Homo sapiens (human): 5077 Help Entry 5077              CDS       T01001                                  Symbol PAX3, CDHS, HUP2, PAX-3, WS1, WS3 Name (RefSeq) paired box 3   KO K09381   paired box protein 3/7 Organism hsa  Homo sapiens (human) Pathway hsa05202   Transcriptional misregulation in cancer Disease H00037   Rhabdomyosarcoma H00446   Craniofacial-deafness-hand syndrome H00759   Waardenburg syndrome Brite KEGG Orthology (KO) [BR:hsa00001]  09160 Human Diseases   09161 Cancer: overview    05202 Transcriptional misregulation in cancer     5077 (PAX3)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03000 Transcription factors [BR:hsa03000]     5077 (PAX3) Transcription factors [BR:hsa03000]  Eukaryotic type   Helix-turn-helix    Homeo domain Paired-related     5077 (PAX3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PAX Pax7 Homeodomain HTH_32 HTH_23 Homeobox_KN HTH_Tnp_IS1 DUF6033 Motif Other DBs NCBI-GeneID:  5077 NCBI-ProteinID:  NP_852122 OMIM:  606597 HGNC:  8617 Ensembl:  ENSG00000135903 UniProt:  P23760 Structure PDB LinkDB All DBs Position 2:complement(222199887..222298998) Genome browser AA seq 479 aa AA seqDB search MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE YKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFGKGEEEEADLERKEAEES EKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFER THYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMP TLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTR HGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQTDYALSPLTGGLE PTTTVSASCSQRLDHMKSLDSLPTSQSYCPPTYSTTGYSMDPVTGYQYGQYGQSKPWTF NT seq 1440 nt NT seq  +upstreamnt  +downstreamnt atgaccacgctggccggcgctgtgcccaggatgatgcggccgggcccggggcagaactac ccgcgtagcgggttcccgctggaagtgtccactcccctcggccagggccgcgtcaaccag ctcggcggtgtttttatcaacggcaggccgctgcccaaccacatccgccacaagatcgtg gagatggcccaccacggcatccggccctgcgtcatctcgcgccagctgcgcgtgtcccac ggctgcgtctccaagatcctgtgcaggtaccaggagactggctccatacgtcctggtgcc atcggcggcagcaagcccaagcaggtgacaacgcctgacgtggagaagaaaattgaggaa tacaaaagagagaacccgggcatgttcagctgggaaatccgagacaaattactcaaggac gcggtctgtgatcgaaacaccgtgccgtcagtgagttccatcagccgcatcctgagaagt aaattcgggaaaggtgaagaggaggaggccgacttggagaggaaggaggcagaggaaagc gagaagaaggccaaacacagcatcgacggcatcctgagcgagcgagcctcagcaccccaa tcagatgaaggctctgatattgactctgaaccagatttaccactaaagaggaaacagcgc agaagccgaaccaccttcacagcagaacagctggaggaactggagcgtgcttttgagaga actcattaccctgacatttatactagggaggaactggcccagagggcgaagctcaccgag gcccgagtacaggtctggtttagcaaccgccgtgcaagatggaggaagcaagctggggcc aatcaactgatggctttcaaccatctcattcccggggggttccctcccactgccatgccg accttgccaacgtaccagctgtcggagacctcttaccagcccacatctattccacaagct gtgtcagatcccagcagcaccgttcacagacctcaaccgcttcctccaagcactgtacac caaagcacgattccttccaacccagacagcagctctgcctactgcctccccagcaccagg catggattttccagctatacagacagctttgtgcctccgtcggggccctccaaccccatg aaccccaccattggcaatggcctctcacctcaggtaatgggactcctgaccaaccacggt ggggtacctcatcagccccagactgattacgcgctctcccctctcaccgggggtctggaa cctaccaccacggtgtcggccagctgcagtcagagactagaccatatgaagagcttggac agtctgccaacatctcagtcctactgtccacccacctatagcaccacaggctacagtatg gaccctgtcacaggctaccaatatgggcagtatggacaaagtaagccttggactttttag

