beta-prop_ACSF4 Ge1_WD40 Beta-prop_WDR35_TULP_N Beta-prop_NUP159_NUP214 Pox_A_type_inc LisH_SSDP Beta-prop_WDR11_2nd LisH_UCP007778 ARMC9_LisH LisH_2 SutA-RBD
Other DBs
NCBI-GeneID: 5048
NCBI-ProteinID: NP_000421
OMIM: 601545
HGNC: 8574
Ensembl: ENSP00000380378.4
UniProt: P43034
Structure
LinkDB
Position
17:2593183..2685615
AA seq 410 aa
MVLSQRQRDELNRAIADYLRSNGYEEAYSVFKKEAELDVNEELDKKYAGLLEKKWTSVIR
LQKKVMELESKLNEAKEEFTSGGPLGQKRDPKEWIPRPPEKYALSGHRSPVTRVIFHPVF
SVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQ
GFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMV
RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSE
TKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDK
TLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR
NT seq 1233 nt   +upstreamnt  +downstreamnt
atggtgctgtcccagagacaacgagatgaactaaatcgagctatagcagattatcttcgt
tcaaatggctatgaagaggcatattcagtttttaaaaaggaagctgaattagatgtgaat
gaagaattagataaaaagtatgctggtcttttggaaaaaaaatggacatctgttattaga
ttacaaaagaaggttatggaattagaatcaaagctaaatgaagcaaaagaagaatttacg
tcaggtggacctcttggtcagaaacgagacccaaaagaatggattccccgtccgccagaa
aaatatgcattgagtggtcacaggagtccagtcactcgagtcattttccatcctgtgttc
agtgttatggtctctgcttcagaggatgctacaattaaggtgtgggattatgagactgga
gattttgaacgaactcttaaaggacatacagactctgtacaggacatttcattcgaccac
agcggcaagcttctggcttcctgttctgcagatatgaccattaaactatgggattttcag
ggctttgaatgcatcagaaccatgcacggccatgaccacaatgtttcttcagtagccatc
atgcccaatggagatcatatagtgtctgcctcaagggataaaactataaaaatgtgggaa
gtgcaaactggctactgtgtgaagacattcacaggacacagagaatgggtacgtatggta
cggccaaatcaagatggcactctgatagccagctgttccaatgaccagactgtgcgtgta
tgggtcgtagcaacaaaggaatgcaaggctgagctccgagagcatgagcatgtggtagaa
tgcatttcctgggctccagaaagctcatattcctccatctctgaagcaacaggatctgag
actaaaaaaagtggtaaacctgggccattcttgctgtctggatccagagacaagactatt
aagatgtgggatgtcagtactggcatgtgccttatgaccctcgtgggtcatgataactgg
gtacgtggagttctgttccattctggggggaagtttattttgagttgtgctgatgacaag
accctacgcgtatgggattacaagaacaagcgatgcatgaagaccctcaatgcgcatgaa
cactttgttacctccttggatttccacaagacggcaccctatgtcgtcactggcagcgta
gatcaaacagtaaaagtgtgggagtgccgttga

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