Homo sapiens (human): 5310
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Entry
5310 CDS
T01001
Symbol
PKD1, PBP, PC1, Pc-1, TRPP1
Name
(RefSeq) polycystin 1, transient receptor potential channel interacting
KO
K04985
polycystin 1
Organism
hsa
Homo sapiens (human)
Disease
H00542
Polycystic kidney disease
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
03037 Cilium and associated proteins [BR:
hsa03037
]
5310 (PKD1)
04812 Cytoskeleton proteins [BR:
hsa04812
]
5310 (PKD1)
04040 Ion channels [BR:
hsa04040
]
5310 (PKD1)
04091 Lectins [BR:
hsa04091
]
5310 (PKD1)
Cilium and associated proteins [BR:
hsa03037
]
Primary cilia and associated proteins
Other primary cilia associated proteins
5310 (PKD1)
Cytoskeleton proteins [BR:
hsa04812
]
Eukaryotic cytoskeleton proteins
Intermediate filaments
Intermediate filament-binding proteins
5310 (PKD1)
Ion channels [BR:
hsa04040
]
Voltage-gated cation channels
Transient receptor potential channel (TRP)
5310 (PKD1)
Lectins [BR:
hsa04091
]
C-Type lectins
Group 10: Polycystin
5310 (PKD1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PKD
REJ
PKD_4
Polycystin_dom
PKD_channel
PLAT
LRR_8
WSC
Lectin_C
LRRNT
LRRCT
LRR_4
Motif
Other DBs
NCBI-GeneID:
5310
NCBI-ProteinID:
NP_001009944
OMIM:
601313
HGNC:
9008
Ensembl:
ENSG00000008710
UniProt:
P98161
Structure
PDB
LinkDB
All DBs
Position
16:complement(2088708..2135898)
Genome browser
AA seq
4303 aa
AA seq
DB search
MPPAAPARLALALGLGLWLGALAGGPGRGCGPCEPPCLCGPAPGAACRVNCSGRGLRTLG
PALRIPADATALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEI
NLSGNPFECDCGLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLLDSGCGEEY
VACLPDNSSGTVAAVSFSAAHEGLLQPEACSAFCFSTGQGLAALSEQGWCLCGAAQPSSA
SFACLSLCSGPPPPPAPTCRGPTLLQHVFPASPGATLVGPHGPLASGQLAAFHIAAPLPV
TATRWDFGDGSAEVDAAGPAASHRYVLPGRYHVTAVLALGAGSALLGTDVQVEAAPAALE
LVCPSSVQSDESLDLSIQNRGGSGLEAAYSIVALGEEPARAVHPLCPSDTEIFPGNGHCY
RLVVEKAAWLQAQEQCQAWAGAALAMVDSPAVQRFLVSRVTRSLDVWIGFSTVQGVEVGP
APQGEAFSLESCQNWLPGEPHPATAEHCVRLGPTGWCNTDLCSAPHSYVCELQPGGPVQD
AENLLVGAPSGDLQGPLTPLAQQDGLSAPHEPVEVMVFPGLRLSREAFLTTAEFGTQELR
RPAQLRLQVYRLLSTAGTPENGSEPESRSPDNRTQLAPACMPGGRWCPGANICLPLDASC
HPQACANGCTSGPGLPGAPYALWREFLFSVPAGPPAQYSVTLHGQDVLMLPGDLVGLQHD
AGPGALLHCSPAPGHPGPRAPYLSANASSWLPHLPAQLEGTWACPACALRLLAATEQLTV
LLGLRPNPGLRLPGRYEVRAEVGNGVSRHNLSCSFDVVSPVAGLRVIYPAPRDGRLYVPT
NGSALVLQVDSGANATATARWPGGSVSARFENVCPALVATFVPGCPWETNDTLFSVVALP
WLSEGEHVVDVVVENSASRANLSLRVTAEEPICGLRATPSPEARVLQGVLVRYSPVVEAG
