Homo sapiens (human): 51067
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Entry
51067 CDS
T01001
Symbol
YARS2, CGI-04, MLASA2, MT-TYRRS, TYRRS
Name
(RefSeq) tyrosine--tRNA ligase, mitochondrial precursor
KO
K01866
tyrosyl-tRNA synthetase [EC:
6.1.1.1
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00970
Aminoacyl-tRNA biosynthesis
Disease
H00898
Myopathy with lactic acidosis and sideroblastic anaemia
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09122 Translation
00970 Aminoacyl-tRNA biosynthesis
51067 (YARS2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01007 Amino acid related enzymes [BR:
hsa01007
]
51067 (YARS2)
09182 Protein families: genetic information processing
03016 Transfer RNA biogenesis [BR:
hsa03016
]
51067 (YARS2)
03029 Mitochondrial biogenesis [BR:
hsa03029
]
51067 (YARS2)
Enzymes [BR:
hsa01000
]
6. Ligases
6.1 Forming carbon-oxygen bonds
6.1.1 Ligases forming aminoacyl-tRNA and related compounds
6.1.1.1 tyrosine---tRNA ligase
51067 (YARS2)
Amino acid related enzymes [BR:
hsa01007
]
Aminoacyl-tRNA synthetase
Class I (A)
51067 (YARS2)
Transfer RNA biogenesis [BR:
hsa03016
]
Eukaryotic type
Aminoacyl-tRNA synthetases (AARSs)
Other AARSs
51067 (YARS2)
Prokaryotic type
51067 (YARS2)
Mitochondrial biogenesis [BR:
hsa03029
]
Mitochondrial DNA transcription, translation, and replication factors
Mitochondrial transcription and translation factors
Other mitochondrial DNA transcription and translation factors
51067 (YARS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
tRNA-synt_1b
SYY_C-terminal
S4
Motif
Other DBs
NCBI-GeneID:
51067
NCBI-ProteinID:
NP_001035526
OMIM:
610957
HGNC:
24249
Ensembl:
ENSP00000320658.8
UniProt:
Q9Y2Z4
Structure
PDB
PDBj
LinkDB
All DBs
Position
12:complement(32746544..32755897)
Genome browser
AA seq
477 aa
AA seq
DB search
MAAPILRSFSWGRWSGTLNLSVLLPLGLRKAHSGAQGLLAAQKARGLFKDFFPETGTKIE
LPELFDRGTASFPQTIYCGFDPTADSLHVGHLLALLGLFHLQRAGHNVIALVGGATARLG
DPSGRTKEREALETERVRANARALRLGLEALAANHQQLFTDGRSWGSFTVLDNSAWYQKQ
HLVDFLAAVGGHFRMGTLLSRQSVQLRLKSPEGMSLAEFFYQVLQAYDFYYLFQRYGCRV
QLGGSDQLGNIMSGYEFINKLTGEDVFGITVPLITSTTGAKLGKSAGNAVWLNRDKTSPF
ELYQFFVRQPDDSVERYLKLFTFLPLPEIDHIMQLHVKEPERRGPQKRLAAEVTKLVHGR
EGLDSAKRCTQALYHSSIDALEVMSDQELKELFKEAPFSEFFLDPGTSVLDTCRKANAIP
DGPRGYRMITEGGVSINHQQVTNPESVLIVGQHILKNGLSLLKIGKRNFYIIKWLQL
NT seq
1434 nt
NT seq
+upstream
nt +downstream
nt
atggcggcgcccatcttgcggtccttttcctggggccggtggtctggtaccctaaatctc
tcagtattgttgcccttggggctgcgtaaggcccactcgggcgctcaggggttactggca
gcgcagaaggctcgaggtctgttcaaggacttcttcccggagacggggacgaaaatagag
ctcccagagctcttcgaccgtggcacggcgagttttccccaaaccatttactgtggcttc
gaccccacggcagactcgcttcatgtgggtcatctacttgcgctgctgggcctgtttcat
ttgcagcgagcgggccacaacgtgatcgcgctggtgggaggcgccacggcgcgcctggga
gacccgagcggccgtaccaaggaacgcgaggcgctggagacagagcgcgtgcgagccaac
gcgcgagctctgcgcctagggcttgaggccctggcggctaatcaccagcagcttttcact
gatgggcgctcctggggcagcttcactgtgctggacaactcggcctggtaccagaagcag
cacctggtggacttcctggcggcagtggggggtcacttccgcatggggacgctgctgagc
cggcagagcgtgcagctgcggctcaagagccccgagggcatgagcttggccgagttcttt
taccaggtgctccaggcctatgacttctattacctcttccagcgttatggatgcagggtc
cagctgggcggatctgatcaactaggcaacatcatgtccggatatgagttcatcaacaag
ttgactggagaagatgtatttggaatcaccgttcctctaattacaagtacaactggagca
aagctgggaaagtctgctggcaacgctgtttggctaaacagagataagacatctccattt
gaattgtatcaattctttgtcaggcaaccggacgattcagtggaaaggtacctgaagctg
ttcactttcctgccccttccagagattgatcatatcatgcagctgcatgtcaaagagcca
gaaaggcggggtcctcagaaacgactggcagcagaagtaacaaagcttgttcatggacga
gaaggattggattctgctaaaaggtgtacacaagccctttatcacagtagcatagatgca
ctggaggtcatgtctgatcaggagttaaaagagttgtttaaagaagctccattttctgaa
ttttttctcgatcctggaacaagtgtcctagatacttgccgcaaagcaaatgccattcca
gatggtccccgagggtatcgaatgataacagaaggcggagtcagcataaatcaccaacaa
gtaacaaatcctgagagtgttttaattgttggacaacatattctcaagaatggactttcc
ttacttaaaataggaaaaagaaatttctacattataaaatggcttcagttgtga
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