Homo sapiens (human): 5333 Help Entry 5333              CDS       T01001                                  Symbol PLCD1, NDNC3, PLC-III Name (RefSeq) phospholipase C delta 1   KO K05857   phosphatidylinositol phospholipase C, delta [EC:3.1.4.11] Organism hsa  Homo sapiens (human) Pathway hsa00562   Inositol phosphate metabolism hsa01100   Metabolic pathways hsa04020   Calcium signaling pathway hsa04070   Phosphatidylinositol signaling system hsa04919   Thyroid hormone signaling pathway hsa04933   AGE-RAGE signaling pathway in diabetic complications hsa05131   Shigellosis Module hsa_M00130   Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Network nt06528  Calcium signaling   Element N01655   Ca2+-PLCD-ITPR signaling pathway Disease H01307   Nonsyndromic congenital nail disorder Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09101 Carbohydrate metabolism    00562 Inositol phosphate metabolism     5333 (PLCD1)  09130 Environmental Information Processing   09132 Signal transduction    04020 Calcium signaling pathway     5333 (PLCD1)    04070 Phosphatidylinositol signaling system     5333 (PLCD1)  09150 Organismal Systems   09152 Endocrine system    04919 Thyroid hormone signaling pathway     5333 (PLCD1)  09160 Human Diseases   09171 Infectious disease: bacterial    05131 Shigellosis     5333 (PLCD1)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     5333 (PLCD1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hsa04131]     5333 (PLCD1) Enzymes [BR:hsa01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.4  Phosphoric-diester hydrolases     3.1.4.11  phosphoinositide phospholipase C      5333 (PLCD1) Membrane trafficking [BR:hsa04131]  Exocytosis   Calcium ion-dependent exocytosis    Phospholipases     5333 (PLCD1)  Endocytosis   Macropinocytosis    Phospholipase C     5333 (PLCD1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PI-PLC-X PI-PLC-Y EF-hand_like EF-hand_10 C2 PH_12 EF-hand_7 PH EF-hand_6 EF-hand_15 EF-hand_1 WHD_MCM8 EF-hand_5 TEP1_N Motif Other DBs NCBI-GeneID:  5333 NCBI-ProteinID:  NP_006216 OMIM:  602142 HGNC:  9060 Ensembl:  ENSG00000187091 UniProt:  P51178 A8K8F9 A0A384MR47 LinkDB All DBs Position 3:complement(38007496..38029642) Genome browser AA seq 756 aa AA seqDB search MDSGRDFLTLHGLQDDEDLQALLKGSQLLKVKSSSWRRERFYKLQEDCKTIWQESRKVMR TPESQLFSIEDIQEVRMGHRTEGLEKFARDVPEDRCFSIVFKDQRNTLDLIAPSPADAQH WVLGLHKIIHHSGSMDQRQKLQHWIHSCLRKADKNKDNKMSFKELQNFLKELNIQVDDSY ARKIFRECDHSQTDSLEDEEIEAFYKMLTQRVEIDRTFAEAAGSGETLSVDQLVTFLQHQ QREEAAGPALALSLIERYEPSETAKAQRQMTKDGFLMYLLSADGSAFSLAHRRVYQDMGQ PLSHYLVSSSHNTYLLEDQLAGPSSTEAYIRALCKGCRCLELDCWDGPNQEPIIYHGYTF TSKILFCDVLRAIRDYAFKASPYPVILSLENHCTLEQQRVMARHLHAILGPMLLNRPLDG