SDMVFRWTINDKQSLTFQNVVFNVIYQSAAVFKLSLTASNHVSNVTVNYNVTVERMNRMQ
GLQVSTVPAVLSPNATLALTAGVLVDSAVEVAFLWTFGDGEQALHQFQPPYNESFPVPDP
SVAQVLVEHNVMHTYAAPGEYLLTVLASNAFENLTQQVPVSVRASLPSVAVGVSDGVLVA
GRPVTFYPHPLPSPGGVLYTWDFGDGSPVLTQSQPAANHTYASRGTYHVRLEVNNTVSGA
AAQADVRVFEELRGLSVDMSLAVEQGAPVVVSAAVQTGDNITWTFDMGDGTVLSGPEATV
EHVYLRAQNCTVTVGAASPAGHLARSLHVLVFVLEVLRVEPAACIPTQPDARLTAYVTGN
PAHYLFDWTFGDGSSNTTVRGCPTVTHNFTRSGTFPLALVLSSRVNRAHYFTSICVEPEV
GNVTLQPERQFVQLGDEAWLVACAWPPFPYRYTWDFGTEEAAPTRARGPEVTFIYRDPGS
YLVTVTASNNISAANDSALVEVQEPVLVTSIKVNGSLGLELQQPYLFSAVGRGRPASYLW
DLGDGGWLEGPEVTHAYNSTGDFTVRVAGWNEVSRSEAWLNVTVKRRVRGLVVNASRTVV
PLNGSVSFSTSLEAGSDVRYSWVLCDRCTPIPGGPTISYTFRSVGTFNIIVTAENEVGSA
QDSIFVYVLQLIEGLQVVGGGRYFPTNHTVQLQAVVRDGTNVSYSWTAWRDRGPALAGSG
KGFSLTVLEAGTYHVQLRATNMLGSAWADCTMDFVEPVGWLMVAASPNPAAVNTSVTLSA
ELAGGSGVVYTWSLEEGLSWETSEPFTTHSFPTPGLHLVTMTAGNPLGSANATVEVDVQV
PVSGLSIRASEPGGSFVAAGSSVPFWGQLATGTNVSWCWAVPGGSSKRGPHVTMVFPDAG
TFSIRLNASNAVSWVSATYNLTAEEPIVGLVLWASSKVVAPGQLVHFQILLAAGSAVTFR
LQVGGANPEVLPGPRFSHSFPRVGDHVVSVRGKNHVSWAQAQVRIVVLEAVSGLQVPNCC
EPGIATGTERNFTARVQRGSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGLLEIQV
RAFNALGSENRTLVLEVQDAVQYVALQSGPCFTNRSAQFEAATSPSPRRVAYHWDFGDGS
PGQDTDEPRAEHSYLRPGDYRVQVNASNLVSFFVAQATVTVQVLACREPEVDVVLPLQVL
MRRSQRNYLEAHVDLRDCVTYQTEYRWEVYRTASCQRPGRPARVALPGVDVSRPRLVLPR
LALPVGHYCFVFVVSFGDTPLTQSIQANVTVAPERLVPIIEGGSYRVWSDTRDLVLDGSE
SYDPNLEDGDQTPLSFHWACVASTQREAGGCALNFGPRGSSTVTIPRERLAAGVEYTFSL
TVWKAGRKEEATNQTVLIRSGRVPIVSLECVSCKAQAVYEVSRSSYVYLEGRCLNCSSGS
KRGRWAARTFSNKTLVLDETTTSTGSAGMRLVLRRGVLRDGEGYTFTLTVLGRSGEEEGC
ASIRLSPNRPPLGGSCRLFPLGAVHALTTKVHFECTGWHDAEDAGAPLVYALLLRRCRQG
HCEEFCVYKGSLSSYGAVLPPGFRPHFEVGLAVVVQDQLGAAVVALNRSLAITLPEPNGS
ATGLTVWLHGLTASVLPGLLRQADPQHVIEYSLALVTVLNEYERALDVAAEPKHERQHRA
QIRKNITETLVSLRVHTVDDIQQIAAALAQCMGPSRELVCRSCLKQTLHKLEAMMLILQA
ETTAGTVTPTAIGDSILNITGDLIHLASSDVRAPQPSELGAESPSRMVASQAYNLTSALM
RILMRSRVLNEEPLTLAGEEIVAQGKRSDPRSLLCYGGAPGPGCHFSIPEAFSGALANLS
DVVQLIFLVDSNPFPFGYISNYTVSTKVASMAFQTQAGAQIPIERLASERAITVKVPNNS
DWAARGHRSSANSANSVVVQPQASVGAVVTLDSSNPAAGLHLQLNYTLLDGHYLSEEPEP
YLAVYLHSEPRPNEHNCSASRRIRPESLQGADHRPYTFFISPGSRDPAGSYHLNLSSHFR
WSALQVSVGLYTSLCQYFSEEDMVWRTEGLLPLEETSPRQAVCLTRHLTAFGASLFVPPS
HVRFVFPEPTADVNYIVMLTCAVCLVTYMVMAAILHKLDQLDASRGRAIPFCGQRGRFKY
EILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDRAFHRNSLDIFRIATPHSLGSVW
KIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDA
ALLRFRRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYG
AVGDSAYSTGHVSRLSPLSVDTVAVGLVSSVVVYPVYLAILFLFRMSRSKVAGSPSPTPA
GQQVLDIDSCLDSSVLDSSFLTFSGLHAEQAFVGQMKSDLFLDDSKSLVCWPSGEGTLSW
PDLLSDPSIVGSNLRQLARGQAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEG
VSSPAPTQDTHMETDLLSSLSSTPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTG
LVEGLRKRLLPAWCASLAHGLSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASF
LGWEPLKVLLEALYFSLVAKRLHPDEDDTLVESPAVTPVSARVPRVRPPHGFALFLAKEE
ARKVKRLHGMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRS
EELWPWMAHVLLPYVHGNQSSPELGPPRLRQVRLQEALYPDPPGPRVHTCSAAGGFSTSD
YDVGWESPHNGSGTWAYSAPDLLGAWSWGSCAVYDSGGYVQELGLSLEESRDRLRFLQLH
NWLDNRSRAVFLELTRYSPAVGLHAAVTLRLEFPAAGRALAALSVRPFALRRLSAGLSLP
LLTSVCLLLFAVHFAVAEARTWHREGRWRVLRLGAWARWLLVALTAATALVRLAQLGAAD
RQWTRFVRGRPRRFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLC
RALPELLGVTLGLVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGTGLSTLCPAESW
HLSPLLCVGLWALRLWGALRLGAVILRWRYHALRGELYRPAWEPQDYEMVELFLRRLRLW
MGLSKVKEFRHKVRFEGMEPLPSRSSRGSKVSPDVPPPSAGSDASHPSTSSSQLDGLSVS
LGRLGTRCEPEPSRLQAVFEALLTQFDRLNQATEDVYQLEQQLHSLQGRRSSRAPAGSSR
GPSPGLRPALPSRLARASRGVDLATGPSRTPLRAKNKVHPSST
NT seq
12912 nt
NT seq
+upstream
nt +downstream
nt
atgccgcccgccgcgcccgcccgcctggcgctggccctgggcctgggcctgtggctcggg
gcgctggcggggggccccgggcgcggctgcgggccctgcgagcccccctgcctctgcggc
ccagcgcccggcgccgcctgccgcgtcaactgctcgggccgcgggctgcggacgctcggt
cccgcgctgcgcatccccgcggacgccacagcgctagacgtctcccacaacctgctccgg
gcgctggacgttgggctcctggcgaacctctcggcgctggcagagctggatataagcaac
aacaagatttctacgttagaagaaggaatatttgctaatttatttaatttaagtgaaata
aacctgagtgggaacccgtttgagtgtgactgtggcctggcgtggctgccgcgatgggcg
gaggagcagcaggtgcgggtggtgcagcccgaggcagccacgtgtgctgggcctggctcc
ctggctggccagcctctgcttggcatccccttgctggacagtggctgtggtgaggagtat
gtcgcctgcctccctgacaacagctcaggcaccgtggcagcagtgtccttttcagctgcc
cacgaaggcctgcttcagccagaggcctgcagcgccttctgcttctccaccggccagggc
ctcgcagccctctcggagcagggctggtgcctgtgtggggcggcccagccctccagtgcc
tcctttgcctgcctgtccctctgctccggccccccgccacctcctgcccccacctgtagg
ggccccaccctcctccagcacgtcttccctgcctccccaggggccaccctggtggggccc
cacggacctctggcctctggccagctagcagccttccacatcgctgccccgctccctgtc
actgccacacgctgggacttcggagacggctccgccgaggtggatgccgctgggccggct
gcctcgcatcgctatgtgctgcctgggcgctatcacgtgacggccgtgctggccctgggg
gccggctcagccctgctggggacagacgtgcaggtggaagcggcacctgccgccctggag
ctcgtgtgcccgtcctcggtgcagagtgacgagagcctcgacctcagcatccagaaccgc
ggtggttcaggcctggaggccgcctacagcatcgtggccctgggcgaggagccggcccga
