Homo sapiens (human): 5498 Help Entry 5498              CDS       T01001                                  Symbol PPOX, PPO, V290M, VP, VPCO Name (RefSeq) protoporphyrinogen oxidase   KO K00231   protoporphyrinogen/coproporphyrinogen III oxidase [EC:1.3.3.4 1.3.3.15] Organism hsa  Homo sapiens (human) Pathway hsa00860   Porphyrin metabolism hsa01100   Metabolic pathways hsa01240   Biosynthesis of cofactors Module hsa_M00868   Heme biosynthesis, animals and fungi, glycine => heme Network nt06011  Heme biosynthesis   Element N00601   Heme biosynthesis Disease H00202   Hepatic porphyria H01763   Porphyria Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09108 Metabolism of cofactors and vitamins    00860 Porphyrin metabolism     5498 (PPOX) Enzymes [BR:hsa01000]  1. Oxidoreductases   1.3  Acting on the CH-CH group of donors    1.3.3  With oxygen as acceptor     1.3.3.4  protoporphyrinogen oxidase      5498 (PPOX)     1.3.3.15  coproporphyrinogen III oxidase (coproporphyrin-forming)      5498 (PPOX) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Amino_oxidase NAD_binding_8 DAO FAD_oxidored Thi4 Pyr_redox_2 FAD_binding_2 Motif Other DBs NCBI-GeneID:  5498 NCBI-ProteinID:  NP_000300 OMIM:  600923 HGNC:  9280 Ensembl:  ENSG00000143224 UniProt:  P50336 Structure PDBPDBj LinkDB All DBs Position 1:161165728..161178013 Genome browser AA seq 477 aa AA seqDB search MGRTVVVLGGGISGLAASYHLSRAPCPPKVVLVESSERLGGWIRSVRGPNGAIFELGPRG IRPAGALGARTLLLVSELGLDSEVLPVRGDHPAAQNRFLYVGGALHALPTGLRGLLRPSP PFSKPLFWAGLRELTKPRGKEPDETVHSFAQRRLGPEVASLAMDSLCRGVFAGNSRELSI RSCFPSLFQAEQTHRSILLGLLLGAGRTPQPDSALIRQALAERWSQWSLRGGLEMLPQAL ETHLTSRGVSVLRGQPVCGLSLQAEGRWKVSLRDSSLEADHVISAIPASVLSELLPAEAA PLARALSAITAVSVAVVNLQYQGAHLPVQGFGHLVPSSEDPGVLGIVYDSVAFPEQDGSP PGLRVTVMLGGSWLQTLEASGCVLSQELFQQRAQEAAATQLGLKEMPSHCLVHLHKNCIP QYTLGHWQKLESARQFLTAHRLPLTLAGASYEGVAVNDCIESGRQAAVSVLGTEPNS NT seq 1434 nt NT seq  +upstreamnt  +downstreamnt atgggccggaccgtggtcgtgctgggcggaggcatcagcggcttggccgccagttaccac ctgagccgggccccctgcccccctaaggtggtcctagtggagagcagtgagcgtctggga ggctggattcgctccgttcgaggccctaatggtgctatctttgagcttggacctcgggga attaggccagcgggagccctaggggcccggaccttgctcctggtttctgagcttggcttg gattcagaagtgctgcctgtccggggagaccacccagctgcccagaacaggttcctctac gtgggcggtgccctgcatgccctacccactggcctcagggggctactccgcccttcaccc cccttctccaaacctctgttttgggctgggctgagggagctgaccaagccccggggcaaa gagcctgatgagactgtgcacagttttgcccagcgccgccttggacctgaggtggcgtct ctagccatggacagtctctgccgtggagtgtttgcaggcaacagccgtgagctcagcatc aggtcctgctttcccagtctcttccaagctgagcaaacccatcgttccatattactgggc ctgctgctgggggcagggcggaccccacagccagactcagcactcattcgccaggccttg gctgagcgctggagccagtggtcacttcgtggaggtctagagatgttgcctcaggccctt gaaacccacctgactagtaggggggtcagtgttctcagaggccagccggtctgtgggctc agcctccaggcagaagggcgctggaaggtatctctaagggacagcagtctggaggctgac cacgttattagtgccattccagcttcagtgctcagtgagctgctccctgctgaggctgcc cctctggctcgtgccctgagtgccatcactgcagtgtctgtagctgtggtgaatctgcag taccaaggagcccatctgcctgtccagggatttggacatttggtgccatcttcagaagat ccaggagtcctgggaatcgtgtatgactcagttgctttccctgagcaggacgggagcccc cctggcctcagagtgactgtgatgctgggaggttcctggttacagacactggaggctagt ggctgtgtcttatctcaggagctgtttcaacagcgggcccaggaagcagctgctacacaa ttaggactgaaggagatgccgagccactgcttggtccatctacacaagaactgcattccc cagtatacactaggtcactggcaaaaactagagtcagctaggcaattcctgactgctcac aggttgcccctgactctggctggagcctcctatgagggagttgctgttaatgactgtata gagagtgggcgccaggcagcagtcagtgtcctgggcacagaacctaacagctga

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