Homo sapiens (human): 53981
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Entry
53981 CDS
T01001
Symbol
CPSF2, CPSF100
Name
(RefSeq) cleavage and polyadenylation specific factor 2
KO
K14402
cleavage and polyadenylation specificity factor subunit 2
Organism
hsa
Homo sapiens (human)
Pathway
hsa03015
mRNA surveillance pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09122 Translation
03015 mRNA surveillance pathway
53981 (CPSF2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
hsa03019
]
53981 (CPSF2)
Messenger RNA biogenesis [BR:
hsa03019
]
Eukaryotic type
mRNA processing factors
3' end processing
Cleavage and polyadenylation specificity factor (CPSF) complex
53981 (CPSF2)
U7-dependent histone pre-mRNA processing factors
53981 (CPSF2)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Lactamase_B_6
CPSF100_C
Beta-Casp
RMMBL
Lactamase_B
Lactamase_B_2
Beta_lactamase3
Motif
Other DBs
NCBI-GeneID:
53981
NCBI-ProteinID:
NP_001309201
OMIM:
606028
HGNC:
2325
Ensembl:
ENSG00000165934
UniProt:
Q9P2I0
Structure
PDB
PDBj
LinkDB
All DBs
Position
14:92121969..92172145
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AA seq
782 aa
AA seq
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MTSIIKLTTLSGVQEESALCYLLQVDEFRFLLDCGWDEHFSMDIIDSLRKHVHQIDAVLL
SHPDPLHLGALPYAVGKLGLNCAIYATIPVYKMGQMFMYDLYQSRHNTEDFTLFTLDDVD
AAFDKIQQLKFSQIVNLKGKGHGLSITPLPAGHMIGGTIWKIVKDGEEEIVYAVDFNHKR
EIHLNGCSLEMLSRPSLLITDSFNATYVQPRRKQRDEQLLTNVLETLRGDGNVLIAVDTA
GRVLELAQLLDQIWRTKDAGLGVYSLALLNNVSYNVVEFSKSQVEWMSDKLMRCFEDKRN
NPFQFRHLSLCHGLSDLARVPSPKVVLASQPDLECGFSRDLFIQWCQDPKNSIILTYRTT
PGTLARFLIDNPSEKITEIELRKRVKLEGKELEEYLEKEKLKKEAAKKLEQSKEADIDSS
DESDIEEDIDQPSAHKTKHDLMMKGEGSRKGSFFKQAKKSYPMFPAPEERIKWDEYGEII
KPEDFLVPELQATEEEKSKLESGLTNGDEPMDQDLSDVPTKCISTTESIEIKARVTYIDY
EGRSDGDSIKKIINQMKPRQLIIVHGPPEASQDLAECCRAFGGKDIKVYMPKLHETVDAT
SETHIYQVRLKDSLVSSLQFCKAKDAELAWIDGVLDMRVSKVDTGVILEEGELKDDGEDS
EMQVEAPSDSSVIAQQKAMKSLFGDDEKETGEESEIIPTLEPLPPHEVPGHQSVFMNEPR
LSDFKQVLLREGIQAEFVGGVLVCNNQVAVRRTETGRIGLEGCLCQDFYRIRDLLYEQYA
IV
NT seq
2349 nt
NT seq
+upstream
nt +downstream
nt
atgacgtctattatcaaattaactaccctttctggggtccaagaagaatctgccctttgc
tatcttctccaagttgatgagtttagatttttattggactgtggctgggatgagcacttt
tctatggatattattgattccctgaggaagcatgttcaccagattgatgcagtgctgttg
tctcaccctgatcctctccaccttggtgccctcccgtatgctgtcggaaagttgggtctg
aactgtgctatctatgcaaccattcctgtttataaaatgggacagatgttcatgtatgat
ctttatcagtctcgacacaatacagaagattttacactctttacattagatgatgtggat
gcagcctttgataaaatacagcagctaaaattctctcagattgtgaatttgaaaggtaaa
ggacatggcctgtctatcacacctctgccagctggtcatatgataggtggaacaatatgg
aaaatagtcaaagatggagaagaagaaattgtttatgcagttgacttcaaccacaagagg
gagatccatttaaatggatgttccctggaaatgctaagcaggccttccctacttatcaca
gattcattcaatgctacatatgtacagcctagaagaaaacagagagatgagcagcttctg
acaaatgtcctggaaacacttcgaggtgatggaaatgtgttaatagcagtggacacagca
ggcagagttttggaacttgctcaacttcttgatcagatttggaggactaaagatgcagga
ttgggtgtttactcattggcactcctaaataatgtcagttacaatgtggtggagttttct
aagtcccaggtagaatggatgagtgataaattgatgagatgttttgaagacaaaagaaat
aatccgtttcagtttcgccatctctctttatgtcatggtctttctgacttggcccgtgta
cctagccctaaagttgtacttgccagccaacctgacctggaatgcggattttcaagggat
ctctttattcagtggtgtcaggaccctaaaaactcaatcattctaacctacagaactact
cctgggactttagcacgtttcctaattgataatccttctgaaaaaattacagaaatagag
ttgaggaaacgtgtgaagcttgaagggaaagaacttgaagaatacttggaaaaagagaaa
ctaaagaaagaagctgccaaaaagcttgagcagtcaaaagaggcagatatagattccagt
gatgagagtgatattgaggaagatattgaccagccatcagctcataagacgaagcatgac
ttgatgatgaaaggtgaaggcagtcgtaaaggaagttttttcaaacaggcaaaaaagtcc
tatcctatgtttcctgccccagaagaaagaattaaatgggatgaatatggagagattatc
aaaccagaggatttcttagtgccagagcttcaagctactgaagaagaaaaaagcaaatta
gaatctggtttgacaaatggagatgaacctatggatcaggatttatctgatgttcctact
aaatgtatttctacaacagagtctattgaaataaaagcccgggttacctacatagactat
gaaggacgctctgatggggattccattaaaaaaatcattaatcagatgaaaccacgacag
ttgatcatcgtccatggcccaccagaggccagtcaagatctggcagagtgctgtcgcgcc
tttggtgggaaagatattaaagtgtacatgccaaagctacatgaaacagttgatgccact
agtgaaactcacatctaccaggtgaggttaaaagactcacttgtcagctctcttcagttt
tgtaaggcaaaagatgctgaattagcttggatagatggtgtcttagatatgagagtttcc
aaagtggacacaggggttattttagaagaaggagaactaaaggatgatggagaagactca
gagatgcaagtggaagctccctcagattctagcgttatagcacaacaaaaggccatgaaa
agtctgttcggagatgatgaaaaagaaacaggtgaagaaagtgagatcattcctactttg
gaacccttgccacctcatgaggttcctggacatcagtcagtttttatgaatgaaccaagg
ctgtcagacttcaagcaagttctcttacgggaggggattcaagctgaatttgtaggaggt
gtacttgtttgcaacaatcaagtagcagtccgcagaacggaaactggacgcattggatta
gaaggctgcctttgtcaagatttttataggataagagaccttttatatgaacaatatgcc
attgtataa
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