Homo sapiens (human): 5168
Help
Entry
5168 CDS
T01001
Symbol
ENPP2, ATX, ATX-X, AUTOTAXIN, LysoPLD, NPP2, PD-IALPHA, PDNP2
Name
(RefSeq) ectonucleotide pyrophosphatase/phosphodiesterase 2
KO
K01122
ectonucleotide pyrophosphatase/phosphodiesterase family member 2 [EC:
3.1.4.39
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00565
Ether lipid metabolism
hsa01100
Metabolic pathways
Drug target
Ziritaxestat:
D11844
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09103 Lipid metabolism
00565 Ether lipid metabolism
5168 (ENPP2)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.39 alkylglycerophosphoethanolamine phosphodiesterase
5168 (ENPP2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Phosphodiest
Somatomedin_B
Endonuclease_NS
Sulfatase
Motif
Other DBs
NCBI-GeneID:
5168
NCBI-ProteinID:
NP_001035181
OMIM:
601060
HGNC:
3357
Ensembl:
ENSG00000136960
UniProt:
Q13822
Structure
PDB
PDBj
LinkDB
All DBs
Position
8:complement(119557086..119673390)
Genome browser
AA seq
863 aa
AA seq
DB search
MARRSSFQSCQIISLFTFAVGVNICLGFTAHRIKRAEGWEEGPPTVLSDSPWTNISGSCK
GRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHC
SEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMK
KGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDA
TFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHER
PSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDH
GMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQH
FKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNK
VNSMQTVFVGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTF
RPTMPEEVTRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLDELNKRLHTKGSTEERHLLYG
RPAVLYRTRYDILYHTDFESGYSEIFLMPLWTSYTVSKQAEVSSVPDHLTSCVRPDVRVS
PSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWNYFQRVL
VKKYASERNGVNVISGPIFDYDYDGLHDTEDKIKQYVEGSSIPVPTHYYSIITSCLDFTQ
PADKCDGPLSVSSFILPHRPDNEESCNSSEDESKWVEELMKMHTARVRDIEHLTSLDFFR
KTSRSYPEILTLKTYLHTYESEI
NT seq
2592 nt
NT seq
+upstream
nt +downstream
nt
atggcaaggaggagctcgttccagtcgtgtcagataatatccctgttcacttttgccgtt
ggagtcaatatctgcttaggattcactgcacatcgaattaagagagcagaaggatgggag
gaaggtcctcctacagtgctatcagactccccctggaccaacatctccggatcttgcaag
ggcaggtgctttgaacttcaagaggctggacctcctgattgtcgctgtgacaacttgtgt
aagagctataccagttgctgccatgactttgatgagctgtgtttgaagacagcccgtggc
tgggagtgtactaaggacagatgtggagaagtcagaaatgaagaaaatgcctgtcactgc
tcagaggactgcttggccaggggagactgctgtaccaattaccaagtggtttgcaaagga
gagtcgcattgggttgatgatgactgtgaggaaataaaggccgcagaatgccctgcaggg
tttgttcgccctccattaatcatcttctccgtggatggcttccgtgcatcatacatgaag
aaaggcagcaaagtcatgcctaatattgaaaaactaaggtcttgtggcacacactctccc
tacatgaggccggtgtacccaactaaaacctttcctaacttatacactttggccactggg
ctatatccagaatcacatggaattgttggcaattcaatgtatgatcctgtatttgatgcc
acttttcatctgcgagggcgagagaaatttaatcatagatggtggggaggtcaaccgcta
tggattacagccaccaagcaaggggtgaaagctggaacattcttttggtctgttgtcatc
cctcacgagcggagaatattaaccatattgcagtggctcaccctgccagatcatgagagg
ccttcggtctatgccttctattctgagcaacctgatttctctggacacaaatatggccct
ttcggccctgagatgacaaatcctctgagggaaatcgacaaaattgtggggcaattaatg
gatggactgaaacaactaaaactgcatcggtgtgtcaacgtcatctttgtcggagaccat
ggaatggaagatgtcacatgtgatagaactgagttcttgagtaattacctaactaatgtg
gatgatattactttagtgcctggaactctaggaagaattcgatccaaatttagcaacaat
gctaaatatgaccccaaagccattattgccaatctcacgtgtaaaaaaccagatcagcac
tttaagccttacttgaaacagcaccttcccaaacgtttgcactatgccaacaacagaaga
attgaggatatccatttattggtggaacgcagatggcatgttgcaaggaaacctttggat
gtttataagaaaccatcaggaaaatgctttttccagggagaccacggatttgataacaag
gtcaacagcatgcagactgtttttgtaggttatggctcaacatttaagtacaagactaaa
gtgcctccatttgaaaacattgaactttacaatgttatgtgtgatctcctgggattgaag
ccagctcctaataatgggacccatggaagtttgaatcatctcctgcgcactaataccttc
aggccaaccatgccagaggaagttaccagacccaattatccagggattatgtaccttcag
tctgattttgacctgggctgcacttgtgatgataaggtagagccaaagaacaagttggat
gaactcaacaaacggcttcatacaaaagggtctacagaagagagacacctcctctatggg
cgacctgcagtgctttatcggactagatatgatatcttatatcacactgactttgaaagt
ggttatagtgaaatattcctaatgccactctggacatcatatactgtttccaaacaggct
gaggtttccagcgttcctgaccatctgaccagttgcgtccggcctgatgtccgtgtttct
ccgagtttcagtcagaactgtttggcctacaaaaatgataagcagatgtcctacggattc
ctctttcctccttatctgagctcttcaccagaggctaaatatgatgcattccttgtaacc
aatatggttccaatgtatcctgctttcaaacgggtctggaattatttccaaagggtattg
gtgaagaaatatgcttcggaaagaaatggagttaacgtgataagtggaccaatcttcgac
tatgactatgatggcttacatgacacagaagacaaaataaaacagtacgtggaaggcagt
tccattcctgttccaactcactactacagcatcatcaccagctgtctggatttcactcag
cctgccgacaagtgtgacggccctctctctgtgtcctccttcatcctgcctcaccggcct
gacaacgaggagagctgcaatagctcagaggacgaatcaaaatgggtagaagaactcatg
aagatgcacacagctagggtgcgtgacattgaacatctcaccagcctggacttcttccga
aagaccagccgcagctacccagaaatcctgacactcaagacatacctgcatacatatgag
agcgagatttaa
DBGET
integrated database retrieval system
