Homo sapiens (human): 53905
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Entry
53905 CDS
T01001
Symbol
DUOX1, LNOX1, NOXEF1, THOX1
Name
(RefSeq) dual oxidase 1
KO
K13411
dual oxidase [EC:
1.6.3.1
1.11.1.-]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04918
Thyroid hormone synthesis
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09152 Endocrine system
04918 Thyroid hormone synthesis
53905 (DUOX1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
53905 (DUOX1)
Enzymes [BR:
hsa01000
]
1. Oxidoreductases
1.6 Acting on NADH or NADPH
1.6.3 With oxygen as acceptor
1.6.3.1 NAD(P)H oxidase (H2O2-forming)
53905 (DUOX1)
Membrane trafficking [BR:
hsa04131
]
Others
NADPH oxidases (Nox) and associated proteins
NADPH oxidases
53905 (DUOX1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
An_peroxidase
NAD_binding_6
FAD_binding_8
EF-hand_1
Ferric_reduct
EF-hand_7
EF-hand_8
EF-hand_6
EF-hand_5
NAD_binding_1
Rv0078B
Motif
Other DBs
NCBI-GeneID:
53905
NCBI-ProteinID:
NP_059130
OMIM:
606758
HGNC:
3062
Ensembl:
ENSG00000137857
UniProt:
Q9NRD9
Structure
PDB
PDBj
LinkDB
All DBs
Position
15:45129994..45165574
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AA seq
1551 aa
AA seq
DB search
MGFCLALAWTLLVGAWTPLGAQNPISWEVQRFDGWYNNLMEHRWGSKGSRLQRLVPASYA
DGVYQPLGEPHLPNPRDLSNTISRGPAGLASLRNRTVLGVFFGYHVLSDLVSVETPGCPA
EFLNIRIPPGDPMFDPDQRGDVVLPFQRSRWDPETGRSPSNPRDPANQVTGWLDGSAIYG
SSHSWSDALRSFSRGQLASGPDPAFPRDSQNPLLMWAAPDPATGQNGPRGLYAFGAERGN
REPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAVYEWLPSFL
QKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVPPGVYMRNASCHFQGVINRNSSVSRA
LRVCNSYWSREHPSLQSAEDVDALLLGMASQIAEREDHVLVEDVRDFWPGPLKFSRTDHL
ASCLQRGRDLGLPSYTKARAALGLSPITRWQDINPALSRSNDTVLEATAALYNQDLSWLE
LLPGGLLESHRDPGPLFSTIVLEQFVRLRDGDRYWFENTRNGLFSKKEIEEIRNTTLQDV
LVAVINIDPSALQPNVFVWHKGDPCPQPRQLSTEGLPACAPSVVRDYFEGSGFGFGVTIG
TLCCFPLVSLLSAWIVARLRMRNFKRLQGQDRQSIVSEKLVGGMEALEWQGHKEPCRPVL
VYLQPGQIRVVDGRLTVLRTIQLQPPQKVNFVLSSNRGRRTLLLKIPKEYDLVLLFNLEE
ERQALVENLRGALKESGLSIQEWELREQELMRAAVTREQRRHLLETFFRHLFSQVLDINQ
ADAGTLPLDSSQKVREALTCELSRAEFAESLGLKPQDMFVESMFSLADKDGNGYLSFREF
LDILVVFMKGSPEEKSRLMFRMYDFDGNGLISKDEFIRMLRSFIEISNNCLSKAQLAEVV
ESMFRESGFQDKEELTWEDFHFMLRDHNSELRFTQLCVKGVEVPEVIKDLCRRASYISQD
MICPSPRVSARCSRSDIETELTPQRLQCPMDTDPPQEIRRRFGKKVTSFQPLLFTEAHRE
KFQRSCLHQTVQQFKRFIENYRRHIGCVAVFYAIAGGLFLERAYYYAFAAHHTGITDTTR
VGIILSRGTAASISFMFSYILLTMCRNLITFLRETFLNRYVPFDAAVDFHRLIASTAIVL
TVLHSVGHVVNVYLFSISPLSVLSCLFPGLFHDDGSELPQKYYWWFFQTVPGLTGVVLLL
ILAIMYVFASHHFRRRSFRGFWLTHHLYILLYVLLIIHGSFALIQLPRFHIFFLVPAIIY
GGDKLVSLSRKKVEISVVKAELLPSGVTHLRFQRPQGFEYKSGQWVRIACLALGTTEYHP
