KEGG   Homo sapiens (human): 55176
Entry
55176             CDS       T01001                                 
Symbol
SEC61A2
Name
(RefSeq) SEC61 translocon subunit alpha 2
  KO
K10956  protein transport protein SEC61 subunit alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa03060  Protein export
hsa04141  Protein processing in endoplasmic reticulum
hsa04145  Phagosome
hsa05110  Vibrio cholerae infection
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03060 Protein export
    55176 (SEC61A2)
   04141 Protein processing in endoplasmic reticulum
    55176 (SEC61A2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    55176 (SEC61A2)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05110 Vibrio cholerae infection
    55176 (SEC61A2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    55176 (SEC61A2)
  09183 Protein families: signaling and cellular processes
   02044 Secretion system [BR:hsa02044]
    55176 (SEC61A2)
Membrane trafficking [BR:hsa04131]
 Endoplasmic reticulum (ER) - Golgi transport
  Others
   SEC61 complex
    55176 (SEC61A2)
Secretion system [BR:hsa02044]
 Sec (secretion) system
  Eukaryotic Sec-SRP protein
   55176 (SEC61A2)
SSDB
Motif
Pfam: SecY Plug_translocon
Other DBs
NCBI-GeneID: 55176
NCBI-ProteinID: NP_060614
OMIM: 618271
HGNC: 17702
Ensembl: ENSG00000065665
UniProt: Q9H9S3 Q8TC24
LinkDB
Position
10:12129641..12169958
AA seq 476 aa
MGIKFLEVIKPFCAVLPEIQKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD
PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG
MIITIGQAIVYVMTGMYGDPAEMGAGICLLIIIQLFVAGLIVLLLDELLQKGYGLGSGIS
LFIATNICETIVWKAFSPTTINTGRGTEFEGAVIALFHLLATRTDKVRALREAFYRQNLP
NLMNLIATVFVFAVVIYFQGFRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSN
LYVISQMLSVRFSGNFLVNLLGQWADVSGGGPARSYPVGGLCYYLSPPESMGAIFEDPVH
VVVYIIFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRDTSMVHELNRYIPTA
AAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQAEVGGMGALFF
NT seq 1431 nt   +upstreamnt  +downstreamnt
atgggcatcaaatttttagaagttatcaaaccattctgtgcagttctaccagaaattcag
aaaccggaaaggaaaatccagtttagagagaaggttctgtggactgctataacgctcttc
attttcttagtgtgttgtcagatcccactgtttggaatcatgtcatcagattctgcagat
cctttctactggatgagagttattctggcttccaatagaggaactttaatggaattgggt
atctccccaattgtaacatctggtttgattatgcagttgttagctggagccaaaatcatt
gaagttggagatacaccgaaagatagagctttattcaatggagcccagaaactgtttggt
atgatcattaccattgggcaagccattgtgtatgtcatgacggggatgtatggggaccct
gcagaaatgggtgccggaatctgtctcctgatcatcattcagttgtttgttgctggtttg
attgtgctgctgttagatgagctgctacagaagggttacggcttggggtctgggatttcc
ctctttattgccaccaacatctgtgagaccattgtctggaaggcctttagtcccactacc
attaacactggcagaggtactgagtttgagggtgcagtcatagctctgttccatttgttg
gccaccaggacggacaaagtccgagctttacgggaggctttttatcggcagaacttaccc
aatctcatgaacctcattgctacagtttttgtgtttgctgttgttatatatttccaagga
tttcgcgttgatctgcccattaagtcggcccgttaccgaggacagtacagcagctacccc
atcaaactcttctacacctccaacatccccatcatcctccagtcggccctggtgtccaac
ctgtatgttatttcccagatgctgtctgttcgatttagtggcaactttttagtaaattta
ctaggacagtgggccgatgtcagtgggggaggacccgcacgttcttacccagttggaggc
ctttgttactatctttctcctcctgagtccatgggcgccatctttgaggatcctgtccat
gtcgttgtttatatcatcttcatgttggggtcatgtgcattcttctctaagacatggatt
gaagtgtctggttcctcagccaaagatgtagctaaacagctgaaagaacagcagatggta
atgaggggccaccgagatacctctatggttcatgagcttaataggtacatccccaccgca
gctgcgtttggcggtttgtgcattggcgccctgtcagtgctggctgacttcctgggggcc
attggatctggcactggaattctgctagcagtcactattatttaccagtattttgaaata
tttgttaaagaacaggccgaagttggtgggatgggtgctttgtttttctaa

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