Homo sapiens (human): 5408
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Entry
5408 CDS
T01001
Symbol
PNLIPRP2, PLRP2
Name
(RefSeq) pancreatic lipase related protein 2 (gene/pseudogene)
KO
K14075
pancreatic lipase-related protein 2 [EC:
3.1.1.3
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00561
Glycerolipid metabolism
hsa01100
Metabolic pathways
hsa04972
Pancreatic secretion
hsa04975
Fat digestion and absorption
Module
hsa_M00098
Acylglycerol degradation
Drug target
Orlistat:
D04028
<US>
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09103 Lipid metabolism
00561 Glycerolipid metabolism
5408 (PNLIPRP2)
09150 Organismal Systems
09154 Digestive system
04972 Pancreatic secretion
5408 (PNLIPRP2)
04975 Fat digestion and absorption
5408 (PNLIPRP2)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.1 Carboxylic-ester hydrolases
3.1.1.3 triacylglycerol lipase
5408 (PNLIPRP2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Lipase
PLAT
Abhydrolase_6
Abhydrolase_1
Retrotran_gag_3
Ser_hydrolase
BD-FAE
Abhydrolase_3
Hydrolase_4
Motif
Other DBs
NCBI-GeneID:
5408
NCBI-ProteinID:
NP_005387
OMIM:
604423
HGNC:
9157
Ensembl:
ENSG00000266200
UniProt:
P54317
Structure
PDB
PDBj
LinkDB
All DBs
Position
10:116620953..116645143
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AA seq
469 aa
AA seq
DB search
MLPPWTLGLLLLATVRGKEVCYGQLGCFSDEKPWAGTLQRPVKLLPWSPEDIDTRFLLYT
NENPNNFQLITGTEPDTIEASNFQLDRKTRFIIHGFLDKAEDSWPSDMCKKMFEVEKVNC
ICVDWRHGSRAMYTQAVQNIRVVGAETAFLIQALSTQLGYSLEDVHVIGHSLGAHTAAEA
GRRLGGRVGRITGLDPAGPCFQDEPEEVRLDPSDAVFVDVIHTDSSPIVPSLGFGMSQKV
GHLDFFPNGGKEMPGCKKNVLSTITDIDGIWEGIGGFVSCNHLRSFEYYSSSVLNPDGFL
GYPCASYDEFQESKCFPCPAEGCPKMGHYADQFKGKTSAVEQTFFLNTGESGNFTSWRYK
VSVTLSGKEKVNGYIRIALYGSNENSKQYEIFKGSLKPDASHTCAIDVDFNVGKIQKVKF
LWNKRGINLSEPKLGASQITVQSGEDGTEYNFCSSDTVEENVLQSLYPC
NT seq
1410 nt
NT seq
+upstream
nt +downstream
nt
atgctgcccccttggaccctcggccttctcctgctggccacagtcagaggaaaagaggtc
tgctacggacaacttggctgcttttctgatgaaaaaccatgggcaggaacccttcagcga
cctgtaaaattacttccctggtcccccgaggacattgacacccgctttcttctgtacaca
aatgaaaatccaaacaacttccaactaatcactggcacggaaccagacaccattgaggct
tcaaacttccaactggaccgcaagacacgcttcatcatccatggcttcttagacaaggcg
gaggacagctggccatcggacatgtgcaagaaaatgtttgaagtggagaaggtgaactgc
atctgtgtggactggaggcacgggtcccgggcaatgtacacccaagccgtgcaaaacatt
cgggttgttggggcggagacagctttcttaatacaagcactgtcgacgcagctagggtac
agccttgaggacgtgcatgtcatcggccacagcctgggcgcgcacacggccgcggaggcg
ggcaggaggctggggggccgcgtgggcaggatcacagggctggatccagcagggccgtgc
ttccaggatgaacctgaggaggttcggttggatccatctgacgccgtgtttgtggatgtg
attcacacagattcttctcccatagttccttccctaggtttcggaatgagccaaaaggtg
ggccatctggatttctttccaaatggaggaaaggaaatgcccggatgtaagaaaaatgtc
ctttcaaccattactgatattgatggaatatgggaaggaattggtggctttgtgtcttgc
aatcacctaagaagcttcgagtattactcaagcagcgtcctcaaccctgatggcttcctg
ggctatccctgtgcctcctacgatgagtttcaggagagtaagtgtttcccttgtccagct
gaaggatgccccaaaatggggcactatgctgaccaatttaaggggaaaacaagtgctgtg
gaacaaacctttttcctgaacacaggagagagtggtaactttactagttggagatataag
gtatcagtcacactttctggaaaagagaaagtgaatgggtacatcaggattgctttgtat
ggaagtaatgaaaactcaaaacaatatgagattttcaaaggatccctcaaaccagatgca
agtcacacgtgtgctattgatgtggattttaatgttggaaaaatacagaaagttaaattc
ctctggaacaaacgtgggataaatctatctgagcccaaactgggggcttcccaaatcaca
gtgcaaagtggtgaagatgggactgagtataatttttgtagcagcgacactgtggaagaa
aacgtcttgcaatctctttacccttgttaa
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