FTLTSAPHEDTLSLHIRAAGPWTTRLREIYSAPTGDRCARYPKLYLDGPFGEGHQEWHKF
EVSVLVGGGIGVTPFASILKDLVFKSSVSCQVFCKKIYFIWVTRTQRQFEWLADIIREVE
ENDHQDLVSVHIYITQLAEKFDLRTTMLYICERHFQKVLNRSLFTGLRSITHFGRPPFEP
FFNSLQEVHPQVRKIGVFSCGPPGMTKNVEKACQLINRQDRTHFSHHYENF
NT seq
4656 nt
NT seq
+upstream
nt +downstream
nt
atgggcttctgcctggctctagcatggacacttctggttggggcatggacccctctggga
gctcagaaccccatttcgtgggaggtgcagcgatttgatgggtggtacaacaacctcatg
gagcacagatggggcagcaaaggctcccggctgcagcgcctggtcccagccagctatgca
gatggcgtgtaccagcccttgggagaaccccacctgcccaacccccgagaccttagcaac
accatctcaaggggccctgcagggctggcctccctgagaaaccgcacagtgttgggggtc
ttctttggctatcacgtgctttcagacctggtgagcgtggaaactcccggctgccccgcc
gagttcctcaacattcgcatcccgcccggagaccccatgttcgaccccgaccagcgcggg
gacgtggtgctgcccttccagagaagccgctgggaccccgagaccggacggagtcccagc
aatccccgggacccggccaaccaggtgacgggctggctggacggcagcgccatctatggt
tcctcgcattcctggagcgacgcgctgcggagcttctccaggggacagctggcgtcgggg
cccgaccccgcttttccccgagactcgcagaaccccctgctcatgtgggcggcgcccgac
cccgccaccgggcagaacgggccccgggggctgtacgccttcggggcagagagagggaac
cgggaacccttcctgcaggcgctgggcctgctctggttccgctaccacaacctgtgggcg
cagaggctggcccgccagcacccagactgggaggacgaggagctgttccagcacgcacgc
aagagggtcatcgccacctaccagaacatcgctgtgtatgagtggctgcccagcttcctg
cagaaaacactcccggagtatacaggataccggccatttctggaccccagcatctcctca
gagttcgtggcggcctctgagcagttcctgtccaccatggtgccccctggcgtctacatg
agaaatgccagctgccacttccagggggtcatcaatcggaactcaagtgtctccagagct
ctccgggtctgcaacagctactggagccgtgagcacccaagcctacaaagtgctgaagat
gtggatgcactgctgctgggcatggcctcccagatcgcagagcgagaggaccatgtgttg
gttgaagatgtgcgggatttctggcctgggccactgaagttttcccgcacagaccacctg
gccagctgcctgcagcggggccgggatctgggcctgccctcttacaccaaggccagggca
gcactgggcttgtctcccattacccgctggcaggacatcaaccctgcactctcccggagc
aatgacactgtactggaggccacagctgccctgtacaaccaggacttatcctggctagag
ctgctccctgggggactcctggagagccaccgggaccctggacctctgttcagcaccatc
gtccttgaacaatttgtgcggctacgggatggtgaccgctactggtttgagaacaccagg
aatgggctgttctccaagaaggagattgaagaaatccgaaataccaccctgcaggacgtg
ctggtcgctgttatcaacattgaccccagtgctctgcagcccaatgtctttgtctggcat
aaaggagacccctgtccgcagccgagacagctcagcactgaaggcctgccagcgtgtgct
ccctctgttgttcgtgactattttgagggcagtggatttggcttcggggtcaccatcggg
accctctgttgcttccctttggtgagcctgctcagtgcctggattgttgcccggctccgg
atgagaaatttcaagaggctccagggccaggaccgccagagcatcgtgtctgagaagctc
gtgggaggcatggaagctttggaatggcaaggccacaaggagccctgccggcccgtgctt
gtgtacctgcagcccgggcagatccgtgtggtagatggcaggctcaccgtgctccgcacc
atccagctgcagcctccacagaaggtcaacttcgtcctgtccagcaaccgtggacgccgc
actctgctgctcaagatccccaaggagtatgacctggtgctgctgtttaacttggaggaa
gagcggcaggcgctggtggaaaatctccggggagctctgaaggagagcgggttgagcatc
