Homo sapiens (human): 53353 Help Entry 53353             CDS       T01001                                  Symbol LRP1B, LRP-1B, LRP-DIT, LRPDIT Name (RefSeq) LDL receptor related protein 1B   KO K20049   low-density lipoprotein receptor-related protein 1B Organism hsa  Homo sapiens (human) Brite KEGG Orthology (KO) [BR:hsa00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hsa04131]     53353 (LRP1B) Membrane trafficking [BR:hsa04131]  Endocytosis   Clathrin-mediated endocytosis    Low-density lipoprotein receptor (LDLR) family proteins     53353 (LRP1B) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Ldl_recept_a Ldl_recept_b FXa_inhibition DUF5050 cEGF SGL EGF_CA EGF EGF_3 Motif Other DBs NCBI-GeneID:  53353 NCBI-ProteinID:  NP_061027 OMIM:  608766 HGNC:  6693 Ensembl:  ENSG00000168702 UniProt:  Q9NZR2 LinkDB All DBs Position 2:complement(140231423..142131016) Genome browser AA seq 4599 aa AA seqDB search MSEFLLALLTLSGLLPIARVLTVGADRDQQLCDPGEFLCHDHVTCVSQSWLCDGDPDCPD DSDESLDTCPEEVEIKCPLNHIACLGTNKCVHLSQLCNGVLDCPDGYDEGVHCQELLSNC QQLNCQYKCTMVRNSTRCYCEDGFEITEDGRSCKDQDECAVYGTCSQTCRNTHGSYTCSC VEGYLMQPDNRSCKAKIEPTDRPPILLIANFETIEVFYLNGSKMATLSSVNGNEIHTLDF IYNEDMICWIESRESSNQLKCIQITKAGGLTDEWTINILQSFHNVQQMAIDWLTRNLYFV DHVGDRIFVCNSNGSVCVTLIDLELHNPKAIAVDPIAGKLFFTDYGNVAKVERCDMDGMN RTRIIDSKTEQPAALALDLVNKLVYWVDLYLDYVGVVDYQGKNRHTVIQGRQVRHLYGIT VFEDYLYATNSDNYNIVRINRFNGTDIHSLIKIENAWGIRIYQKRTQPTVRSHACEVDPY GMPGGCSHICLLSSSYKTRTCRCRTGFNLGSDGRSCKRPKNELFLFYGKGRPGIVRGMDL NTKIADEYMIPIENLVNPRALDFHAETNYIYFADTTSFLIGRQKIDGTERETILKDDLDN VEGIAVDWIGNNLYWTNDGHRKTINVARLEKASQSRKTLLEGEMSHPRGIVVDPVNGWMY WTDWEEDEIDDSVGRIEKAWMDGFNRQIFVTSKMLWPNGLTLDFHTNTLYWCDAYYDHIE KVFLNGTHRKIVYSGRELNHPFGLSHHGNYVFWTDYMNGSIFQLDLITSEVTLLRHERPP LFGLQIYDPRKQQGDNMCRVNNGGCSTLCLAIPGGRVCACADNQLLDENGTTCTFNPGEA LPHICKAGEFRCKNRHCIQARWKCDGDDDCLDGSDEDSVNCFNHSCPDDQFKCQNNRCIP KRWLCDGANDCGSNEDESNQTCTARTCQVDQFSCGNGRCIPRAWLCDREDDCGDQTDEMA SCEFPTCEPLTQFVCKSGRCISSKWHCDSDDDCGDGSDEVGCVHSCFDNQFRCSSGRCIP GHWACDGDNDCGDFSDEAQINCTKEEIHSPAGCNGNEFQCHPDGNCVPDLWRCDGEKDCE DGSDEKGCNGTIRLCDHKTKFSCWSTGRCINKAWVCDGDIDCEDQSDEDDCDSFLCGPPK HPCANDTSVCLQPEKLCNGKKDCPDGSDEGYLCDECSLNNGGCSNHCSVVPGRGIVCSCP EGLQLNKDNKTCEIVDYCSNHLKCSQVCEQHKHTVKCSCYEGWKLDVDGESCTSVDPFEA FIIFSIRHEIRRIDLHKRDYSLLVPGLRNTIALDFHFNQSLLYWTDVVEDRIYRGKLSES GGVSAIEVVVEHGLATPEGLTVDWIAGNIYWIDSNLDQIEVAKLDGSLRTTLIAGAMEHP RAIALDPRYGILFWTDWDANFPRIESASMSGAGRKTIYKDMKTGAWPNGLTVDHFEKRIV WTDARSDAIYSALYDGTNMIEIIRGHEYLSHPFAVSLYGSEVYWTDWRTNTLSKANKWTG