VTNSLPSPEQLKGKILLKGKKLGGLLPPGGEGGPEATVVSDEDEAAEMEDEAVRSRVQHK PKEDKLRLAQELSDMVIYCKSVHFGGFSSPGTPGQAFYEMASFSENRALRLLQESGNGFV RHNVGHLSRIYPAGWRTDSSNYSPVEMWNGGCQIVALNFQTPGPEMDVYQGRFQDNGACG YVLKPAFLRDPNGTFNPRALAQGPWWARKRLNIRVISGQQLPKVNKNKNSIVDPKVTVEI HGVSRDVASRQTAVITNNGFNPWWDTEFAFEVVVPDLALIRFLVEDYDASSKNDFIGQST IPLNSLKQGYRHVHLMSKNGDQHPSATLFVKISLQD NT seq 2271 nt NT seq  +upstreamnt  +downstreamnt atggactcgggccgggacttcctgaccctgcacggcctacaggatgatgaggatctacag gcgctgctgaagggcagccagctcctgaaggtgaagtccagctcatggaggagagagcgc ttctacaagttgcaggaggactgcaagaccatctggcaggagtcccgcaaggtcatgcgg accccggagtcccagctgttctccatcgaggacattcaggaggtgcgaatggggcaccgc acggagggtctggagaagttcgcccgtgatgtgcccgaggaccgctgcttctccattgtc ttcaaggaccagcgcaatacactagacctcatcgccccatcgccagctgatgcccagcac tgggtgctggggctgcacaagatcatccaccactcaggctccatggaccagcgtcagaag ctacagcactggattcactcctgcttgcgaaaagctgacaaaaacaaggacaacaagatg agcttcaaggagctgcagaacttcctgaaggagctcaacatccaggtggacgacagctat gcccggaagatcttcagggagtgtgaccactcccagacagactccctggaggacgaggag attgaggccttctacaagatgctgacccagcgggtggagatcgaccgcaccttcgccgag gccgcgggctcaggggagactctgtcggtggatcagttagtgacgttcctgcagcaccag cagcgggaggaggcggcagggcctgcgctggccctctccctcattgagcgctacgagccc agcgagactgccaaggcgcagcggcagatgaccaaggacggcttcctcatgtacttactg tcggctgacggcagcgccttcagcctggcacaccgccgtgtctaccaggacatgggccag ccacttagccactacctggtgtcctcttcacacaacacctacctgctggaggaccagcta gccgggcccagcagcactgaagcctacatccgggcactgtgcaaaggctgccgatgcctg gagcttgactgctgggacgggcccaaccaggaaccaatcatctaccacggctatactttc acttccaagatcctcttctgcgatgtgctcagggccatccgggactatgccttcaaggcg tccccctaccctgtcatcctatccctggagaaccactgcacactggagcagcagcgcgtg atggcgcggcacctgcatgccatcctgggccccatgctgttgaaccgaccactggatggg gtcaccaacagcctgccctcccctgagcaactgaaggggaagatcctgctgaaggggaag aagctcggggggctcctgccccctggaggggagggtggccctgaggccactgtggtgtca gacgaagacgaggctgctgagatggaggatgaggcagtgaggagccgtgtgcagcacaag cccaaggaggacaagctcaggctagcacaggagctctctgacatggtcatttactgcaag agtgtccactttgggggcttctccagtcctggcacccctggacaggccttctacgagatg gcgtccttctctgagaaccgtgcccttcgactgctccaagaatcaggaaacggctttgtc cgccacaacgtggggcacctgagcagaatctacccggctggatggagaacagactcctcc aactacagccccgtggagatgtggaatgggggctgccagatcgtggccctgaatttccag acacctgggccagagatggacgtgtaccagggccgcttccaggacaacggggcctgtggg tacgtgctgaagcccgccttcctgcgagaccccaacggcacctttaacccccgcgccctg gctcaggggccctggtgggcacggaagcggctcaacatcagggtcatttcggggcagcag ctgccaaaagtcaacaagaataagaattcaattgtggaccccaaagtgacagtggagatc catggcgtgagccgggacgtggccagccgccagactgctgtcatcaccaacaatggtttc aacccatggtgggacacggagtttgcgtttgaggtagttgtgcctgaccttgccctcatc cgcttcttggtggaagattatgatgcctcctccaagaatgacttcattggccagagtacc atccccttgaacagcctcaagcaaggataccgccatgtccacctcatgtctaagaacggg gaccagcatccatcagccaccctctttgtgaagatctccctccaggactag

