KEGG   Homo sapiens (human): 51060
Entry
51060             CDS       T01001                                 
Symbol
TXNDC12, AG1, AGR1, ERP16, ERP18, ERP19, PDIA16, TLP19, hAG-1, hTLP19
Name
(RefSeq) thioredoxin domain containing 12
  KO
K05360  protein-disulfide reductase (glutathione) [EC:1.8.4.2]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00480  Glutathione metabolism
hsa01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    51060 (TXNDC12)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    51060 (TXNDC12)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.8  Acting on a sulfur group of donors
   1.8.4  With a disulfide as acceptor
    1.8.4.2  protein-disulfide reductase (glutathione)
     51060 (TXNDC12)
Membrane trafficking [BR:hsa04131]
 Endoplasmic reticulum (ER) - Golgi transport
  Forward pathways
   PDI family proteins
    51060 (TXNDC12)
SSDB
Motif
Pfam: Thioredoxin_7 Thioredoxin Thioredoxin_2 Thioredox_DsbH Thioredoxin_8 AhpC-TSA Thioredoxin_9
Other DBs
NCBI-GeneID: 51060
NCBI-ProteinID: NP_056997
OMIM: 609448
HGNC: 24626
Ensembl: ENSG00000117862
UniProt: O95881
Structure
LinkDB
Position
1:complement(52020131..52056171)
AA seq 172 aa
METRPRLGATCLLGFSFLLLVISSDGHNGLGKGFGDHIHWRTLEDGKKEAAASGLPLMVI
IHKSWCGACKALKPKFAESTEISELSHNFVMVNLEDEEEPKDEDFSPDGGYIPRILFLDP
SGKVHPEIINENGNPSYKYFYVSAEQVVQGMKEAQERLTGDAFRKKHLEDEL
NT seq 519 nt   +upstreamnt  +downstreamnt
atggagacgcggcctcgtctcggggccacctgtttgctgggcttcagtttcctgctcctc
gtcatctcttctgatggacataatgggcttggaaagggttttggagatcatattcattgg
aggacactggaagatgggaagaaagaagcagctgccagtggactgcccctgatggtgatt
attcataaatcctggtgtggagcttgcaaagctctaaagcccaaatttgcagaatctacg
gaaatttcagaactctcccataattttgttatggtaaatcttgaggatgaagaggaaccc
aaagatgaagatttcagccctgacgggggttatattccacgaatcctttttctggatccc
agtggcaaggtgcatcctgaaatcatcaatgagaatggaaaccccagctacaagtatttt
tatgtcagtgccgagcaagttgttcaggggatgaaggaagctcaggaaaggctgacgggt
gatgccttcagaaagaaacatcttgaagatgaattgtaa

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