gcggtgcacccgctctgcccctcggacacggagatcttccctggcaacgggcactgctac
cgcctggtggtggagaaggcggcctggctgcaggcgcaggagcagtgtcaggcctgggcc
ggggccgccctggcaatggtggacagtcccgccgtgcagcgcttcctggtctcccgggtc
accaggagcctagacgtgtggatcggcttctcgactgtgcagggggtggaggtgggccca
gcgccgcagggcgaggccttcagcctggagagctgccagaactggctgcccggggagcca
cacccagccacagccgagcactgcgtccggctcgggcccaccgggtggtgtaacaccgac
ctgtgctcagcgccgcacagctacgtctgcgagctgcagcccggaggcccagtgcaggat
gccgagaacctcctcgtgggagcgcccagtggggacctgcagggacccctgacgcctctg
gcacagcaggacggcctctcagccccgcacgagcccgtggaggtcatggtattcccgggc
ctgcgtctgagccgtgaagccttcctcaccacggccgaatttgggacccaggagctccgg
cggcccgcccagctgcggctgcaggtgtaccggctcctcagcacagcagggaccccggag
aacggcagcgagcctgagagcaggtccccggacaacaggacccagctggcccccgcgtgc
atgccagggggacgctggtgccctggagccaacatctgcttgccgctggacgcctcctgc
cacccccaggcctgcgccaatggctgcacgtcagggccagggctacccggggccccctat
gcgctatggagagagttcctcttctccgttcccgcggggccccccgcgcagtactcggtc
accctccacggccaggatgtcctcatgctccctggtgacctcgttggcttgcagcacgac
gctggccctggcgccctcctgcactgctcgccggctcccggccaccctggtccccgggcc
ccgtacctctccgccaacgcctcgtcatggctgccccacttgccagcccagctggagggc
acttgggcctgccctgcctgtgccctgcggctgcttgcagccacggaacagctcaccgtg
ctgctgggcttgaggcccaaccctggactgcggctgcctgggcgctatgaggtccgggca
gaggtgggcaatggcgtgtccaggcacaacctctcctgcagctttgacgtggtctcccca
gtggctgggctgcgggtcatctaccctgccccccgcgacggccgcctctacgtgcccacc
aacggctcagccttggtgctccaggtggactctggtgccaacgccacggccacggctcgc
tggcctgggggcagtgtcagcgcccgctttgagaatgtctgccctgccctggtggccacc
ttcgtgcccggctgcccctgggagaccaacgataccctgttctcagtggtagcactgccg
tggctcagtgagggggagcacgtggtggacgtggtggtggaaaacagcgccagccgggcc
aacctcagcctgcgggtgacggcggaggagcccatctgtggcctccgcgccacgcccagc
cccgaggcccgtgtactgcagggagtcctagtgaggtacagccccgtggtggaggccggc
tcggacatggtcttccggtggaccatcaacgacaagcagtccctgaccttccagaacgtg
gtcttcaatgtcatttatcagagcgcggcggtcttcaagctctcactgacggcctccaac
cacgtgagcaacgtcaccgtgaactacaacgtaaccgtggagcggatgaacaggatgcag
ggtctgcaggtctccacagtgccggccgtgctgtcccccaatgccacgctagcactgacg
gcgggcgtgctggtggactcggccgtggaggtggccttcctgtggacctttggggatggg
gagcaggccctccaccagttccagcctccgtacaacgagtccttcccggttccagacccc
tcggtggcccaggtgctggtggagcacaatgtcatgcacacctacgctgccccaggtgag
tacctcctgaccgtgctggcatctaatgccttcgagaacctgacgcagcaggtgcctgtg
agcgtgcgcgcctccctgccctccgtggctgtgggtgtgagtgacggcgtcctggtggcc
ggccggcccgtcaccttctacccgcacccgctgccctcgcctgggggtgttctttacacg
tgggacttcggggacggctcccctgtcctgacccagagccagccggctgccaaccacacc
