Homo sapiens (human): 55144
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Entry
55144 CDS
T01001
Symbol
LRRC8D, HsLRRC8D, LRRC5
Name
(RefSeq) leucine rich repeat containing 8 VRAC subunit D
KO
K22038
volume-regulated anion channel
Organism
hsa
Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
hsa04040
]
55144 (LRRC8D)
Ion channels [BR:
hsa04040
]
Chloride channels
Chloride channel, volume-regulated (VRAC)
55144 (LRRC8D)
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Gene cluster
GFIT
Motif
Pfam:
Pannexin_like
LRR_4
LRR_8
LRR_9
LRR_5
Motif
Other DBs
NCBI-GeneID:
55144
NCBI-ProteinID:
NP_001127951
OMIM:
612890
HGNC:
16992
Ensembl:
ENSG00000171492
UniProt:
Q7L1W4
B3KRU1
Structure
PDB
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All DBs
Position
1:89821032..89936611
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AA seq
858 aa
AA seq
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MFTLAEVASLNDIQPTYRILKPWWDVFMDYLAVVMLMVAIFAGTMQLTKDQVVCLPVLPS
PVNSKAHTPPGNAEVTTNIPKMEAATNQDQDGRTTNDISFGTSAVTPDIPLRATYPRTDF
ALPNQEAKKEKKDPTGRKTNLDFQQYVFINQMCYHLALPWYSKYFPYLALIHTIILMVSS
NFWFKYPKTCSKVEHFVSILGKCFESPWTTKALSETACEDSEENKQRITGAQTLPKHVST
SSDEGSPSASTPMINKTGFKFSAEKPVIEVPSMTILDKKDGEQAKALFEKVRKFRAHVED
SDLIYKLYVVQTVIKTAKFIFILCYTANFVNAISFEHVCKPKVEHLIGYEVFECTHNMAY
MLKKLLISYISIICVYGFICLYTLFWLFRIPLKEYSFEKVREESSFSDIPDVKNDFAFLL
HMVDQYDQLYSKRFGVFLSEVSENKLREISLNHEWTFEKLRQHISRNAQDKQELHLFMLS
GVPDAVFDLTDLDVLKLELIPEAKIPAKISQMTNLQELHLCHCPAKVEQTAFSFLRDHLR
CLHVKFTDVAEIPAWVYLLKNLRELYLIGNLNSENNKMIGLESLRELRHLKILHVKSNLT
KVPSNITDVAPHLTKLVIHNDGTKLLVLNSLKKMMNVAELELQNCELERIPHAIFSLSNL
QELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVTIPPSITHVKNLESLYFSNNKLES
LPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQNLQHLHITGNKVDILPKQLFKCIKLRTL
NLGQNCITSLPEKVGQLSQLTQLELKGNCLDRLPAQLGQCRMLKKSGLVVEDHLFDTLPL
EVKEALNQDINIPFANGI
NT seq
2577 nt
NT seq
+upstream
nt +downstream
nt
atgtttacccttgcggaagttgcatcacttaatgacattcagccaacttaccgaatcctg
aaaccatggtgggatgtgtttatggattacctagctgttgttatgttaatggtagccatc
tttgcaggaaccatgcaacttaccaaagatcaggtggtctgtttgccagtattgccatct
cctgtaaattcaaaggcacatacaccaccaggaaatgccgaggtcaccaccaacatccca
aagatggaagcagccaccaaccaagaccaagatgggcggacaacaaacgacatttccttt
gggacatctgctgtgacacctgacatacctctcagagccacatatcctcgcacagatttc
gcacttccaaatcaggaggcaaagaaagagaagaaagatccaacaggtcgaaaaacaaac
ttggattttcagcaatatgtatttattaatcaaatgtgttaccatctggcccttccgtgg
tattctaagtactttccatacctagctcttatacatactattattctcatggtcagtagc
aacttttggttcaaatatcccaaaacatgctcaaaagtagaacattttgtttcaatatta
ggaaagtgctttgaatccccttggacgacaaaagcgttgtctgagacagcatgcgaagac
tcagaggaaaacaagcagagaataacaggtgcccagactctaccaaagcatgtttctacc
agcagtgatgaagggagccccagtgccagtacaccaatgatcaataaaactggctttaaa
ttttcagctgagaagcctgtgattgaagttcccagcatgacaatcctggataaaaaggat
ggagagcaggccaaagccctgtttgagaaagtgaggaagttccgtgcccatgtggaagat
agtgacttgatctataaactctatgtggtccaaacagttatcaaaacagccaagttcatt
tttattctctgctatacagcgaactttgtcaacgcaatcagctttgaacacgtctgcaag
cccaaagttgagcatctgattggttatgaggtatttgagtgcacccacaatatggcttac
atgttgaaaaagcttctcatcagttacatatccattatttgtgtttatggctttatctgc
ctctacactctcttctggttattcaggatacctttgaaggaatattctttcgaaaaagtc
agagaagagagcagttttagtgacattccagatgtcaaaaacgattttgcgttccttctt
cacatggtagaccagtatgaccagctatattccaagcgttttggtgtgttcttgtcagaa
gttagtgaaaataaacttagggaaattagtttgaaccatgagtggacatttgaaaaactc
aggcagcacatttcacgcaacgcccaggacaagcaggagttgcatctgttcatgctgtcg
ggggtgcccgatgctgtctttgacctcacagacctggatgtgctaaagcttgaactaatt
ccagaagctaaaattcctgctaagatttctcaaatgactaacctccaagagctccacctc
tgccactgccctgcaaaagttgaacagactgcttttagctttcttcgcgatcacttgaga
tgccttcacgtgaagttcactgatgtggctgaaattcctgcctgggtgtatttgctcaaa
aaccttcgagagttgtacttaataggcaatttgaactctgaaaacaataagatgatagga
cttgaatctctccgagagttgcggcaccttaagattctccacgtgaagagcaatttgacc
aaagttccctccaacattacagatgtggctccacatcttacaaagttagtcattcataat
gacggcactaaactcttggtactgaacagccttaagaaaatgatgaatgtcgctgagctg
gaactccagaactgtgagctagagagaatcccacatgctattttcagcctctctaattta
caggaactggatttaaagtccaataacattcgcacaattgaggaaatcatcagtttccag
catttaaaacgactgacttgtttaaaattatggcataacaaaattgttactattcctccc
tctattacccatgtcaaaaacttggagtcactttatttctctaacaacaagctcgaatcc
ttaccagtggcagtatttagtttacagaaactcagatgcttagatgtgagctacaacaac
atttcaatgattccaatagaaataggattgcttcagaacctgcagcatttgcatatcact
gggaacaaagtggacattctgccaaaacaattgtttaaatgcataaagttgaggactttg
aatctgggacagaactgcatcacctcactcccagagaaagttggtcagctctcccagctc
actcagctggagctgaaggggaactgcttggaccgcctgccagcccagctgggccagtgt
cggatgctcaagaaaagcgggcttgttgtggaagatcacctttttgataccctgccactc
gaagtcaaagaggcattgaatcaagacataaatattccctttgcaaatgggatttaa
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