caggagtgggagctgcgggagcaggagctgatgagagcagctgtgacacgggagcagcgg
aggcacctcctggagacctttttcaggcaccttttctcccaggtgctggacatcaaccag
gccgacgcagggaccctgcccctggactcctcccagaaggtgcgggaggccctgacctgt
gagctgagcagggccgagtttgccgagtccctgggcctcaagccccaggacatgtttgtg
gagtccatgttctctctggctgacaaggatggcaatggctacctgtccttccgagagttc
ctggacatcctggtggtcttcatgaaaggctctcctgaggaaaagtctcgccttatgttc
cgcatgtacgactttgatgggaatggcctcatttccaaggatgagttcatcaggatgctg
agatccttcatcgagatctccaacaactgcctgtccaaggcccagctggctgaggtggtg
gagtccatgttccgggagtcgggattccaggacaaggaggaactgacatgggaagatttt
cacttcatgctgcgggaccacaatagcgagctccgcttcacgcagctctgtgtcaaaggg
gtggaggtgcctgaagtcatcaaggacctctgccggcgagcctcctacatcagccaggat
atgatctgtccctctcccagagtgagtgcccgctgttcccgcagcgacattgagactgag
ttgacacctcagagactgcagtgccccatggacacagaccctccccaggagattcggcgg
aggtttggcaagaaggtaacgtcattccagcccttgctgttcactgaggcgcaccgagag
aagttccaacgcagctgtctccaccagacggtgcaacagttcaagcgcttcattgagaac
taccggcgccacatcggctgcgtggccgtgttctacgccatcgctggggggcttttcctg
gagagggcctactactacgcctttgccgcacatcacacgggcatcacagacaccacccgc
gtgggaatcatcctgtcgcggggcacagcagccagcatctctttcatgttctcctacatc
ttgctcaccatgtgccgcaacctcatcaccttcctgcgagaaaccttcctcaaccgctac
gtgcccttcgacgccgccgtggacttccatcgcctcattgcctccaccgccatcgtcctc
acagtcttacacagtgtgggccatgtggtgaatgtgtacctgttctccatcagccccctc
agcgtcctctcttgcctctttcctggcctcttccatgatgatgggtctgagctcccccag
aagtattactggtggttcttccagaccgtaccaggcctcacgggggttgtgctgctcctg
atcctggccatcatgtatgtctttgcctcccaccacttccgccgccgcagtttccggggc
ttctggctgacccaccacctctacatcctgctctatgtcctgctcatcatccatggtagc
tttgccctgatccagctgccccgtttccacatcttcttcctggtcccagcaatcatctat
gggggcgacaagctggtgagcctgagccggaagaaggtggagatcagcgtggtgaaggcg
gagctgctgccctcaggagtgacccacctgcggttccagcggccccagggctttgagtac
aagtcagggcagtgggtgcggatcgcttgcctggctctggggaccaccgagtaccacccc
ttcacactgacctctgcgccccatgaggacacgcttagcctgcacatccgggcagcaggg
ccctggaccactcgcctcagggagatctactcagccccgacgggtgacagatgtgccaga
tacccaaagctgtaccttgatggaccatttggagagggccaccaggagtggcataagttt
gaggtgtcagtgttagtgggagggggcattggggtcaccccttttgcctccatcctcaaa
gacctggtcttcaagtcatccgtcagctgccaagtgttctgtaagaagatctacttcatc
tgggtgacgcggacccagcgtcagtttgagtggctggctgacatcatccgagaggtggag
gagaatgaccaccaggacctggtgtctgtgcacatctacatcacccagctggctgagaag
ttcgacctcaggaccactatgctgtacatctgtgagcggcacttccagaaggttctgaac
cggagtctattcacaggcctgcgctccatcacccactttggccgtcccccctttgagccc
ttcttcaactccctgcaggaggtccacccccaggtccggaagatcggggtgtttagctgt
ggcccccctggcatgaccaagaatgtggaaaaggcctgtcagctcatcaacaggcaggac
cggactcacttctcccaccattatgagaacttctag
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integrated database retrieval system