tatgcctcgaggggcacctaccacgtgcgcctggaggtcaacaacacggtgagcggtgcg
gcggcccaggcggatgtgcgcgtctttgaggagctccgcggactcagcgtggacatgagc
ctggccgtggagcagggcgcccccgtggtggtcagcgccgcggtgcagacgggcgacaac
atcacgtggaccttcgacatgggggacggcaccgtgctgtcgggcccggaggcaacagtg
gagcatgtgtacctgcgggcacagaactgcacagtgaccgtgggtgcggccagccccgcc
ggccacctggcccggagcctgcacgtgctggtcttcgtcctggaggtgctgcgcgttgaa
cccgccgcctgcatccccacgcagcctgacgcgcggctcacggcctacgtcaccgggaac
ccggcccactacctcttcgactggaccttcggggatggctcctccaacacgaccgtgcgg
gggtgcccgacggtgacacacaacttcacgcggagcggcacgttccccctggcgctggtg
ctgtccagccgcgtgaacagggcgcattacttcaccagcatctgcgtggagccagaggtg
ggcaacgtcaccctgcagccagagaggcagtttgtgcagctcggggacgaggcctggctg
gtggcatgtgcctggcccccgttcccctaccgctacacctgggactttggcaccgaggaa
gccgcccccacccgtgccaggggccctgaggtgacgttcatctaccgagacccaggctcc
tatcttgtgacagtcaccgcgtccaacaacatctctgctgccaatgactcagccctggtg
gaggtgcaggagcccgtgctggtcaccagcatcaaggtcaatggctcccttgggctggag
ctgcagcagccgtacctgttctctgctgtgggccgtgggcgccccgccagctacctgtgg
gatctgggggacggtgggtggctcgagggtccggaggtcacccacgcttacaacagcaca
ggtgacttcaccgttagggtggccggctggaatgaggtgagccgcagcgaggcctggctc
aatgtgacggtgaagcggcgcgtgcgggggctcgtcgtcaatgcaagccgcacggtggtg
cccctgaatgggagcgtgagcttcagcacgtcgctggaggccggcagtgatgtgcgctat
tcctgggtgctctgtgaccgctgcacgcccatccctgggggtcctaccatctcttacacc
ttccgctccgtgggcaccttcaatatcatcgtcacggctgagaacgaggtgggctccgcc
caggacagcatcttcgtctatgtcctgcagctcatagaggggctgcaggtggtgggcggt
ggccgctacttccccaccaaccacacggtacagctgcaggccgtggttagggatggcacc
aacgtctcctacagctggactgcctggagggacaggggcccggccctggccggcagcggc
aaaggcttctcgctcaccgtgctcgaggccggcacctaccatgtgcagctgcgggccacc
aacatgctgggcagcgcctgggccgactgcaccatggacttcgtggagcctgtggggtgg
ctgatggtggccgcctccccgaacccagctgccgtcaacacaagcgtcaccctcagtgcc
gagctggctggtggcagtggtgtcgtatacacttggtccttggaggaggggctgagctgg
gagacctccgagccatttaccacccatagcttccccacacccggcctgcacttggtcacc
atgacggcagggaacccgctgggctcagccaacgccaccgtggaagtggatgtgcaggtg
cctgtgagtggcctcagcatcagggccagcgagcccggaggcagcttcgtggcggccggg
tcctctgtgcccttttgggggcagctggccacgggcaccaatgtgagctggtgctgggct
gtgcccggcggcagcagcaagcgtggccctcatgtcaccatggtcttcccggatgctggc
accttctccatccggctcaatgcctccaacgcagtcagctgggtctcagccacgtacaac
ctcacggcggaggagcccatcgtgggcctggtgctgtgggccagcagcaaggtggtggcg
cccgggcagctggtccattttcagatcctgctggctgccggctcagctgtcaccttccgc
ctgcaggtcggcggggccaaccccgaggtgctccccgggccccgtttctcccacagcttc
ccccgcgtcggagaccacgtggtgagcgtgcggggcaaaaaccacgtgagctgggcccag
