Homo sapiens (human): 5226 Help Entry 5226              CDS       T01001                                  Symbol PGD, 6PGD Name (RefSeq) phosphogluconate dehydrogenase   KO K00033   6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343] Organism hsa  Homo sapiens (human) Pathway hsa00030   Pentose phosphate pathway hsa00480   Glutathione metabolism hsa01100   Metabolic pathways hsa01200   Carbon metabolism Module hsa_M00004   Pentose phosphate pathway (Pentose phosphate cycle) hsa_M00006   Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P Network nt06026  Glutathione biosynthesis   Element N00905   NADP+ reduction Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09101 Carbohydrate metabolism    00030 Pentose phosphate pathway     5226 (PGD)   09106 Metabolism of other amino acids    00480 Glutathione metabolism     5226 (PGD) Enzymes [BR:hsa01000]  1. Oxidoreductases   1.1  Acting on the CH-OH group of donors    1.1.1  With NAD+ or NADP+ as acceptor     1.1.1.44  phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating)      5226 (PGD)     1.1.1.343  phosphogluconate dehydrogenase (NAD+-dependent, decarboxylating)      5226 (PGD) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  6PGD NAD_binding_2 F420_oxidored NAD_binding_11 ApbA Motif Other DBs NCBI-GeneID:  5226 NCBI-ProteinID:  NP_002622 OMIM:  172200 HGNC:  8891 Ensembl:  ENSG00000142657 UniProt:  P52209 Structure PDBPDBj LinkDB All DBs Position 1:10399064..10420511 Genome browser AA seq 483 aa AA seqDB search MAQADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKE MVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKG ILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAG HFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANIL KFQDTDGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQA SKKLKGPQKFQFDGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIAL MWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTGVQAGIPM PCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPGQFIHTNWTGHGGTVSSSS YNA NT seq 1452 nt NT seq  +upstreamnt  +downstreamnt atggcccaagctgacatcgcgctgatcggattggccgtcatgggccagaacttaattctg aacatgaatgaccacggctttgtggtctgtgcttttaataggactgtctccaaagttgat gatttcttggccaatgaggcaaagggaaccaaagtggtgggtgcccagtccctgaaagag atggtctccaagctgaagaagccccggcggatcatcctcctggtgaaggctgggcaagct gtggatgatttcatcgagaaattggtaccattgttggatactggtgacatcatcattgac ggaggaaattctgaatatagggacaccacaagacggtgccgagacctcaaggccaaggga attttatttgtggggagcggagtcagtggtggagaggaaggggcccggtatggcccatcg ctcatgccaggagggaacaaagaagcgtggccccacatcaagaccatcttccaaggcatt gctgcaaaagtgggaactggagaaccctgctgtgactgggtgggagatgagggagcaggc cacttcgtgaagatggtgcacaacgggatagagtatggggacatgcagctgatctgtgag gcataccacctgatgaaagacgtgctgggcatggcgcaggacgagatggcccaggccttt gaggattggaataagacagagctagactcattcctgattgaaatcacagccaatattctc aagttccaagacaccgatggcaaacacctgctgccaaagatcagggacagcgcggggcag aagggcacagggaagtggaccgccatctccgccctggaatacggcgtacccgtcaccctc attggagaagctgtctttgctcggtgcttatcatctctgaaggatgagagaattcaagct agcaaaaagctgaagggtccccagaagttccagtttgatggtgataagaaatcattcctg gaggacattcggaaggcactctacgcttccaagatcatctcttacgctcaaggctttatg ctgctaaggcaggcagccaccgagtttggctggactctcaattatggtggcatcgccctg atgtggagagggggctgcatcattagaagtgtattcctaggaaagataaaggatgcattt gatcgaaacccggaacttcagaacctcctactggacgacttctttaagtcagctgttgaa aactgccaggactcctggcggcgggcagtcagcactggggtccaggctggcattcccatg ccctgttttaccactgccctctccttctatgacgggtacagacatgagatgcttccagcc agcctcatccaggctcagcgggattacttcggggctcacacctatgaactcttggccaaa ccagggcagtttatccacaccaactggacaggccatggtggcaccgtgtcatcctcgtca tacaatgcctga

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