Homo sapiens (human): 51692
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Entry
51692 CDS
T01001
Symbol
CPSF3, CPSF-73, CPSF73, NEDMHS, NEDMHSN
Name
(RefSeq) cleavage and polyadenylation specific factor 3
KO
K14403
cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
Organism
hsa
Homo sapiens (human)
Pathway
hsa03015
mRNA surveillance pathway
Disease
H02461
Neurodevelopmental disorder with microcephaly
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09122 Translation
03015 mRNA surveillance pathway
51692 (CPSF3)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
hsa03021
]
51692 (CPSF3)
03019 Messenger RNA biogenesis [BR:
hsa03019
]
51692 (CPSF3)
Transcription machinery [BR:
hsa03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
51692 (CPSF3)
Messenger RNA biogenesis [BR:
hsa03019
]
Eukaryotic type
mRNA processing factors
3' end processing
Cleavage and polyadenylation specificity factor (CPSF) complex
51692 (CPSF3)
U7-dependent histone pre-mRNA processing factors
51692 (CPSF3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
CPSF73-100_C
Beta-Casp
Lactamase_B_6
Lactamase_B
RMMBL
Lactamase_B_2
Lactamase_B_3
Beta_lactamase3
Motif
Other DBs
NCBI-GeneID:
51692
NCBI-ProteinID:
NP_057291
OMIM:
606029
HGNC:
2326
Ensembl:
ENSG00000119203
UniProt:
Q9UKF6
Structure
PDB
PDBj
LinkDB
All DBs
Position
2:9423654..9473101
Genome browser
AA seq
684 aa
AA seq
DB search
MSAIPAEESDQLLIRPLGAGQEVGRSCIILEFKGRKIMLDCGIHPGLEGMDALPYIDLID
PAEIDLLLISHFHLDHCGALPWFLQKTSFKGRTFMTHATKAIYRWLLSDYVKVSNISADD
MLYTETDLEESMDKIETINFHEVKEVAGIKFWCYHAGHVLGAAMFMIEIAGVKLLYTGDF
SRQEDRHLMAAEIPNIKPDILIIESTYGTHIHEKREEREARFCNTVHDIVNRGGRGLIPV
FALGRAQELLLILDEYWQNHPELHDIPIYYASSLAKKCMAVYQTYVNAMNDKIRKQININ
NPFVFKHISNLKSMDHFDDIGPSVVMASPGMMQSGLSRELFESWCTDKRNGVIIAGYCVE
GTLAKHIMSEPEEITTMSGQKLPLKMSVDYISFSAHTDYQQTSEFIRALKPPHVILVHGE
QNEMARLKAALIREYEDNDEVHIEVHNPRNTEAVTLNFRGEKLAKVMGFLADKKPEQGQR
VSGILVKRNFNYHILSPCDLSNYTDLAMSTVKQTQAIPYTGPFNLLCYQLQKLTGDVEEL
EIQEKPALKVFKNITVIQEPGMVVLEWLANPSNDMYADTVTTVILEVQSNPKIRKGAVQK
VSKKLEMHVYSKRLEIMLQDIFGEDCVSVKDDSILSVTVDGKTANLNLETRTVECEEGSE
DDESLREMVELAAQRLYEALTPVH
NT seq
2055 nt
NT seq
+upstream
nt +downstream
nt
atgtctgcgattcctgctgaggagagcgaccagctgctgatccgaccccttggagctggg
caagaagtaggaagatcatgtattattctcgagttcaaaggaagaaaaataatgctcgac
tgtgggatccaccctggcctagaaggaatggatgctcttccttatattgatttaattgac
ccagctgagattgatctcctattaattagtcatttccatttggatcactgtggagctctg
ccctggtttctacagaagacaagtttcaaaggaagaacatttatgactcatgccacaaaa
gctatttatagatggcttctttctgattatgtcaaagttagtaacatatcagcagacgac
atgctgtataccgagacagatttggaagaaagcatggacaaaattgaaactatcaacttt
catgaagttaaggaagttgcgggaatcaagttttggtgttaccatgcaggtcacgtccta
ggagccgccatgttcatgattgagatcgcaggcgtgaagcttttgtacactggtgatttc
tcaagacaagaagataggcacttaatggcagctgaaattcctaatattaagcctgatatt
cttatcattgaatctacttatgggacccatatccatgagaaacgtgaagagcgagaagca
agattctgtaacactgtccacgatattgtaaacagaggaggcaggggtctcattcctgtc
tttgctcttggaagggctcaggagctgctcttgattctagatgagtactggcagaatcac
ccagaactacatgacattccaatatactatgcatcatctttggccaagaagtgtatggca
gtgtaccagacatatgtaaatgccatgaatgacaaaatccgcaaacagatcaacatcaat
aatccctttgttttcaaacacattagtaacctcaagagcatggatcattttgatgacatt
ggtcccagtgttgtaatggcctccccaggcatgatgcaaagtggcttatccagagaatta
tttgaaagctggtgtactgataagaggaatggtgtcattatagcgggatactgtgtagaa
gggacacttgccaagcacatcatgtctgaacctgaagaaatcactactatgtctggacag
aagttaccactgaaaatgtctgttgattacatttctttctcagctcacacggattaccag
caaaccagtgaatttattcgtgctttgaaaccgcctcatgtgattttagtccatggagaa
cagaatgaaatggccagattgaaagcagcactgattcgagaatatgaagataacgatgaa
gttcacatagaggttcataatcctcggaatacagaagcagtgaccttaaacttcagagga
gaaaaactagccaaggttatgggatttttagcagacaaaaaaccagaacaaggccagcgg
gtctcaggaatacttgttaaaagaaactttaattatcacatactttctccttgcgacctg
tccaattatactgacctggccatgagcacggtgaagcagacccaagccattccatatact
ggtccctttaatttgctctgttaccagctgcagaaattgacaggtgatgtggaagaatta
gaaattcaagaaaaacctgctctgaaagtgttcaaaaatattactgtaatacaagaacca
ggcatggtggtattagaatggctggcaaacccttctaatgatatgtatgcagatacagta
acaactgtgatattggaagttcagtcaaatcccaaaataagaaaaggtgcagtacagaag
gtttctaaaaaattagaaatgcacgtttacagcaagaggttggagatcatgctccaggac
atatttggagaagactgtgtaagtgtaaaggatgactctattcttagcgtcacagtggac
gggaaaactgccaaccttaacttggagacacggactgtagaatgtgaagagggaagtgaa
gacgatgaatccctccgagaaatggtggagctggctgcacagagactgtacgaggccctg
acgccagttcactga
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