gcgcaggtgcgcatcgtggtgctggaggccgtgagtgggctgcaggtgcccaactgctgc
gagcctggcatcgccacgggcactgagaggaacttcacagcccgcgtgcagcgcggctct
cgggtcgcctacgcctggtacttctcgctgcagaaggtccagggcgactcgctggtcatc
ctgtcgggccgcgacgtcacctacacgcccgtggccgcggggctgttggagatccaggtg
cgcgccttcaacgccctgggcagtgagaaccgcacgctggtgctggaggttcaggacgcc
gtccagtatgtggccctgcagagcggcccctgcttcaccaaccgctcggcgcagtttgag
gccgccaccagccccagcccccggcgtgtggcctaccactgggactttggggatgggtcg
ccagggcaggacacagatgagcccagggccgagcactcctacctgaggcctggggactac
cgcgtgcaggtgaacgcctccaacctggtgagcttcttcgtggcgcaggccacggtgacc
gtccaggtgctggcctgccgggagccggaggtggacgtggtcctgcccctgcaggtgctg
atgcggcgatcacagcgcaactacttggaggcccacgttgacctgcgcgactgcgtcacc
taccagactgagtaccgctgggaggtgtatcgcaccgccagctgccagcggccggggcgc
ccagcgcgtgtggccctgcccggcgtggacgtgagccggcctcggctggtgctgccgcgg
ctggcgctgcctgtggggcactactgctttgtgtttgtcgtgtcatttggggacacgcca
ctgacacagagcatccaggccaatgtgacggtggcccccgagcgcctggtgcccatcatt
gagggtggctcataccgcgtgtggtcagacacacgggacctggtgctggatgggagcgag
tcctacgaccccaacctggaggacggcgaccagacgccgctcagtttccactgggcctgt
gtggcttcgacacagagggaggctggcgggtgtgcgctgaactttgggccccgcgggagc
agcacggtcaccattccacgggagcggctggcggctggcgtggagtacaccttcagcctg
accgtgtggaaggccggccgcaaggaggaggccaccaaccagacggtgctgatccggagt
ggccgggtgcccattgtgtccttggagtgtgtgtcctgcaaggcacaggccgtgtacgaa
gtgagccgcagctcctacgtgtacttggagggccgctgcctcaattgcagcagcggctcc
aagcgagggcggtgggctgcacgtacgttcagcaacaagacgctggtgctggatgagacc
accacatccacgggcagtgcaggcatgcgactggtgctgcggcggggcgtgctgcgggac
ggcgagggatacaccttcacgctcacggtgctgggccgctctggcgaggaggagggctgc
gcctccatccgcctgtcccccaaccgcccgccgctggggggctcttgccgcctcttccca
ctgggcgctgtgcacgccctcaccaccaaggtgcacttcgaatgcacgggctggcatgac
gcggaggatgctggcgccccgctggtgtacgccctgctgctgcggcgctgtcgccagggc
cactgcgaggagttctgtgtctacaagggcagcctctccagctacggagccgtgctgccc
ccgggtttcaggccacacttcgaggtgggcctggccgtggtggtgcaggaccagctggga
gccgctgtggtcgccctcaacaggtctttggccatcaccctcccagagcccaacggcagc
gcaacggggctcacagtctggctgcacgggctcaccgctagtgtgctcccagggctgctg
cggcaggccgatccccagcacgtcatcgagtactcgttggccctggtcaccgtgctgaac
gagtacgagcgggccctggacgtggcggcagagcccaagcacgagcggcagcaccgagcc
cagatacgcaagaacatcacggagactctggtgtccctgagggtccacactgtggatgac
atccagcagatcgctgctgcgctggcccagtgcatggggcccagcagggagctcgtatgc
cgctcgtgcctgaagcagacgctgcacaagctggaggccatgatgctcatcctgcaggca
gagaccaccgcgggcaccgtgacgcccaccgccatcggagacagcatcctcaacatcaca
ggagacctcatccacctggccagctcggacgtgcgggcaccacagccctcagagctggga