Homo sapiens (human): 113026 Help Entry 113026            CDS       T01001                                  Symbol PLCD3, PLC-delta-3 Name (RefSeq) phospholipase C delta 3   KO K05857   phosphatidylinositol phospholipase C, delta [EC:3.1.4.11] Organism hsa  Homo sapiens (human) Pathway hsa00562   Inositol phosphate metabolism hsa01100   Metabolic pathways hsa04020   Calcium signaling pathway hsa04070   Phosphatidylinositol signaling system hsa04919   Thyroid hormone signaling pathway hsa04933   AGE-RAGE signaling pathway in diabetic complications hsa05131   Shigellosis Module hsa_M00130   Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Network nt06528  Calcium signaling   Element N01655   Ca2+-PLCD-ITPR signaling pathway Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09101 Carbohydrate metabolism    00562 Inositol phosphate metabolism     113026 (PLCD3)  09130 Environmental Information Processing   09132 Signal transduction    04020 Calcium signaling pathway     113026 (PLCD3)    04070 Phosphatidylinositol signaling system     113026 (PLCD3)  09150 Organismal Systems   09152 Endocrine system    04919 Thyroid hormone signaling pathway     113026 (PLCD3)  09160 Human Diseases   09171 Infectious disease: bacterial    05131 Shigellosis     113026 (PLCD3)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     113026 (PLCD3)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hsa04131]     113026 (PLCD3) Enzymes [BR:hsa01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.4  Phosphoric-diester hydrolases     3.1.4.11  phosphoinositide phospholipase C      113026 (PLCD3) Membrane trafficking [BR:hsa04131]  Exocytosis   Calcium ion-dependent exocytosis    Phospholipases     113026 (PLCD3)  Endocytosis   Macropinocytosis    Phospholipase C     113026 (PLCD3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PI-PLC-X PI-PLC-Y EF-hand_10 EF-hand_like C2 EF-hand_7 EF-hand_15 PH S_100 WHD_MCM8 IgD_del_linker TEP1_N SPARC_Ca_bdg CTD1 Motif Other DBs NCBI-GeneID:  113026 NCBI-ProteinID:  NP_588614 OMIM:  608795 HGNC:  9061 Ensembl:  ENSG00000161714 UniProt:  Q8N3E9 LinkDB All DBs Position 17:complement(45108959..45132515) Genome browser AA seq 789 aa AA seqDB search MLCGRWRRCRRPPEEPPVAAQVAAQVAAPVALPSPPTPSDGGTKRPGLRALKKMGLTEDE DVRAMLRGSRLRKIRSRTWHKERLYRLQEDGLSVWFQRRIPRAPSQHIFFVQHIEAVREG HQSEGLRRFGGAFAPARCLTIAFKGRRKNLDLAAPTAEEAQRWVRGLTKLRARLDAMSQR ERLDHWIHSYLHRADSNQDSKMSFKEIKSLLRMVNVDMNDMYAYLLFKECDHSNNDRLEG AEIEEFLRRLLKRPELEEIFHQYSGEDRVLSAPELLEFLEDQGEEGATLARAQQLIQTYE LNETAKQHELMTLDGFMMYLLSPEGAALDNTHTCVFQDMNQPLAHYFISSSHNTYLTDSQ IGGPSSTEAYVRAFAQGCRCVELDCWEGPGGEPVIYHGHTLTSKILFRDVVQAVRDHAFT LSPYPVILSLENHCGLEQQAAMARHLCTILGDMLVTQALDSPNPEELPSPEQLKGRVLVK GKKLPAARSEDGRALSDREEEEEDDEEEEEEVEAAAQRRLAKQISPELSALAVYCHATRL