KEGG   Homo sapiens (human): 51343
Entry
51343             CDS       T01001                                 
Symbol
FZR1, CDC20C, CDH1, DEE109, FZR, FZR2, HCDH, HCDH1
Name
(RefSeq) fizzy and cell division cycle 20 related 1
  KO
K03364  cell division cycle 20-like protein 1, cofactor of APC complex
Organism
hsa  Homo sapiens (human)
Pathway
hsa04110  Cell cycle
hsa04120  Ubiquitin mediated proteolysis
hsa04914  Progesterone-mediated oocyte maturation
Disease
H00606  Early infantile epileptic encephalopathy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    51343 (FZR1)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    51343 (FZR1)
 09150 Organismal Systems
  09152 Endocrine system
   04914 Progesterone-mediated oocyte maturation
    51343 (FZR1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    51343 (FZR1)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   APC/C
    Target recognizing subunit
     51343 (FZR1)
SSDB
Motif
Pfam: WD40_CDC20-Fz WD40 WD40_Prp19 WD40_WDHD1_1st Beta-prop_EML_2 Beta-prop_CAF1B_HIR1 Beta-prop_TEP1_2nd Beta-prop_EML Beta-prop_WDR19_1st EIF3I ANAPC4_WD40 WD40_MABP1-WDR62_2nd Beta-prop_IFT140_1st WDR55 Beta-prop_WDR90_POC16_2nd WD40_MABP1-WDR62_1st Beta-prop_RIG_2nd Beta-prop_HPS5 Beta-prop_IFT122_1st eIF2A Beta-prop_WDR35_TULP_N WDR90_beta-prop_4th Beta-prop_DCAF12 NBCH_WD40 Beta-prop_RIG_1st Beta-prop_Vps41 Beta-prop_SCAP Ge1_WD40 Beta-prop_SPT8 ELYS-bb
Other DBs
NCBI-GeneID: 51343
NCBI-ProteinID: NP_001129670
OMIM: 603619
HGNC: 24824
Ensembl: ENSG00000105325
UniProt: Q9UM11
Structure
LinkDB
Position
19:3506311..3538334
AA seq 496 aa
MDQDYERRLLRQIVIQNENTMPRVTEMRRTLTPASSPVSSPSKHGDRFIPSRAGANWSVN
FHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPS
TPEKKGLFTYSLSTKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLD
APELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSER
GNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRT
PPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKA
IAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGY
SQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTK
VKWESVSVLNLFTRIR
NT seq 1491 nt   +upstreamnt  +downstreamnt
atggaccaggactatgagcggcgcctgcttcgccagatcgtcatccagaatgagaacacg
atgccacgcgtcacagagatgcggcggaccctgacgcctgccagctccccagtgtcctcg
cccagcaagcacggagaccgcttcatcccctccagagccggagccaactggagcgtgaac
ttccacaggattaacgagaatgagaagtctcccagtcagaaccggaaagccaaggacgcc
acctcagacaacggcaaagacggcctggcctactctgccctgctcaagaatgagctgctg
ggtgccggcatcgagaaggtgcaggacccgcagactgaggaccgcaggctgcagccctcc
acgcctgagaagaagggtctgttcacgtattcccttagcaccaagcgctccagccccgat
gacggcaacgatgtgtctccctactccctgtctcccgtcagcaacaagagccagaagctg
ctccggtccccccggaaacccacccgcaagatctccaagatccccttcaaggtgctggac
gcgcccgagctgcaggacgacttctacctcaatctggtggactggtcgtccctcaatgtg
ctcagcgtggggctaggcacctgcgtgtacctgtggagtgcctgtaccagccaggtgacg
cggctctgtgacctctcagtggaaggggactcagtgacctccgtgggctggtctgagcgg
gggaacctggtggcggtgggcacacacaagggcttcgtgcagatctgggacgcagccgca
gggaagaagctgtccatgttggagggccacacggcacgcgtcggggcgctggcctggaat
gctgagcagctgtcgtccgggagccgcgaccgcatgatcctgcagagggacatccgcacc
ccgccactgcagtcggagcggcggctgcagggccaccggcaggaggtgtgcgggctcaag
tggtccacagaccaccagctcctcgcctcggggggcaacgacaacaagctgctggtctgg
aatcactcgagcctgagccccgtgcagcagtacacggagcacctggcggccgtgaaggcc
atcgcctggtccccacatcagcacgggctgctggcctcggggggcggcacagctgaccgc
tgtatccgcttctggaacacgctgacaggacaaccactgcagtgtatcgacacgggctcc
caagtgtgcaatctggcctggtccaagcacgccaacgagctggtgagcacgcacggctac
tcacagaaccagatccttgtctggaagtacccctccctgacccaggtggccaagctgacc
gggcactcctaccgcgtgctgtacctggcaatgtcccctgatggggaggccatcgtcact
ggtgctggagacgagaccctgaggttctggaacgtctttagcaaaacccgttcgacaaag
gtaaagtgggagtctgtgtctgtgctcaacctcttcaccaggatccggtaa

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