QNVSVIQKTSAQPFDLQIYHPSRQPQAPNPCAANDGKGPCSHMCLINHNRSAACACPHLM KLSSDKKTCYEMKKFLLYARRSEIRGVDIDNPYFNFITAFTVPDIDDVTVIDFDASEERL YWTDIKTQTIKRAFINGTGLETVISRDIQSIRGLAVDWVSRNLYWISSEFDETQINVARL DGSLKTSIIHGIDKPQCLAAHPVRGKLYWTDGNTINMANMDGSNSKILFQNQKEPVGLSI DYVENKLYWISSGNGTINRCNLDGGNLEVIESMKEELTKATALTIMDKKLWWADQNLAQL GTCSKRDGRNPTILRNKTSGVVHMKVYDKEAQQGSNSCQLNNGGCSQLCLPTSETTRTCM CTVGYYLQKNRMSCQGIESFLMYSVHEGIRGIPLEPSDKMDALMPISGTSFAVGIDFHAE NDTIYWTDMGFNKISRAKRDQTWKEDIITNGLGRVEGIAVDWIAGNIYWTDHGFNLIEVA RLNGSFRYVIISQGLDQPRSIAVHPEKGLLFWTEWGQMPCIGKARLDGSEKVVLVSMGIA WPNGISIDYEENKLYWCDARTDKIERIDLETGGNREMVLSGSNVDMFSVAVFGAYIYWSD RAHANGSVRRGHKNDATETITMRTGLGVNLKEVKIFNRVREKGTNVCARDNGGCKQLCLY RGNSRRTCACAHGYLAEDGVTCLRHEGYLLYSGRTILKSIHLSDETNLNSPIRPYENPRY FKNVIALAFDYNQRRKGTNRIFYSDAHFGNIQLIKDNWEDRQVIVENVGSVEGLAYHRAW DTLYWTSSTTSSITRHTVDQTRPGAFDREAVITMSEDDHPHVLALDECQNLMFWTNWNEQ HPSIMRSTLTGKNAQVVVSTDILTPNGLTIDYRAEKLYFSDGSLGKIERCEYDGSQRHVI VKSGPGTFLSLAVYDNYIFWSDWGRRAILRSNKYTGGDTKILRSDIPHQPMGIIAVANDT NSCELSPCALLNGGCHDLCLLTPNGRVNCSCRGDRILLEDNRCVTKNSSCNAYSEFECGN GECIDYQLTCDGIPHCKDKSDEKLLYCENRSCRRGFKPCYNRRCIPHGKLCDGENDCGDN SDELDCKVSTCATVEFRCADGTCIPRSARCNQNIDCADASDEKNCNNTDCTHFYKLGVKT TGFIRCNSTSLCVLPTWICDGSNDCGDYSDELKCPVQNKHKCEENYFSCPSGRCILNTWI CDGQKDCEDGRDEFHCDSSCSWNQFACSAQKCISKHWICDGEDDCGDGLDESDSICGAIT CAADMFSCQGSRACVPRHWLCDGERDCPDGSDELSTAGCAPNNTCDENAFMCHNKVCIPK QFVCDHDDDCGDGSDESPQCGYRQCGTEEFSCADGRCLLNTQWQCDGDFDCPDHSDEAPL NPKCKSAEQSCNSSFFMCKNGRCIPSGGLCDNKDDCGDGSDERNCHINECLSKKVSGCSQ DCQDLPVSYKCKCWPGFQLKDDGKTCVDIDECSSGFPCSQQCINTYGTYKCLCTDGYEIQ PDNPNGCKSLSDEEPFLILADHHEIRKISTDGSNYTLLKQGLNNVIAIDFDYREEFIYWI DSSRPNGSRINRMCLNGSDIKVVHNTAVPNALAVDWIGKNLYWSDTEKRIIEVSKLNGLY PTILVSKRLKFPRDLSLDPQAGYLYWIDCCEYPHIGRVGMDGTNQSVVIETKISRPMALT IDYVNRRLYWADENHIEFSNMDGSHRHKVPNQDIPGVIALTLFEDYIYWTDGKTKSLSRA HKTSGADRLSLIYSWHAITDIQVYHSYRQPDVSKHLCMINNGGCSHLCLLAPGKTHTCAC PTNFYLAADNRTCLSNCTASQFRCKTDKCIPFWWKCDTVDDCGDGSDEPDDCPEFRCQPG RFQCGTGLCALPAFICDGENDCGDNSDELNCDTHVCLSGQFKCTKNQKCIPVNLRCNGQD DCGDEEDERDCPENSCSPDYFQCKTTKHCISKLWVCDEDPDCADASDEANCDKKTCGPHE FQCKNNNCIPDHWRCDSQNDCSDNSDEENCKPQTCTLKDFLCANGDCVSSRFWCDGDFDC ADGSDERNCETSCSKDQFRCSNGQCIPAKWKCDGHEDCKYGEDEKSCEPASPTCSSREYI CASDGCISASLKCNGEYDCADGSDEMDCVTECKEDQFRCKNKAHCIPIRWLCDGIHDCVD GSDEENCERGGNICRADEFLCNNSLCKLHFWVCDGEDDCGDNSDEAPDMCVKFLCPSTRP HRCRNNRICLQSEQMCNGIDECGDNSDEDHCGGKLTYKARPCKKDEFACSNKKCIPMDLQ CDRLDDCGDGSDEQGCRIAPTEYTCEDNVNPCGDDAYCNQIKTSVFCRCKPGFQRNMKNR QCEDLNECLVFGTCSHQCINVEGSYKCVCDQNFQERNNTCIAEGSEDQVLYIANDTDILG FIYPFNYSGDHQQISHIEHNSRITGMDVYYQRDMIIWSTQFNPGGIFYKRIHGREKRQAN