RTLHPAPNAPQPCQVSSLSERKAKKLIREAGNSFVRHNARQLTRVYPLGLRMNSANYSPQ EMWNSGCQLVALNFQTPGYEMDLNAGRFLVNGQCGYVLKPACLRQPDSTFDPEYPGPPRT TLSIQVLTAQQLPKLNAEKPHSIVDPLVRIEIHGVPADCARQETDYVLNNGFNPRWGQTL QFQLRAPELALVRFVVEDYDATSPNDFVGQFTLPLSSLKQGYRHIHLLSKDGASLSPATL FIQIRIQRS NT seq 2370 nt NT seq  +upstreamnt  +downstreamnt atgctgtgcggccgctggaggcgttgccgccgcccgcccgaggagcccccggtggccgcc caggtcgcagcccaagtcgcggcgccggtcgctctcccgtccccgccgactccctccgat ggcggcaccaagaggcccgggctgcgggcgctgaagaagatgggcctgacggaggacgag gacgtgcgcgccatgctgcggggctcccggctccgcaagatccgctcgcgcacgtggcac aaggagcggctgtaccggctgcaggaggacggcctgagcgtgtggttccagcggcgcatc ccgcgtgcgccatcgcagcacatcttcttcgtgcagcacatcgaggcggtccgcgagggc caccagtccgagggcctgcggcgcttcgggggtgccttcgcgccagcgcgctgcctcacc atcgccttcaagggccgccgcaagaacctggacctggcggcgcccacggctgaggaagcg cagcgctgggtgcgcggtctgaccaagctccgcgcgcgcctggacgccatgagccagcgc gagcggctagaccactggatccactcctatctgcaccgggctgactccaaccaggacagc aagatgagcttcaaggagatcaagagcctgctgagaatggtcaacgtggacatgaacgac atgtacgcctacctcctcttcaaggagtgtgaccactccaacaacgaccgtctagagggg gctgagatcgaggagttcctgcggcggctgctgaagcggccggagctggaggagatcttc catcagtactcgggcgaggaccgcgtgctgagtgcccctgagctgctggagttcctggag gaccagggcgaggagggcgccacactggcccgcgcccagcagctcattcagacctatgag ctcaacgagacagccaagcagcatgagctgatgacactggatggcttcatgatgtacctg ttgtcgccggagggggctgccttggacaacacccacacgtgtgtgttccaggacatgaac cagccccttgcccactacttcatctcttcctcccacaacacctatctgactgactcccag atcggggggcccagcagcaccgaggcctatgttagggcctttgcccagggatgccgctgc gtggagctggactgctgggaggggccaggaggggagcccgtcatctatcatggccatacc ctcacctccaagattctcttccgggacgtggtccaagccgtgcgcgaccatgccttcacg ctgtccccttaccctgtcatcctatccctggagaaccactgcgggctggagcagcaggct gccatggcccgccacctctgcaccatcctgggggacatgctggtgacacaggcgctggac tccccaaatcccgaggagctgccatccccagagcagctgaagggccgggtcctggtgaag ggaaagaagttgcccgctgctcggagcgaggatggccgggctctgtcggatcgggaggag gaggaggaggatgacgaggaggaagaagaggaggtggaggctgcagcgcagaggcggctg gccaagcagatctccccggagctgtcggccctggctgtgtactgccacgccacccgcctg cggaccctgcaccctgcccccaacgccccacaaccctgccaggtcagctccctcagcgag cgcaaagccaagaaactcattcgggaggcagggaacagctttgtcaggcacaatgcccgc cagctgacccgcgtgtacccgctggggctgcggatgaactcagccaactacagtccccag gagatgtggaactcgggctgtcagctggtggccttgaacttccagacgccaggctacgag atggacctcaatgccgggcgcttcctagtcaatgggcagtgtggctacgtcctaaaacct gcctgcctgcggcaacctgactcgacctttgaccccgagtacccaggacctcccagaacc actctcagcatccaggtgctgactgcacagcagctgcccaagctgaatgccgagaagcca cactccattgtggaccccctggtgcgcattgagatccatggggtgcccgcagactgtgcc cggcaggagactgactacgtgctcaacaatggcttcaacccccgctgggggcagaccctg cagttccagctgcgggctccggagctggcactggtccggtttgtggtggaagattatgac gccacctcccccaatgactttgtgggccagtttacactgcctcttagcagcctaaagcaa gggtaccgccacatacacctgctttccaaggacggggcctcactgtcaccagccacgctc ttcatccaaatccgcatccagcgctcctga

