Homo sapiens (human): 50649
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Entry
50649 CDS
T01001
Symbol
ARHGEF4, ASEF, ASEF1, GEF4, SMIM39, STM6
Name
(RefSeq) Rho guanine nucleotide exchange factor 4
KO
K05769
Rho guanine nucleotide exchange factor 4/29
Organism
hsa
Homo sapiens (human)
Pathway
hsa04810
Regulation of actin cytoskeleton
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
50649 (ARHGEF4)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
50649 (ARHGEF4)
Membrane trafficking [BR:
hsa04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
50649 (ARHGEF4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RhoGEF
SOS1_NGEF_PH
SH3_1
PH
SH3_2
SH3_9
RHG20_PH
Motif
Other DBs
NCBI-GeneID:
50649
NCBI-ProteinID:
NP_056135
OMIM:
605216
HGNC:
684
Ensembl:
ENSG00000136002
UniProt:
Q9NR80
Q9NTG0
Structure
PDB
PDBj
LinkDB
All DBs
Position
2:130836914..131047253
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AA seq
690 aa
AA seq
DB search
MPWEEPAGEKPSCSHSQKAFHMEPAQKPCFTTDMVTWALLCISAETVRGEAPSQPRGIPH
RSPVSVDDLWLEKTQRKKLQKQAHVERRLHIGAVHKDGVKCWRKTIITSPESLNLPRRSH
PLSQSAPTGLNHMGWPEHTPGTAMPDGALDTAVCADEVGSEEDLYDDLHSSSHHYSHPGG
GGEQLAINELISDGSVVCAEALWDHVTMDDQELGFKAGDVIEVMDATNREWWWGRVADGE
GWFPASFVRLRVNQDEPADDDAPLAGNSGAEDGGAEAQSSKDQMRTNVINEILSTERDYI
KHLRDICEGYVRQCRKRADMFSEEQLRTIFGNIEDIYRCQKAFVKALEQRFNRERPHLSE
LGACFLEHQADFQIYSEYCNNHPNACVELSRLTKLSKYVYFFEACRLLQKMIDISLDGFL
LTPVQKICKYPLQLAELLKYTHPQHRDFKDVEAALHAMKNVAQLINERKRRLENIDKIAQ
WQSSIEDWEGEDLLVRSSELIYSGELTRVTQPQAKSQQRMFFLFDHQLIYCKKDLLRRDV
LYYKGRLDMDGLEVVDLEDGKDRDLHVSIKNAFRLHRGATGDSHLLCTRKPEQKQRWLKA
FAREREQVQLDQETGFSITELQRKQAMLNASKQQVTGKPKAVGRPCYLTRQKHPALPSNR
PQQQVLVLAEPRRKPSTFWHSISRLAPFRK
NT seq
2073 nt
NT seq
+upstream
nt +downstream
nt
atgccctgggaagaaccagcaggtgagaagcccagttgctctcacagtcagaaggcgttc
cacatggagcctgcccagaagccctgcttcaccactgacatggtgacatgggccctcctc
tgcatctctgcagagactgtgcgtggggaggctccttcacagcctaggggcatccctcac
cgctcgcccgtcagtgtggatgacctgtggctggagaagacacagagaaagaagttgcag
aagcaggcccacgtcgaaaggaggctgcacataggggcagtgcacaaagatggagtcaag
tgctggagaaagacgatcattacctctccagagtctttgaatctccctagaagaagccat
ccactctcccagagtgctccaacgggactgaaccacatgggctggccagagcacacacca
ggcactgccatgcctgatggagctctggacacagctgtctgcgctgacgaagtggggagc
gaggaggacctgtatgatgacctgcacagctccagccaccactacagccaccctggaggg
ggtggggagcagctggctatcaatgagctcatcagcgatggcagtgtggtctgcgctgaa
gcactctgggaccatgtcaccatggacgaccaggagctgggcttcaaagctggggacgtc
atcgaagtgatggatgccaccaacagagagtggtggtggggccgggtcgccgatggcgag
ggctggtttccagccagcttcgttcggctgagggtgaatcaggacgagcccgcggatgac
gacgcccctctggccgggaacagcggagcggaggacggcggggcggaggcgcagagcagc
aaggaccagatgcggaccaacgtcatcaacgagatcctcagcactgagcgggactacatc
aagcacctgcgcgacatctgcgagggctacgtccggcagtgccgcaagcgcgcagacatg
ttcagcgaggagcagctgcgtaccatcttcgggaacatcgaggacatctaccgctgccag
aaggccttcgtgaaggccctggagcagaggttcaaccgcgagcgcccacacctgagcgag
ctgggtgcctgcttcctggagcatcaagccgacttccagatctactcggagtactgcaat
aaccaccccaacgcctgcgtggagctctcccggctcaccaagctcagcaagtacgtgtac
ttcttcgaggcctgccggctgctgcagaagatgattgacatctccctggatggcttcctg
ctgactccggtgcagaagatctgcaagtaccctctgcagctggccgagctgctcaaatac
acgcacccccagcacagggacttcaaggatgttgaagccgccttgcatgccatgaagaac
gtggcccagctcatcaacgagcggaagcggagacttgagaacatcgacaagattgctcag
tggcagagctccatagaggactgggagggagaagatctcttggtcaggagctcagaactc
atctactcgggggagctgactcgagttacacagcctcaagccaaaagccagcagcgaatg
ttctttctctttgaccaccagctcatctactgtaagaaggacctgctccgccgcgacgtg
ttgtactacaagggccggctggacatggacggcctggaggtggtggacctggaggacggg
aaggacagagacctccatgtgagcatcaagaacgccttccggctgcaccgtggcgccaca
ggggacagccacctgctgtgcaccaggaagcccgagcagaagcagcgctggctcaaggcc
tttgccagggagagggagcaggtgcagctggaccaggagacaggcttctccatcactgaa
ctgcagaggaagcaggccatgctgaatgccagcaagcagcaggtcacagggaagcccaaa
gctgttggccggccctgctacctgacgcgccagaagcacccagccctgcccagcaaccgg
ccccagcagcaggtcctggtgctggcggagcccaggcgcaagccatctaccttctggcac
agcatcagccggctggcacccttccgcaagtga
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