SGLICPEFKRPRDIAVDWVAGNIYWTDHSRMHWFSYYTTHWTSLRYSINVGQLNGPNCTR LLTNMAGEPYAIAVNPKRGMMYWTVVGDHSHIEEAAMDGTLRRILVQKNLQRPTGLAVDY FSERIYWADFELSIIGSVLYDGSNSVVSVSSKQGLLHPHRIDIFEDYIYGAGPKNGVFRV QKFGHGSVEYLALNIDKTKGVLISHRYKQLDLPNPCLDLACEFLCLLNPSGATCVCPEGK YLINGTCNDDSLLDDSCKLTCENGGRCILNEKGDLRCHCWPSYSGERCEVNHCSNYCQNG GTCVPSVLGRPTCSCALGFTGPNCGKTVCEDFCQNGGTCIVTAGNQPYCHCQPEYTGDRC QYYVCHHYCVNSESCTIGDDGSVECVCPTRYEGPKCEVDKCVRCHGGHCIINKDSEDIFC NCTNGKIASSCQLCDGYCYNGGTCQLDPETNVPVCLCSTNWSGTQCERPAPKSSKSDHIS TRSIAIIVPLVLLVTLITTLVIGLVLCKRKRRTKTIRRQPIINGGINVEIGNPSYNMYEV DHDHNDGGLLDPGFMIDPTKARYIGGGPSAFKLPHTAPPIYLNSDLKGPLTAGPTNYSNP VYAKLYMDGQNCRNSLGSVDERKELLPKKIEIGIRETVA NT seq 13800 nt NT seq  +upstreamnt  +downstreamnt atgtccgagtttctcctcgccttactcactctctcgggattattgccgattgccagggtg ctgaccgtgggagccgaccgagatcagcagttgtgtgatcctggtgaatttctttgccac gatcacgtgacttgtgtctcccagagctggctgtgtgatggggaccctgactgccctgat gattcagacgagtctttagatacctgtcccgaggaggtagaaatcaagtgccccttgaat cacattgcttgccttggtaccaacaaatgtgttcatttatcccagctgtgcaatggtgtc ttggactgcccagatgggtatgacgaaggagtacattgtcaggaactgttatccaattgc caacagctgaattgtcagtataaatgtacaatggtcagaaatagtacaagatgttactgt gaggatggattcgaaataacagaagatgggagaagctgtaaagatcaagatgaatgtgct gtttatggtacatgcagccagacctgcagaaacacacatggatcctacacttgcagttgt gtggaaggctacctaatgcagccagacaacagatcttgcaaggctaaaattgaacctaca gatagaccacctatactattaattgcaaattttgaaacaattgaggttttctatcttaat ggaagtaaaatggcaactctaagctcagtcaatggaaatgaaattcatactctggatttt atttataatgaagatatgatttgttggattgaatcaagagaatcttcaaatcaactcaaa tgtatccagataacaaaagcaggaggattaacagatgaatggacaatcaatattcttcaa tccttccacaatgtgcaacaaatggcgattgactggctcactcgaaatctctattttgtg gaccatgtcggtgaccggatctttgtttgtaattccaacggttctgtatgtgtcaccctg attgatctggagcttcacaatcctaaagcaatagcagtagatccaatagcaggaaaactt ttctttactgactacgggaatgtcgccaaagtggagagatgtgacatggatgggatgaac cgaacaaggataattgattcaaagacagagcagccagctgcactggcactagacctagtc aacaaattggtttactgggtagatctttacttggactatgtgggagtagtggactatcaa ggaaaaaatagacacactgtcattcaaggcagacaagttagacatctttatggtataact gtgtttgaagattatttgtatgcaaccaattctgataactacaatatcgtaaggataaac cgatttaatgggactgatattcactcattaattaaaattgagaatgcttggggaatccga atttatcaaaaaagaactcaaccaacagtcagaagccatgcatgtgaagtcgatccatat ggaatgccagggggctgttcacacatctgtctactcagcagcagttacaaaactcggact tgtcgctgcaggactggcttcaacttgggaagtgatggcaggtcatgcaaaagaccaaag aatgagttgttcctcttttatgggaaaggacgcccaggaattgttagaggaatggacttg aataccaagatagctgatgaatacatgatccccatagaaaatctggtaaaccctcgtgct ttagactttcacgcagaaaccaattacatctactttgctgacaccaccagtttcctaatt