Homo sapiens (human): 84812 Help Entry 84812             CDS       T01001                                  Symbol PLCD4 Name (RefSeq) phospholipase C delta 4   KO K05857   phosphatidylinositol phospholipase C, delta [EC:3.1.4.11] Organism hsa  Homo sapiens (human) Pathway hsa00562   Inositol phosphate metabolism hsa01100   Metabolic pathways hsa04020   Calcium signaling pathway hsa04070   Phosphatidylinositol signaling system hsa04919   Thyroid hormone signaling pathway hsa04933   AGE-RAGE signaling pathway in diabetic complications hsa05131   Shigellosis Module hsa_M00130   Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Network nt06528  Calcium signaling   Element N01655   Ca2+-PLCD-ITPR signaling pathway Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09101 Carbohydrate metabolism    00562 Inositol phosphate metabolism     84812 (PLCD4)  09130 Environmental Information Processing   09132 Signal transduction    04020 Calcium signaling pathway     84812 (PLCD4)    04070 Phosphatidylinositol signaling system     84812 (PLCD4)  09150 Organismal Systems   09152 Endocrine system    04919 Thyroid hormone signaling pathway     84812 (PLCD4)  09160 Human Diseases   09171 Infectious disease: bacterial    05131 Shigellosis     84812 (PLCD4)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     84812 (PLCD4)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hsa04131]     84812 (PLCD4) Enzymes [BR:hsa01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.4  Phosphoric-diester hydrolases     3.1.4.11  phosphoinositide phospholipase C      84812 (PLCD4) Membrane trafficking [BR:hsa04131]  Exocytosis   Calcium ion-dependent exocytosis    Phospholipases     84812 (PLCD4)  Endocytosis   Macropinocytosis    Phospholipase C     84812 (PLCD4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PI-PLC-X PI-PLC-Y EF-hand_like EF-hand_10 C2 EF-hand_7 PH EF-hand_1 EF-hand_6 EF-hand_5 PH_12 EF-hand_PLCG2 GDPD EF-hand_15 Wap1 EF-hand_8 Motif Other DBs NCBI-GeneID:  84812 NCBI-ProteinID:  NP_116115 OMIM:  605939 HGNC:  9062 Ensembl:  ENSG00000115556 UniProt:  Q9BRC7 LinkDB All DBs Position 2:218607899..218637175 Genome browser AA seq 762 aa AA seqDB search MASLLQDQLTTDQDLLLMQEGMPMRKVRSKSWKKLRYFRLQNDGMTVWHARQARGSAKPS FSISDVETIRNGHDSELLRSLAEELPLEQGFTIVFHGRRSNLDLMANSVEEAQIWMRGLQ LLVDLVTSMDHQERLDQWLSDWFQRGDKNQDGKMSFQEVQRLLHLMNVEMDQEYAFSLFQ AADTSQSGTLEGEEFVQFYKALTKRAEVQELFESFSADGQKLTLLEFLDFLQEEQKERDC TSELALELIDRYEPSDSGKLRHVLSMDGFLSYLCSKDGDIFNPACLPIYQDMTQPLNHYF ICSSHNTYLVGDQLCGQSSVEGYIRALKRGCRCVEVDVWDGPSGEPVVYHGHTLTSRILF KDVVATVAQYAFQTSDYPVILSLETHCSWEQQQTMARHLTEILGEQLLSTTLDGVLPTQL PSPEELRRKILVKGKKLTLEEDLEYEEEEAEPELEESELALESQFETEPEPQEQNLQNKD