gccgagtcaccatctcggatggtggcgtcccaggcctacaacctgacctctgccctcatg
cgcatcctcatgcgctcccgcgtgctcaacgaggagcccctgacgctggcgggcgaggag
atcgtggcccagggcaagcgctcggacccgcggagcctgctgtgctatggcggcgcccca
gggcctggctgccacttctccatccccgaggctttcagcggggccctggccaacctcagt
gacgtggtgcagctcatctttctggtggactccaatccctttccctttggctatatcagc
aactacaccgtctccaccaaggtggcctcgatggcattccagacacaggccggcgcccag
atccccatcgagcggctggcctcagagcgcgccatcaccgtgaaggtgcccaacaactcg
gactgggctgcccggggccaccgcagctccgccaactccgccaactccgttgtggtccag
ccccaggcctccgtcggtgctgtggtcaccctggacagcagcaaccctgcggccgggctg
catctgcagctcaactatacgctgctggacggccactacctgtctgaggaacctgagccc
tacctggcagtctacctacactcggagccccggcccaatgagcacaactgctcggctagc
aggaggatccgcccagagtcactccagggtgctgaccaccggccctacaccttcttcatt
tccccggggagcagagacccagcggggagttaccatctgaacctctccagccacttccgc
tggtcggcgctgcaggtgtccgtgggcctgtacacgtccctgtgccagtacttcagcgag
gaggacatggtgtggcggacagaggggctgctgcccctggaggagacctcgccccgccag
gccgtctgcctcacccgccacctcaccgccttcggcgccagcctcttcgtgcccccaagc
catgtccgctttgtgtttcctgagccgacagcggatgtaaactacatcgtcatgctgaca
tgtgctgtgtgcctggtgacctacatggtcatggccgccatcctgcacaagctggaccag
ttggatgccagccggggccgcgccatccctttctgtgggcagcggggccgcttcaagtac
gagatcctcgtcaagacaggctggggccggggctcaggtaccacggcccacgtgggcatc
atgctgtatggggtggacagccggagcggccaccggcacctggacggcgacagagccttc
caccgcaacagcctggacatcttccggatcgccaccccgcacagcctgggtagcgtgtgg
aagatccgagtgtggcacgacaacaaagggctcagccctgcctggttcctgcagcacgtc
atcgtcagggacctgcagacggcacgcagcgccttcttcctggtcaatgactggctttcg
gtggagacggaggccaacgggggcctggtggagaaggaggtgctggccgcgagcgacgca
gcccttttgcgcttccggcgcctgctggtggctgagctgcagcgtggcttctttgacaag
cacatctggctctccatatgggaccggccgcctcgtagccgtttcactcgcatccagagg
gccacctgctgcgttctcctcatctgcctcttcctgggcgccaacgccgtgtggtacggg
gctgttggcgactctgcctacagcacggggcatgtgtccaggctgagcccgctgagcgtc
gacacagtcgctgttggcctggtgtccagcgtggttgtctatcccgtctacctggccatc
ctttttctcttccggatgtcccggagcaaggtggctgggagcccgagccccacacctgcc
gggcagcaggtgctggacatcgacagctgcctggactcgtccgtgctggacagctccttc
ctcacgttctcaggcctccacgctgagcaggcctttgttggacagatgaagagtgacttg
tttctggatgattctaagagtctggtgtgctggccctccggcgagggaacgctcagttgg
ccggacctgctcagtgacccgtccattgtgggtagcaatctgcggcagctggcacggggc
caggcgggccatgggctgggcccagaggaggacggcttctccctggccagcccctactcg
cctgccaaatccttctcagcatcagatgaagacctgatccagcaggtccttgccgagggg
gtcagcagcccagcccctacccaagacacccacatggaaacggacctgctcagcagcctg
tccagcactcctggggagaagacagagacgctggcgctgcagaggctgggggagctgggg
ccacccagcccaggcctgaactgggaacagccccaggcagcgaggctgtccaggacagga