ggccggcagaagatagatggcacagagagagaaaccatcctgaaagatgatctggataat gtagagggcattgctgtggactggattggaaataatctttactggaccaatgatggccat aggaaaaccattaatgtggccaggctggaaaaagcttctcagagtcggaagactctttta gagggtgaaatgtctcatcccagaggaattgtggtggatccagttaatggttggatgtat tggacagactgggaggaagatgaaatagatgacagcgtgggaaggattgagaaggcctgg atggatggattcaatcggcagatttttgtgacttcaaagatgctgtggccaaacggttta actctggactttcacaccaacacattatactggtgtgatgcctattacgatcatattgaa aaagtatttttgaatgggactcacaggaagattgtttacagtgggagagagttgaaccac cctttcggactgtcgcatcatggaaattatgtgttctggactgattatatgaatggttcc atttttcaactagatttgataacaagtgaggtgacattgctgaggcatgaaagaccaccc ctatttgggcttcagatttatgatccacgaaagcaacaaggtgacaatatgtgccgagta aataatgggggctgtagtacactttgcttggctatcccaggaggccgggtgtgtgcttgt gccgataatcaacttttggatgaaaatgggacaacttgcacatttaatcctggagaagca ctacctcacatatgtaaagctggagagtttcgctgcaaaaacagacactgtatccaagct cggtggaaatgtgatggcgacgatgactgcctagacggaagcgatgaggattcagtaaac tgcttcaatcatagctgtcctgatgatcagtttaaatgccagaataatcgctgcatcccc aagagatggctttgtgatggagctaatgactgtgggagcaatgaagatgaatccaatcaa acttgcacagccagaacatgccaggtagaccagttttcttgcggaaatgggcgttgcatt cccagagcatggctgtgtgacagggaagacgactgtggtgaccagacagatgaaatggca tcttgtgaattcccaacttgtgagccactaacccaattcgtatgcaaaagtggaagatgc attagcagcaaatggcactgcgactctgatgacgactgtggggacgggagtgatgaggtg ggctgtgttcactcttgctttgataatcagttcagatgttccagtggcagatgcatccca ggccactgggcctgtgatggtgacaatgactgtggggacttcagtgatgaagcccagatc aattgtactaaagaagagattcattctcctgctggttgtaacggaaatgaatttcagtgc caccctgatggtaattgcgttcctgatttgtggcgctgtgatggagaaaaagactgtgaa gatggtagtgatgaaaaaggttgcaatggtaccatacgattgtgtgaccacaaaaccaag ttttcctgttggagtacagggagatgcatcaacaaagcatgggtgtgtgatggagatatt gattgcgaagatcagtcagatgaagatgactgtgacagtttcttgtgtggaccacccaag catccttgtgctaatgacacctcagtctgcctgcagccagagaaactctgcaatgggaaa aaggattgtcctgatggctctgatgaaggctatctctgtgatgagtgttcgctgaacaat ggaggctgtagcaaccactgttctgttgttcctggaagaggaattgtctgttcctgccct gaaggacttcaactcaacaaagacaataaaacatgtgaaattgtggattattgtagcaat catctaaagtgcagccaagtatgtgagcagcacaagcacacagtcaagtgctcatgttat gaaggttggaagctggatgtagacggtgaaagttgtacaagtgttgatccttttgaagca ttcatcatcttttctattcgtcatgagatcagaaggattgatcttcacaaaagagactat agtctacttgttcctggattgagaaacacaatagcacttgattttcacttcaatcaaagt ttactttattggacagatgttgtagaagacagaatataccggggaaagctttctgaaagt ggaggtgtcagtgccattgaagtggttgtggagcatggcctggctactccagaaggcctg acagtcgactggatagcaggaaacatatactggatagacagcaatctggaccaaatcgaa gtggccaaactagatggctccctaagaactacactaatagcaggagccatggaacacccc