Homo sapiens (human): 5495
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Entry
5495 CDS
T01001
Symbol
PPM1B, PP2C-beta, PP2C-beta-X, PP2CB, PP2CBETA, PPC2BETAX
Name
(RefSeq) protein phosphatase, Mg2+/Mn2+ dependent 1B
KO
K04461
protein phosphatase 1B [EC:
3.1.3.16
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04010
MAPK signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
hsa01009
]
5495 (PPM1B)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.16 protein-serine/threonine phosphatase
5495 (PPM1B)
Protein phosphatases and associated proteins [BR:
hsa01009
]
Protein serine/threonine phosphatases
Mg2+- or Mn2+- dependent protein phosphatases (PPMs)
PPM1 phosphatases (PP2C)
5495 (PPM1B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PP2C
PP2C_C
PP2C_2
DUF3456
Motif
Other DBs
NCBI-GeneID:
5495
NCBI-ProteinID:
NP_002697
OMIM:
603770
HGNC:
9276
Ensembl:
ENSG00000138032
UniProt:
O75688
Structure
PDB
PDBj
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All DBs
Position
2:44168875..44246928
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AA seq
479 aa
AA seq
DB search
MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD
GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF
SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI
QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIIL
ACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPK
VSDEAVKKDSELDKHLESRVEEIMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGKR
NVIEAVYSRLNPHRESDGASDEAEESGSQGKLVEALRQMRINHRGNYRQLLEEMLTSYRL
AKVEGEESPAEPAATATSSNSDAGNPVTMQESHTESESGLAELDSSNEDAGTKMSGEKI
NT seq
1440 nt
NT seq
+upstream
nt +downstream
nt
atgggtgcatttttggataaacccaaaactgaaaaacataatgctcatggtgctgggaat
ggtttacgttatggcctgagcagcatgcaaggatggagagtggaaatggaagatgcacac
acagctgttgtaggtattcctcacggcttggaagactggtcattttttgcagtttatgat
ggtcatgctggatcccgagtggcaaattactgctcaacacatttattagaacacatcact
actaacgaagactttagggcagctggaaaatcaggatctgctcttgagctttcagtggaa
aatgttaagaatggtatcagaactggatttttgaaaattgatgaatacatgcgtaacttt
tcagacctcagaaacgggatggacaggagtggttcaactgcagtgggagttatgatttca
cctaagcatatctactttatcaactgtggtgattcacgtgctgttctgtataggaatgga
caagtctgcttttctacccaggatcacaaaccttgcaatccaagggaaaaggagcgaatc
caaaatgcaggaggcagcgtgatgatacaacgtgttaatggttcattagcagtatctcgt
gctctgggggactatgattacaagtgtgttgatggcaagggcccaacagaacaacttgtt
tctccagagcctgaggtttatgaaattttaagagcagaagaggatgaatttatcatcttg
gcttgtgatgggatctgggatgttatgagtaatgaggagctctgtgaatatgttaaatct
aggcttgaggtatctgatgacctggaaaatgtgtgcaattgggtagtggacacttgttta
cacaagggaagtcgagataacatgagtattgtactagtttgcttttcaaatgctcccaag
gtctcagatgaagcggtgaaaaaagattcagagttggataagcacttggaatcacgggtt
gaagagattatggagaagtctggcgaggaaggaatgcctgatcttgcccatgtcatgcgc
atcttgtctgcagaaaatatcccaaatttgcctcctgggggaggtcttgctggcaagcgt
aatgttattgaagctgtttatagtagactgaatccacatagagaaagtgatggggcctcc
gatgaagcagaggaaagtggatcacagggaaaattggtggaagctctcaggcaaatgaga
attaatcataggggaaactaccgacaacttctggaggagatgctgactagttacaggcta
gctaaagtagagggagaagaaagccctgctgaaccagctgccacagctacttcttcgaac
agtgatgctggaaacccagtgacaatgcaggaaagccatactgaatcagaaagtggtctt
gctgaattagacagctctaatgaagatgcagggacaaagatgagtggtgaaaaaatatga
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