ctggtggagggtctgcggaagcgcctgctgccggcctggtgtgcctccctggcccacggg
ctcagcctgctcctggtggctgtggctgtggctgtctcagggtgggtgggtgcgagcttc
cccccgggcgtgagtgttgcgtggctcctgtccagcagcgccagcttcctggcctcattc
ctcggctgggagccactgaaggtcttgctggaagccctgtacttctcactggtggccaag
cggctgcacccggatgaagatgacaccctggtagagagcccggctgtgacgcctgtgagc
gcacgtgtgccccgcgtacggccaccccacggctttgcactcttcctggccaaggaagaa
gcccgcaaggtcaagaggctacatggcatgctgcggagcctcctggtgtacatgcttttt
ctgctggtgaccctgctggccagctatggggatgcctcatgccatgggcacgcctaccgt
ctgcaaagcgccatcaagcaggagctgcacagccgggccttcctggccatcacgcggtct
gaggagctctggccatggatggcccacgtgctgctgccctacgtccacgggaaccagtcc
agcccagagctggggcccccacggctgcggcaggtgcggctgcaggaagcactctaccca
gaccctcccggccccagggtccacacgtgctcggccgcaggaggcttcagcaccagcgat
tacgacgttggctgggagagtcctcacaatggctcggggacgtgggcctattcagcgccg
gatctgctgggggcatggtcctggggctcctgtgccgtgtatgacagcgggggctacgtg
caggagctgggcctgagcctggaggagagccgcgaccggctgcgcttcctgcagctgcac
aactggctggacaacaggagccgcgctgtgttcctggagctcacgcgctacagcccggcc
gtggggctgcacgccgccgtcacgctgcgcctcgagttcccggcggccggccgcgccctg
gccgccctcagcgtccgcccctttgcgctgcgccgcctcagcgcgggcctctcgctgcct
ctgctcacctcggtgtgcctgctgctgttcgccgtgcacttcgccgtggccgaggcccgt
acttggcacagggaagggcgctggcgcgtgctgcggctcggagcctgggcgcggtggctg
ctggtggcgctgacggcggccacggcactggtacgcctcgcccagctgggtgccgctgac
cgccagtggacccgtttcgtgcgcggccgcccgcgccgcttcactagcttcgaccaggtg
gcgcagctgagctccgcagcccgtggcctggcggcctcgctgctcttcctgcttttggtc
aaggctgcccagcagctacgcttcgtgcgccagtggtccgtctttggcaagacattatgc
cgagctctgccagagctcctgggggtcaccttgggcctggtggtgctcggggtagcctac
gcccagctggccatcctgctcgtgtcttcctgtgtggactccctctggagcgtggcccag
gccctgttggtgctgtgccctgggactgggctctctaccctgtgtcctgccgagtcctgg
cacctgtcacccctgctgtgtgtggggctctgggcactgcggctgtggggcgccctacgg
ctgggggctgttattctccgctggcgctaccacgccttgcgtggagagctgtaccggccg
gcctgggagccccaggactacgagatggtggagttgttcctgcgcaggctgcgcctctgg
atgggcctcagcaaggtcaaggagttccgccacaaagtccgctttgaagggatggagccg
ctgccctctcgctcctccaggggctccaaggtatccccggatgtgcccccacccagcgct
ggctccgatgcctcgcacccctccacctcctccagccagctggatgggctgagcgtgagc
ctgggccggctggggacaaggtgtgagcctgagccctcccgcctccaagccgtgttcgag
gccctgctcacccagtttgaccgactcaaccaggccacagaggacgtctaccagctggag
cagcagctgcacagcctgcaaggccgcaggagcagccgggcgcccgccggatcttcccgt
ggcccatccccgggcctgcggccagcactgcccagccgccttgcccgggccagtcggggt
gtggacctggccactggccccagcaggacaccccttcgggccaagaacaaggtccacccc
agcagcacttag
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