agggccattgctttggacccaagatatggaattcttttctggacagactgggatgcaaat tttcctcgcattgaatctgcctctatgagtggtgctgggagaaaaaccatctataaagac atgaaaactggggcttggcctaatggactaactgtggaccactttgagaaaaggatagtg tggacagacgccaggtcagatgctatttattcagccctctatgatggaacaaacatgata gaaatcatccgaggtcatgaatacctttcccatccctttgctgtgtctctatatgggagt gaagtctactggacagactggaggaccaacacattgtccaaagccaataagtggacaggg cagaatgtcagtgtgattcagaaaaccagtgcacagccatttgaccttcagatataccat cccagtcgccagccacaggctcccaatccttgtgcagctaatgatggcaaaggcccctgc tctcacatgtgtctaatcaatcacaataggagtgctgcctgtgcgtgcccccacttgatg aagctttcttcagacaagaagacctgctatgaaatgaaaaaatttcttctttatgcaaga cgttctgaaatcagaggagtggatattgacaatccatactttaacttcatcacggcattt acagtccctgatattgatgacgttactgtgatagacttcgatgcatctgaggaacgttta tactggacagatattaaaacacaaaccattaaacgagcttttattaacggaactgggtta gaaactgttatttcaagagatattcagagtatcagagggctagcagtggattgggtgtca cgtaatttatactggattagctcagaatttgatgaaacgcaaattaatgtggcaaggcta gatggctctttgaaaacctcaattatccatggaatcgataagccacagtgtcttgcagct cacccagtcaggggaaaactctactggaccgatggaaacacaattaacatggcaaatatg gatggcagtaatagcaagattctgtttcagaatcagaaggagccagttggtctatcgata gactatgtggaaaacaagctttattggatcagttcagggaatggaaccataaatagatgc aacctggatggtggtaatttagaagtaatcgagtcaatgaaagaagaattaacaaaagct acagccctaaccatcatggataagaaactgtggtgggcagaccaaaacttagcccagcta ggaacctgcagcaaaagagacggaagaaaccccaccatcctacggaataagacttctggg gtagttcatatgaaagtctatgataaagaagcacagcaaggcagcaattcctgccaacta aacaatggtggatgctctcaactttgtttaccaacatctgaaactacaaggacttgtatg tgtacagtgggatattatctccaaaagaaccgtatgtcatgtcaaggtatagaatcattt cttatgtactctgttcatgaaggaatcaggggaatacctcttgaaccaagtgacaaaatg gatgctttgatgcctatatcaggaacttcatttgccgtgggaatagatttccatgcagaa aatgataccatctactggacagacatgggcttcaataaaattagcagagctaaaagagat cagacttggaaagaagatatcattaccaatggcttgggaagagtggaagggatagctgtt gactggattgctggtaacatatattggacagatcatggtttcaacttaattgaagttgca agactcaatggttctttccgttatgtaattatttcccaaggcctggatcaaccaagatct atagctgtgcacccagagaaaggcctcttgttctggactgaatggggacaaatgccctgt attggaaaggctcgcttggatggctcagagaaggttgtccttgtaagcatgggaatagca tggccgaatggcatctccatcgactatgaggaaaataaattgtactggtgtgatgctcgc acagacaagatagagagaatcgaccttgagactggagggaatcgcgagatggtgctgtca ggaagcaatgtggatatgttttcagttgcagtctttggggcttacatctactggtctgac agagcacatgcaaacgggtctgtcagaaggggccacaagaatgatgccacagaaacgata accatgagaaccggccttggagtcaacctgaaggaggttaaaatatttaaccgagtaaga gagaaagggaccaatgtttgtgccagggacaatggtggctgtaagcaactctgtctttat cgaggaaattcccggagaacttgtgcttgtgcccatggatatttggcagaagatggagtt acttgcctgaggcatgaaggctatttactgtattcaggaagaacaatattaaaaagtata