Homo sapiens (human): 2308 Help Entry 2308              CDS       T01001                                  Symbol FOXO1, FKH1, FKHR, FOXO1A Name (RefSeq) forkhead box O1   KO K07201   forkhead box protein O1 Organism hsa  Homo sapiens (human) Pathway hsa04068   FoxO signaling pathway hsa04152   AMPK signaling pathway hsa04211   Longevity regulating pathway hsa04213   Longevity regulating pathway - multiple species hsa04218   Cellular senescence hsa04910   Insulin signaling pathway hsa04919   Thyroid hormone signaling pathway hsa04922   Glucagon signaling pathway hsa04931   Insulin resistance hsa04933   AGE-RAGE signaling pathway in diabetic complications hsa04936   Alcoholic liver disease hsa05131   Shigellosis hsa05165   Human papillomavirus infection hsa05200   Pathways in cancer hsa05202   Transcriptional misregulation in cancer hsa05215   Prostate cancer Network nt06240  Transcription (cancer)   Element N00141   PAX3-FOXO1 fusion to transcriptional activation Disease H00037   Rhabdomyosarcoma H02434   Diffuse large B-cell lymphoma, not otherwise specified Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     2308 (FOXO1)    04152 AMPK signaling pathway     2308 (FOXO1)  09140 Cellular Processes   09143 Cell growth and death    04218 Cellular senescence     2308 (FOXO1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     2308 (FOXO1)    04922 Glucagon signaling pathway     2308 (FOXO1)    04919 Thyroid hormone signaling pathway     2308 (FOXO1)   09149 Aging    04211 Longevity regulating pathway     2308 (FOXO1)    04213 Longevity regulating pathway - multiple species     2308 (FOXO1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     2308 (FOXO1)    05202 Transcriptional misregulation in cancer     2308 (FOXO1)   09162 Cancer: specific types    05215 Prostate cancer     2308 (FOXO1)   09172 Infectious disease: viral    05165 Human papillomavirus infection     2308 (FOXO1)   09171 Infectious disease: bacterial    05131 Shigellosis     2308 (FOXO1)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     2308 (FOXO1)    04931 Insulin resistance     2308 (FOXO1)    04933 AGE-RAGE signaling pathway in diabetic complications     2308 (FOXO1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03000 Transcription factors [BR:hsa03000]     2308 (FOXO1) Transcription factors [BR:hsa03000]  Eukaryotic type   Helix-turn-helix    Fork head/winged helix other regulators     2308 (FOXO1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  FOXO_KIX_bdg Forkhead FOXO-TAD Motif Other DBs NCBI-GeneID:  2308 NCBI-ProteinID:  NP_002006 OMIM:  136533 HGNC:  3819 Ensembl:  ENSG00000150907 UniProt:  Q12778 Structure PDB LinkDB