KKKKSKPILCPALSSLVIYLKSVSFRSFTHSKEHYHFYEISSFSETKAKRLIKEAGNEFV QHNTWQLSRVYPSGLRTDSSNYNPQELWNAGCQMVAMNMQTAGLEMDICDGHFRQNGGCG YVLKPDFLRDIQSSFHPEKPISPFKAQTLLIQVISGQQLPKVDKTKEGSIVDPLVKVQIF GVRLDTARQETNYVENNGFNPYWGQTLCFRVLVPELAMLRFVVMDYDWKSRNDFIGQYTL PWTCMQQGYRHIHLLSKDGISLRPASIFVYICIQEGLEGDES NT seq 2289 nt NT seq  +upstreamnt  +downstreamnt atggcgtccctgctgcaagaccagctgaccactgatcaggacttgctgctgatgcaggaa ggcatgccgatgcgcaaggtgaggtccaaaagctggaagaagctaagatacttcagactt cagaatgacggcatgacagtctggcatgcacggcaggccaggggcagtgccaagcccagc ttctcaatctctgatgtggagacaatacgtaatggccatgattccgagttgctgcgtagc ctggcagaggagctccccctggagcagggcttcaccattgtcttccatggccgccgctcc aacctggacctgatggccaacagtgttgaggaggcccagatatggatgcgagggctccag ctgttggtggatcttgtcaccagcatggaccatcaggagcgcctggaccaatggctgagc gattggtttcaacgtggagacaaaaatcaggatggtaagatgagtttccaagaagttcag cggttattgcacctaatgaatgtggaaatggaccaagaatatgccttcagtctttttcag gcagcagacacgtcccagtctggaaccctggaaggagaagaattcgtacagttctataag gcattgactaaacgtgctgaggtgcaggaactgtttgaaagtttttcagctgatgggcag aagctgactctgctggaatttttggatttcctccaagaggagcagaaggagagagactgc acctctgagcttgctctggaactcattgaccgctatgaaccttcagacagtggcaaactg cggcatgtgctgagtatggatggcttcctcagctacctctgctctaaggatggagacatc ttcaacccagcctgcctccccatctatcaggatatgactcaacccctgaaccactacttc atctgctcttctcataacacctacctagtgggggaccagctttgtggccagagcagcgtc gagggatatatacgggccctgaagcgggggtgccgctgcgtggaggtggatgtatgggat ggacctagcggggaacctgtcgtttaccacggacacaccctgacctcccgcatcctgttc aaagatgtcgtggccacagtagcacagtatgccttccagacatcagactacccagtcatc ttgtccctggagacccactgcagctgggagcagcagcagaccatggcccgtcatctgact gagatcctgggggagcagctgctgagcaccaccttggatggggtgctgcccactcagctg ccctcgcctgaggagcttcggaggaagatcctggtgaaggggaagaagttaacacttgag gaagacctggaatatgaggaagaggaagcagaacctgagttggaagagtcagaattggcg ctggagtcccagtttgagactgagcctgagccccaggagcagaaccttcagaataaggac aaaaagaagaaatccaagcccatcttgtgtccagccctctcttccctggttatctacttg aagtctgtctcattccgcagcttcacacattcaaaggagcactaccacttctacgagata tcatctttctctgaaaccaaggccaagcgcctcatcaaggaggctggcaatgagtttgtg cagcacaatacttggcagttaagccgtgtgtatcccagcggcctgaggacagactcttcc aactacaacccccaggaactctggaatgcaggctgccagatggtggccatgaatatgcag actgcagggcttgaaatggacatctgtgatgggcatttccgccagaatggcggctgtggc tatgtgctgaagccagacttcctgcgtgatatccagagttctttccaccctgagaagccc atcagccctttcaaagcccagactctcttaatccaggtgatcagcggtcagcaactcccc aaagtggacaagaccaaagaggggtccattgtggatccactggtgaaagtgcagatcttt ggcgttcgtctagacacagcacggcaggagaccaactatgtggagaacaatggttttaat ccatactgggggcagacactatgtttccgggtgctggtgcctgaacttgccatgctgcgt tttgtggtaatggattatgactggaaatcccgaaatgactttattggtcagtacaccctg ccttggacctgcatgcaacaaggttaccgccacattcacctgctgtccaaagatggcatc agcctccgcccagcttccatctttgtgtatatctgcatccaggaaggcctggagggggat gagtcctga

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