catctttctgatgaaaccaatttaaattccccaataaggccatatgagaatccacgttat ttcaagaatgtcatagccttggcttttgactataatcaaagaagaaaaggtaccaaccga atcttttacagtgatgcacactttggaaatatacagcttattaaagacaactgggaagac agacaagtaattgttgaaaatgtgggttctgtggaaggacttgcctatcacagagcctgg gatacactgtactggacaagctctaccacctcatccatcaccagacacactgtggaccag actcggcctggagcatttgacagggaagctgtcatcaccatgtcagaagatgaccatcca catgtgctagccttggatgaatgtcaaaatttaatgttttggaccaactggaatgaacaa catccaagtatcatgagatctactctgactgggaaaaatgctcaagtggtggtcagtaca gacatactcactccaaatggacttactatcgactaccgtgcagagaagctgtatttctca gatggcagtctaggaaaaattgaaaggtgtgaatacgatggatcccagagacatgtgata gttaaatctgggccagggactttcctcagtttggctgtttatgacaattatatattctgg tcggactggggaagaagagctatactgcggtccaacaagtacacaggaggagatacaaaa attcttcgttccgatattccacatcagccaatgggaatcatagctgttgccaatgacacc aatagctgtgaactttctccatgtgcattattgaatggaggctgccatgacttgtgcctt ttaactcccaatgggagagtgaattgttcctgcagaggggaccgaatattgctagaggac aacagatgtgtgactaaaaattcctcctgcaacgcttattcggagtttgaatgtggaaat ggtgagtgcattgactaccagctcacctgtgatggcattcctcactgtaaagataaatca gatgaaaaactgctctactgtgaaaacagaagctgtcgaagaggcttcaagccatgctat aatcgccgctgcattcctcatggcaagttatgtgatggagaaaatgactgcggagacaac tctgatgaattagattgtaaagtttcaacctgtgccacggttgagttccgctgtgcagat gggacttgtattccaagatcagcacgatgcaaccagaacatagattgtgcagatgcttca gatgaaaagaactgcaataacacagactgcacacatttctataagcttggagtgaaaacc acagggttcataagatgtaattctacctcactgtgtgttctgccaacctggatatgcgac gggtctaatgactgtggagactattcagatgaattaaagtgcccagttcaaaacaaacac aaatgtgaagaaaattattttagttgtcctagtggaagatgcattttgaatacctggata tgcgatggtcagaaagattgtgaggatggacgtgatgaattccactgtgattcttcttgc tcttggaaccaatttgcttgttccgcacaaaaatgtatttctaagcattggatttgtgat ggagaagatgactgtggggatgggttagatgaaagtgacagcatttgtggtgccataacc tgtgctgctgacatgttcagctgccagggctctcgtgcctgcgtgccccgacattggctt tgtgatggtgaaagggactgtccagatggaagcgatgagctttccacagcaggctgcgct cccaataatacatgtgatgaaaatgctttcatgtgccataataaagtatgcattcccaag caatttgtttgtgaccatgatgacgactgtggagatggctctgatgagtcaccgcagtgt ggatatcgacagtgtggtacagaagaatttagttgtgctgatgggcggtgtcttctaaat actcaatggcagtgtgatggagactttgactgtcctgaccattctgatgaagcaccttta aacccaaagtgtaaaagtgcagaacagtcatgcaacagttcattttttatgtgcaaaaat ggcaggtgcattcccagtggaggtctttgcgacaataaggatgactgtggcgatggttca gatgagagaaactgccatataaatgaatgtttgagtaagaaagtcagtggatgttctcaa gactgtcaagaccttccggtcagttataagtgcaaatgctggcctggattccaactgaag gatgacggcaaaacatgtgtagacattgatgaatgctcttcaggctttccctgtagccag caatgcatcaatacatacgggacttacaagtgcctctgtacagatgggtatgaaatacaa