All DBs Position 13:complement(40555667..40666641) Genome browser AA seq 655 aa AA seqDB search MAEAPQVVEIDPDFEPLPRPRSCTWPLPRPEFSQSNSATSSPAPSGSAAANPDAAAGLPS ASAAAVSADFMSNLSLLEESEDFPQAPGSVAAAVAAAAAAAATGGLCGDFQGPEAGCLHP APPQPPPPGPLSQHPPVPPAAAGPLAGQPRKSSSSRRNAWGNLSYADLITKAIESSAEKR LTLSQIYEWMVKSVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIRVQNEGTGKSSWWMLN PEGGKSGKSPRRRAASMDNNSKFAKSRSRAAKKKASLQSGQEGAGDSPGSQFSKWPASPG SHSNDDFDNWSTFRPRTSSNASTISGRLSPIMTEQDDLGEGDVHSMVYPPSAAKMASTLP SLSEISNPENMENLLDNLNLLSSPTSLTVSTQSSPGTMMQQTPCYSFAPPNTSLNSPSPN YQKYTYGQSSMSPLPQMPIQTLQDNKSSYGGMSQYNCAPGLLKELLTSDSPPHNDIMTPV DPGVAQPNSRVLGQNVMMGPNSVMSTYGSQASHNKMMNPSSHTHPGHAQQTSAVNGRPLP HTVSTMPHTSGMNRLTQVKTPVQVPLPHPMQMSALGGYSSVSSCNGYGRMGLLHQEKLPS DLDGMFIERLDCDMESIIRNDLMDGDTLDFNFDNVLPNQSFPHSVKTTTHSWVSG NT seq 1968 nt NT seq  +upstreamnt  +downstreamnt atggccgaggcgcctcaggtggtggagatcgacccggacttcgagccgctgccccggccg cgctcgtgcacctggccgctgcccaggccggagtttagccagtccaactcggccacctcc agcccggcgccgtcgggcagcgcggctgccaaccccgacgccgcggcgggcctgccctcg gcctcggctgccgctgtcagcgccgacttcatgagcaacctgagcttgctggaggagagc gaggacttcccgcaggcgcccggctccgtggcggcggcggtggcggcggcggccgccgcg gccgccaccggggggctgtgcggggacttccagggcccggaggcgggctgcctgcaccca gcgccaccgcagcccccgccgcccgggccgctgtcgcagcacccgccggtgccccccgcc gccgctgggccgctcgcggggcagccgcgcaagagcagctcgtcccgccgcaacgcgtgg ggcaacctgtcctacgccgacctcatcaccaaggccatcgagagctcggcggagaagcgg ctcacgctgtcgcagatctacgagtggatggtcaagagcgtgccctacttcaaggataag ggtgacagcaacagctcggcgggctggaagaattcaattcgtcataatctgtccctacac agcaagttcattcgtgtgcagaatgaaggaactggaaaaagttcttggtggatgctcaat ccagagggtggcaagagcgggaaatctcctaggagaagagctgcatccatggacaacaac agtaaatttgctaagagccgaagccgagctgccaagaagaaagcatctctccagtctggc caggagggtgctggggacagccctggatcacagttttccaaatggcctgcaagccctggc tctcacagcaatgatgactttgataactggagtacatttcgccctcgaactagctcaaat gctagtactattagtgggagactctcacccattatgaccgaacaggatgatcttggagaa ggggatgtgcattctatggtgtacccgccatctgccgcaaagatggcctctactttaccc agtctgtctgagataagcaatcccgaaaacatggaaaatcttttggataatctcaacctt ctctcatcaccaacatcattaactgtttcgacccagtcctcacctggcaccatgatgcag cagacgccgtgctactcgtttgcgccaccaaacaccagtttgaattcacccagcccaaac taccaaaaatatacatatggccaatccagcatgagccctttgccccagatgcctatacaa acacttcaggacaataagtcgagttatggaggtatgagtcagtataactgtgcgcctgga ctcttgaaggagttgctgacttctgactctcctccccataatgacattatgacaccagtt gatcctggggtagcccagcccaacagccgggttctgggccagaacgtcatgatgggccct aattcggtcatgtcaacctatggcagccaggcatctcataacaaaatgatgaatcccagc tcccatacccaccctggacatgctcagcagacatctgcagttaacgggcgtcccctgccc cacacggtaagcaccatgccccacacctcgggtatgaaccgcctgacccaagtgaagaca cctgtacaagtgcctctgccccaccccatgcagatgagtgccctggggggctactcctcc gtgagcagctgcaatggctatggcagaatgggccttctccaccaggagaagctcccaagt gacttggatggcatgttcattgagcgcttagactgtgacatggaatccatcattcggaat gacctcatggatggagatacattggattttaactttgacaatgtgttgcccaaccaaagc ttcccacacagtgtcaagacaacgacacatagctgggtgtcaggctga

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