cctgataacccaaatggctgcaaatcgctctcagatgaagaaccttttttaattcttgct gatcatcatgagataaggaaaattagcactgatggctccaactacacacttttaaaacag ggattaaacaatgttattgctatagactttgattacagagaagaattcatctattggatc gattctagccgacccaatggcagtcgcataaatagaatgtgtttaaatggaagtgacatt aaggtagttcataacacagcggtccccaatgcacttgctgtcgattggattggaaaaaac ctctattggtctgacacagaaaaaagaatcattgaagtatccaaactcaatggcttgtac cctactatactcgttagcaaaaggctgaagtttcccagagacttgtctttagatcctcaa gctggatatttgtattggattgactgctgcgagtatcctcatattggccgtgttggaatg gatggaaccaatcagagtgttgtcatagaaaccaagatttctagacctatggcactaaca atagattatgttaatcgtagactctactgggccgatgaaaatcacattgaatttagcaac atggatggatctcatagacacaaagtccctaatcaagatattccaggggtgattgcacta acattgtttgaagactacatctactggactgatgggaaaaccaagtcactcagccgtgcc cataaaacatcgggagcagacagactctcactgatttactcatggcatgccatcacagat atccaggtgtatcattcttatagacaacctgatgtctccaaacatctctgcatgataaat aatggtggttgcagtcatttgtgccttttagcccctggaaaaacccacacttgtgcatgt cccactaacttctatctggcagctgataataggacttgcttatccaactgcacagccagc cagtttcgttgcaaaactgacaaatgtattccattctggtggaaatgtgacaccgtggat gactgtggtgatggatctgatgaacctgatgactgtcctgaatttagatgtcagccaggc cgatttcagtgtgggactggactctgtgctctaccagctttcatctgtgatggagagaat gattgtggagacaattctgatgaactcaactgtgacacacatgtctgcctgtcaggtcaa ttcaaatgtaccaagaaccagaaatgtatcccagtaaacttaagatgtaatgggcaagat gactgtggtgatgaggaagatgaaagagactgtcctgaaaacagctgttctccagactat ttccagtgtaagactacgaagcattgcatttccaagctgtgggtttgtgacgaggatcca gactgtgcagatgcatcagacgaggccaactgcgataaaaagacttgtggacctcatgaa ttccagtgtaaaaacaacaactgtattcccgatcactggcggtgtgatagccaaaatgac tgcagtgataattcagatgaagaaaactgtaagccacagacatgtacattgaaagatttc ctctgtgccaatggggactgtgtttcttcaaggttttggtgtgatggagattttgactgt gcagatggctctgatgagagaaattgtgagacaagttgttccaaagatcagttccggtgt tccaatggtcagtgtataccagcaaaatggaaatgtgatggccatgaagactgcaaatat ggggaagatgagaaaagctgtgagccagcttctcctacttgctcatcacgtgaatatata tgtgccagtgatggatgtatttcagcatctttgaaatgtaatggagaatatgattgtgct gatggttcagatgagatggactgtgtgactgaatgtaaggaagatcagtttcggtgcaaa aataaagcccactgtattccaattagatggctgtgtgatggaattcatgactgtgtggat ggcagtgatgaagagaactgtgaaagaggaggaaatatatgtagagctgatgagttcctt tgcaataattctctctgcaaactacatttctgggtgtgtgatggagaggacgactgtgga gacaactctgatgaagcccctgatatgtgtgtcaaatttctttgtccatccacgagacct cacagatgcagaaataacagaatatgcctacagtcggagcaaatgtgcaatgggattgat gaatgcggtgacaattcagatgaagatcactgtggtggtaagctgacatataaagcaagg ccttgtaaaaaggatgagtttgcttgtagtaataaaaaatgcatccctatggatctccag tgtgatcgacttgatgactgcggagatggttcagatgagcaaggatgcagaatagctcct actgaatatacctgtgaagataatgtgaatccatgtggagatgatgcatattgtaatcaa ataaaaacatctgttttctgtcgctgtaagcctggatttcagagaaacatgaaaaacaga caatgtgaagaccttaatgaatgtttggtgtttggcacatgttcccatcaatgtataaat gtggaaggatcatataaatgtgtgtgtgaccagaattttcaagaaagaaataacacctgc atagcagaaggctctgaagatcaagttctctacattgctaatgacactgatatcctgggt tttatatatccattcaactacagtggcgatcatcaacaaatttctcatattgaacataat tcaagaataacagggatggatgtatattatcaaagagatatgattatttggagtactcag tttaatccaggcggaattttctacaaaaggatccatggcagagaaaaaaggcaagcaaac agtggcttgatttgtcctgaatttaaaaggcccagggacattgcagttgactgggtggct ggaaacatttactggactgatcattctagaatgcattggttcagttactacactactcac tggaccagtctgaggtactctatcaacgtagggcagctgaatggccccaactgcaccaga ctcttaacaaatatggctggagaaccctatgctattgcagtaaatcctaaaagagggatg atgtactggactgttgttggggatcattcccatatagaagaagcagccatggatggtaca ctgagaaggattttagtacaaaagaacttacagagacccacaggtttggctgtggattat tttagtgaacgcatatattgggctgactttgagctctccatcattggcagtgttctgtat gatggctctaattcagtagtctctgtcagcagcaaacaaggtttattacatccacatagg atcgatatctttgaagattatatatatggagcaggacctaaaaatggtgtatttcgagtt caaaaatttggccatggttcagtagagtacttagctttaaatattgataaaacaaaaggt gttttgatatctcatcgttataaacaactagatttacccaatccatgcttggatttagca tgcgaatttctttgcttgctaaatccttctggggccacttgtgtgtgtccagaaggaaaa tatttgattaatggcacctgcaatgatgacagcctgttagatgattcatgtaagttaact tgtgaaaatggaggaagatgcattttaaatgagaaaggtgatttgaggtgtcactgttgg cccagttattcaggagaaagatgtgaagtcaaccactgtagcaactactgccagaatgga ggaacttgcgtaccatcagttctagggagacccacctgcagctgtgcactgggtttcact gggccaaactgtggtaagacagtctgtgaggatttttgtcaaaatggaggaacctgcatt gtgactgctggaaaccagccttactgccactgccagccggaatacaccggagacagatgt cagtactacgtgtgccaccactattgtgtgaattctgaatcatgtaccattggggatgat ggaagtgttgaatgtgtctgtccaacgcgctatgaaggaccaaaatgtgaggttgacaag tgtgtaaggtgccatggggggcactgcattataaataaagacagtgaagatatattttgc aactgcactaatggaaagattgcctctagctgtcagttatgtgatggctactgttacaat ggtggcacatgccagctggaccccgagacaaatgtacctgtgtgtctatgctccaccaac tggtcaggcacacagtgtgaaaggccagccccaaagagcagcaagtctgatcatatcagc acaagaagcattgccatcattgtgcctctcgtcctcttggtgactttgataaccacctta gtaattggtttagtgctttgtaaaagaaaaagaaggacaaaaacaattagaagacaacct attatcaatggaggaataaatgtagaaattggcaatccatcttataacatgtatgaggta gatcatgatcacaacgatggaggtcttttagatcctggctttatgatagacccaacaaag gccaggtacatagggggaggacccagtgctttcaagcttccacacacagcgccgcccatc tacctaaactctgatttgaaaggaccactaactgctgggccaacaaattactccaatccg gtatatgcaaaattatatatggatgggcaaaactgtcgaaactccttaggaagtgttgat gaaaggaaagaactgcttccaaagaaaatagaaattggtataagagagacagtggcataa

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